SUPERFAMILY 1.73 HMM library and genome assignments server


UDP-glucose/GDP-mannose dehydrogenase C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   Adenine nucleotide alpha hydrolase-like [ 52373] (3)
  core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
Superfamily:   UDP-glucose/GDP-mannose dehydrogenase C-terminal domain [ 52413]
Families:   UDP-glucose/GDP-mannose dehydrogenase C-terminal domain [ 52414] (2)


Superfamily statistics
Genomes (933) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 1,776 2,225 3
Proteins 1,773 2,225 3


Functional annotation
General category Metabolism
Detailed category Energy

Function annotation of SCOP domain superfamilies
InterPro annotation
Cross references IPR014027 SSF52413 Protein matches
Abstract

This entry represents the C-terminal substrate-binding domain of these enzymes. Structural studies indicate that this domain forms an incomplete dinucleotide binding fold [PubMed10841783, PubMed12705829].


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a UDP-glucose/GDP-mannose dehydrogenase C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the UDP-glucose/GDP-mannose dehydrogenase C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]