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RNI-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [ 52046] (3)
Superfamily:   RNI-like [ 52047] (3)
Families:   28-residue LRR [ 52048] (2)
  Rna1p (RanGAP1), N-terminal domain [ 52052]
  Cyclin A/CDK2-associated p19, Skp2 [ 52055]


Superfamily statistics
Genomes (820) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 63,448 57,411 12
Proteins 57,316 52,483 9


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.91851Least InformativeInherited
Biological Process (BP)response to stimulus10.1931Least InformativeInherited
Biological Process (BP)protein metabolic process0.57680.4939Least InformativeInherited
Biological Process (BP)cellular catabolic process0.31290.1802Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.49770.2753Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.15981Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.54680.3614Moderately InformativeInherited
Biological Process (BP)protein catabolic process0.000045910InformativeDirect
Biological Process (BP)proteolysis0.00017630.0000000005967InformativeDirect
Biological Process (BP)cellular macromolecule catabolic process0.00045270.00000000008913InformativeDirect
Biological Process (BP)response to light stimulus0.0074660.01412InformativeInherited
Biological Process (BP)protein modification by small protein conjugation or removal0.0046650.00000000000004613InformativeInherited
Biological Process (BP)ubiquitin-dependent protein catabolic process0.0000042190Highly InformativeDirect
Biological Process (BP)regulation of circadian rhythm0.0000085080.0000001125Highly InformativeDirect
Biological Process (BP)protein ubiquitination0.00037160Highly InformativeDirect
Molecular Function (MF)ligase activity0.001090.00000005238InformativeInherited
Molecular Function (MF)small conjugating protein ligase activity0.000031210Highly InformativeDirect
Cellular Component (CC)protein complex10.00144Least InformativeInherited
Cellular Component (CC)ubiquitin ligase complex0.00043410InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.1931 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.4939 Least Informative Inherited
Biological Process (BP) response to organic substance 0 Moderately Informative Direct
Biological Process (BP) response to endogenous stimulus 0 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.000000000000003755 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.0000004629 Moderately Informative Direct
Biological Process (BP) immune system process 0.0000004874 Moderately Informative Direct
Biological Process (BP) signal transduction 0.000005639 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.434 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.3614 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.6972 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.6279 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.3758 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.1802 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.2753 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.6584 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.4951 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 0.001387 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.816 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.3312 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) protein catabolic process 0 Informative Direct
Biological Process (BP) proteolysis 0.0000000005967 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 0.00000000008913 Informative Direct
Biological Process (BP) protein modification by small protein conjugation or removal 0.00000000000004613 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) regulation of defense response 0.000000000000003755 Informative Direct
Biological Process (BP) regulation of cytokine production 0.00000000000002119 Informative Direct
Biological Process (BP) response to bacterium 0.0000000000001114 Informative Direct
Biological Process (BP) reproductive system development 0.0000000001607 Informative Direct
Biological Process (BP) immune response 0.000000003554 Informative Direct
Biological Process (BP) regulation of immune response 0.000000003597 Informative Direct
Biological Process (BP) positive regulation of immune system process 0.000001232 Informative Direct
Biological Process (BP) cellular response to endogenous stimulus 0.000004041 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0.00001889 Informative Direct
Biological Process (BP) developmental process involved in reproduction 0.00003538 Informative Direct
Biological Process (BP) regulation of protein localization 0.0000466 Informative Direct
Biological Process (BP) response to hormone stimulus 0.00008182 Informative Direct
Biological Process (BP) regulation of secretion 0.0005403 Informative Direct
Biological Process (BP) positive regulation of transport 0.0007033 Informative Direct
Biological Process (BP) regulation of peptidase activity 0.00216 Informative Inherited
Biological Process (BP) regulation of cellular component movement 0.3154 Informative Inherited
Biological Process (BP) regulation of locomotion 0.6819 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.01594 Informative Inherited
Biological Process (BP) response to organic cyclic compound 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.5937 Informative Inherited
Biological Process (BP) response to organonitrogen compound 1 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 0.8734 Informative Inherited
Biological Process (BP) cation homeostasis 0.663 Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0.8169 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 1 Informative Inherited
Biological Process (BP) growth 1 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) regulation of growth 0.5284 Informative Inherited
Biological Process (BP) apoptotic process 1 Informative Inherited
Biological Process (BP) response to light stimulus 0.01412 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of protein metabolic process 0.2388 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.0751 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.08006 Informative Inherited
Biological Process (BP) negative regulation of immune system process 0.02081 Informative Inherited
Biological Process (BP) regulation of intracellular protein kinase cascade 0.01789 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.2814 Informative Inherited
Biological Process (BP) response to lipid 0.1826 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 1 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.377 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of immune effector process 0.7736 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.02195 Informative Inherited
Biological Process (BP) immune effector process 0.7031 Informative Inherited
Biological Process (BP) leukocyte activation 1 Informative Inherited
Biological Process (BP) cell cycle process 0.1796 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.005297 Informative Inherited
Biological Process (BP) ubiquitin-dependent protein catabolic process 0 Highly Informative Direct
Biological Process (BP) regulation of circadian rhythm 0.0000001125 Highly Informative Direct
Biological Process (BP) protein ubiquitination 0 Highly Informative Direct
Biological Process (BP) post-embryonic organ development 0 Highly Informative Direct
Biological Process (BP) hormone-mediated signaling pathway 0 Highly Informative Direct
Biological Process (BP) positive regulation of protein secretion 0.0000000000259 Highly Informative Direct
Biological Process (BP) positive regulation of cytokine production 0.00000000004421 Highly Informative Direct
Biological Process (BP) post-embryonic development 0.000000000159 Highly Informative Direct
Biological Process (BP) regulation of toll-like receptor signaling pathway 0.0000000006124 Highly Informative Direct
Biological Process (BP) positive regulation of defense response 0.000000004708 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 0.00000004166 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0.000001316 Highly Informative Direct
Biological Process (BP) cellular response to biotic stimulus 0.000001788 Highly Informative Direct
Biological Process (BP) myeloid leukocyte activation 0.00000181 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.000002111 Highly Informative Direct
Biological Process (BP) positive regulation of sequence-specific DNA binding transcription factor activity 0.000005939 Highly Informative Direct
Biological Process (BP) negative regulation of sequence-specific DNA binding transcription factor activity 0.00001047 Highly Informative Direct
Biological Process (BP) regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.00001275 Highly Informative Direct
Biological Process (BP) regulation of protein ubiquitination 0.00001407 Highly Informative Direct
Biological Process (BP) regulation of production of molecular mediator of immune response 0.00007694 Highly Informative Direct
Biological Process (BP) regulation of cytokine secretion 0.000184 Highly Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.0008202 Highly Informative Direct
Biological Process (BP) response to lipopolysaccharide 0.0009986 Highly Informative Direct
Biological Process (BP) regulation of behavior 0.6548 Highly Informative Inherited
Biological Process (BP) cellular response to steroid hormone stimulus 0.001205 Highly Informative Inherited
Biological Process (BP) cellular response to peptide 1 Highly Informative Inherited
Biological Process (BP) transition metal ion homeostasis 0.001047 Highly Informative Inherited
Biological Process (BP) regulation of endocytosis 0.2638 Highly Informative Inherited
Biological Process (BP) regulation of interleukin-1 beta production 0.7328 Highly Informative Inherited
Biological Process (BP) cell growth 0.1225 Highly Informative Inherited
Biological Process (BP) developmental growth 0.9704 Highly Informative Inherited
Biological Process (BP) epidermal cell differentiation 1 Highly Informative Inherited
Biological Process (BP) DNA replication 0.4058 Highly Informative Inherited
Biological Process (BP) regulation of multi-organism process 0.07265 Highly Informative Inherited
Biological Process (BP) response to UV 0.6544 Highly Informative Inherited
Biological Process (BP) positive regulation of endopeptidase activity 0.02853 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to stress 0.06288 Highly Informative Inherited
Biological Process (BP) positive regulation of MAPK cascade 0.7176 Highly Informative Inherited
Biological Process (BP) proteasomal protein catabolic process 0.04978 Highly Informative Inherited
Biological Process (BP) regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.0089 Highly Informative Inherited
Biological Process (BP) ossification 0.001807 Highly Informative Inherited
Biological Process (BP) regulation of developmental growth 0.2126 Highly Informative Inherited
Biological Process (BP) regulation of adaptive immune response based on somatic recombination of immune receptors built from 0.06787 Highly Informative Inherited
Biological Process (BP) negative regulation of response to external stimulus 0.03862 Highly Informative Inherited
Biological Process (BP) negative regulation of immune response 0.006799 Highly Informative Inherited
Biological Process (BP) regulation of humoral immune response 0.3031 Highly Informative Inherited
Biological Process (BP) immune response-activating signal transduction 0.07326 Highly Informative Inherited
Biological Process (BP) positive regulation of lymphocyte mediated immunity 0.09217 Highly Informative Inherited
Biological Process (BP) positive regulation of adaptive immune response 0.4844 Highly Informative Inherited
Biological Process (BP) negative regulation of immune effector process 0.2244 Highly Informative Inherited
Biological Process (BP) leukocyte mediated immunity 0.8508 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) anion binding 0.0002991 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 1 Moderately Informative Inherited
Molecular Function (MF) cation binding 1 Moderately Informative Inherited
Molecular Function (MF) ligase activity 0.00000005238 Informative Direct
Molecular Function (MF) amide binding 0.000003493 Informative Direct
Molecular Function (MF) lipid binding 0.6164 Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.1642 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 0.09174 Informative Inherited
Molecular Function (MF) receptor activity 0.3542 Informative Inherited
Molecular Function (MF) molecular transducer activity 0.5439 Informative Inherited
Molecular Function (MF) small conjugating protein ligase activity 0 Highly Informative Direct
Molecular Function (MF) alcohol binding 0 Highly Informative Direct
Molecular Function (MF) peptide binding 0.000001507 Highly Informative Direct
Molecular Function (MF) hormone binding 0.00001284 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase regulator activity involved in apoptotic process 0.00003967 Highly Informative Direct
Molecular Function (MF) iron ion binding 0.0003725 Highly Informative Direct
Cellular Component (CC) protein complex 0.00144 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intrinsic to membrane 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) cytoskeleton 1 Moderately Informative Inherited
Cellular Component (CC) ubiquitin ligase complex 0 Informative Direct
Cellular Component (CC) integral to membrane 1 Informative Inherited
Cellular Component (CC) chromosome 1 Informative Inherited
Cellular Component (CC) contractile fiber part 0.5951 Informative Inherited
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) actin cytoskeleton 0.2796 Informative Inherited
Cellular Component (CC) cullin-RING ubiquitin ligase complex 0.000007655 Highly Informative Direct
Cellular Component (CC) receptor complex 0.0215 Highly Informative Inherited
Cellular Component (CC) nuclear chromosome part 0.5941 Highly Informative Inherited
Cellular Component (CC) cell body 0.341 Highly Informative Inherited
Cellular Component (CC) sarcomere 0.9864 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.4543Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0.0000000175Moderately InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0.000000000000002328Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)syndrome0.28Moderately InformativeInherited
Disease Ontology (DO)inflammatory bowel disease0.0001698InformativeDirect
Disease Ontology (DO)allergic rhinitis0.0004373InformativeDirect
Disease Ontology (DO)Crohn's disease0.000007943Highly InformativeDirect
Disease Ontology (DO)irritable bowel syndrome0.0002191Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.3502Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1614Moderately InformativeInherited
Phenotypic Abnormality (PA)Arthralgia0.0003084Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype0.08511Least InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.0002384Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal inflammatory response0.1796Moderately InformativeInherited
Mammalian Phenotype (MP)digestive/alimentary phenotype0.2634Moderately InformativeInherited
Mammalian Phenotype (MP)increased susceptibility to infection0.0005339InformativeDirect
Mammalian Phenotype (MP)abnormal digestive system physiology0.05449InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin secretion0.05663InformativeInherited
Mammalian Phenotype (MP)abnormal interferon secretion0.9614InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin-1 beta secretion0.00000006088Highly InformativeDirect
Mammalian Phenotype (MP)decreased interleukin-12b secretion0.000033Highly InformativeDirect
Mammalian Phenotype (MP)colitis0.0001004Highly InformativeDirect
Mammalian Phenotype (MP)abnormal tumor necrosis factor secretion0.5032Highly InformativeInherited
Mammalian Phenotype (MP)decreased susceptibility to infection0.5233Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.9966Least InformativeInherited
Worm Phenotype (WP)protein aggregation variant0.5472Moderately InformativeInherited
Worm Phenotype (WP)protein aggregation induced paralysis0.0003916InformativeDirect
Worm Phenotype (WP)resistant to protein aggregation induced paralysis0.0001317Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure1Least InformativeInherited
Plant ANatomical entity (PAN)sporangium1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)anther0.00008324Highly InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.5648Least InformativeInherited
Enzyme Commission (EC)Lyases0.7505Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0.00000005356InformativeDirect
Enzyme Commission (EC)Protein-tyrosine kinases0.011InformativeInherited
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0.0000000000000064Highly InformativeDirect
Enzyme Commission (EC)Adenylate cyclase0.00000000007918Highly InformativeDirect
Enzyme Commission (EC)Receptor protein-tyrosine kinase0.000004493Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processApoptosis0.000000000002164Moderately InformativeDirect
Biological processDifferentiation0.0001291Moderately InformativeDirect
Biological processCell cycle0.346Moderately InformativeInherited
Biological processInflammatory response0InformativeDirect
Biological processInnate immunity0InformativeDirect
Biological processPlant defense0InformativeDirect
Biological processUbl conjugation pathway0InformativeDirect
Biological processMitosis0.00000264InformativeDirect
Biological processBiological rhythms0.00001969InformativeDirect
Biological processAuxin signaling pathway0Highly InformativeDirect
Cellular componentNucleus0.0000000608Least InformativeDirect
Cellular componentCytoplasm1Least InformativeInherited
Cellular componentCytoskeleton0.00000000001584Moderately InformativeDirect
Cellular componentCell projection0.01077Moderately InformativeInherited
Cellular componentCilium0.007911Highly InformativeInherited
DomainRepeat0Least InformativeDirect
DomainLeucine-rich repeat0InformativeDirect
Molecular functionActin-binding0.000000001188InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationDevelopmental protein0.0000003976Moderately InformativeDirect
Post-translational modificationKinase0.0069Moderately InformativeInherited
Post-translational modificationOxidoreductase1Moderately InformativeInherited
Post-translational modificationSerine/threonine-protein kinase0InformativeDirect
Post-translational modificationGTPase activation0.00000003157InformativeDirect
Post-translational modificationDioxygenase0.0009619Highly InformativeDirect
Post-translational modificationPhosphoprotein0.000001447Least InformativeDirect
Post-translational modificationGlycoprotein0.000002455Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)protein ubiquitination0Moderately InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a RNI-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the RNI-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]