SUPERFAMILY 1.75 HMM library and genome assignments server


WD40 repeat-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Families:   WD40-repeat [ 50979] (10)
  Cell cycle arrest protein BUB3 [ 110289]


Superfamily statistics
Genomes (1,123) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 114,549 128,176 21
Proteins 104,616 117,222 19


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular macromolecule metabolic process0.0002961.317e-08Least InformativeDirect
Biological Process (BP)single-organism cellular process2.888e-141.077e-07Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis00Least InformativeDirect
Biological Process (BP)regulation of cellular process0.001460.8176Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.48981.251e-06Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process10.1408Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.40662.045e-07Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.77960.0004031Least InformativeInherited
Biological Process (BP)localization0.020310.03879Least InformativeInherited
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)multicellular organismal process1.011e-051Least InformativeInherited
Biological Process (BP)developmental process3.805e-050.508Least InformativeInherited
Biological Process (BP)protein metabolic process0.067851Least InformativeInherited
Biological Process (BP)biosynthetic process0.19081Least InformativeInherited
Biological Process (BP)response to stimulus0.00012641Least InformativeInherited
Biological Process (BP)organelle organization2.929e-120Moderately InformativeDirect
Biological Process (BP)gene expression4.435e-065.59e-15Moderately InformativeDirect
Biological Process (BP)macromolecule localization7.29e-091.936e-15Moderately InformativeDirect
Biological Process (BP)cellular localization3.792e-050Moderately InformativeDirect
Biological Process (BP)regulation of protein metabolic process0.80351Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process0.12971Moderately InformativeInherited
Biological Process (BP)regulation of localization11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.18080.04937Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)homeostatic process0.91891Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.85160.01801Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.93411Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus0.97161Moderately InformativeInherited
Biological Process (BP)response to organic substance0.12241Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus11Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.026381Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.15531Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.068341Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.11371Moderately InformativeInherited
Biological Process (BP)signal transduction0.11821Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.0012050.0004233Moderately InformativeInherited
Biological Process (BP)reproduction0.0019330.0416Moderately InformativeInherited
Biological Process (BP)organ development0.5051Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.93640.682Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.80830.0006597Moderately InformativeInherited
Biological Process (BP)macromolecular complex subunit organization10.8833Moderately InformativeInherited
Biological Process (BP)organic substance transport0.022141Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.78419.888e-14Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.60380.001353Moderately InformativeInherited
Biological Process (BP)microtubule-based process2.945e-060InformativeDirect
Biological Process (BP)cell cycle process1.692e-084.447e-14InformativeDirect
Biological Process (BP)regulation of organelle organization5.394e-061.259e-07InformativeDirect
Biological Process (BP)positive regulation of protein modification process0.088140.005006InformativeInherited
Biological Process (BP)positive regulation of cellular component organization0.02840.01097InformativeInherited
Biological Process (BP)regulation of cell cycle process8.355e-050.001139InformativeInherited
Biological Process (BP)regulation of ion transport0.087351InformativeInherited
Biological Process (BP)vesicle-mediated transport0.354.49e-09InformativeInherited
Biological Process (BP)cytoskeleton organization0.67421InformativeInherited
Biological Process (BP)embryonic morphogenesis0.016860.6037InformativeInherited
Biological Process (BP)cellular component movement0.54670.4298InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.26821InformativeInherited
Biological Process (BP)regulation of transcription from RNA polymerase II promoter9.311e-060.2886InformativeInherited
Biological Process (BP)cell projection organization0.74414.602e-05InformativeInherited
Biological Process (BP)positive regulation of macromolecule biosynthetic process0.65411InformativeInherited
Biological Process (BP)positive regulation of cellular biosynthetic process0.19871InformativeInherited
Biological Process (BP)positive regulation of nitrogen compound metabolic process0.020091InformativeInherited
Biological Process (BP)intracellular signal transduction11InformativeInherited
Biological Process (BP)negative regulation of transport0.20250.314InformativeInherited
Biological Process (BP)regulation of vesicle-mediated transport0.62213.743e-07InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.29414.893e-05InformativeInherited
Biological Process (BP)reproductive system development0.0070810.001124InformativeInherited
Biological Process (BP)cellular membrane organization0.8090.2151InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00064070.9669InformativeInherited
Biological Process (BP)protein transport0.012383.982e-07InformativeInherited
Biological Process (BP)chromosome organization1.235e-060.575InformativeInherited
Biological Process (BP)negative regulation of cellular component organization9.366e-050.0407InformativeInherited
Biological Process (BP)regulation of mitotic cell cycle0.0015850.3603InformativeInherited
Biological Process (BP)mitotic cell cycle0.0053620.06789InformativeInherited
Biological Process (BP)organelle localization0.038340.3879InformativeInherited
Biological Process (BP)cytoplasmic transport0.00035070.03276InformativeInherited
Biological Process (BP)nitrogen compound transport0.43051InformativeInherited
Biological Process (BP)response to nutrient levels4.675e-070.01068InformativeInherited
Biological Process (BP)organelle assembly0.97181.416e-12InformativeInherited
Biological Process (BP)protein methylation2.772e-050.0001703Highly InformativeDirect
Biological Process (BP)autophagy2.267e-080Highly InformativeDirect
Biological Process (BP)chromosome segregation2.445e-079.823e-05Highly InformativeDirect
Biological Process (BP)cellular response to starvation1.419e-051.082e-07Highly InformativeDirect
Biological Process (BP)positive regulation of organelle organization0.00019160.0005238Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.00059128.129e-05Highly InformativeDirect
Biological Process (BP)iron-sulfur cluster assembly02.116e-14Highly InformativeDirect
Biological Process (BP)histone modification03.667e-07Highly InformativeDirect
Biological Process (BP)protein import1.123e-061.209e-07Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification9.903e-087.12e-05Highly InformativeDirect
Biological Process (BP)spindle checkpoint1.682e-060.0003277Highly InformativeDirect
Biological Process (BP)establishment of RNA localization3.298e-063.639e-06Highly InformativeDirect
Biological Process (BP)regulation of reproductive process1.165e-061.953e-06Highly InformativeDirect
Biological Process (BP)cellular response to growth factor stimulus0.36141Highly InformativeInherited
Biological Process (BP)regulation of transmembrane transport0.46980.994Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.0014670.08043Highly InformativeInherited
Biological Process (BP)regulation of transporter activity0.024190.6353Highly InformativeInherited
Biological Process (BP)maintenance of location1.681e-070.152Highly InformativeInherited
Biological Process (BP)cellular component disassembly0.34070.1073Highly InformativeInherited
Biological Process (BP)nucleus organization2.298e-050.006734Highly InformativeInherited
Biological Process (BP)leukocyte homeostasis0.004040.06511Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.026020.429Highly InformativeInherited
Biological Process (BP)microtubule-based movement0.64950Highly InformativeInherited
Biological Process (BP)cilium organization0.081460Highly InformativeInherited
Biological Process (BP)negative regulation of cell cycle0.00027460.1378Highly InformativeInherited
Biological Process (BP)negative regulation of mitotic cell cycle phase transition0.085771Highly InformativeInherited
Biological Process (BP)regulation of mitosis0.0020780.02354Highly InformativeInherited
Biological Process (BP)mitosis0.00036680.01513Highly InformativeInherited
Biological Process (BP)nuclear export0.021590.2102Highly InformativeInherited
Molecular Function (MF)binding0.00039971Least InformativeInherited
Molecular Function (MF)anion binding11Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.010481Moderately InformativeInherited
Molecular Function (MF)lipid binding0.60750.8026InformativeInherited
Molecular Function (MF)RNA binding0.00039270.53InformativeInherited
Molecular Function (MF)amide binding0.0015961InformativeInherited
Molecular Function (MF)phosphatidylinositol binding6.243e-050.0004025Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding3.595e-070.009306Highly InformativeInherited
Molecular Function (MF)peptide binding0.00025511Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle7.309e-090Least InformativeDirect
Cellular Component (CC)protein complex2.229e-071.21e-11Least InformativeDirect
Cellular Component (CC)intracellular organelle part1.158e-080Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.62370.0264Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)membrane0.28591Least InformativeInherited
Cellular Component (CC)cytosol0.00012060.0005215Moderately InformativeDirect
Cellular Component (CC)endomembrane system1.094e-090.0001272Moderately InformativeDirect
Cellular Component (CC)nuclear part00Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.0032981Moderately InformativeInherited
Cellular Component (CC)cell projection0.18042.341e-07Moderately InformativeInherited
Cellular Component (CC)intracellular organelle lumen0.059820.05986Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.0043941Moderately InformativeInherited
Cellular Component (CC)vesicle11Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cytoskeleton0.24021.436e-06Moderately InformativeInherited
Cellular Component (CC)ubiquitin ligase complex00InformativeDirect
Cellular Component (CC)nuclear envelope2.071e-120.0008088InformativeDirect
Cellular Component (CC)integral to membrane1.37e-071InformativeInherited
Cellular Component (CC)coated vesicle0.060667.948e-06InformativeInherited
Cellular Component (CC)nucleoplasm part0.10890.3905InformativeInherited
Cellular Component (CC)nuclear DNA-directed RNA polymerase complex0.47320.9244InformativeInherited
Cellular Component (CC)actin cytoskeleton0.06281InformativeInherited
Cellular Component (CC)chromosome8.739e-101InformativeInherited
Cellular Component (CC)kinetochore1.566e-121.198e-07Highly InformativeDirect
Cellular Component (CC)Arp2/3 protein complex7.302e-091.489e-08Highly InformativeDirect
Cellular Component (CC)extrinsic to plasma membrane1.284e-136.139e-05Highly InformativeDirect
Cellular Component (CC)cullin-RING ubiquitin ligase complex00Highly InformativeDirect
Cellular Component (CC)pore complex07.24e-13Highly InformativeDirect
Cellular Component (CC)chromatin10.6815Highly InformativeInherited
Cellular Component (CC)intraflagellar transport particle0.022152.617e-10Highly InformativeInherited
Cellular Component (CC)transport vesicle0.0037890.0002904Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 1.251e-06 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 1.317e-08 Least Informative Direct
Biological Process (BP) single-organism cellular process 1.077e-07 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 2.045e-07 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0004031 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.8176 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.508 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 0.03879 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.1408 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) gene expression 5.59e-15 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0 Moderately Informative Direct
Biological Process (BP) macromolecule localization 1.936e-15 Moderately Informative Direct
Biological Process (BP) cellular response to stress 0.0006597 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 9.888e-14 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.0004233 Moderately Informative Direct
Biological Process (BP) cellular localization 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.01801 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.5305 Moderately Informative Inherited
Biological Process (BP) signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.04937 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.01404 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) immune system process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) tissue development 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.8833 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.7911 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.5883 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.682 Moderately Informative Inherited
Biological Process (BP) system process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.001353 Moderately Informative Inherited
Biological Process (BP) reproduction 0.0416 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) developmental process involved in reproduction 4.893e-05 Informative Direct
Biological Process (BP) RNA processing 0 Informative Direct
Biological Process (BP) proteolysis 5.682e-05 Informative Direct
Biological Process (BP) microtubule-based process 0 Informative Direct
Biological Process (BP) protein transport 3.982e-07 Informative Direct
Biological Process (BP) vesicle-mediated transport 4.49e-09 Informative Direct
Biological Process (BP) cell cycle process 4.447e-14 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 4.525e-12 Informative Direct
Biological Process (BP) cell projection organization 4.602e-05 Informative Direct
Biological Process (BP) protein catabolic process 1.083e-11 Informative Direct
Biological Process (BP) regulation of organelle organization 1.259e-07 Informative Direct
Biological Process (BP) cellular macromolecular complex assembly 6.208e-06 Informative Direct
Biological Process (BP) ncRNA metabolic process 0.0003561 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 1.011e-06 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 2.134e-08 Informative Direct
Biological Proce