SUPERFAMILY 1.75 HMM library and genome assignments server


Barwin-like endoglucanases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Double psi beta-barrel [ 50684] (2)
Superfamily:   Barwin-like endoglucanases [ 50685] (4)
Families:   Eng V-like [ 50686] (2)
  Pollen allergen PHL P 1 N-terminal domain [ 82135]
  Barwin [ 50689]
  MLTA-like [ 159195]


Superfamily statistics
Genomes (1,971) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 9,934 24,695 16
Proteins 9,820 24,629 16


Functional annotation
General category Metabolism
Detailed category Polysaccharide metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) developmental process 0.5214 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.9465 Least Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.00161 Moderately Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 1.245e-05 Informative Direct
Cellular Component (CC) external encapsulating structure 1.197e-08 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl1.286e-12Moderately InformativeDirect
Enzyme Commission (EC)Cellulase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)root system0.3397Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.6642Least InformativeInherited
Plant ANatomical entity (PAN)root tip0.0001506InformativeDirect
Plant ANatomical entity (PAN)lateral root2.294e-06Highly InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.0005816Least InformativeDirect
Enzyme Commission (EC)Lyases0.004204Least InformativeInherited
Enzyme Commission (EC)Glycosylases1.643e-11Moderately InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0.0001996Moderately InformativeDirect
Enzyme Commission (EC)Cellulase0Highly InformativeDirect
Enzyme Commission (EC)Acting on polysaccharides3.402e-11Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0.01018Moderately InformativeInherited
Biological processCell wall biogenesis/degradation0InformativeDirect
Biological processPlant defense5.24e-09InformativeDirect
Biological processPolysaccharide degradation2.268e-07InformativeDirect
Biological processCellulose degradation4.073e-11Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentCell wall0Highly InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionChitin-binding7.129e-10Highly InformativeDirect
Post-translational modificationDisulfide bond1.217e-10Least InformativeDirect
Post-translational modificationGlycoprotein1.826e-06Least InformativeDirect
Post-translational modificationPalmitate5.261e-12Moderately InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR009009 SSF50685 Protein matches
Abstract

Beta barrels are commonly observed in protein structures. They are classified in terms of two integral parameters: the number of strands in the sheet, n, and the shear number, S, a measure of the stagger of the strands in the beta-sheet. These two parameters have been shown to determine the major geometrical features of beta-barrels. Six-stranded beta-barrels with a pseudo-twofold axis are found in several proteins. One involving parallel strands forming two psi structures is known as the double-psi barrel. The first psi structure consists of the loop connecting strands beta1 and beta2 (a 'psi loop') and the strand beta5, whereas the second psi structure consists of the loop connecting strands beta4 and beta5 and the strand beta2. All the psi structures in double-psi barrels have a unique handedness, in that beta1 (beta4), beta2 (beta5) and the loop following beta5 (beta2) form a right-handed helix. The unique handedness may be related to the fact that the twisting angle between the parallel pair of strands is always larger than that between the antiparallel pair [PubMed10368289].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Barwin-like endoglucanases domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 8 hidden Markov models representing the Barwin-like endoglucanases superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]