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Carbonic anhydrase superfamily
SCOP classification
Superfamily statistics
Functional annotation
| General category | Metabolism |
| Detailed category | Other enzymes |
Function annotation of SCOP domain superfamilies
InterPro annotation
| Cross references | IPR001148 SSF51069 Protein matches |
| Abstract | Synonym(s): Carbonic dehydratase, Carbonic anhydrase
Carbonate dehydratase (CA) are zinc metalloenzymes which catalyze the
reversible hydration of carbon dioxide. Eight enzymatic and evolutionary related forms
of carbonic anhydrase are currently known to exist in vertebrates: three cytosolic
isozymes (CA-I, CA-II and CA-III); two membrane-bound forms (CA-IV and CA-VII); a
mitochondrial form (CA-V); a secreted salivary form (CA-VI); and a yet uncharacterised
isozyme. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]
Internal database links
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 10 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a Carbonic anhydrase domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 10 hidden Markov models representing the Carbonic anhydrase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]
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