SUPERFAMILY 1.75 HMM library and genome assignments server


Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,055) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 39,499 0 31
Proteins 39,102 0 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process1.197e-110Least InformativeDirect
Biological Process (BP)biosynthetic process0.031431Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.74431.231e-05Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.046641Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.62321Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.8581Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.028521Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.0001075Least InformativeInherited
Biological Process (BP)protein metabolic process11.053e-10Least InformativeInherited
Biological Process (BP)response to stimulus0.084451Least InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.00049710.02565Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.035342.164e-11Moderately InformativeInherited
Biological Process (BP)cell differentiation11Moderately InformativeInherited
Biological Process (BP)single-organism developmental process11Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.37081Moderately InformativeInherited
Biological Process (BP)organic substance transport0.78861Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.63121Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process11Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.036530.008727Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus1.059e-050.1188Moderately InformativeInherited
Biological Process (BP)oxidation-reduction process0.00076540.6898Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.06931Moderately InformativeInherited
Biological Process (BP)immune system process0.92691Moderately InformativeInherited
Biological Process (BP)homeostatic process0.22171Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)ion transport0.24451Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.00051140.1975Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.015120.1715Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.23760.4688Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process2.214e-050.283Moderately InformativeInherited
Biological Process (BP)cellular localization0.85431Moderately InformativeInherited
Biological Process (BP)cellular response to stress5.374e-050.1865Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process1.181e-111.558e-11InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process4.071e-082.421e-10InformativeDirect
Biological Process (BP)nitrogen compound transport0.0053530.2148InformativeInherited
Biological Process (BP)vesicle-mediated transport11InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.010610.009538InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.24530.4158InformativeInherited
Biological Process (BP)RNA modification9.618e-060.01091InformativeInherited
Biological Process (BP)DNA metabolic process0.0022221InformativeInherited
Biological Process (BP)leukocyte activation0.035320.4059InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.080230.5308InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.4861InformativeInherited
Biological Process (BP)anion transport0.73670.988InformativeInherited
Biological Process (BP)response to inorganic substance0.04570.456InformativeInherited
Biological Process (BP)cytoplasmic transport0.12920.9577InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.041050.01041InformativeInherited
Biological Process (BP)response to hypoxia1.308e-060.0005833Highly InformativeDirect
Biological Process (BP)myeloid leukocyte activation0.00016615.617e-05Highly InformativeDirect
Biological Process (BP)DNA modification1.195e-128.588e-05Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process1.987e-060.0001285Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00012685.551e-05Highly InformativeDirect
Biological Process (BP)erythrocyte differentiation2.597e-056.916e-05Highly InformativeDirect
Biological Process (BP)establishment of RNA localization2.684e-070.00099Highly InformativeDirect
Biological Process (BP)myeloid cell development1.248e-066.418e-07Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound catabolic process8.974e-072.289e-06Highly InformativeDirect
Biological Process (BP)regulation of gene expression, epigenetic2.304e-090.008291Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.00012710.009959Highly InformativeInherited
Biological Process (BP)phagocytosis0.059950.003459Highly InformativeInherited
Biological Process (BP)T cell differentiation0.00025120.004738Highly InformativeInherited
Biological Process (BP)inorganic anion transport0.019150.1239Highly InformativeInherited
Biological Process (BP)nuclear export1.377e-060.001898Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)cation binding1.783e-060Moderately InformativeDirect
Molecular Function (MF)transition metal ion binding3.536e-120InformativeDirect
Molecular Function (MF)iron ion binding9.447e-150Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 1.231e-05 Least Informative Direct
Biological Process (BP) protein metabolic process 1.053e-10 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0001075 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.004473 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 7.281e-15 Moderately Informative Direct
Biological Process (BP) regulation of biosynthetic process 0.0005773 Moderately Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.000994 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 2.164e-11 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 5.246e-09 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.02565 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.2089 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 0.1715 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.008727 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1188 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.6898 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.1975 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4688 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.283 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.1865 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) muscle system process 0.0009711 Informative Direct
Biological Process (BP) isoprenoid metabolic process 1.558e-11 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cardiovascular system development 0.0006835 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 2.421e-10 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.03548 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.2614 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) tube development 0.1744 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.996 Informative Inherited
Biological Process (BP) blood circulation 0.05688 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.2148 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.01013 Informative Inherited
Biological Process (BP) cell cycle process 1 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.3024 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.009538 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.4158 Informative Inherited
Biological Process (BP) RNA modification 0.01091 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.4059 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.3481 Informative Inherited
Biological Process (BP) central nervous system development 0.899 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.5308 Informative Inherited
Biological Process (BP) actin filament-based process 0.744 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) anion transport 0.988 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) reproductive system development 0.8434 Informative Inherited
Biological Process (BP) response to inorganic substance 0.456 Informative Inherited
Biological Process (BP) RNA processing 0.3647 Informative Inherited
Biological Process (BP) ncRNA metabolic process 0.5458 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.9577 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.01041 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.2872 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) response to hypoxia 0.0005833 Highly Informative Direct
Biological Process (BP) myeloid leukocyte activation 5.617e-05 Highly Informative Direct
Biological Process (BP) DNA modification 8.588e-05 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 1.988e-11 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.0005287 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0001285 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 5.551e-05 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 6.567e-05 Highly Informative Direct
Biological Process (BP) actin filament-based movement 8.249e-05 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 6.916e-05 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.0006494 Highly Informative Direct
Biological Process (BP) establishment of RNA localization 0.00099 Highly Informative Direct
Biological Process (BP) heart contraction 5.613e-06 Highly Informative Direct
Biological Process (BP) myeloid cell development 6.418e-07 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound catabolic process 2.289e-06 Highly Informative Direct
Biological Process (BP) nucleobase-containing compound transport 0.009959 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 1 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.003459 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.004738 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.008291 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 1 Highly Informative Inherited
Biological Process (BP) negative regulation of protein modification process 0.001889 Highly Informative Inherited
Biological Process (BP) inorganic anion transport 0.1239 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.8874 Highly Informative Inherited
Biological Process (BP) nuclear export 0.001898 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.03436 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1282 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.007094 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.2023 Moderately Informative Inherited
Molecular Function (MF) transition metal ion binding 0 Informative Direct
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) DNA binding 0.1194 Informative Inherited
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) transcription regulatory region DNA binding 0.0001059 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0002315 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.004989 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.006354 Informative Inherited
Cellular Component (CC) chromosome 0.1194 Informative Inherited
Cellular Component (CC) chromatin 6.949e-05 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.01633 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase1.846e-11InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.2296Least InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.103Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.2315Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.0249InformativeInherited
Mammalian Phenotype (MP)abnormal myocardium layer morphology0.02288Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05275Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)vascular system0.7641InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2516Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.8007Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.8406Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.9216Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase4.291e-11InformativeDirect
Enzyme Commission (EC)RNA helicase0.0001702InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen0.714InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen3.557e-09Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation2.105e-08Moderately InformativeDirect
Biological processViral RNA replication8.274e-10InformativeDirect
Biological processmRNA splicing0.000563InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainTPR repeat0.0008327Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor1.344e-11Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase3.986e-10Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0008809Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.2214Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis2.21e-13Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism4.447e-08Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.06413Moderately InformativeInherited
UniPathway (UP)energy metabolism0.2884Moderately InformativeInherited
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)plant hormone metabolism0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)carnitine metabolism1.342e-15InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis1.005e-11InformativeDirect
UniPathway (UP)alkaloid metabolism2.058e-07InformativeDirect
UniPathway (UP)pigment biosynthesis0.0008497InformativeDirect
UniPathway (UP)tRNA modification0.009484InformativeInherited
UniPathway (UP)terpene metabolism1InformativeInherited
UniPathway (UP)hydrocarbon biosynthesis0Highly InformativeDirect
UniPathway (UP)plant hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)alkene metabolism0Highly InformativeDirect
UniPathway (UP)organosulfur degradation7.742e-09Highly InformativeDirect
UniPathway (UP)sesquiterpene biosynthesis2.834e-05Highly InformativeDirect
UniPathway (UP)anthocyanin biosynthesis0.0005381Highly InformativeDirect
UniPathway (UP)penicillin biosynthesis0.1541Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


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