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tRNA-intron endonuclease catalytic domain-like superfamily
SCOP classification
Superfamily statistics
Functional annotation
| General category | Information |
| Detailed category | Translation |
Document: Function annotation of SCOP domain superfamilies
Gene Ontology (high-coverage) (show details)
Highlighted in gray are those with either FDR_singleton>0.001 or FDR_all>0.001
|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
tRNA splicing, via endonucleolytic cleavage and ligation |
2.076e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
RNA splicing, via endonucleolytic cleavage and ligation |
1.806e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
tRNA processing |
1.008e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
RNA splicing |
1.057e-07 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
ncRNA metabolic process |
1.24e-06 |
1.444 |
-- |
DIRECT |
| Biological Process (BP) |
RNA processing |
2.062e-05 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
0.01778 |
0.7305 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing || RNA splicing, via endonucleolytic cleavage and ligation || RNA processing || ncRNA processing || ncRNA metabolic process || RNA metabolic process || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
0.03923 |
0.585 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing || RNA splicing, via endonucleolytic cleavage and ligation || RNA processing || ncRNA processing || ncRNA metabolic process || RNA metabolic process || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
macromolecule metabolic process |
0.2426 |
0.4634 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA metabolic process || RNA splicing || RNA processing || ncRNA processing || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
primary metabolic process |
0.5702 |
0.2976 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA metabolic process || RNA splicing || RNA processing || ncRNA processing || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
cellular metabolic process |
0.6433 |
0.2708 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA splicing || RNA processing || tRNA splicing, via endonucleolytic cleavage and ligation || RNA metabolic process || ncRNA processing || tRNA processing |
| Biological Process (BP) |
organic substance metabolic process |
0.6822 |
0.2676 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA splicing || RNA processing || tRNA splicing, via endonucleolytic cleavage and ligation || RNA metabolic process || ncRNA processing || tRNA processing |
| Biological Process (BP) |
metabolic process |
0.7809 |
0.2411 |
-- |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA splicing || RNA processing || tRNA splicing, via endonucleolytic cleavage and ligation || RNA metabolic process || ncRNA processing || tRNA processing |
| Biological Process (BP) |
nucleic acid metabolic process |
0.00524 |
0.9066 |
-- |
INHERITED FROM: RNA processing || tRNA metabolic process || ncRNA processing || ncRNA metabolic process || RNA splicing || RNA metabolic process || tRNA processing || RNA splicing, via endonucleolytic cleavage and ligation || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
cellular process |
1 |
0.1415 |
-- |
INHERITED FROM: RNA splicing, via endonucleolytic cleavage and ligation || RNA metabolic process || ncRNA processing || tRNA metabolic process || ncRNA metabolic process || RNA splicing || RNA processing || tRNA splicing, via endonucleolytic cleavage and ligation || tRNA processing |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: RNA splicing, via endonucleolytic cleavage and ligation || RNA metabolic process || ncRNA processing || tRNA metabolic process || RNA splicing || RNA processing || tRNA splicing, via endonucleolytic cleavage and ligation || tRNA processing || ncRNA metabolic process |
| Biological Process (BP) |
heterocycle metabolic process |
0.0315 |
0.6308 |
Least Informative |
INHERITED FROM: tRNA metabolic process || RNA splicing || RNA splicing, via endonucleolytic cleavage and ligation || RNA processing || ncRNA processing || ncRNA metabolic process || RNA metabolic process || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
cellular macromolecule metabolic process |
0.1704 |
0.4976 |
Least Informative |
INHERITED FROM: tRNA metabolic process || RNA splicing || RNA splicing, via endonucleolytic cleavage and ligation || RNA processing || ncRNA processing || ncRNA metabolic process || RNA metabolic process || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
0.0353 |
0.6271 |
Least Informative |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA metabolic process || RNA splicing || RNA processing || ncRNA processing || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
organic cyclic compound metabolic process |
0.04829 |
0.5817 |
Least Informative |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA metabolic process || RNA splicing || RNA processing || ncRNA processing || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
nitrogen compound metabolic process |
0.07499 |
0.5171 |
Least Informative |
INHERITED FROM: tRNA metabolic process || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA metabolic process || RNA metabolic process || RNA splicing || RNA processing || ncRNA processing || tRNA processing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
RNA metabolic process |
0.0005847 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
gene expression |
0.001065 |
0.8729 |
Moderately Informative |
INHERITED FROM: RNA processing || tRNA processing || RNA splicing, via endonucleolytic cleavage and ligation || ncRNA processing || RNA splicing || tRNA splicing, via endonucleolytic cleavage and ligation |
| Biological Process (BP) |
tRNA metabolic process |
1.695e-08 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
ncRNA processing |
2.349e-07 |
1.553 |
Informative |
DIRECT |
| Molecular Function (MF) |
catalytic activity |
0.4616 |
0.2686 |
-- |
INHERITED FROM: hydrolase activity, acting on ester bonds || nuclease activity |
| Molecular Function (MF) |
molecular_function |
0.5563 |
0 |
-- |
INHERITED FROM: nuclease activity || hydrolase activity, acting on ester bonds |
| Molecular Function (MF) |
hydrolase activity |
0.01297 |
0.6657 |
Least Informative |
INHERITED FROM: nuclease activity || hydrolase activity, acting on ester bonds |
| Molecular Function (MF) |
hydrolase activity, acting on ester bonds |
4.871e-05 |
1.122 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
nuclease activity |
8.83e-09 |
1.565 |
Informative |
DIRECT |
Document: GO annotation of SCOP domains
Enzyme Commission (EC) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: EC annotation of SCOP domains
Yeast Phenotype (YP) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: YP annotation of SCOP domains
Xenopus Anatomy (XA) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: XA annotation of SCOP domains
Enzyme Commission (EC) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: EC annotation of SCOP domains
UniProtKB KeyWords (KW) (show details)
Highlighted in gray are those with FDR_all>0.001
Document: KW annotation of SCOP domains
InterPro annotation
| Cross references | IPR006677 SSF53032 Protein matches |
| Abstract | tRNA-intron endonucleases cleave pre-tRNA producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron [ 9200602]. This entry is for C-terminal domain of tRNA-intron endonuclease. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]
Internal database links
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 4 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a tRNA-intron endonuclease catalytic domain-like domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 4 hidden Markov models representing the tRNA-intron endonuclease catalytic domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]
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