SUPERFAMILY 1.75 HMM library and genome assignments server


WD40 repeat-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Families:   WD40-repeat [ 50979] (10)
  Cell cycle arrest protein BUB3 [ 110289]


Superfamily statistics
Genomes (1,124) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 114,557 128,176 21
Proteins 104,621 117,222 19


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.00027781.63e-08Least InformativeDirect
Biological Process (BP)single-organism cellular process2.751e-141.286e-08Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis00Least InformativeDirect
Biological Process (BP)regulation of cellular process0.0015570.7894Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.4951.627e-06Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process10.1574Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.41292.8e-07Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.7840.0004942Least InformativeInherited
Biological Process (BP)localization0.021620.02146Least InformativeInherited
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)multicellular organismal process1.011e-051Least InformativeInherited
Biological Process (BP)developmental process3.946e-050.4544Least InformativeInherited
Biological Process (BP)protein metabolic process0.066691Least InformativeInherited
Biological Process (BP)biosynthetic process0.1891Least InformativeInherited
Biological Process (BP)response to stimulus0.00015081Least InformativeInherited
Biological Process (BP)organelle organization2.907e-120Moderately InformativeDirect
Biological Process (BP)gene expression4.373e-063.755e-15Moderately InformativeDirect
Biological Process (BP)macromolecule localization7.236e-090Moderately InformativeDirect
Biological Process (BP)cellular localization4.079e-050Moderately InformativeDirect
Biological Process (BP)regulation of protein metabolic process0.82781Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.14781Moderately InformativeInherited
Biological Process (BP)regulation of localization11Moderately InformativeInherited
Biological Process (BP)regulation of biological quality11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.20250.04283Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.85960.01414Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.9741Moderately InformativeInherited
Biological Process (BP)response to organic substance0.12761Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus11Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.026261Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.15461Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.062271Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.10351Moderately InformativeInherited
Biological Process (BP)signal transduction0.1031Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.0013650.0008306Moderately InformativeInherited
Biological Process (BP)reproduction0.0010310.03437Moderately InformativeInherited
Biological Process (BP)organ development0.51441Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.93560.6637Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.80410.0002318Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization10.7636Moderately InformativeInherited
Biological Process (BP)organic substance transport0.021511Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.79343.788e-14Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.61520.0003461Moderately InformativeInherited
Biological Process (BP)microtubule-based process2.687e-060InformativeDirect
Biological Process (BP)regulation of cell cycle process7.921e-050.000522InformativeDirect
Biological Process (BP)cell cycle process1.594e-085.594e-15InformativeDirect
Biological Process (BP)regulation of organelle organization3.955e-061.634e-07InformativeDirect
Biological Process (BP)positive regulation of protein metabolic process0.1810.05267InformativeInherited
Biological Process (BP)positive regulation of cellular component organization0.029730.01344InformativeInherited
Biological Process (BP)regulation of ion transport0.087191InformativeInherited
Biological Process (BP)vesicle-mediated transport0.34241.963e-09InformativeInherited
Biological Process (BP)cytoskeleton organization0.65691InformativeInherited
Biological Process (BP)embryonic morphogenesis0.01640.5902InformativeInherited
Biological Process (BP)cellular component movement0.53670.4762InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.27031InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter1.205e-050.2409InformativeInherited
Biological Process (BP)cell projection organization0.75436.969e-05InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process0.65661InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.20441InformativeInherited
Biological Process (BP)positive regulation of nucleobase-containing compound metabolic process0.024541InformativeInherited
Biological Process (BP)intracellular signal transduction11InformativeInherited
Biological Process (BP)negative regulation of transport0.19580.3595InformativeInherited
Biological Process (BP)regulation of vesicle-mediated transport0.63786.828e-07InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.2082.87e-05InformativeInherited
Biological Process (BP)reproductive system development0.0069550.001221InformativeInherited
Biological Process (BP)cellular membrane organization0.80710.2496InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00066741InformativeInherited
Biological Process (BP)protein transport0.013094.665e-07InformativeInherited
Biological Process (BP)chromosome organization1.266e-060.5701InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.00010580.05202InformativeInherited
Biological Process (BP)regulation of mitotic cell cycle0.0014990.5035InformativeInherited
Biological Process (BP)mitotic cell cycle0.0055380.1192InformativeInherited
Biological Process (BP)organelle localization0.039770.4678InformativeInherited
Biological Process (BP)cytoplasmic transport0.00030360.06131InformativeInherited
Biological Process (BP)nitrogen compound transport0.42361InformativeInherited
Biological Process (BP)response to nutrient levels6.253e-070.01108InformativeInherited
Biological Process (BP)organelle assembly0.98271.547e-12InformativeInherited
Biological Process (BP)protein methylation3.014e-050.0001939Highly InformativeDirect
Biological Process (BP)autophagy1.949e-080Highly InformativeDirect
Biological Process (BP)chromosome segregation2.383e-075.956e-05Highly InformativeDirect
Biological Process (BP)cellular response to starvation1.592e-057.982e-08Highly InformativeDirect
Biological Process (BP)positive regulation of organelle organization0.00015880.0005778Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.00057518.199e-05Highly InformativeDirect
Biological Process (BP)iron-sulfur cluster assembly02.119e-14Highly InformativeDirect
Biological Process (BP)histone modification04.134e-07Highly InformativeDirect
Biological Process (BP)protein import1.083e-061.811e-07Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification9.158e-087.382e-05Highly InformativeDirect
Biological Process (BP)spindle checkpoint1.538e-060.0008224Highly InformativeDirect
Biological Process (BP)establishment of RNA localization3.151e-064.468e-06Highly InformativeDirect
Biological Process (BP)regulation of reproductive process1.052e-062.234e-06Highly InformativeDirect
Biological Process (BP)cellular response to growth factor stimulus0.35851Highly InformativeInherited
Biological Process (BP)regulation of transmembrane transport0.46981Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.0018790.08902Highly InformativeInherited
Biological Process (BP)regulation of transporter activity0.023990.6344Highly InformativeInherited
Biological Process (BP)maintenance of location1.565e-070.1618Highly InformativeInherited
Biological Process (BP)cellular component disassembly0.33870.07603Highly InformativeInherited
Biological Process (BP)nucleus organization2.245e-050.006557Highly InformativeInherited
Biological Process (BP)leukocyte homeostasis0.0039940.06537Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.026110.43Highly InformativeInherited
Biological Process (BP)microtubule-based movement0.65310Highly InformativeInherited
Biological Process (BP)cytoskeleton-dependent intracellular transport0.013290Highly InformativeInherited
Biological Process (BP)cilium organization0.095120Highly InformativeInherited
Biological Process (BP)negative regulation of cell cycle0.00022290.1503Highly InformativeInherited
Biological Process (BP)negative regulation of mitotic cell cycle phase transition0.087421Highly InformativeInherited
Biological Process (BP)regulation of mitosis0.0020540.03993Highly InformativeInherited
Biological Process (BP)mitosis0.00036720.02245Highly InformativeInherited
Biological Process (BP)nuclear export0.021180.2026Highly InformativeInherited
Molecular Function (MF)binding0.00043191Least InformativeInherited
Molecular Function (MF)anion binding11Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.010661Moderately InformativeInherited
Molecular Function (MF)lipid binding0.60080.8225InformativeInherited
Molecular Function (MF)RNA binding0.00042330.5301InformativeInherited
Molecular Function (MF)amide binding0.0015421InformativeInherited
Molecular Function (MF)phosphatidylinositol binding6.086e-050.0005623Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding3.161e-070.009358Highly InformativeInherited
Molecular Function (MF)peptide binding0.00024861Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle1.895e-080Least InformativeDirect
Cellular Component (CC)protein complex2.408e-075.196e-12Least InformativeDirect
Cellular Component (CC)intracellular organelle part2.966e-080Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.65410.02348Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)membrane0.30481Least InformativeInherited
Cellular Component (CC)cytosol0.00012840.0001333Moderately InformativeDirect
Cellular Component (CC)endomembrane system4.072e-090.0005254Moderately InformativeDirect
Cellular Component (CC)nuclear part00Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.0030871Moderately InformativeInherited
Cellular Component (CC)cell projection0.094734.119e-07Moderately InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.085070.04524Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.0038711Moderately InformativeInherited
Cellular Component (CC)vesicle11Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.18413.345e-06Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex00InformativeDirect
Cellular Component (CC)nuclear envelope8.745e-130.0007768InformativeDirect
Cellular Component (CC)integral to membrane1.391e-071InformativeInherited
Cellular Component (CC)coated vesicle0.064991.119e-05InformativeInherited
Cellular Component (CC)nucleoplasm part0.099810.3921InformativeInherited
Cellular Component (CC)nuclear DNA-directed RNA polymerase complex0.44940.9428InformativeInherited
Cellular Component (CC)actin cytoskeleton0.064351InformativeInherited
Cellular Component (CC)chromosome4.445e-100.9677InformativeInherited
Cellular Component (CC)kinetochore1.267e-121.429e-07Highly InformativeDirect
Cellular Component (CC)Arp2/3 protein complex7.016e-091.679e-08Highly InformativeDirect
Cellular Component (CC)extrinsic to plasma membrane1.182e-136.173e-05Highly InformativeDirect
Cellular Component (CC)cullin-RING ubiquitin ligase complex00Highly InformativeDirect
Cellular Component (CC)pore complex09.064e-13Highly InformativeDirect
Cellular Component (CC)chromatin10.9845Highly InformativeInherited
Cellular Component (CC)intraflagellar transport particle0.02193.15e-10Highly InformativeInherited
Cellular Component (CC)transport vesicle0.0037510.0002767Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 1.627e-06 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 1.63e-08 Least Informative Direct
Biological Process (BP) single-organism cellular process 1.286e-08 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 2.8e-07 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0004942 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.7894 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.4544 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 0.02146 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.1574 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) gene expression 3.755e-15 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0002318 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 3.788e-14 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.0003461 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0008306 Moderately Informative Direct
Biological Process (BP) cellular localization 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.01414 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.4164 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.04283 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.9805 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.01094 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.7636 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.7438 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.5091 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.6637 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.03437 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) developmental process involved in reproduction 2.87e-05 Informative Direct
Biological Process (BP) RNA processing 0 Informative Direct
Biological Process (BP) proteolysis 2.189e-05 Informative Direct
Biological Process (BP) microtubule-based process 0 Informative Direct
Biological Process (BP) regulation of cell cycle process 0.000522 Informative Direct
Biological Process (BP) protein transport 4.665e-07 Informative Direct
Biological Process (BP) vesicle-mediated transport 1.963e-09 Informative Direct
Biological Process (BP) cell cycle process 5.594e-15 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 2.746e-12 Informative Direct
Biological Process (BP) cell projection organization 6.969e-05 Informative Direct
Biological Process (BP) protein catabolic process 1.4e-12 Informative Direct
Biological Process (BP) regulation of organelle organization 1.634e-07 Informative Direct
Biological Process (BP) cellular macromolecular complex assembly 3.873e-06 Informative Direct
Biological Process (BP) ncRNA metabolic process 0.0003351 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 2.656e-07 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 6.664e-09 Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 6.828e-07 Informative Direct
Biological Process (BP) protein modification by small protein conjugation or removal 2.419e-12 Informative Direct
Biological Process (BP) organelle assembly 1.547e-12 Informative Direct
Biological Process (BP) positive regulation of protein metabolic process 0.05267 Informative Inherited
Biological Process (BP) regulation of ion transport 1 Informative Inherited
Biological Process (BP) tissue morphogenesis 1 Informative Inherited
Biological Process (BP) epithelium development 0.7303 Informative Inherited
Biological Process (BP) protein localization to organelle 0.0305 Informative Inherited
Biological Process (BP) response to cytokine stimulus 1 Informative Inherited
Biological Process (BP) cardiovascular system development 1 Informative Inherited
Biological Process (BP) organ morphogenesis 1 Informative Inherited
Biological Process (BP) regulation of growth 0.7533 Informative Inherited
Biological Process (BP) sensory organ development 0.2748 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative