SUPERFAMILY 1.75 HMM library and genome assignments server


Clavaminate synthase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double-stranded beta-helix [ 51181] (7)
Superfamily:   Clavaminate synthase-like [ 51197] (13)
Families:   Penicillin synthase-like [ 51198] (4)
  Clavaminate synthase [ 51203]
  Gab protein (hypothetical protein YgaT) [ 63855]
  YhcH-like [ 89413]
  Type II Proline 3-hydroxylase (proline oxidase) [ 63858]
  TauD/TfdA-like [ 75038] (2)
  gamma-Butyrobetaine hydroxylase [ 89416] (2)
  Hypoxia-inducible factor HIF ihhibitor (FIH1) [ 82194]
  PhyH-like [ 141623] (2)
  AlkB-like [ 141628] (2)
  Asparaginyl hydroxylase-like [ 141633]
  YbiU-like [ 141636]
  TehB-like [ 159307] (2)


Superfamily statistics
Genomes (2,063) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 40,810 98,263 31
Proteins 40,338 98,040 31


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism metabolic process3.554e-110Least InformativeDirect
Biological Process (BP)biosynthetic process0.03051Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.78633.446e-05Least InformativeInherited
Biological Process (BP)multicellular organismal process11Least InformativeInherited
Biological Process (BP)developmental process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)localization11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.048451Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.62891Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.86391Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.02971Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process10.0002157Least InformativeInherited
Biological Process (BP)protein metabolic process13.801e-09Least InformativeInherited
Biological Process (BP)response to stimulus0.12041Least InformativeInherited
Biological Process (BP)organic hydroxy compound metabolic process0.00050620.02167Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.044072.496e-11Moderately InformativeInherited
Biological Process (BP)cell differentiation11Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.39441Moderately InformativeInherited
Biological Process (BP)organic substance transport0.80681Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.63361Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.87161Moderately InformativeInherited
Biological Process (BP)organonitrogen compound catabolic process0.56661Moderately InformativeInherited
Biological Process (BP)monocarboxylic acid metabolic process0.036210.008739Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.082751Moderately InformativeInherited
Biological Process (BP)immune system process0.93951Moderately InformativeInherited
Biological Process (BP)homeostatic process0.24331Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.00067880.2379Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.01520.143Moderately InformativeInherited
Biological Process (BP)lipid biosynthetic process0.23160.4767Moderately InformativeInherited
Biological Process (BP)cellular lipid metabolic process2.048e-050.2553Moderately InformativeInherited
Biological Process (BP)cellular localization0.8751Moderately InformativeInherited
Biological Process (BP)cellular response to stress4.922e-050.219Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus1.055e-050.1506Moderately InformativeInherited
Biological Process (BP)isoprenoid metabolic process1.205e-112.148e-11InformativeDirect
Biological Process (BP)organic hydroxy compound biosynthetic process4.836e-083.765e-10InformativeDirect
Biological Process (BP)nitrogen compound transport0.0059730.233InformativeInherited
Biological Process (BP)vesicle-mediated transport11InformativeInherited
Biological Process (BP)pyrimidine-containing compound metabolic process0.010470.01048InformativeInherited
Biological Process (BP)carboxylic acid catabolic process0.2410.4187InformativeInherited
Biological Process (BP)RNA modification1.08e-050.009559InformativeInherited
Biological Process (BP)DNA metabolic process0.0023021InformativeInherited
Biological Process (BP)leukocyte activation0.037410.4356InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.086650.5721InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.45611InformativeInherited
Biological Process (BP)response to inorganic substance0.043610.4886InformativeInherited
Biological Process (BP)cytoplasmic transport0.13590.9721InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.041950.01111InformativeInherited
Biological Process (BP)response to hypoxia2.154e-060.0008565Highly InformativeDirect
Biological Process (BP)myeloid leukocyte activation0.00017876.466e-05Highly InformativeDirect
Biological Process (BP)DNA modification1.252e-126.585e-05Highly InformativeDirect
Biological Process (BP)isoprenoid biosynthetic process1.916e-060.0001421Highly InformativeDirect
Biological Process (BP)antibiotic biosynthetic process0.00019147.977e-05Highly InformativeDirect
Biological Process (BP)erythrocyte differentiation3.46e-059.469e-05Highly InformativeDirect
Biological Process (BP)myeloid cell development1.352e-068.923e-07Highly InformativeDirect
Biological Process (BP)pyrimidine-containing compound catabolic process9.97e-072.554e-06Highly InformativeDirect
Biological Process (BP)regulation of gene expression, epigenetic2.465e-090.009713Highly InformativeInherited
Biological Process (BP)nucleobase-containing compound transport0.00013970.01082Highly InformativeInherited
Biological Process (BP)establishment of RNA localization2.988e-070.001089Highly InformativeInherited
Biological Process (BP)phagocytosis0.066020.004437Highly InformativeInherited
Biological Process (BP)T cell differentiation0.00027040.005899Highly InformativeInherited
Biological Process (BP)nuclear export1.525e-060.002082Highly InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)binding11Least InformativeInherited
Molecular Function (MF)oxidoreductase activity00Moderately InformativeDirect
Molecular Function (MF)cation binding2.642e-060Moderately InformativeDirect
Molecular Function (MF)transition metal ion binding5.524e-120InformativeDirect
Molecular Function (MF)iron ion binding1.508e-140Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge00Highly InformativeDirect
Molecular Function (MF)dioxygenase activity00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 3.446e-05 Least Informative Direct
Biological Process (BP) protein metabolic process 3.801e-09 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0002157 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.02756 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Biological Process (BP) organelle organization 9.054e-13 Moderately Informative Direct
Biological Process (BP) regulation of biosynthetic process 0.0005374 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 2.496e-11 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1.584e-08 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.02167 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.2727 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) single-organism biosynthetic process 0.143 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 1 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.008739 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.001027 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.2379 Moderately Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.4767 Moderately Informative Inherited
Biological Process (BP) RNA metabolic process 1 Moderately Informative Inherited
Biological Process (BP) gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular lipid metabolic process 0.2553 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.219 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1506 Moderately Informative Inherited
Biological Process (BP) isoprenoid metabolic process 2.148e-11 Informative Direct
Biological Process (BP) chromosome organization 0 Informative Direct
Biological Process (BP) cardiovascular system development 0.0008964 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 3.765e-10 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.03941 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.299 Informative Inherited
Biological Process (BP) muscle system process 0.001154 Informative Inherited
Biological Process (BP) cellular component movement 1 Informative Inherited
Biological Process (BP) tube development 0.1917 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1 Informative Inherited
Biological Process (BP) blood circulation 0.06243 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.233 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) monocarboxylic acid biosynthetic process 0.0106 Informative Inherited
Biological Process (BP) cell cycle process 1 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.323 Informative Inherited
Biological Process (BP) vesicle-mediated transport 1 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.01048 Informative Inherited
Biological Process (BP) carboxylic acid catabolic process 0.4187 Informative Inherited
Biological Process (BP) RNA modification 0.009559 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.4356 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 0.3505 Informative Inherited
Biological Process (BP) central nervous system development 0.8365 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 0.5721 Informative Inherited
Biological Process (BP) actin filament-based process 0.7869 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) embryonic morphogenesis 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) reproductive system development 0.8892 Informative Inherited
Biological Process (BP) response to inorganic substance 0.4886 Informative Inherited
Biological Process (BP) RNA processing 0.4059 Informative Inherited
Biological Process (BP) ncRNA metabolic process 0.5905 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.9721 Informative Inherited
Biological Process (BP) response to DNA damage stimulus 0.01111 Informative Inherited
Biological Process (BP) embryo development ending in birth or egg hatching 0.229 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) response to hypoxia 0.0008565 Highly Informative Direct
Biological Process (BP) myeloid leukocyte activation 6.466e-05 Highly Informative Direct
Biological Process (BP) DNA modification 6.585e-05 Highly Informative Direct
Biological Process (BP) amino-acid betaine metabolic process 1.629e-11 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.0005087 Highly Informative Direct
Biological Process (BP) isoprenoid biosynthetic process 0.0001421 Highly Informative Direct
Biological Process (BP) histone modification 0 Highly Informative Direct
Biological Process (BP) antibiotic biosynthetic process 7.977e-05 Highly Informative Direct
Biological Process (BP) peptidyl-lysine modification 8.162e-05 Highly Informative Direct
Biological Process (BP) actin filament-based movement 9.238e-05 Highly Informative Direct
Biological Process (BP) erythrocyte differentiation 9.469e-05 Highly Informative Direct
Biological Process (BP) mitotic cell cycle phase transition 0.0007333 Highly Informative Direct
Biological Process (BP) heart contraction 6.817e-06 Highly Informative Direct
Biological Process (BP) myeloid cell development 8.923e-07 Highly Informative Direct
Biological Process (BP) pyrimidine-containing compound catabolic process 2.554e-06 Highly Informative Direct
Biological Process (BP) nucleobase-containing compound transport 0.01082 Highly Informative Inherited
Biological Process (BP) establishment of RNA localization 0.001089 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 1 Highly Informative Inherited
Biological Process (BP) phagocytosis 0.004437 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.005899 Highly Informative Inherited
Biological Process (BP) regulation of gene expression, epigenetic 0.009713 Highly Informative Inherited
Biological Process (BP) positive regulation of transcription, DNA-dependent 1 Highly Informative Inherited
Biological Process (BP) negative regulation of protein modification process 0.00232 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.9319 Highly Informative Inherited
Biological Process (BP) nuclear export 0.002082 Highly Informative Inherited
Biological Process (BP) angiogenesis 0.03725 Highly Informative Inherited
Biological Process (BP) morphogenesis of embryonic epithelium 0.1357 Highly Informative Inherited
Biological Process (BP) neural tube development 0.03188 Highly Informative Inherited
Biological Process (BP) epithelial tube formation 0.00767 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0 Moderately Informative Direct
Molecular Function (MF) nucleic acid binding 0.259 Moderately Informative Inherited
Molecular Function (MF) transition metal ion binding 0 Informative Direct
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) DNA binding 0.1311 Informative Inherited
Molecular Function (MF) iron ion binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge 0 Highly Informative Direct
Molecular Function (MF) transcription regulatory region DNA binding 0.0002638 Highly Informative Direct
Molecular Function (MF) dioxygenase activity 0 Highly Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.0003653 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.007112 Moderately Informative Inherited
Cellular Component (CC) nucleoplasm part 0.006667 Informative Inherited
Cellular Component (CC) chromosome 0.1441 Informative Inherited
Cellular Component (CC) chromatin 0.0001008 Highly Informative Direct
Cellular Component (CC) nuclear chromosome part 0.01627 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0.8245Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.6674Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.008223Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)RNA-directed RNA polymerase1.846e-11InformativeDirect
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporatio0Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.2286Least InformativeInherited
Mammalian Phenotype (MP)muscle phenotype0.1036Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.2308Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.02482InformativeInherited
Mammalian Phenotype (MP)abnormal cardiac muscle tissue morphology0.05184Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)vascular system0.7641InformativeInherited
Plant ANatomical entity (PAN)plant ovule0.2516Highly InformativeInherited

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferring phosphorous-containing groups1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.8038Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.8395Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.9207Moderately InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen0InformativeDirect
Enzyme Commission (EC)RNA-directed RNA polymerase4.233e-11InformativeDirect
Enzyme Commission (EC)RNA helicase0.00017InformativeDirect
Enzyme Commission (EC)Acting on single donors with incorporation of molecular oxygen0.7123InformativeInherited
Enzyme Commission (EC)With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0Highly InformativeDirect
Enzyme Commission (EC)With incorporation of one atom of oxygen3.54e-09Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processDifferentiation2.067e-08Moderately InformativeDirect
Biological processViral RNA replication8.139e-10InformativeDirect
Biological processmRNA splicing0.0005576InformativeDirect
Biological processAntibiotic biosynthesis0Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainTPR repeat0.0008304Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationRepressor1.369e-11Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase1Moderately InformativeInherited
Post-translational modificationChromatin regulator0InformativeDirect
Post-translational modificationDioxygenase0Highly InformativeDirect
Post-translational modificationRNA-directed RNA polymerase3.914e-10Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0008856Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)aromatic compound metabolism0.2205Least InformativeInherited
UniPathway (UP)biopolymer metabolism1Least InformativeInherited
UniPathway (UP)secondary metabolite metabolism0Moderately InformativeDirect
UniPathway (UP)aromatic compound biosynthesis2.165e-13Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism4.363e-08Moderately InformativeDirect
UniPathway (UP)nitrogen metabolism0.06385Moderately InformativeInherited
UniPathway (UP)energy metabolism0.2885Moderately InformativeInherited
UniPathway (UP)antibiotic biosynthesis0InformativeDirect
UniPathway (UP)plant hormone metabolism0InformativeDirect
UniPathway (UP)flavonoid metabolism0InformativeDirect
UniPathway (UP)phenylpropanoid biosynthesis0InformativeDirect
UniPathway (UP)carnitine metabolism1.341e-15InformativeDirect
UniPathway (UP)amine and polyamine biosynthesis9.841e-12InformativeDirect
UniPathway (UP)alkaloid metabolism2.046e-07InformativeDirect
UniPathway (UP)pigment biosynthesis0.000843InformativeDirect
UniPathway (UP)tRNA modification0.009397InformativeInherited
UniPathway (UP)terpene metabolism1InformativeInherited
UniPathway (UP)hydrocarbon biosynthesis0Highly InformativeDirect
UniPathway (UP)plant hormone biosynthesis0Highly InformativeDirect
UniPathway (UP)tRNA post-transcriptional modification0Highly InformativeDirect
UniPathway (UP)alkene metabolism0Highly InformativeDirect
UniPathway (UP)organosulfur degradation7.704e-09Highly InformativeDirect
UniPathway (UP)sesquiterpene biosynthesis2.425e-05Highly InformativeDirect
UniPathway (UP)anthocyanin biosynthesis0.000538Highly InformativeDirect
UniPathway (UP)penicillin biosynthesis0.1541Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 21 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Clavaminate synthase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 21 hidden Markov models representing the Clavaminate synthase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


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