SUPERFAMILY 1.75 HMM library and genome assignments server


Concanavalin A-like lectins/glucanases superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Concanavalin A-like lectins/glucanases [ 49898]
Superfamily:   Concanavalin A-like lectins/glucanases [ 49899] (25)
Families:   Legume lectins [ 49900] (4)
  Lectin leg-like [ 74904] (3)
  Glycosyl hydrolases family 16 [ 49925] (5)
  Galectin (animal S-lectin) [ 49932] (8)
  Laminin G-like module [ 49944] (6)
  Thrombospondin C-terminal domain [ 101643]
  Pentraxin (pentaxin) [ 49951] (2)
  Calnexin/calreticulin [ 69236]
  vp4 sialic acid binding domain [ 74907]
  Hypothetical protein YesU [ 101646]
  Alginate lyase [ 101649] (3)
  Clostridium neurotoxins, the second last domain [ 49956] (2)
  Exotoxin A, N-terminal domain [ 49962]
  Vibrio cholerae sialidase, N-terminal and insertion domains [ 49965]
  Leech intramolecular trans-sialidase, N-terminal domain [ 49968]
  Trypanosoma sialidase, C-terminal domain [ 82038]
  Glycosyl hydrolase family 7 catalytic core [ 49971]
  Glycosyl hydrolases family 32 C-terminal domain [ 101652] (2)
  Xylanase/endoglucanase 11/12 [ 49978] (2)
  Peptidase A4 [ 101656] (2)
  Alpha-L-arabinofuranosidase B, N-terminal domain [ 110143]
  SPRY domain [ 141154] (5)
  Beta-D-xylosidase C-terminal domain-like [ 141161]
  SO2946-like [ 141167]
  MAM domain [ 141170]


Superfamily statistics
Genomes (1,724) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 54,529 76,776 236
Proteins 42,823 65,227 228


Functional annotation
General category Metabolism
Detailed category Secondary metabolism

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis2.63e-090Least InformativeDirect
Biological Process (BP)single-organism cellular process0.00023570Least InformativeDirect
Biological Process (BP)developmental process0.0002870Least InformativeDirect
Biological Process (BP)localization13.384e-10Least InformativeInherited
Biological Process (BP)regulation of cellular process0.97670.577Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.0021890.8163Least InformativeInherited
Biological Process (BP)multicellular organismal process0.0092740Least InformativeInherited
Biological Process (BP)carbohydrate metabolic process6.065e-131.628e-06Moderately InformativeDirect
Biological Process (BP)cell differentiation0.00011480Moderately InformativeDirect
Biological Process (BP)cellular localization0.56260.0002394Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.81760.2429Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.057981.81e-05Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.013634.488e-08Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.11593.538e-12Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.26979.15e-07Moderately InformativeInherited
Biological Process (BP)tissue development0.051750.1061Moderately InformativeInherited
Biological Process (BP)organ development0.47030.5127Moderately InformativeInherited
Biological Process (BP)system process0.73066.535e-06Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.0087841Moderately InformativeInherited
Biological Process (BP)nervous system development0.85331.098e-06Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis11Moderately InformativeInherited
Biological Process (BP)polysaccharide metabolic process01.147e-10InformativeDirect
Biological Process (BP)carbohydrate catabolic process2.573e-107.734e-06InformativeDirect
Biological Process (BP)biological adhesion0.00019030InformativeDirect
Biological Process (BP)cellular membrane organization0.47472.612e-05InformativeInherited
Biological Process (BP)regulation of nervous system development0.00028240.00245InformativeInherited
Biological Process (BP)regulation of cellular component biogenesis0.01564.871e-09InformativeInherited
Biological Process (BP)synaptic transmission0.022542.318e-07InformativeInherited
Biological Process (BP)regulation of cell development0.120.002674InformativeInherited
Biological Process (BP)muscle tissue development0.0020310.01653InformativeInherited
Biological Process (BP)muscle structure development0.0013660.009903InformativeInherited
Biological Process (BP)cellular carbohydrate metabolic process2.006e-050.03006InformativeInherited
Biological Process (BP)cell wall macromolecule metabolic process01.739e-12Highly InformativeDirect
Biological Process (BP)polysaccharide catabolic process5.593e-125.835e-11Highly InformativeDirect
Biological Process (BP)extracellular matrix organization3.709e-060Highly InformativeDirect
Biological Process (BP)muscle fiber development3.541e-050.0004469Highly InformativeDirect
Biological Process (BP)protein localization to membrane0.0001150Highly InformativeDirect
Biological Process (BP)muscle organ development0.00022461.999e-06Highly InformativeDirect
Biological Process (BP)plasma membrane organization0.00055510Highly InformativeDirect
Biological Process (BP)cellular glucan metabolic process0.011430.2444Highly InformativeInherited
Molecular Function (MF)hydrolase activity0.0063750.9843Least InformativeInherited
Molecular Function (MF)binding0.29949.12e-06Least InformativeInherited
Molecular Function (MF)transferase activity0.57091Least InformativeInherited
Molecular Function (MF)hydrolase activity, acting on glycosyl bonds00InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups1.037e-060.007407InformativeInherited
Molecular Function (MF)channel regulator activity0.00038076.021e-15Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring hexosyl groups2.36e-080.02379Highly InformativeInherited
Cellular Component (CC)extracellular region1.72e-080Moderately InformativeDirect
Cellular Component (CC)extracellular matrix1.336e-130InformativeDirect
Cellular Component (CC)extracellular matrix part1.211e-080Highly InformativeDirect
Cellular Component (CC)proteinaceous extracellular matrix2.386e-070Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) localization 3.384e-10 Least Informative Direct
Biological Process (BP) response to stimulus 0.0004319 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.577 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.8163 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.3894 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1.628e-06 Moderately Informative Direct
Biological Process (BP) cell differentiation 0 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 4.488e-08 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1.81e-05 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 3.538e-12 Moderately Informative Direct
Biological Process (BP) single-organism developmental process 9.15e-07 Moderately Informative Direct
Biological Process (BP) immune system process 1.131e-10 Moderately Informative Direct
Biological Process (BP) cellular localization 0.0002394 Moderately Informative Direct
Biological Process (BP) system process 6.535e-06 Moderately Informative Direct
Biological Process (BP) nervous system development 1.098e-06 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 5.704e-05 Moderately Informative Direct
Biological Process (BP) regulation of localization 1.015e-06 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0.2429 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.2009 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.8786 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.001019 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.1328 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.13 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.07928 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.001321 Moderately Informative Inherited
Biological Process (BP) tissue development 0.1061 Moderately Informative Inherited
Biological Process (BP) organ development 0.5127 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.003623 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.004036 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) polysaccharide metabolic process 1.147e-10 Informative Direct
Biological Process (BP) carbohydrate catabolic process 7.734e-06 Informative Direct
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) secretion 1.544e-08 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 4.871e-09 Informative Direct
Biological Process (BP) synaptic transmission 2.318e-07 Informative Direct
Biological Process (BP) regulation of growth 0.0003895 Informative Direct
Biological Process (BP) localization of cell 1.711e-13 Informative Direct
Biological Process (BP) immune response 5.749e-05 Informative Direct
Biological Process (BP) defense response 4.874e-05 Informative Direct
Biological Process (BP) generation of neurons 4.087e-06 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) cellular membrane organization 2.612e-05 Informative Direct
Biological Process (BP) cellular component movement 3.127e-08 Informative Direct
Biological Process (BP) cell projection organization 0 Informative Direct
Biological Process (BP) negative regulation of developmental process 2.076e-15 Informative Direct
Biological Process (BP) response to external stimulus 7.663e-14 Informative Direct
Biological Process (BP) positive regulation of immune system process 6.676e-12 Informative Direct
Biological Process (BP) cellular component morphogenesis 2.731e-11 Informative Direct
Biological Process (BP) organ morphogenesis 7.157e-06 Informative Direct
Biological Process (BP) positive regulation of signal transduction 9.043e-06 Informative Direct
Biological Process (BP) regulation of immune response 9.684e-06 Informative Direct
Biological Process (BP) regulation of locomotion 1.291e-05 Informative Direct
Biological Process (BP) protein modification by small protein conjugation or removal 2.346e-05 Informative Direct
Biological Process (BP) regulation of cellular component movement 4.404e-05 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 7.089e-05 Informative Direct
Biological Process (BP) regulation of intracellular protein kinase cascade 9.724e-05 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.000302 Informative Direct
Biological Process (BP) regulation of intracellular transport 0.000323 Informative Direct
Biological Process (BP) positive regulation of multicellular organismal process 0.0009123 Informative Direct
Biological Process (BP) regulation of system process 0.08098 Informative Inherited
Biological Process (BP) negative regulation of cell death 1 Informative Inherited
Biological Process (BP) protein transport 0.2893 Informative Inherited
Biological Process (BP) response to organic nitrogen 0.2602 Informative Inherited
Biological Process (BP) cellular response to nitrogen compound 0.12 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.5839 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.05621 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.218 Informative Inherited
Biological Process (BP) metal ion transport 0.1991 Informative Inherited
Biological Process (BP) transmembrane transport 1 Informative Inherited
Biological Process (BP) protein oligomerization 0.002226 Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 0.3508 Informative Inherited
Biological Process (BP) gland development 0.5814 Informative Inherited
Biological Process (BP) growth 0.1183 Informative Inherited
Biological Process (BP) tube development 0.8808 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.08052 Informative Inherited
Biological Process (BP) metal ion homeostasis 0.01135 Informative Inherited
Biological Process (BP) sensory organ development 0.0195 Informative Inherited
Biological Process (BP) regulation of hydrolase activity 0.2076 Informative Inherited
Biological Process (BP) regulation of ion transport 0.1376 Informative Inherited
Biological Process (BP) chromosome organization 1 Informative Inherited
Biological Process (BP) regulation of secretion 0.1424 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.00245 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 0.5986 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.882 Informative Inherited
Biological Process (BP) muscle structure development 0.009903 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 0.7365 Informative Inherited
Biological Process (BP) positive regulation of transport 0.4792 Informative Inherited
Biological Process (BP) pigment metabolic process 0.2348 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.006733 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.6075 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.7394 Informative Inherited
Biological Process (BP) positive regulation of developmental process 0.2095 Informative Inherited
Biological Process (BP) regulation of cell development 0.002674 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) negative regulation of molecular function 0.903 Informative Inherited
Biological Process (BP) apoptotic process 0.4929 Informative Inherited
Biological Process (BP) response to other organism 0.008792 Informative Inherited
Biological Process (BP) response to cytokine stimulus 0.3456 Informative Inherited
Biological Process (BP) regulation of apoptotic process 1 Informative Inherited
Biological Process (BP) regulation of protein localization 0.1148 Informative Inherited
Biological Process (BP) regulation of cytokine production 0.04798 Informative Inherited
Biological Process (BP) DNA metabolic process 1 Informative Inherited
Biological Process (BP) regulation of kinase activity 0.3267 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 1 Informative Inherited
Biological Process (BP) positive regulation of phosphorus metabolic process 0.1985 Informative Inherited
Biological Process (BP) positive regulation of protein metabolic process 0.6647 Informative Inherited
Biological Process (BP) response to inorganic substance 1 Informative Inherited
Biological Process (BP) regulation of response to stress 0.009746 Informative Inherited
Biological Process (BP) embryonic organ development 1 Informative Inherited
Biological Process (BP) central nervous system development 1 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 1 Informative Inherited
Biological Process (BP) multi-organism reproductive process 0.2004 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.6123 Informative Inherited
Biological Process (BP) protein phosphorylation 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) cellular cation homeostasis 0.7046 Informative Inherited
Biological Process (BP) cytoplasmic transport 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.6756 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.03195 Informative Inherited
Biological Process (BP) dephosphorylation 0.002004 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 0.03006 Informative Inherited
Biological Process (BP) muscle tissue development 0.01653 Informative Inherited
Biological Process (BP) cardiovascular system development 0.008844 Informative Inherited
Biological Process (BP) blood circulation 0.9898 Informative Inherited
Biological Process (BP) hematopoietic or lymphoid organ development 1 Informative Inherited
Biological Process (BP) cell activation 1 Informative Inherited
Biological Process (BP) immune effector process 1 Informative Inherited
Biological Process (BP) regulation of body fluid levels 0.5571 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 0.1019 Informative Inherited
Biological Process (BP) anatomical structure homeostasis 0.00151 Informative Inherited
Biological Process (BP) multicellular organismal homeostasis 0.00351 Informative Inherited
Biological Process (BP) response to wounding 0.02832 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) cell wall macromolecule metabolic process 1.739e-12 Highly Informative Direct
Biological Process (BP) polysaccharide catabolic process 5.835e-11 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0 Highly Informative Direct
Biological Process (BP) muscle fiber development 0.0004469 Highly Informative Direct
Biological Process (BP) protein localization to membrane 0 Highly Informative Direct
Biological Process (BP) muscle organ development 1.999e-06 Highly Informative Direct
Biological Process (BP) plasma membrane organization 0 Highly Informative Direct
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) signal release 2.809e-10 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 1.454e-10 Highly Informative Direct
Biological Process (BP) regulation of neurotransmitter levels 9.068e-10 Highly Informative Direct
Biological Process (BP) neurotransmitter transport 4.382e-14 Highly Informative Direct
Biological Process (BP) cellular carbohydrate catabolic process 0.0003163 Highly Informative Direct
Biological Process (BP) skeletal system development 4.474e-05 Highly Informative Direct
Biological Process (BP) phagocytosis 0 Highly Informative Direct
Biological Process (BP) chemotaxis 0 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 1.152e-13 Highly Informative Direct
Biological Process (BP) positive regulation of sequence-specific DNA binding transcription factor activity 4.309e-11 Highly Informative Direct
Biological Process (BP) protein ubiquitination 6.727e-11 Highly Informative Direct
Biological Process (BP) regulation of angiogenesis 2.946e-10 Highly Informative Direct
Biological Process (BP) immune response-regulating signaling pathway 5.252e-10 Highly Informative Direct
Biological Process (BP) regulation of multi-organism process 1.033e-09 Highly Informative Direct
Biological Process (BP) connective tissue development 3.759e-08 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 2.087e-07 Highly Informative Direct
Biological Process (BP) regulation of interleukin-1 production 2.284e-07 Highly Informative Direct
Biological Process (BP) negative regulation of secretion 5.898e-07 Highly Informative Direct
Biological Process (BP) multicellular organismal metabolic process 1.213e-06 Highly Informative Direct
Biological Process (BP) negative regulation of protein transport 1.503e-06 Highly Informative Direct
Biological Process (BP) axonogenesis 1.858e-06 Highly Informative Direct
Biological Process (BP) response to purine-containing compound 2.005e-06 Highly Informative Direct
Biological Process (BP) regulation of ion homeostasis 2.906e-06 Highly Informative Direct
Biological Process (BP) activation of immune response 3.255e-06 Highly Informative Direct
Biological Process (BP) response to alkaloid 4.46e-06 Highly Informative Direct
Biological Process (BP) peptidyl-serine modification 4.811e-06 Highly Informative Direct
Biological Process (BP) regulation of protein secretion 9.058e-06 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 1.86e-05 Highly Informative Direct
Biological Process (BP) negative regulation of cellular component movement 3.47e-05 Highly Informative Direct
Biological Process (BP) establishment or maintenance of cell polarity 0.0001117 Highly Informative Direct
Biological Process (BP) protein dephosphorylation 0.0001141 Highly Informative Direct
Biological Process (BP) calcium ion transport 0.0001815 Highly Informative Direct
Biological Process (BP) positive regulation of MAPK cascade 0.0002342 Highly Informative Direct
Biological Process (BP) activation of protein kinase activity 0.0003015 Highly Informative Direct
Biological Process (BP) response to drug 0.0003121 Highly Informative Direct
Biological Process (BP) regulation of peptidyl-tyrosine phosphorylation 0.0004906 Highly Informative Direct
Biological Process (BP) regulation of calcium ion transport 0.0005898 Highly Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.04356 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.2077 Highly Informative Inherited
Biological Process (BP) negative regulation of apoptotic process 1 Highly Informative Inherited
Biological Process (BP) positive regulation of protein transport 0.004816 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 0.003708 Highly Informative Inherited
Biological Process (BP) cellular response to organic cyclic compound 0.01906 Highly Informative Inherited
Biological Process (BP) ion transmembrane transport 0.1963 Highly Informative Inherited
Biological Process (BP) developmental growth 0.001355 Highly Informative Inherited
Biological Process (BP) mammary gland epithelium development 0.007131 Highly Informative Inherited
Biological Process (BP) epithelial tube morphogenesis 0.01675 Highly Informative Inherited
Biological Process (BP) morphogenesis of a branching epithelium 0.2669 Highly Informative Inherited
Biological Process (BP) cellular calcium ion homeostasis 0.003397 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.005403 Highly Informative Inherited
Biological Process (BP) symbiosis, encompassing mutualism through parasitism 0.002562 Highly Informative Inherited
Biological Process (BP) protein methylation 0.07779 Highly Informative Inherited
Biological Process (BP) histone modification 1 Highly Informative Inherited
Biological Process (BP) negative regulation of response to external stimulus 0.01588 Highly Informative Inherited
Biological Process (BP) regulation of behavior 0.003285 Highly Informative Inherited
Biological Process (BP) regulation of cellular component size 0.3094 Highly Informative Inherited
Biological Process (BP) regulation of cell projection organization 0.1639 Highly Informative Inherited
Biological Process (BP) regulation of neuron differentiation 0.198 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis 1 Highly Informative Inherited
Biological Process (BP) leukocyte migration 0.5932 Highly Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.7614 Highly Informative Inherited
Biological Process (BP) positive regulation of intracellular transport 0.00464 Highly Informative Inherited
Biological Process (BP) regulation of vesicle-mediated transport 0.00358 Highly Informative Inherited
Biological Process (BP) negative regulation of signal transduction 0.988 Highly Informative Inherited
Biological Process (BP) positive regulation of cell differentiation 0.3862 Highly Informative Inherited
Biological Process (BP) regulation of leukocyte differentiation 0.8571 Highly Informative Inherited
Biological Process (BP) positive regulation of cell activation 0.003676 Highly Informative Inherited
Biological Process (BP) regulation of lymphocyte activation 0.2222 Highly Informative Inherited
Biological Process (BP) ossification 0.0186 Highly Informative Inherited
Biological Process (BP) positive regulation of apoptotic process 0.07832 Highly Informative Inherited
Biological Process (BP) regulation of neuron apoptotic process 0.4764 Highly Informative Inherited
Biological Process (BP) negative regulation of endopeptidase activity 0.01327 Highly Informative Inherited
Biological Process (BP) regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.004425 Highly Informative Inherited
Biological Process (BP) photoreceptor cell differentiation 0.4553 Highly Informative Inherited
Biological Process (BP) regulation of intracellular protein transport 0.6003 Highly Informative Inherited
Biological Process (BP) regulation of nucleocytoplasmic transport 0.5748 Highly Informative Inherited
Biological Process (BP) regulation of protein localization to nucleus 0.0382 Highly Informative Inherited
Biological Process (BP) negative regulation of intracellular transport 0.002991 Highly Informative Inherited
Biological Process (BP) regulation of neurological system process 1 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.0164 Highly Informative Inherited
Biological Process (BP) glycosaminoglycan metabolic process 0.7386 Highly Informative Inherited
Biological Process (BP) telencephalon development 0.004563 Highly Informative Inherited
Biological Process (BP) multi-organism cellular process 0.08697 Highly Informative Inherited
Biological Process (BP) pattern specification process 1 Highly Informative Inherited
Biological Process (BP) pigment biosynthetic process 0.1989 Highly Informative Inherited
Biological Process (BP) stem cell development 1 Highly Informative Inherited
Biological Process (BP) regulation of cell adhesion 0.008053 Highly Informative Inherited
Biological Process (BP) cellular glucan metabolic process 0.2444 Highly Informative Inherited
Biological Process (BP) oligosaccharide metabolic process 0.3623 Highly Informative Inherited
Biological Process (BP) sensory perception 1 Highly Informative Inherited
Biological Process (BP) Golgi vesicle transport 0.1435 Highly Informative Inherited
Biological Process (BP) retina development in camera-type eye 0.0504 Highly Informative Inherited
Biological Process (BP) cardiac muscle tissue development 0.05428 Highly Informative Inherited
Biological Process (BP) heart morphogenesis 0.05291 Highly Informative Inherited
Biological Process (BP) regulation of blood pressure 0.1311 Highly Informative Inherited
Biological Process (BP) lymphocyte differentiation 0.8017 Highly Informative Inherited
Biological Process (BP) B cell activation 0.3145 Highly Informative Inherited
Biological Process (BP) leukocyte activation involved in immune response 0.07944 Highly Informative Inherited
Biological Process (BP) wound healing 0.4301 Highly Informative Inherited
Molecular Function (MF) binding 9.12e-06 Least Informative Direct
Molecular Function (MF) hydrolase activity 0.9843 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) structural molecule activity 0.0006415 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.8254 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) heterocyclic compound binding 1 Moderately Informative Inherited
Molecular Function (MF) organic cyclic compound binding 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) cation binding 0.03239 Moderately Informative Inherited
Molecular Function (MF) protein binding 0.8876 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0 Informative Direct
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 5.469e-14 Informative Direct
Molecular Function (MF) molecular transducer activity 3.281e-08 Informative Direct
Molecular Function (MF) receptor binding 6.504e-08 Informative Direct
Molecular Function (MF) carboxylic acid binding 8.074e-08 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.0001294 Informative Direct
Molecular Function (MF) inorganic cation transmembrane transporter activity 0.002689 Informative Inherited
Molecular Function (MF) peptidase regulator activity 0.007286 Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.03267 Informative Inherited
Molecular Function (MF) nucleoside-triphosphatase activity 1 Informative Inherited
Molecular Function (MF) enzyme activator activity 0.277 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 1 Informative Inherited
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.007407 Informative Inherited
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) phosphoric ester hydrolase activity 0.4141 Informative Inherited
Molecular Function (MF) peptidase activity 1 Informative Inherited
Molecular Function (MF) lipid binding 0.007214 Informative Inherited
Molecular Function (MF) channel regulator activity 6.021e-15 Highly Informative Direct
Molecular Function (MF) calcium ion binding 0 Highly Informative Direct
Molecular Function (MF) small conjugating protein ligase activity 0 Highly Informative Direct
Molecular Function (MF) modified amino acid binding 7.936e-14 Highly Informative Direct
Molecular Function (MF) sulfur compound binding 2.212e-10 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase regulator activity involved in apoptotic process 1.228e-08 Highly Informative Direct
Molecular Function (MF) cysteine-type endopeptidase inhibitor activity 2.357e-06 Highly Informative Direct
Molecular Function (MF) ion gated channel activity 4.261e-06 Highly Informative Direct
Molecular Function (MF) phosphoprotein phosphatase activity 3.794e-05 Highly Informative Direct
Molecular Function (MF) protein kinase regulator activity 0.0002788 Highly Informative Direct
Molecular Function (MF) ion channel activity 0.0003399 Highly Informative Direct
Molecular Function (MF) unfolded protein binding 0.0004639 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring hexosyl groups 0.02379 Highly Informative Inherited
Molecular Function (MF) glycosaminoglycan binding 0.6439 Highly Informative Inherited
Molecular Function (MF) protein complex binding 0.006035 Highly Informative Inherited
Molecular Function (MF) protein kinase activity 1 Highly Informative Inherited
Molecular Function (MF) metallopeptidase activity 0.01563 Highly Informative Inherited
Molecular Function (MF) endopeptidase activity 0.9917 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) membrane 0.0819 Least Informative Inherited
Cellular Component (CC) extracellular region 0 Moderately Informative Direct
Cellular Component (CC) endoplasmic reticulum 1.721e-12 Moderately Informative Direct
Cellular Component (CC) plasma membrane 8.217e-05 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 0.0006936 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0007644 Moderately Informative Direct
Cellular Component (CC) nuclear part 1 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 1 Moderately Informative Inherited
Cellular Component (CC) endomembrane system 0.002151 Moderately Informative Inherited
Cellular Component (CC) ribonucleoprotein complex 0.002409 Moderately Informative Inherited
Cellular Component (CC) organelle membrane 0.9776 Moderately Informative Inherited
Cellular Component (CC) extracellular matrix 0 Informative Direct
Cellular Component (CC) synapse 6.818e-12 Informative Direct
Cellular Component (CC) neuron part 4.908e-06 Informative Direct
Cellular Component (CC) cell leading edge 1.548e-05 Informative Direct
Cellular Component (CC) cell junction 4.449e-05 Informative Direct
Cellular Component (CC) endoplasmic reticulum membrane 7.864e-05 Informative Direct
Cellular Component (CC) nucleoplasm part 1 Informative Inherited
Cellular Component (CC) cell projection part 0.3913 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.2352 Informative Inherited
Cellular Component (CC) integral to membrane 0.8737 Informative Inherited
Cellular Component (CC) Golgi apparatus 0.01512 Informative Inherited
Cellular Component (CC) extracellular matrix part 0 Highly Informative Direct
Cellular Component (CC) proteinaceous extracellular matrix 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic mRNA processing body 0 Highly Informative Direct
Cellular Component (CC) synaptic membrane 1.769e-06 Highly Informative Direct
Cellular Component (CC) adherens junction 3.191e-06 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 6.549e-06 Highly Informative Direct
Cellular Component (CC) sarcoplasmic reticulum 7.3e-06 Highly Informative Direct
Cellular Component (CC) sarcolemma 0.0002871 Highly Informative Direct
Cellular Component (CC) lamellipodium 0.0003249 Highly Informative Direct
Cellular Component (CC) axon part 0.0006042 Highly Informative Direct
Cellular Component (CC) nuclear body 0.02344 Highly Informative Inherited
Cellular Component (CC) integral to plasma membrane 1 Highly Informative Inherited
Cellular Component (CC) cell-cell junction 1 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0Moderately InformativeDirect
Enzyme Commission (EC)Glycosyltransferases2.215e-12Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; involved in cellular an0.1378Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases0.07915Moderately InformativeInherited
Enzyme Commission (EC)Metalloendopeptidases0InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase1.837e-08InformativeDirect
Enzyme Commission (EC)Cellulose 1,4-beta-cellobiosidase (non-reducing en0Highly InformativeDirect
Enzyme Commission (EC)Bontoxilysin2.13e-13Highly InformativeDirect
Enzyme Commission (EC)Alpha-N-arabinofuranosidase0.0001267Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.5242Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.4164Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the retina0.07979InformativeInherited
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.1993InformativeInherited
Phenotypic Abnormality (PA)Vitreoretinal degeneration5.914e-05Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the epiphyses0.03729Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the femur0.04473Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.05126Least InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.7337Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.05004Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)neuron development variant4.145e-05InformativeDirect
Worm Phenotype (WP)muscle cell morphology variant0.004958InformativeInherited
Worm Phenotype (WP)axon guidance variant4.281e-06Highly InformativeDirect
Worm Phenotype (WP)axon morphology variant5.115e-06Highly InformativeDirect
Worm Phenotype (WP)myopodia present0.0004903Highly InformativeDirect
Worm Phenotype (WP)muscle arm development defective0.0006307Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)behavior defective0.0001769Moderately InformativeDirect
Fly Phenotype (FP)cell polarity defective9.978e-05InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)portion of tissue0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo1Least InformativeInherited
Xenopus ANatomical entity (XAN)portion of tissue1Least InformativeInherited
Xenopus ANatomical entity (XAN)mesoderm0.1534InformativeInherited
Xenopus ANatomical entity (XAN)trunk somite0.0005882Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)vascular leaf0.8477Least InformativeInherited