SUPERFAMILY 1.75 HMM library and genome assignments server

Nucleotide-diphospho-sugar transferases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Nucleotide-diphospho-sugar transferases [ 53447]
Superfamily:   Nucleotide-diphospho-sugar transferases [ 53448] (19)
Families:   Spore coat polysaccharide biosynthesis protein SpsA [ 53449]
  beta 1,4 galactosyltransferase (b4GalT1) [ 53452]
  Galactosyltransferase LgtC [ 53458]
  Glycogenin [ 75273]
  alpha-1,3-galactosyltransferase-like [ 64131] (3)
  UDP-glucose pyrophosphorylase [ 53461] (3)
  glucose-1-phosphate thymidylyltransferase [ 53464] (3)
  1,3-glucuronyltransferase [ 53467] (2)
  N-acetylglucosaminyltransferase I [ 64136]
  Exostosin [ 89760]
  Molybdenum cofactor biosynthesis protein MobA [ 53470]
  Cytidylytransferase [ 68901] (6)
  Glycolipid 2-alpha-mannosyltransferase [ 102609]
  Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain [ 117702]
  MGS-like [ 142691]
  TTHA0179-like [ 159717]
  mannose-1-phosphate guanylyl transferase [ 159720]
  MM2497-like [ 159723]
  Glycosylating toxin catalytic domain-like [ 159726] (3)


Superfamily statistics
Genomes (3,204) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 92,619 369,448 97
Proteins 90,993 363,466 97


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process00Least InformativeDirect
Biological Process (BP)cellular macromolecule metabolic process0.0000021210.000000000000003707Least InformativeDirect
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.000070960.0000000009496Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.68010.6527Least InformativeInherited
Biological Process (BP)protein metabolic process0.39190.000214Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.73631Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process00Moderately InformativeDirect
Biological Process (BP)carbohydrate derivative metabolic process00Moderately InformativeDirect
Biological Process (BP)sulfur compound metabolic process0.0088110.000000003725Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.98811Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.081430.0001838Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.00067410.07322Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.0035520.2957Moderately InformativeInherited
Biological Process (BP)lipid metabolic process0.0000000000052880.003678Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction11Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.0083960.000001503Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.24850.00006376Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.32440.00000007766Moderately InformativeInherited
Biological Process (BP)polysaccharide metabolic process0.000000000062830InformativeDirect
Biological Process (BP)membrane lipid metabolic process0.00000000000021180InformativeDirect
Biological Process (BP)carbohydrate biosynthetic process0.0000000062440InformativeDirect
Biological Process (BP)cellular carbohydrate metabolic process0.00000000000031480InformativeDirect
Biological Process (BP)cell wall organization or biogenesis0.000010770InformativeDirect
Biological Process (BP)liposaccharide metabolic process00InformativeDirect
Biological Process (BP)regulation of cell proliferation0.10211InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.57051InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.17640.0001991InformativeInherited
Biological Process (BP)phospholipid metabolic process0.0024050.136InformativeInherited
Biological Process (BP)glycerolipid metabolic process0.74121InformativeInherited
Biological Process (BP)hexose metabolic process0.013630.06865InformativeInherited
Biological Process (BP)galactose metabolic process0.00000048270.0000002078Highly InformativeDirect
Biological Process (BP)aminoglycan biosynthetic process0.0000000000000079360Highly InformativeDirect
Biological Process (BP)protein glycosylation00Highly InformativeDirect
Biological Process (BP)lipopolysaccharide metabolic process0.000022940.000295Highly InformativeDirect
Biological Process (BP)nucleotide-sugar metabolic process0.0000000012760Highly InformativeDirect
Biological Process (BP)sphingolipid biosynthetic process0.000000014430.0000000000004894Highly InformativeDirect
Biological Process (BP)cellular polysaccharide biosynthetic process0.0000011880Highly InformativeDirect
Biological Process (BP)post-translational protein modification0.00025590Highly InformativeDirect
Biological Process (BP)glycosaminoglycan metabolic process01Highly InformativeInherited
Biological Process (BP)negative regulation of cell proliferation0.0017650.8148Highly InformativeInherited
Biological Process (BP)extracellular matrix organization10Highly InformativeInherited
Biological Process (BP)glycosphingolipid metabolic process0.007890.000006316Highly InformativeInherited
Biological Process (BP)glycolipid biosynthetic process0.000023450.02786Highly InformativeInherited
Biological Process (BP)glycerophospholipid biosynthetic process0.10760.1596Highly InformativeInherited
Biological Process (BP)phosphatidylinositol metabolic process0.0000000071820.002986Highly InformativeInherited
Biological Process (BP)cell wall macromolecule biosynthetic process0.047260.000004877Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups11Moderately InformativeInherited
Molecular Function (MF)cation binding0.029730.02894Moderately InformativeInherited
Molecular Function (MF)magnesium ion binding0.00014670.00009879InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups00InformativeDirect
Molecular Function (MF)nucleotidyltransferase activity00InformativeDirect
Molecular Function (MF)UDP-glycosyltransferase activity0.0004680Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring hexosyl groups0.00000000016380Highly InformativeDirect
Cellular Component (CC)membrane0.0025210.08238Least InformativeInherited
Cellular Component (CC)protein complex11Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.050070.0000000000004814Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.57110.4125Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.18410.4573Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.0000050050.00000000000003132Moderately InformativeDirect
Cellular Component (CC)bounding membrane of organelle0.0000000021990Moderately InformativeDirect
Cellular Component (CC)membrane region0.12010.4656Moderately InformativeInherited
Cellular Component (CC)transferase complex0.26331Moderately InformativeInherited
Cellular Component (CC)Golgi apparatus00InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 0.000214 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.000000000000003707 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000000009496 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.6527 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 0.000001503 Moderately Informative Direct
Biological Process (BP) sulfur compound metabolic process 0.000000003725 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.00000007766 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0001838 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0.00006376 Moderately Informative Direct
Biological Process (BP) tissue development 0.5375 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.07814 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) reproductive process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.003678 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.06747 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.2957 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.07322 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 1 Moderately Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0 Informative Direct
Biological Process (BP) membrane lipid metabolic process 0 Informative Direct
Biological Process (BP) carbohydrate biosynthetic process 0 Informative Direct
Biological Process (BP) growth 0.0002409 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 0.0001991 Informative Direct
Biological Process (BP) regulation of body fluid levels 0.00004215 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0 Informative Direct
Biological Process (BP) liposaccharide metabolic process 0 Informative Direct
Biological Process (BP) tissue morphogenesis 0.01649 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) tube development 0.5929 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) central nervous system development 0.8218 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.06508 Informative Inherited
Biological Process (BP) regulation of cell proliferation 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.3796 Informative Inherited
Biological Process (BP) cardiovascular system development 0.9278 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.06491 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) multi-multicellular organism process 0.00107 Informative Inherited
Biological Process (BP) cellular metabolic compound salvage 1 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 0.07624 Informative Inherited
Biological Process (BP) phospholipid metabolic process 0.136 Informative Inherited
Biological Process (BP) glycerolipid metabolic process 1 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.9486 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.4215 Informative Inherited
Biological Process (BP) hexose metabolic process 0.06865 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.006309 Informative Inherited
Biological Process (BP) galactose metabolic process 0.0000002078 Highly Informative Direct
Biological Process (BP) aminoglycan biosynthetic process 0 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 0.000000000004406 Highly Informative Direct
Biological Process (BP) energy reserve metabolic process 0.000005232 Highly Informative Direct
Biological Process (BP) translational initiation 0.0000000021 Highly Informative Direct
Biological Process (BP) protein glycosylation 0 Highly Informative Direct
Biological Process (BP) glycosphingolipid metabolic process 0.000006316 Highly Informative Direct
Biological Process (BP) lipopolysaccharide metabolic process 0.000295 Highly Informative Direct
Biological Process (BP) nucleotide-sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) photorespiration 0.0004218 Highly Informative Direct
Biological Process (BP) glial cell differentiation 0.0007371 Highly Informative Direct
Biological Process (BP) sphingolipid biosynthetic process 0.0000000000004894 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) cellular polysaccharide biosynthetic process 0 Highly Informative Direct
Biological Process (BP) post-translational protein modification 0 Highly Informative Direct
Biological Process (BP) cell wall macromolecule biosynthetic process 0.000004877 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 0 Highly Informative Direct
Biological Process (BP) epithelial tube formation 0.0006467 Highly Informative Direct
Biological Process (BP) heart morphogenesis 0.1355 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 1 Highly Informative Inherited
Biological Process (BP) stem cell development 0.409 Highly Informative Inherited
Biological Process (BP) mesenchyme development 0.1014 Highly Informative Inherited
Biological Process (BP) cell wall polysaccharide metabolic process 1 Highly Informative Inherited
Biological Process (BP) glycosaminoglycan metabolic process 1 Highly Informative Inherited
Biological Process (BP) negative regulation of cell proliferation 0.8148 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.4543 Highly Informative Inherited
Biological Process (BP) cellular component assembly involved in morphogenesis 0.7508 Highly Informative Inherited
Biological Process (BP) respiratory system development 0.08827 Highly Informative Inherited
Biological Process (BP) developmental growth 0.1028 Highly Informative Inherited
Biological Process (BP) cell growth 0.07724 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 0.07349 Highly Informative Inherited
Biological Process (BP) glycolipid biosynthetic process 0.02786 Highly Informative Inherited
Biological Process (BP) glycerophospholipid biosynthetic process 0.1596 Highly Informative Inherited
Biological Process (BP) phosphatidylinositol metabolic process 0.002986 Highly Informative Inherited
Biological Process (BP) regulation of translation 0.2472 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1521 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) cation binding 0.02894 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 1 Moderately Informative Inherited
Molecular Function (MF) magnesium ion binding 0.00009879 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct
Molecular Function (MF) RNA binding 0.8426 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0.000006982 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0.000000000002498 Highly Informative Direct
Molecular Function (MF) UDP-glycosyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring hexosyl groups 0 Highly Informative Direct
Molecular Function (MF) manganese ion binding 0.000000001529 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 1 Highly Informative Inherited
Molecular Function (MF) adenylyltransferase activity 1 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.0000000000004814 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) membrane 0.08238 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.4125 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.4573 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0.00000000000003132 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0 Moderately Informative Direct
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) transferase complex 1 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 0.06269 Moderately Informative Inherited
Cellular Component (CC) membrane region 0.4656 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) endoplasmic reticulum membrane 0.0002233 Informative Direct
Cellular Component (CC) Golgi apparatus 0 Informative Direct
Cellular Component (CC) contractile fiber part 0.3025 Informative Inherited
Cellular Component (CC) integral component of membrane 0.02143 Informative Inherited
Cellular Component (CC) trans-Golgi network 0.00000000006817 Highly Informative Direct
Cellular Component (CC) integral component of organelle membrane 0.0000003259 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases0.00000000007521Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0.8741Moderately InformativeInherited
Enzyme Commission (EC)Transferring other groups1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)Cellulose synthase (UDP-forming)0Highly InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0.00000001082Highly InformativeDirect
Enzyme Commission (EC)Transferases for other substituted phosphate group0.3125Highly InformativeInherited

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.711Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.0003109Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the globe0.005063Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1471Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cornea0.1649InformativeInherited
Phenotypic Abnormality (PA)Joint laxity0.0007488Highly InformativeDirect
Phenotypic Abnormality (PA)Microcornea0.0009544Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal basement membrane morphology0.0007074Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)early embryonic lethal0.1426Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.4931Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.7507Moderately InformativeInherited
Worm Phenotype (WP)alimentary system development variant0.02712InformativeInherited
Worm Phenotype (WP)vulva development variant0.08713InformativeInherited
Worm Phenotype (WP)one cell arrest early emb0.0002376Highly InformativeDirect
Worm Phenotype (WP)pharyngeal development variant0.000365Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)morphology0.2482Moderately InformativeInherited
Yeast Phenotype (YP)subcellular morphology0.229InformativeInherited
Yeast Phenotype (YP)chitin deposition0.00009108Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0.1403Least InformativeInherited
Fly Anatomy (FA)anatomical group0.3746Least InformativeInherited
Fly Anatomy (FA)larva0.3971Least InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.07103Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval integumentary system0.007181InformativeInherited
Fly Anatomy (FA)denticle belt0.0001232Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.388Least InformativeInherited
Zebrafish Anatomy (ZA)stromal cell0.0001397InformativeDirect

Document: ZA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)leaf0.2732Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.3262Least InformativeInherited
Plant ANatomical entity (PAN)shoot axis0.7017Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue0.000000001524InformativeDirect
Plant ANatomical entity (PAN)vascular system0.00000001953InformativeDirect
Plant ANatomical entity (PAN)trichome0.00000000002171Highly InformativeDirect
Plant ANatomical entity (PAN)leaf epidermis0.000003053Highly InformativeDirect
Plant ANatomical entity (PAN)phloem0.0001092Highly InformativeDirect
Plant ANatomical entity (PAN)mesophyll1Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Hexosyltransferases0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen1InformativeInherited
Enzyme Commission (EC)Pentosyltransferases1InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Intramolecular transferases (mutases)1InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0.00000007634Highly InformativeDirect
Enzyme Commission (EC)Transferases for other substituted phosphate groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)alimentary tract and metabolism0.08523Least InformativeInherited
Drugbank ATC_code (DB)sensory organs0.1378Least InformativeInherited
Drugbank ATC_code (DB)musculo-skeletal system0.001425Moderately InformativeInherited
Drugbank ATC_code (DB)genito urinary system and sex hormones0.01538Moderately InformativeInherited
Drugbank ATC_code (DB)antiinflammatory and antirheumatic products, non-steroids0.00001482InformativeDirect
Drugbank ATC_code (DB)ascorbic acid (vitamin c), incl. combinations0.00002452InformativeDirect
Drugbank ATC_code (DB)ascorbic acid0.00002452InformativeDirect
Drugbank ATC_code (DB)ascorbic acid0.00002452InformativeDirect
Drugbank ATC_code (DB)glucosamine0.000000005831Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processLipid metabolism1Moderately InformativeInherited
Biological processCell shape0InformativeDirect
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processAntibiotic resistance0.000000000000002085InformativeDirect
Biological processLipid biosynthesis0.1068InformativeInherited
Biological processGlycogen biosynthesis0Highly InformativeDirect
Biological processIsoprene biosynthesis0Highly InformativeDirect
Biological processLipopolysaccharide biosynthesis0Highly InformativeDirect
Biological processMolybdenum cofactor biosynthesis0Highly InformativeDirect
Biological processPeptidoglycan synthesis0Highly InformativeDirect
Biological processNodulation0.0000000007526Highly InformativeDirect
Biological processLipid A biosynthesis0.000000004064Highly InformativeDirect
Biological processSphingolipid metabolism0.000001045Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCytoplasm0.00001169Least InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentEndoplasmic reticulum0.000000000000007577Moderately InformativeDirect
Cellular componentPlastid1Moderately InformativeInherited
DiseaseDystroglycanopathy0.000000001624Highly InformativeDirect
DiseaseCongenital muscular dystrophy0.000000004719Highly InformativeDirect
DomainTransmembrane0Least InformativeDirect
DomainRepeat3.091e-16Least InformativeDirect
DomainSignal-anchor0InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding1Least InformativeInherited
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Molecular functionLectin0InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)lipid metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)biopolymer biosynthesis0Moderately InformativeDirect
UniPathway (UP)metabolic intermediate biosynthesis0Moderately InformativeDirect
UniPathway (UP)lipid biosynthesis0Moderately InformativeDirect
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism0Moderately InformativeDirect
UniPathway (UP)cellular component biogenesis0Moderately InformativeDirect
UniPathway (UP)membrane lipid metabolism0Moderately InformativeDirect
UniPathway (UP)carbohydrate biosynthesis1Moderately InformativeInherited
UniPathway (UP)cell wall metabolism1Moderately InformativeInherited
UniPathway (UP)protein glycosylation0InformativeDirect
UniPathway (UP)isoprenoid biosynthesis0InformativeDirect
UniPathway (UP)lipopolysaccharide biosynthesis0.000000007194InformativeDirect
UniPathway (UP)nucleotide-sugar biosynthesis0.9702InformativeInherited
UniPathway (UP)pigment biosynthesis1InformativeInherited
UniPathway (UP)glycolipid biosynthesis1InformativeInherited
UniPathway (UP)isopentenyl diphosphate biosynthesis via DXP pathway0Highly InformativeDirect
UniPathway (UP)coenzyme F420 biosynthesis0Highly InformativeDirect
UniPathway (UP)UDP-N-acetyl-alpha-D-glucosamine biosynthesis0Highly InformativeDirect
UniPathway (UP)glycosaminoglycan metabolism0.00009211Highly InformativeDirect
UniPathway (UP)carotenoid biosynthesis1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 43 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nucleotide-diphospho-sugar transferases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 43 hidden Markov models representing the Nucleotide-diphospho-sugar transferases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]