SUPERFAMILY 1.75 HMM library and genome assignments server


Beta-D-glucan exohydrolase, C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Beta-D-glucan exohydrolase, C-terminal domain [ 52279]
Families:   Beta-D-glucan exohydrolase, C-terminal domain [ 52280]


Superfamily statistics
Genomes (1,321) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 5,487 15,832 2
Proteins 5,462 15,789 2


Functional annotation
General category Metabolism
Detailed category Carbohydrate metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.9067 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 2.108e-10 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 1.767e-05 Moderately Informative Direct
Biological Process (BP) polysaccharide metabolic process 1.544e-11 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0 Informative Direct
Biological Process (BP) polysaccharide catabolic process 6.256e-11 Highly Informative Direct
Biological Process (BP) cell wall macromolecule metabolic process 7.916e-12 Highly Informative Direct
Molecular Function (MF) hydrolase activity 5.818e-09 Least Informative Direct
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0 Informative Direct
Cellular Component (CC) external encapsulating structure 3.516e-06 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0Moderately InformativeDirect
Enzyme Commission (EC)Beta-glucosidase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)leaf0.3707Least InformativeInherited
Plant ANatomical entity (PAN)fruit0.0007994InformativeDirect
Plant ANatomical entity (PAN)adult vascular leaf1.74e-09Highly InformativeDirect
Plant ANatomical entity (PAN)juvenile vascular leaf1.74e-09Highly InformativeDirect
Plant ANatomical entity (PAN)plant ovule0.0001667Highly InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Glycosylases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processPolysaccharide degradation0InformativeDirect
Biological processCellulose degradation0Highly InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentPeriplasm0.0008165InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane1Least InformativeInherited
DomainSignal-anchor0.0003331InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationGlycosidase0InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)glycan degradation0InformativeDirect
UniPathway (UP)cellulose metabolism0InformativeDirect
UniPathway (UP)cellulose degradation0Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR002772 SSF52279 Protein matches
Abstract

Glycoside hydrolase family 3 comprises enzymes with a number of known activities; beta-glucosidase ; beta-xylosidase ; N-acetyl beta-glucosaminidase ; glucan beta-1,3-glucosidase ; cellodextrinase; exo-1,3-1,4-glucanase .

These enzymes are two-domain globular proteins that are N-glycosylated at three sites [PubMed10368285]. This domain is often C-terminal to the glycoside hydrolase family 3, N terminal domain .


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Beta-D-glucan exohydrolase, C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Beta-D-glucan exohydrolase, C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]