SUPERFAMILY 1.75 HMM library and genome assignments server


Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  A4 beta-galactosidase middle domain [ 82351]
  DJ-1/PfpI [ 52325] (9)
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  ThuA-like [ 110486]
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  HTS-like [ 142077]
  STM3548-like [ 159492]


Superfamily statistics
Genomes (2,490) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 37,412 113,729 68
Proteins 36,988 113,381 68


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of cellular process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.055282.197e-10Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.57111Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.10134.008e-15Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.021996.165e-09Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.019115.478e-09Least InformativeInherited
Biological Process (BP)biosynthetic process0.012552.131e-13Least InformativeInherited
Biological Process (BP)response to stimulus0.65111Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.12864.672e-11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.00021390Moderately InformativeDirect
Biological Process (BP)heterocycle biosynthetic process7.043e-070Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process1.105e-073.682e-14Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process2.051e-050Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process4.244e-060Moderately InformativeDirect
Biological Process (BP)organonitrogen compound biosynthetic process2.917e-050Moderately InformativeDirect
Biological Process (BP)cellular response to chemical stimulus3.102e-060.05025Moderately InformativeInherited
Biological Process (BP)homeostatic process0.4190.8191Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.071531Moderately InformativeInherited
Biological Process (BP)regulation of response to stimulus0.46961Moderately InformativeInherited
Biological Process (BP)regulation of molecular function0.027260.8204Moderately InformativeInherited
Biological Process (BP)small molecule biosynthetic process4.874e-060.06214Moderately InformativeInherited
Biological Process (BP)cellular response to stress1.424e-060.009637Moderately InformativeInherited
Biological Process (BP)regulation of localization0.038310.9675Moderately InformativeInherited
Biological Process (BP)ion transport0.031080.6591Moderately InformativeInherited
Biological Process (BP)organic substance transport0.099230.8191Moderately InformativeInherited
Biological Process (BP)system process0.026511Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0032970.003531Moderately InformativeInherited
Biological Process (BP)cellular biogenic amine metabolic process2.387e-073.161e-09InformativeDirect
Biological Process (BP)response to oxidative stress3.099e-158.676e-14InformativeDirect
Biological Process (BP)amine biosynthetic process6.483e-063.022e-05InformativeDirect
Biological Process (BP)response to inorganic substance6.264e-061.653e-07InformativeDirect
Biological Process (BP)pyrimidine-containing compound metabolic process0.00036480InformativeDirect
Biological Process (BP)cellular response to oxygen-containing compound0.0003560.0002772InformativeDirect
Biological Process (BP)positive regulation of transport4.474e-050.03555InformativeInherited
Biological Process (BP)nitrogen compound transport0.00450.09217InformativeInherited
Biological Process (BP)negative regulation of molecular function0.01380.13InformativeInherited
Biological Process (BP)regulation of response to external stimulus0.00040170.0523InformativeInherited
Biological Process (BP)regulation of response to stress0.0062470.3064InformativeInherited
Biological Process (BP)regulation of apoptotic process0.0007980.3646InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression3.355e-070.01514InformativeInherited
Biological Process (BP)regulation of ion transport8e-060.002773InformativeInherited
Biological Process (BP)vitamin metabolic process0.0029210.01358InformativeInherited
Biological Process (BP)sulfur compound biosynthetic process0.029720.2117InformativeInherited
Biological Process (BP)single-organism behavior6.359e-060.04712InformativeInherited
Biological Process (BP)synaptic transmission7.052e-060.1025InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.0034690.3311InformativeInherited
Biological Process (BP)regulation of neurotransmitter levels1.352e-065.28e-05Highly InformativeDirect
Biological Process (BP)neurotransmitter transport5.024e-084.347e-05Highly InformativeDirect
Biological Process (BP)locomotory behavior2.68e-080.0005983Highly InformativeDirect
Biological Process (BP)aromatic amino acid family biosynthetic process8.191e-103.287e-08Highly InformativeDirect
Biological Process (BP)regulation of proton transport7.201e-125.497e-10Highly InformativeDirect
Biological Process (BP)monoamine transport2.697e-114.686e-10Highly InformativeDirect
Biological Process (BP)organic hydroxy compound transport3.518e-082.083e-06Highly InformativeDirect
Biological Process (BP)adult behavior1.082e-098.747e-05Highly InformativeDirect
Biological Process (BP)regulation of protein stability7.565e-092.328e-07Highly InformativeDirect
Biological Process (BP)cellular response to reactive oxygen species2.368e-075.751e-11Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transport8.07e-093.272e-06Highly InformativeDirect
Biological Process (BP)cellular biogenic amine biosynthetic process8.646e-073.801e-06Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process2.433e-092.618e-07Highly InformativeDirect
Biological Process (BP)response to hydrogen peroxide5.676e-091.125e-07Highly InformativeDirect
Biological Process (BP)hydrogen peroxide metabolic process7.124e-082.671e-08Highly InformativeDirect
Biological Process (BP)regulation of neuron apoptotic process4.841e-064.713e-05Highly InformativeDirect
Biological Process (BP)regulation of inflammatory response7.4e-060.0008436Highly InformativeDirect
Biological Process (BP)regulation of binding1.856e-060.0004571Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound biosynthetic process0.00067150Highly InformativeDirect
Biological Process (BP)regulation of membrane potential0.00066430.006318Highly InformativeInherited
Biological Process (BP)tryptophan metabolic process9.827e-050.004473Highly InformativeInherited
Molecular Function (MF)hydrolase activity0.34360.8053Least InformativeInherited
Molecular Function (MF)oxidoreductase activity0.091860.6693Moderately InformativeInherited
Molecular Function (MF)lyase activity3.262e-050.002078Moderately InformativeInherited
Molecular Function (MF)peptidase activity2.251e-092.44e-11InformativeDirect
Molecular Function (MF)ligase activity, forming carbon-nitrogen bonds0.02090InformativeInherited
Molecular Function (MF)carbon-carbon lyase activity0.0055760.0002422InformativeInherited
Molecular Function (MF)peroxidase activity6.17e-071.341e-12Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity8.813e-113.07e-15Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge7.456e-050.01264Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 6.165e-09 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 4.672e-11 Least Informative Direct
Biological Process (BP) biosynthetic process 2.131e-13 Least Informative Direct
Biological Process (BP) single-organism metabolic process 4.008e-15 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 5.478e-09 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 2.197e-10 Least Informative Direct
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 3.682e-14 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 1.787e-07 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 2.204e-12 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 2.398e-06 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organonitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.05025 Moderately Informative Inherited
Biological Process (BP) homeostatic process 0.8191 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.8204 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.06214 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.009637 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.9675 Moderately Informative Inherited
Biological Process (BP) ion transport 0.6591 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.8191 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.2356 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.001832 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.003531 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 3.161e-09 Informative Direct
Biological Process (BP) response to oxidative stress 8.676e-14 Informative Direct
Biological Process (BP) glutamine family amino acid metabolic process 0.0004796 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 3.197e-07 Informative Direct
Biological Process (BP) amine biosynthetic process 3.022e-05 Informative Direct
Biological Process (BP) response to inorganic substance 1.653e-07 Informative Direct
Biological Process (BP) ribose phosphate metabolic process 1.014e-08 Informative Direct
Biological Process (BP) pyrimidine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 5.178e-06 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.0002772 Informative Direct
Biological Process (BP) positive regulation of transport 0.03555 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.09217 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.13 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.0523 Informative Inherited
Biological Process (BP) regulation of response to stress 0.3064 Informative Inherited
Biological Process (BP) ribonucleoside metabolic process 0.8136 Informative Inherited
Biological Process (BP) purine nucleotide metabolic process 0.9893 Informative Inherited
Biological Process (BP) purine nucleoside metabolic process 1 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.3646 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.01514 Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.1175 Informative Inherited
Biological Process (BP) regulation of ion transport 0.002773 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.01358 Informative Inherited
Biological Process (BP) sulfur compound biosynthetic process 0.2117 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.04712 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 1 Informative Inherited
Biological Process (BP) synaptic transmission 0.1025 Informative Inherited
Biological Process (BP) alpha-amino acid biosynthetic process 0.3311 Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 5.28e-05 Highly Informative Direct
Biological Process (BP) pyrimidine nucleotide metabolic process 2.077e-06 Highly Informative Direct
Biological Process (BP) neurotransmitter transport 4.347e-05 Highly Informative Direct
Biological Process (BP) locomotory behavior 0.0005983 Highly Informative Direct
Biological Process (BP) aromatic amino acid family biosynthetic process 3.287e-08 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 1.566e-10 Highly Informative Direct
Biological Process (BP) nucleoside monophosphate metabolic process 2.221e-06 Highly Informative Direct
Biological Process (BP) nucleoside triphosphate biosynthetic process 0.0006766 Highly Informative Direct
Biological Process (BP) regulation of proton transport 5.497e-10 Highly Informative Direct
Biological Process (BP) monoamine transport 4.686e-10 Highly Informative Direct
Biological Process (BP) organic hydroxy compound transport 2.083e-06 Highly Informative Direct
Biological Process (BP) adult behavior 8.747e-05 Highly Informative Direct
Biological Process (BP) regulation of protein stability 2.328e-07 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 5.751e-11 Highly Informative Direct
Biological Process (BP) regulation of transmembrane transport 3.272e-06 Highly Informative Direct
Biological Process (BP) cellular biogenic amine biosynthetic process 3.801e-06 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 2.618e-07 Highly Informative Direct
Biological Process (BP) response to hydrogen peroxide 1.125e-07 Highly Informative Direct
Biological Process (BP) pteridine-containing compound metabolic process 1.255e-05 Highly Informative Direct
Biological Process (BP) hydrogen peroxide metabolic process 2.671e-08 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 4.713e-05 Highly Informative Direct
Biological Process (BP) regulation of inflammatory response 0.0008436 Highly Informative Direct
Biological Process (BP) regulation of binding 0.0004571 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound biosynthetic process 0 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 0.006318 Highly Informative Inherited
Biological Process (BP) pyrimidine nucleoside metabolic process 0.001331 Highly Informative Inherited
Biological Process (BP) guanosine-containing compound metabolic process 0.00504 Highly Informative Inherited
Biological Process (BP) tryptophan metabolic process 0.004473 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0.8053 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0.6693 Moderately Informative Inherited
Molecular Function (MF) lyase activity 0.002078 Moderately Informative Inherited
Molecular Function (MF) peptidase activity 2.44e-11 Informative Direct
Molecular Function (MF) transferase activity, transferring one-carbon groups 0.000721 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0.0002422 Informative Direct
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 0 Informative Direct
Molecular Function (MF) peroxidase activity 1.341e-12 Highly Informative Direct
Molecular Function (MF) exopeptidase activity 1.077e-07 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 3.07e-15 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0.01264 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9975Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Omega peptidases0.2799Moderately InformativeInherited
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0.8592Moderately InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases7.861e-09InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Peroxidases0.165InformativeInherited
Enzyme Commission (EC)GMP synthase (glutamine-hydrolyzing)0Highly InformativeDirect
Enzyme Commission (EC)Anthranilate synthase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)locomotion variant0.0001427Moderately InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)fertile0Least InformativeDirect
Fly Phenotype (FP)male fertile0.0003217InformativeDirect
Fly Phenotype (FP)auxotroph1.941e-10Highly InformativeDirect
Fly Phenotype (FP)female fertile0.0006629Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Carbon-carbon lyases0.4441Moderately InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.9653Moderately InformativeInherited
Enzyme Commission (EC)Glycosylases1Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-oxygen lyases1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Other carbon--nitrogen ligases0.001691InformativeInherited
Enzyme Commission (EC)Acting on a peroxide as acceptor0.1552InformativeInherited
Enzyme Commission (EC)Omega peptidases0.3127InformativeInherited
Enzyme Commission (EC)In linear amides1InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases1InformativeInherited
Enzyme Commission (EC)Beta-galactosidase0Highly InformativeDirect
Enzyme Commission (EC)Dipeptidases0Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0Highly InformativeDirect
Enzyme Commission (EC)Metallocarboxypeptidases0.002188Highly InformativeInherited
Enzyme Commission (EC)Peroxidases0.1492Highly InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1Highly InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processPurine biosynthesis0InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processCobalamin biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processFertilization4.582e-06Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
Cellular componentVirion1InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationTransferase0.06475Least InformativeInherited
Post-translational modificationHydrolase1Least InformativeInherited
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationProtease0.008939Moderately InformativeInherited
Post-translational modificationOxidoreductase1Moderately InformativeInherited
Post-translational modificationAcyltransferase0InformativeDirect
Post-translational modificationSerine protease1.363e-14InformativeDirect
Post-translational modificationCarboxypeptidase0.0003891Highly InformativeDirect
Post-translational modificationPeroxidase0.02326Highly InformativeInherited
Post-translational modificationOxidation1.298e-07Highly InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0Least InformativeDirect
UniPathway (UP)cofactor metabolism1Least InformativeInherited
UniPathway (UP)amino-acid metabolism1Least InformativeInherited
UniPathway (UP)proteinogenic amino-acid biosynthesis0Moderately InformativeDirect
UniPathway (UP)purine metabolism0Moderately InformativeDirect
UniPathway (UP)nucleotide metabolism6.497e-10Moderately InformativeDirect
UniPathway (UP)UMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)IMP biosynthesis via de novo pathway0InformativeDirect
UniPathway (UP)nucleotide biosynthesis0InformativeDirect
UniPathway (UP)histidine metabolism0InformativeDirect
UniPathway (UP)L-methionine biosynthesis0InformativeDirect
UniPathway (UP)L-arginine biosynthesis5.199e-14InformativeDirect
UniPathway (UP)adenosylcobalamin biosynthesis0Highly InformativeDirect
UniPathway (UP)GMP biosynthesis0Highly InformativeDirect
UniPathway (UP)CTP biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 35 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]