SUPERFAMILY 1.75 HMM library and genome assignments server

Phosphoglycerate kinase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Phosphoglycerate kinase [ 53747]
Superfamily:   Phosphoglycerate kinase [ 53748]
Families:   Phosphoglycerate kinase [ 53749]


Superfamily statistics
Genomes (3,172) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,867 18,350 11
Proteins 3,844 18,333 11


Functional annotation
General category Metabolism
Detailed category Energy

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.95330.8106Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.067590.001608Least InformativeInherited
Biological Process (BP)single-organism cellular process0.86280.936Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process0.000000000000091460Moderately InformativeDirect
Biological Process (BP)phosphate-containing compound metabolic process0.00000000000091610.000000000003778Moderately InformativeDirect
Biological Process (BP)monocarboxylic acid metabolic process0.000000000000021460.0000431Moderately InformativeDirect
Biological Process (BP)single-organism catabolic process0.000000000020540.00000000003836Moderately InformativeDirect
Biological Process (BP)organic substance catabolic process0.0000000014790.00000000006864Moderately InformativeDirect
Biological Process (BP)carbohydrate biosynthetic process0.0003130.000007987InformativeDirect
Biological Process (BP)carbohydrate catabolic process00.000000000000003707InformativeDirect
Biological Process (BP)phosphorylation00.000001809InformativeDirect
Biological Process (BP)hexose metabolic process0.000000024140.000000001054InformativeDirect
Biological Process (BP)glucose metabolic process0.0000000056170.0000000002652Highly InformativeDirect
Biological Process (BP)glycolytic process00Highly InformativeDirect
Biological Process (BP)monosaccharide biosynthetic process0.000000000099710.0002435Highly InformativeDirect
Molecular Function (MF)binding0.00000035930.0002208Least InformativeDirect
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups00Moderately InformativeDirect
Molecular Function (MF)small molecule binding00Moderately InformativeDirect
Molecular Function (MF)anion binding00Moderately InformativeDirect
Molecular Function (MF)carbohydrate derivative binding00Moderately InformativeDirect
Molecular Function (MF)nucleotide binding00InformativeDirect
Molecular Function (MF)kinase activity00InformativeDirect
Molecular Function (MF)purine ribonucleoside binding00InformativeDirect
Molecular Function (MF)purine ribonucleoside triphosphate binding0.00000012350.0000003392InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.8106 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.001608 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.936 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) phosphate-containing compound metabolic process 0.000000000003778 Moderately Informative Direct
Biological Process (BP) monocarboxylic acid metabolic process 0.0000431 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.00000000003836 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.00000000006864 Moderately Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0.000007987 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.000000000000003707 Informative Direct
Biological Process (BP) phosphorylation 0.000001809 Informative Direct
Biological Process (BP) hexose metabolic process 0.000000001054 Informative Direct
Biological Process (BP) glucose metabolic process 0.0000000002652 Highly Informative Direct
Biological Process (BP) glycolytic process 0 Highly Informative Direct
Biological Process (BP) monosaccharide biosynthetic process 0.0002435 Highly Informative Direct
Molecular Function (MF) binding 0.0002208 Least Informative Direct
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0 Moderately Informative Direct
Molecular Function (MF) nucleotide binding 0 Informative Direct
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0000003392 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)cotyledon0Moderately InformativeDirect
Plant ANatomical entity (PAN)inflorescence meristem0Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processGlycolysis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)carbohydrate degradation0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)glycolysis0InformativeDirect
UniPathway (UP)Calvin cycle0.00000001254Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR001576 SSF53748 Protein matches
Abstract

This entry represents the full PGK enzyme.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Phosphoglycerate kinase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 9 hidden Markov models representing the Phosphoglycerate kinase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]