SUPERFAMILY 1.75 HMM library and genome assignments server


ALDH-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   ALDH-like [ 53719]
Superfamily:   ALDH-like [ 53720] (2)
Families:   ALDH-like [ 53721] (5)
  L-histidinol dehydrogenase HisD [ 69602]


Superfamily statistics
Genomes (3,019) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,956 176,906 20
Proteins 34,496 176,078 20


Functional annotation
General category Metabolism
Detailed category Redox

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)developmental process0.6241Least InformativeInherited
Biological Process (BP)multicellular organismal process0.93861Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)response to stimulus0.54951Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.68450.525Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.029792.05e-05Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process6.298e-110Moderately InformativeDirect
Biological Process (BP)organic hydroxy compound metabolic process6.505e-087.686e-06Moderately InformativeDirect
Biological Process (BP)organ development0.10181Moderately InformativeInherited
Biological Process (BP)cellular nitrogen compound biosynthetic process0.83631Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.011970.5712Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.76810.3001Moderately InformativeInherited
Biological Process (BP)system process0.13180.8401Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.018250.2224Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.27810.216Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.60960.003482Moderately InformativeInherited
Biological Process (BP)organonitrogen compound catabolic process0.0027361.98e-05Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process0.0710.09701Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process11Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.16330.4132Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.64471Moderately InformativeInherited
Biological Process (BP)tissue development0.21361Moderately InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.44760.2368Moderately InformativeInherited
Biological Process (BP)organic cyclic compound biosynthetic process0.43130.4519Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.45440.01719Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.0020435.928e-07Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.92381Moderately InformativeInherited
Biological Process (BP)cellular aldehyde metabolic process00InformativeDirect
Biological Process (BP)isoprenoid metabolic process6.509e-154.592e-12InformativeDirect
Biological Process (BP)regulation of hormone levels2.294e-121.631e-10InformativeDirect
Biological Process (BP)sensory organ development0.00026570.3052InformativeInherited
Biological Process (BP)embryonic organ development9.681e-060.0415InformativeInherited
Biological Process (BP)embryonic morphogenesis0.00012010.2968InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.19160.1253InformativeInherited
Biological Process (BP)secondary metabolic process0.49541InformativeInherited
Biological Process (BP)synaptic transmission0.13160.5469InformativeInherited
Biological Process (BP)alcohol metabolic process0.1180.9491InformativeInherited
Biological Process (BP)cellular amide metabolic process0.2170.03461InformativeInherited
Biological Process (BP)response to inorganic substance0.28580.04237InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.75930.0088InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process11InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.0060680.003201InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.031650.662InformativeInherited
Biological Process (BP)organ morphogenesis0.0048110.9689InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.068581InformativeInherited
Biological Process (BP)tissue morphogenesis0.001660.4438InformativeInherited
Biological Process (BP)epithelium development0.032570.9663InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process11InformativeInherited
Biological Process (BP)retinoid metabolic process00Highly InformativeDirect
Biological Process (BP)amino-acid betaine metabolic process3.321e-150Highly InformativeDirect
Biological Process (BP)polyamine metabolic process9.936e-050.0001176Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process7.64e-072.904e-05Highly InformativeDirect
Biological Process (BP)glutamine family amino acid catabolic process0.00028281.852e-06Highly InformativeDirect
Biological Process (BP)response to water deprivation0.00011691.254e-05Highly InformativeDirect
Biological Process (BP)cellular hormone metabolic process2.76e-111.031e-11Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.00013154.09e-07Highly InformativeDirect
Biological Process (BP)embryonic organ morphogenesis1.049e-070.003413Highly InformativeInherited
Biological Process (BP)eye morphogenesis3.122e-060.006751Highly InformativeInherited
Biological Process (BP)antibiotic biosynthetic process0.0017110.0001663Highly InformativeInherited
Biological Process (BP)secondary metabolite biosynthetic process0.21810.944Highly InformativeInherited
Biological Process (BP)regulation of neurotransmitter levels0.032490.004081Highly InformativeInherited
Biological Process (BP)nucleobase metabolic process0.00097070.01067Highly InformativeInherited
Biological Process (BP)cellular biogenic amine catabolic process0.19460.05101Highly InformativeInherited
Biological Process (BP)branched-chain amino acid metabolic process0.00064680.1034Highly InformativeInherited
Biological Process (BP)glutamate metabolic process0.081010.0006307Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.0001890.004598Highly InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)anion binding0.012080.03244Moderately InformativeInherited
Molecular Function (MF)cofactor binding4.259e-140InformativeDirect
Molecular Function (MF)nucleotide binding0.45460.5354InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on CH-OH group of donors11InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on the aldehyde or oxo group of donors00Highly InformativeDirect
Molecular Function (MF)hormone binding1.651e-057.297e-05Highly InformativeDirect
Molecular Function (MF)NAD binding9.571e-111.687e-12Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.74410.2223Highly InformativeInherited
Cellular Component (CC)cytoplasmic part0.00079442.517e-09Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.17460.4235Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) nitrogen compound metabolic process 2.05e-05 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.525 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 5.928e-07 Moderately Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 1.98e-05 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 7.686e-06 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.8257 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.6852 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.5712 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.3001 Moderately Informative Inherited
Biological Process (BP) system process 0.8401 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.2224 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.216 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.003482 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.09701 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound catabolic process 0.1948 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4132 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.2368 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.4519 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.01719 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular aldehyde metabolic process 0 Informative Direct
Biological Process (BP) isoprenoid metabolic process 4.592e-12 Informative Direct
Biological Process (BP) regulation of hormone levels 1.631e-10 Informative Direct
Biological Process (BP) protein complex assembly 0.0433 Informative Inherited
Biological Process (BP) sensory organ development 0.3052 Informative Inherited
Biological Process (BP) embryonic organ development 0.0415 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.2968 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.1253 Informative Inherited
Biological Process (BP) secondary metabolic process 1 Informative Inherited
Biological Process (BP) synaptic transmission 0.5469 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.9491 Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.03461 Informative Inherited
Biological Process (BP) response to inorganic substance 0.04237 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.0088 Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 1 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.003201 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.662 Informative Inherited
Biological Process (BP) organ morphogenesis 0.9689 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.4438 Informative Inherited
Biological Process (BP) epithelium development 0.9663 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 1 Informative Inherited
Biological Process (BP) retinoid metabolic process 0 Highly Informative Direct
Biological Process (BP) glutamate metabolic process 0.0006307 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 0 Highly Informative Direct
Biological Process (BP) polyamine metabolic process 0.0001176 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 2.904e-05 Highly Informative Direct
Biological Process (BP) glutamine family amino acid catabolic process 1.852e-06 Highly Informative Direct
Biological Process (BP) response to water deprivation 1.254e-05 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 0.0001663 Highly Informative Direct
Biological Process (BP) cellular hormone metabolic process 1.031e-11 Highly Informative Direct
Biological Process (BP) protein tetramerization 2.254e-09 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 4.09e-07 Highly Informative Direct
Biological Process (BP) protein homooligomerization 0.02499 Highly Informative Inherited
Biological Process (BP) embryonic organ morphogenesis 0.003413 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.006751 Highly Informative Inherited
Biological Process (BP) secondary metabolite biosynthetic process 0.944 Highly Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 0.004081 Highly Informative Inherited
Biological Process (BP) nucleobase metabolic process 0.01067 Highly Informative Inherited
Biological Process (BP) cellular biogenic amine catabolic process 0.05101 Highly Informative Inherited
Biological Process (BP) branched-chain amino acid metabolic process 0.1034 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.004598 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.03244 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) nucleotide binding 0.5354 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 0 Highly Informative Direct
Molecular Function (MF) hormone binding 7.297e-05 Highly Informative Direct
Molecular Function (MF) NAD binding 1.687e-12 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.2223 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 0.004745 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 2.517e-09 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.4235 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.001109 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) mitochondrial matrix 0.0002368 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0Moderately InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as accep0.9278InformativeInherited
Enzyme Commission (EC)Histidinol dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)Formyltetrahydrofolate dehydrogenase1.588e-10Highly InformativeDirect
Enzyme Commission (EC)Glutamate 5-kinase4.896e-05Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body phenotype0.2886Least InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.00121Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal embryogenesis/ development1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal anterior eye segment morphology0.1745InformativeInherited
Mammalian Phenotype (MP)abnormal lens morphology0.0005726Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)alimentary system0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)intestine0.000262Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0.005805Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.008183Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.03173Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence0.1793Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll0.7602Least InformativeInherited
Plant ANatomical entity (PAN)inflorescence meristem0.0007226Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)Acting on the aldehyde or oxo group of donors0InformativeDirect
Enzyme Commission (EC)Acting on the CH-NH group of donors1InformativeInherited
Enzyme Commission (EC)With a quinone or similar compound as acceptor4.488e-05Highly InformativeDirect
Enzyme Commission (EC)Phosphotransferases with a carboxyl group as acceptor0.8932Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processAromatic hydrocarbons catabolism0.00093InformativeDirect
Biological processArginine metabolism0Highly InformativeDirect
Biological processHistidine biosynthesis5.876e-11Highly InformativeDirect
Biological processLuminescence6.46e-09Highly InformativeDirect
Cellular componentCytoplasm8.177e-15Least InformativeDirect
Cellular componentMitochondrion0.0003494Moderately InformativeDirect
DomainTransit peptide1.426e-11Moderately InformativeDirect
Molecular functionZinc1.492e-05Least InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionPotassium0InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationOxidation0Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)amino-acid degradation1.341e-15Moderately InformativeDirect
UniPathway (UP)organic acid metabolism5.709e-05Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)L-arginine degradation0InformativeDirect
UniPathway (UP)choline metabolism0InformativeDirect
UniPathway (UP)L-histidine biosynthesis2.816e-11InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis4.729e-10InformativeDirect
UniPathway (UP)organic acid degradation1.49e-07InformativeDirect
UniPathway (UP)putrescine metabolism0.766InformativeInherited
UniPathway (UP)amine and polyamine degradation1InformativeInherited
UniPathway (UP)polyol degradation1InformativeInherited
UniPathway (UP)myo-inositol degradation into acetyl-CoA0Highly InformativeDirect
UniPathway (UP)L-proline biosynthesis0Highly InformativeDirect
UniPathway (UP)L-arginine degradation via AST pathway0Highly InformativeDirect
UniPathway (UP)putrescine degradation0Highly InformativeDirect
UniPathway (UP)betaine biosynthesis0Highly InformativeDirect
UniPathway (UP)L-proline degradation1.201e-09Highly InformativeDirect
UniPathway (UP)bacterial bioluminescence1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ALDH-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 15 hidden Markov models representing the ALDH-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]