SUPERFAMILY 1.75 HMM library and genome assignments server


Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  A4 beta-galactosidase middle domain [ 82351]
  DJ-1/PfpI [ 52325] (9)
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  ThuA-like [ 110486]
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  HTS-like [ 142077]
  STM3548-like [ 159492]


Superfamily statistics
Genomes (3,213) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 47,023 113,729 68
Proteins 46,574 113,381 68


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.00099681.605e-14Least InformativeDirect
Biological Process (BP)single-organism metabolic process4.886e-050Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.048981.217e-10Least InformativeInherited
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.83071Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.026147.116e-11Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.0081642.533e-11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.0073523.094e-10Least InformativeInherited
Biological Process (BP)response to stimulus0.9151Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process3.389e-060Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process3.327e-090Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process5.328e-100Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process9.916e-080Moderately InformativeDirect
Biological Process (BP)single-organism biosynthetic process2.077e-081.876e-10Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process4.33e-080Moderately InformativeDirect
Biological Process (BP)organonitrogen compound biosynthetic process6.115e-070Moderately InformativeDirect
Biological Process (BP)positive regulation of molecular function0.0037210.244Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus1.296e-050.01456Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.12381Moderately InformativeInherited
Biological Process (BP)regulation of programmed cell death0.0025780.6033Moderately InformativeInherited
Biological Process (BP)cellular response to stress3.902e-060.003711Moderately InformativeInherited
Biological Process (BP)regulation of localization0.093841Moderately InformativeInherited
Biological Process (BP)ion transport0.06560.8789Moderately InformativeInherited
Biological Process (BP)organic substance transport0.16780.9409Moderately InformativeInherited
Biological Process (BP)sulfur compound metabolic process0.0049980.03481Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.011370.03499Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process11Moderately InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.0055430.2956Moderately InformativeInherited
Biological Process (BP)system process0.047791Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0090940.0008228Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process7.084e-088.593e-14InformativeDirect
Biological Process (BP)response to oxidative stress7.694e-155.721e-14InformativeDirect
Biological Process (BP)response to inorganic substance5.577e-057.432e-08InformativeDirect
Biological Process (BP)cellular response to oxygen-containing compound0.00093242.398e-05InformativeDirect
Biological Process (BP)positive regulation of transport0.00021420.08066InformativeInherited
Biological Process (BP)nitrogen compound transport0.0086050.1316InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression1.277e-060.03551InformativeInherited
Biological Process (BP)monocarboxylic acid biosynthetic process0.65940.2437InformativeInherited
Biological Process (BP)organic hydroxy compound biosynthetic process0.022650.338InformativeInherited
Biological Process (BP)regulation of ion transport3.84e-050.009653InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process9.689e-060.05445InformativeInherited
Biological Process (BP)coenzyme biosynthetic process0.013440.05691InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.0025170InformativeInherited
Biological Process (BP)vitamin metabolic process0.015380.0455InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.076190.4011InformativeInherited
Biological Process (BP)single-organism behavior2.513e-050.09092InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.18850.9128InformativeInherited
Biological Process (BP)transmission of nerve impulse5.342e-050.2684InformativeInherited
Biological Process (BP)cell-cell signaling0.0004170.524InformativeInherited
Biological Process (BP)regulation of neurotransmitter levels8.801e-077.817e-05Highly InformativeDirect
Biological Process (BP)lactate metabolic process2.555e-064.331e-08Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process3.138e-072.798e-07Highly InformativeDirect
Biological Process (BP)neurotransmitter transport6.605e-086.118e-05Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process5.822e-083.214e-12Highly InformativeDirect
Biological Process (BP)regulation of proton transport1.215e-117.39e-10Highly InformativeDirect
Biological Process (BP)monoamine transport5.547e-118.634e-10Highly InformativeDirect
Biological Process (BP)organic hydroxy compound transport1.574e-076.025e-06Highly InformativeDirect
Biological Process (BP)adult behavior2.096e-090.0001425Highly InformativeDirect
Biological Process (BP)regulation of protein stability8.262e-098.299e-07Highly InformativeDirect
Biological Process (BP)regulation of transporter activity6.539e-101.362e-06Highly InformativeDirect
Biological Process (BP)cellular response to reactive oxygen species6.86e-078.138e-12Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transport6.605e-082.13e-05Highly InformativeDirect
Biological Process (BP)cellular biogenic amine biosynthetic process2.027e-053.268e-08Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process3.2e-083.661e-10Highly InformativeDirect
Biological Process (BP)response to hydrogen peroxide3.407e-132.933e-09Highly InformativeDirect
Biological Process (BP)pteridine-containing compound biosynthetic process1.123e-062.968e-05Highly InformativeDirect
Biological Process (BP)thiamine-containing compound metabolic process6.681e-064.262e-05Highly InformativeDirect
Biological Process (BP)hydrogen peroxide metabolic process1.991e-075.062e-08Highly InformativeDirect
Biological Process (BP)regulation of neuron apoptotic process5.532e-060.0001043Highly InformativeDirect
Biological Process (BP)regulation of binding5.33e-070.0007061Highly InformativeDirect
Biological Process (BP)regulation of membrane potential0.00010650.01338Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.013480.1307Highly InformativeInherited
Biological Process (BP)pyrimidine-containing compound biosynthetic process0.0021980Highly InformativeInherited
Biological Process (BP)locomotory behavior1.162e-070.001239Highly InformativeInherited
Biological Process (BP)tryptophan metabolic process0.0021070.0007732Highly InformativeInherited
Molecular Function (MF)hydrolase activity0.59531Least InformativeInherited
Molecular Function (MF)oxidoreductase activity0.1350.6538Moderately InformativeInherited
Molecular Function (MF)lyase activity0.00038880.001981Moderately InformativeInherited
Molecular Function (MF)peptidase activity7.882e-081.215e-09InformativeDirect
Molecular Function (MF)carbon-carbon lyase activity8.782e-058.857e-08InformativeDirect
Molecular Function (MF)peroxidase activity1.114e-060Highly InformativeDirect
Molecular Function (MF)transaminase activity6.414e-051.38e-07Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity5.892e-120Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge7.162e-050.03577Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 2.533e-11 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 1.217e-10 Least Informative Direct
Biological Process (BP) biosynthetic process 1.605e-14 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 3.094e-10 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 7.116e-11 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 1.876e-10 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 1.669e-06 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.0008228 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 0.244 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.01456 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of programmed cell death 0.6033 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.003711 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) ion transport 0.8789 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.9409 Moderately Informative Inherited
Biological Process (BP) sulfur compound metabolic process 0.03481 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.002726 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.03499 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.0024 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.07014 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.2956 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 8.593e-14 Informative Direct
Biological Process (BP) response to oxidative stress 5.721e-14 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 8.756e-10 Informative Direct
Biological Process (BP) response to inorganic substance 7.432e-08 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0 Informative Direct
Biological Process (BP) pyrimidine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 9.25e-06 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 2.398e-05 Informative Direct
Biological Process (BP) positive regulation of transport 0.08066 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.1316 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 1 Informative Inherited
Biological Process (BP) purine ribonucleoside metabolic process 1 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.03551 Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.2506 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.338 Informative Inherited
Biological Process (BP) regulation of ion transport 0.009653 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.05445 Informative Inherited
Biological Process (BP) coenzyme biosynthetic process 0.05691 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.0455 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.4011 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 1 Informative Inherited
Biological Process (BP) nucleoside monophosphate metabolic process 0.7905 Informative Inherited
Biological Process (BP) single-organism behavior 0.09092 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.2437 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.9128 Informative Inherited
Biological Process (BP) transmission of nerve impulse 0.2684 Informative Inherited
Biological Process (BP) cell-cell signaling 0.524 Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 7.817e-05 Highly Informative Direct
Biological Process (BP) lactate metabolic process 4.331e-08 Highly Informative Direct
Biological Process (BP) pyrimidine nucleotide metabolic process 2.057e-08 Highly Informative Direct
Biological Process (BP) tryptophan metabolic process 0.0007732 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 2.798e-07 Highly Informative Direct
Biological Process (BP) neurotransmitter transport 6.118e-05 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 3.214e-12 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 7.504e-11 Highly Informative Direct
Biological Process (BP) nucleoside monophosphate biosynthetic process 0.0006672 Highly Informative Direct
Biological Process (BP) regulation of proton transport 7.39e-10 Highly Informative Direct
Biological Process (BP) monoamine transport 8.634e-10 Highly Informative Direct
Biological Process (BP) organic hydroxy compound transport 6.025e-06 Highly Informative Direct
Biological Process (BP) adult behavior 0.0001425 Highly Informative Direct
Biological Process (BP) regulation of protein stability 8.299e-07 Highly Informative Direct
Biological Process (BP) regulation of transporter activity 1.362e-06 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 8.138e-12 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transport 2.13e-05 Highly Informative Direct
Biological Process (BP) cellular biogenic amine biosynthetic process 3.268e-08 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 3.661e-10 Highly Informative Direct
Biological Process (BP) response to hydrogen peroxide 2.933e-09 Highly Informative Direct
Biological Process (BP) pteridine-containing compound biosynthetic process 2.968e-05 Highly Informative Direct
Biological Process (BP) thiamine-containing compound metabolic process 4.262e-05 Highly Informative Direct
Biological Process (BP) hydrogen peroxide metabolic process 5.062e-08 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 0.0001043 Highly Informative Direct
Biological Process (BP) pyrimidine ribonucleoside metabolic process 1.086e-08 Highly Informative Direct
Biological Process (BP) regulation of binding 0.0007061 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 5.229e-05 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 0.01338 Highly Informative Inherited
Biological Process (BP) benzene-containing compound metabolic process 0.03309 Highly Informative Inherited
Biological Process (BP) guanosine-containing compound metabolic process 0.006743 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.1307 Highly Informative Inherited
Biological Process (BP) locomotory behavior 0.001239 Highly Informative Inherited
Biological Process (BP) amide biosynthetic process 0.6632 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0.6538 Moderately Informative Inherited
Molecular Function (MF) lyase activity 0.001981 Moderately Informative Inherited
Molecular Function (MF) peptidase activity 1.215e-09 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.0003697 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 8.857e-08 Informative Direct
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 0 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.003261 Informative Inherited
Molecular Function (MF) peroxidase activity 0 Highly Informative Direct
Molecular Function (MF) exopeptidase activity 5.588e-07 Highly Informative Direct
Molecular Function (MF) transaminase activity 1.38e-07 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.0003899 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.03577 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9975Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2799Moderately InformativeInherited
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0.8592Moderately InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases7.861e-09InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Peroxidases0.165InformativeInherited
Enzyme Commission (EC)GMP synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Anthranilate synthase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)locomotion variant0.0001427Moderately InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)fertile0Least InformativeDirect
Fly Phenotype (FP)increased mortality0Least InformativeDirect
Fly Phenotype (FP)male fertile0.0004333InformativeDirect
Fly Phenotype (FP)auxotroph2.46e-10Highly InformativeDirect
Fly Phenotype (FP)female fertile0.0008458Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-carbon lyases0.251Moderately InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.8823Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N-donor0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.0001373InformativeDirect
Enzyme Commission (EC)Omega peptidases0.1351InformativeInherited
Enzyme Commission (EC)Acting on a peroxide as acceptor0.1509InformativeInherited
Enzyme Commission (EC)Hexosyltransferases1InformativeInherited
Enzyme Commission (EC)In linear amides1InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0Highly InformativeDirect
Enzyme Commission (EC)Metallocarboxypeptidases0.002229Highly InformativeInherited
Enzyme Commission (EC)Peroxidases0.1449Highly InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processFertilization1.027e-05Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationTransferase0.03019Least InformativeInherited
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationProtease0.01179Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationSerine protease1.345e-14InformativeDirect
Post-translational modificationCarboxypeptidase0.0003429Highly InformativeDirect
Post-translational modificationOxidation7.663e-05Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism2.146e-16Least InformativeDirect
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)L-arginine metabolism0Moderately InformativeDirect
UniPathway (UP)heterocycle metabolism0Moderately InformativeDirect
UniPathway (UP)macrocycle metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis0.1274Moderately InformativeInherited
UniPathway (UP)aromatic compound biosynthesis1Moderately InformativeInherited
UniPathway (UP)L-arginine biosynthesis0InformativeDirect
UniPathway (UP)adenosylcobalamin biosynthesis0InformativeDirect
UniPathway (UP)aromatic amino-acid biosynthesis0.0002232InformativeDirect
UniPathway (UP)pyrimidine biosynthesis1InformativeInherited
UniPathway (UP)purine biosynthesis1InformativeInherited
UniPathway (UP)GMP biosynthesis0Highly InformativeDirect
UniPathway (UP)L-tryptophan biosynthesis3.91e-06Highly InformativeDirect

Document: UP annotation of SCOP domains

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 35 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]