SUPERFAMILY 1.75 HMM library and genome assignments server

Herpes virus serine proteinase, assemblin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Herpes virus serine proteinase, assemblin [ 50788]
Superfamily:   Herpes virus serine proteinase, assemblin [ 50789]
Families:   Herpes virus serine proteinase, assemblin [ 50790] (5)


Superfamily statistics
Genomes (162) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 180 1,517 17
Proteins 180 1,517 17


Functional annotation
General category Processes_IC
Detailed category Proteases

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processVirus exit from host cell0Highly InformativeDirect
Cellular componentHost nucleus0InformativeDirect
Cellular componentHost cytoplasm0InformativeDirect
Coding sequence diversityAlternative promoter usage0Moderately InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationProtease0Moderately InformativeDirect
Post-translational modificationSerine protease0.000000000000744InformativeDirect
Post-translational modificationPhosphoprotein0.00000005381Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001847 SSF50789 Protein matches
Abstract

This group of serine peptidases belong to MEROPS peptidase family S21 (assemblin family, clan 21).

A number of viral proteases have been discovered and their sequence similarity is very low. Studies with protease inhibitors suggest that the Herpesviridae protease is a serine protease belonging to either the trypsin-like or subtilisin-like families; it is not inhibited by inhibitors of Cys, Asp or metallo proteases.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Herpes virus serine proteinase, assemblin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Herpes virus serine proteinase, assemblin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]