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Glycosyl hydrolases family 6, cellulases superfamily
SCOP classification
Superfamily statistics
Functional annotation
| General category | Metabolism |
| Detailed category | Polysaccharide metabolism and transport |
Function annotation of SCOP domain superfamilies
InterPro annotation
| Cross references | IPR001524 SSF51989 Protein matches |
| Abstract | Glycoside hydrolase family 6 comprises enzymes with several known activities; endoglucanase ; cellobiohydrolase . These enzymes were formerly known as cellulase family B.
The 3D structure of the enzymatic core of cellobiohydrolase II (CBHII) from
the fungus Trichoderma reesei reveals an alpha-beta protein with a fold
similar to the ubiquitous barrel topology first seen in triose phosphate
isomerase [ 2377893]. The active site of CBHII is located at the C-terminal end of
a parallel beta barrel, in an enclosed tunnel through which the cellulose
threads. Two aspartic acid residues, located in the centre of the tunnel
are the probable catalytic residues [2377893]. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]
Internal database links
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 5 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a Glycosyl hydrolases family 6, cellulases domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 5 hidden Markov models representing the Glycosyl hydrolases family 6, cellulases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]
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