SUPERFAMILY 1.75 HMM library and genome assignments server


WD40 repeat-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Families:   WD40-repeat [ 50979] (10)
  Cell cycle arrest protein BUB3 [ 110289]


Superfamily statistics
Genomes (1,073) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 104,512 88,796 21
Proteins 95,309 81,017 19


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.00036951.314e-08Least InformativeDirect
Biological Process (BP)single-organism cellular process1.287e-132.131e-06Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis00Least InformativeDirect
Biological Process (BP)regulation of cellular process0.0045570.9389Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.32439.957e-08Least InformativeInherited
Biological Process (BP)localization0.040130.1038Least InformativeInherited
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus0.00014251Least InformativeInherited
Biological Process (BP)multicellular organismal process9.895e-051Least InformativeInherited
Biological Process (BP)developmental process0.00040920.9497Least InformativeInherited
Biological Process (BP)protein metabolic process0.093741Least InformativeInherited
Biological Process (BP)biosynthetic process0.11851Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.40886.512e-07Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process10.1106Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.69390.0002296Least InformativeInherited
Biological Process (BP)organelle organization2.394e-110Moderately InformativeDirect
Biological Process (BP)gene expression1.066e-060Moderately InformativeDirect
Biological Process (BP)RNA metabolic process0.00082940Moderately InformativeDirect
Biological Process (BP)macromolecule localization3.148e-090Moderately InformativeDirect
Biological Process (BP)cellular localization0.00021660Moderately InformativeDirect
Biological Process (BP)regulation of localization11Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)homeostatic process0.85621Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.82420.07283Moderately InformativeInherited
Biological Process (BP)single-organism developmental process11Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.016661Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.13271Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.085551Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.09481Moderately InformativeInherited
Biological Process (BP)signal transduction0.25011Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.26791Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.0020250.0001633Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.78451Moderately InformativeInherited
Biological Process (BP)reproduction0.0090670.09129Moderately InformativeInherited
Biological Process (BP)organ development0.31041Moderately InformativeInherited
Biological Process (BP)cellular protein modification process10.9464Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.76182.78e-14Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.90910.008397Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.45910.2232Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization10.8832Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.64610.01855Moderately InformativeInherited
Biological Process (BP)organic substance transport0.022450.8475Moderately InformativeInherited
Biological Process (BP)microtubule-based process4.983e-060InformativeDirect
Biological Process (BP)cell cycle process1.497e-082.447e-14InformativeDirect
Biological Process (BP)regulation of organelle organization1.144e-052.364e-08InformativeDirect
Biological Process (BP)positive regulation of protein metabolic process0.16840.06645InformativeInherited
Biological Process (BP)positive regulation of cellular component organization0.049530.00677InformativeInherited
Biological Process (BP)regulation of cell cycle0.051361.655e-12InformativeInherited
Biological Process (BP)regulation of ion transport0.40771InformativeInherited
Biological Process (BP)cytoskeleton organization0.68031InformativeInherited
Biological Process (BP)embryonic morphogenesis0.020830.7614InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter2.516e-050.3571InformativeInherited
Biological Process (BP)cell projection organization0.81555.225e-05InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process0.78551InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.2691InformativeInherited
Biological Process (BP)positive regulation of nitrogen compound metabolic process0.033321InformativeInherited
Biological Process (BP)intracellular signal transduction11InformativeInherited
Biological Process (BP)reproductive structure development0.0026910.003043InformativeInherited
Biological Process (BP)membrane organization11InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00036741InformativeInherited
Biological Process (BP)protein transport0.010553.48e-07InformativeInherited
Biological Process (BP)chromosome organization3.581e-060.5335InformativeInherited
Biological Process (BP)response to nutrient levels1.179e-050.02109InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.0018810.3669InformativeInherited
Biological Process (BP)organelle localization0.0082140.185InformativeInherited
Biological Process (BP)nitrogen compound transport0.44911InformativeInherited
Biological Process (BP)cytoplasmic transport0.00040340.07394InformativeInherited
Biological Process (BP)RNA processing0.074530InformativeInherited
Biological Process (BP)autophagy1.756e-077.333e-15Highly InformativeDirect
Biological Process (BP)chromosome segregation1.172e-060.000115Highly InformativeDirect
Biological Process (BP)cellular response to starvation5.834e-056.139e-06Highly InformativeDirect
Biological Process (BP)positive regulation of organelle organization0.00057570.0003767Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.00048342.798e-05Highly InformativeDirect
Biological Process (BP)iron-sulfur cluster assembly02.112e-14Highly InformativeDirect
Biological Process (BP)histone modification04.348e-06Highly InformativeDirect
Biological Process (BP)protein import1.004e-065.251e-08Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification4.624e-080.0008705Highly InformativeDirect
Biological Process (BP)fruiting body development0.00033320.0004639Highly InformativeDirect
Biological Process (BP)establishment of RNA localization2.939e-068.522e-07Highly InformativeDirect
Biological Process (BP)regulation of reproductive process2.626e-062.621e-06Highly InformativeDirect
Biological Process (BP)regulation of transmembrane transport0.40420.8736Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.07150.9688Highly InformativeInherited
Biological Process (BP)microtubule cytoskeleton organization0.0013670.3406Highly InformativeInherited
Biological Process (BP)maintenance of location1.207e-070.1175Highly InformativeInherited
Biological Process (BP)cellular component disassembly0.35370.08115Highly InformativeInherited
Biological Process (BP)nucleus organization1.76e-050.002567Highly InformativeInherited
Biological Process (BP)leukocyte homeostasis0.0044930.06207Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.050810.6558Highly InformativeInherited
Biological Process (BP)regulation of transporter activity0.015330.4444Highly InformativeInherited
Biological Process (BP)protein methylation9.752e-050.001255Highly InformativeInherited
Biological Process (BP)cell cycle checkpoint0.29170.006352Highly InformativeInherited
Biological Process (BP)regulation of mitosis0.0014080.02359Highly InformativeInherited
Biological Process (BP)negative regulation of cell cycle7.133e-050.07953Highly InformativeInherited
Biological Process (BP)negative regulation of mitotic cell cycle phase transition0.077681Highly InformativeInherited
Biological Process (BP)mitosis2.434e-050.00153Highly InformativeInherited
Biological Process (BP)nuclear export0.0025770.05976Highly InformativeInherited
Biological Process (BP)RNA splicing5.941e-051Highly InformativeInherited
Molecular Function (MF)binding0.00067591Least InformativeInherited
Molecular Function (MF)anion binding11Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.0068251Moderately InformativeInherited
Molecular Function (MF)lipid binding0.76060.8525InformativeInherited
Molecular Function (MF)RNA binding0.00047690.3967InformativeInherited
Molecular Function (MF)amide binding0.0013931InformativeInherited
Molecular Function (MF)phosphatidylinositol binding0.0004140.0007272Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding2.801e-070.006149Highly InformativeInherited
Molecular Function (MF)peptide binding0.00022741Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle1.71e-080Least InformativeDirect
Cellular Component (CC)protein complex3.923e-072.853e-11Least InformativeDirect
Cellular Component (CC)intracellular organelle part2.51e-090Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle10.2514Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)membrane0.16151Least InformativeInherited
Cellular Component (CC)cytosol0.00012290.0006188Moderately InformativeDirect
Cellular Component (CC)endomembrane system4.449e-100.0002187Moderately InformativeDirect
Cellular Component (CC)nuclear part00Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.0028251Moderately InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.14070.01976Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.0035761Moderately InformativeInherited
Cellular Component (CC)vesicle11Moderately InformativeInherited
Cellular Component (CC)plasma membrane part0.52351Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.12781.388e-05Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex00InformativeDirect
Cellular Component (CC)nuclear envelope2.922e-130.0004844InformativeDirect
Cellular Component (CC)integral to membrane7.622e-081InformativeInherited
Cellular Component (CC)coated vesicle0.053674.26e-05InformativeInherited
Cellular Component (CC)nucleoplasm part0.37041InformativeInherited
Cellular Component (CC)nuclear DNA-directed RNA polymerase complex0.65161InformativeInherited
Cellular Component (CC)actin cytoskeleton0.09761InformativeInherited
Cellular Component (CC)chromosome3.038e-091InformativeInherited
Cellular Component (CC)kinetochore1.819e-113.94e-07Highly InformativeDirect
Cellular Component (CC)Arp2/3 protein complex9.158e-091.612e-08Highly InformativeDirect
Cellular Component (CC)internal side of plasma membrane09.72e-06Highly InformativeDirect
Cellular Component (CC)extrinsic to plasma membrane1.351e-134.686e-05Highly InformativeDirect
Cellular Component (CC)cullin-RING ubiquitin ligase complex00Highly InformativeDirect
Cellular Component (CC)methylosome2.722e-088.576e-06Highly InformativeDirect
Cellular Component (CC)SMN-Sm protein complex5.901e-063.067e-05Highly InformativeDirect
Cellular Component (CC)pore complex01.421e-12Highly InformativeDirect
Cellular Component (CC)chromatin10.5889Highly InformativeInherited
Cellular Component (CC)transport vesicle0.0031960.001097Highly InformativeInherited
Cellular Component (CC)transcription elongation factor complex6.578e-050.2012Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 6.512e-07 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 1.314e-08 Least Informative Direct
Biological Process (BP) single-organism cellular process 2.131e-06 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 9.957e-08 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0002296 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.9389 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.9497 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 0.1038 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.1106 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) macromolecule catabolic process 1.751e-05 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 2.78e-14 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0001633 Moderately Informative Direct
Biological Process (BP) cellular localization 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.07283 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.466 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.008397 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.2232 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.8169 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.01792 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.6999 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.8832 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.7346 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.9464 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.01855 Moderately Informative Inherited
Biological Process (BP) reproduction 0.09129 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.8475 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.9925 Moderately Informative Inherited
Biological Process (BP) RNA processing 0 Informative Direct
Biological Process (BP) proteolysis 2.758e-05 Informative Direct
Biological Process (BP) microtubule-based process 0 Informative Direct
Biological Process (BP) protein transport 3.48e-07 Informative Direct
Biological Process (BP) vesicle-mediated transport 6.298e-07 Informative Direct
Biological Process (BP) cell cycle process 2.447e-14 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 6.84e-13 Informative Direct
Biological Process (BP) cell projection organization 5.225e-05 Informative Direct
Biological Process (BP) protein catabolic process 4.512e-12 Informative Direct
Biological Process (BP) regulation of organelle organization 2.364e-08 Informative Direct
Biological Process (BP) cellular macromolecular complex assembly 1.202e-05 Informative Direct
Biological Process (BP) ncRNA metabolic process 0.0002957 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 3.282e-07 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 1.216e-08 Informative Direct
Biological Process (BP) regulation of cell cycle 1.655e-12 Informative Direct
Biological Process (BP) organelle assembly 4.953e-13 Informative Direct
Biological Process (BP) positive regulation of protein metabolic process 0.06645 Informative Inherited
Biological Process (BP) regulation of ion transport 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) epithelium development 0.8796 Informative Inherited
Biological Process (BP) response to cytokine stimulus 1 Informative Inherited
Biological Process (BP) protein localization to organelle 0.03047 Informative Inherited
Biological Process (BP) cardiovascular system development 1 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of growth 0.7635 Informative Inherited
Biological Process (BP) sensory organ development 0.2887 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) cytoskeleton organization 1 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.07394 Informative Inherited
Biological Process (BP) positive regulation of transport 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) positive regulation of gene expression 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.00677 Informative Inherited
Biological Process (BP) response to nutrient levels 0.02109 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 0.2782 Informative Inherited
Biological Process (BP) negative regulation of gene expression 0.1041 Informative Inherited
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.1317 Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 1 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.1072 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 0.3843 Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.3571 Informative Inherited
Biological Process (BP) regulation of nucleoside metabolic process 0.4369 Informative Inherited
Biological Process (BP) regulation of nucleotide catabolic process 0.5229 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 1 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 1 Informative Inherited
Biological Process (BP) regulation of purine nucleotide metabolic process 0.7927 Informative Inherited
Biological Process (BP) chromosome organization 0.5335 Informative Inherited
Biological Process (BP) positive regulation of developmental process 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.193 Informative Inherited
Biological Process (BP) membrane organization 1 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 1 Informative Inherited
Biological Process (BP) actin filament-based process 0.04536 Informative Inherited
Biological Process (BP) cellular component movement 0.8331 Informative Inherited
Biological Process (BP) central nervous system development 0.3953 Informative Inherited
Biological Process (BP) locomotion 1 Informative Inherited
Biological Process (BP) localization of cell 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 1 Informative Inherited
Biological Process (BP) protein complex assembly 1 Informative Inherited
Biological Process (BP) cell-cell signaling 1 Informative Inherited
Biological Process (BP) transmission of nerve impulse 1 Informative Inherited
Biological Process (BP) secretion by cell 0.3651 Informative Inherited
Biological Process (BP) reproductive structure development 0.003043 Informative Inherited
Biological Process (BP) single organism reproductive process 0.905 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 1 Informative Inherited
Biological Process (BP) negative regulation of developmental process 1 Informative Inherited
Biological Process (BP) response to light stimulus 0.05944 Informative Inherited
Biological Process (BP) pyrimidine-containing compound metabolic process 0.5265 Informative Inherited
Biological Process (BP) nucleotide biosynthetic process 1 Informative Inherited
Biological Process (BP) ribose phosphate biosynthetic process 0.7199 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.004487 Informative Inherited
Biological Process (BP) generation of neurons 1 Informative