SUPERFAMILY 1.75 HMM library and genome assignments server

Cupredoxins superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Cupredoxin-like [ 49502] (2)
Superfamily:   Cupredoxins [ 49503] (7)
Families:   Plastocyanin/azurin-like [ 49504] (9)
  Nitrosocyanin [ 63392] (2)
  Periplasmic domain of cytochrome c oxidase subunit II [ 49541] (2)
  Multidomain cupredoxins [ 49550] (7)
  Ephrin ectodomain [ 74874] (2)
  Peptidylarginine deiminase Pad4, N-terminal domain [ 110107]
  SO1698-like [ 141095]


Superfamily statistics
Genomes (2,455) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 37,726 138,677 222
Proteins 20,755 98,499 151


Functional annotation
General category Processes_IC
Detailed category Ion metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.46941Least InformativeInherited
Biological Process (BP)single-organism cellular process0.10560.0000000001472Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.46581Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.062661Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.0035561Least InformativeInherited
Biological Process (BP)regulation of cellular process0.40481Least InformativeInherited
Biological Process (BP)response to stimulus0.0791Least InformativeInherited
Biological Process (BP)cellular component biogenesis0.26521Moderately InformativeInherited
Biological Process (BP)cellular macromolecule biosynthetic process0.063471Moderately InformativeInherited
Biological Process (BP)signal transduction0.00091960.9931Moderately InformativeInherited
Biological Process (BP)carbohydrate metabolic process0.023940.5856Moderately InformativeInherited
Biological Process (BP)enzyme linked receptor protein signaling pathway0.00000000078910.0000000002734InformativeDirect
Biological Process (BP)cell wall organization or biogenesis0.000008280.0001035InformativeDirect
Biological Process (BP)polysaccharide metabolic process0.00026920.0001121InformativeDirect
Biological Process (BP)cellular carbohydrate metabolic process0.00036140.02983InformativeInherited
Biological Process (BP)carbohydrate biosynthetic process0.0021660.00288InformativeInherited
Biological Process (BP)transmembrane receptor protein tyrosine kinase signaling pathway0.000000000053850.00000000000001071Highly InformativeDirect
Biological Process (BP)cell wall polysaccharide metabolic process0.00000013570.0001029Highly InformativeDirect
Biological Process (BP)cellular polysaccharide biosynthetic process0.00085410.001619Highly InformativeInherited
Biological Process (BP)cell wall macromolecule biosynthetic process0.090180.06546Highly InformativeInherited
Molecular Function (MF)binding0.20281Least InformativeInherited
Molecular Function (MF)oxidoreductase activity0.022350Moderately InformativeInherited
Molecular Function (MF)cation binding0.0038690.0004169Moderately InformativeInherited
Molecular Function (MF)receptor binding0.000036260.0000004302InformativeDirect
Molecular Function (MF)copper ion binding0.000000011170Highly InformativeDirect
Cellular Component (CC)membrane0.0000058940Least InformativeDirect
Cellular Component (CC)intrinsic component of membrane0.00000077471Moderately InformativeInherited
Cellular Component (CC)anchored component of membrane00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.0000000001472 Least Informative Direct
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) ion transport 0 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.7575 Moderately Informative Inherited
Biological Process (BP) regulation of phosphorus metabolic process 0.7897 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.7306 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) oxidation-reduction process 0.002797 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organonitrogen compound biosynthetic process 0.1971 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.004088 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.2361 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.2898 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.9931 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.5856 Moderately Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 0.0000000002734 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.0001035 Informative Direct
Biological Process (BP) polysaccharide metabolic process 0.0001121 Informative Direct
Biological Process (BP) monovalent inorganic cation transport 0 Informative Direct
Biological Process (BP) ion transmembrane transport 0 Informative Direct
Biological Process (BP) alpha-amino acid biosynthetic process 0.00004292 Informative Direct
Biological Process (BP) cellular modified amino acid metabolic process 0.0003903 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0.694 Informative Inherited
Biological Process (BP) regulation of body fluid levels 0.003046 Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 0.3825 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.6542 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.183 Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.964 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.4476 Informative Inherited
Biological Process (BP) regulation of cell development 0.234 Informative Inherited
Biological Process (BP) cation homeostasis 0.03339 Informative Inherited
Biological Process (BP) generation of neurons 0.2778 Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 0.035 Informative Inherited
Biological Process (BP) response to inorganic substance 0.005036 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.06272 Informative Inherited
Biological Process (BP) cellular carbohydrate metabolic process 0.02983 Informative Inherited
Biological Process (BP) regulation of nucleoside metabolic process 0.4129 Informative Inherited
Biological Process (BP) regulation of purine nucleotide metabolic process 0.6226 Informative Inherited
Biological Process (BP) regulation of cellular catabolic process 0.9581 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.1043 Informative Inherited
Biological Process (BP) organic hydroxy compound biosynthetic process 0.006401 Informative Inherited
Biological Process (BP) alcohol metabolic process 0.3867 Informative Inherited
Biological Process (BP) secondary metabolic process 0.01834 Informative Inherited
Biological Process (BP) nucleoside monophosphate metabolic process 0.1005 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 0.282 Informative Inherited
Biological Process (BP) purine ribonucleoside metabolic process 0.3949 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 0.4674 Informative Inherited
Biological Process (BP) phosphorylation 1 Informative Inherited
Biological Process (BP) carbohydrate biosynthetic process 0.00288 Informative Inherited
Biological Process (BP) metal ion transport 1 Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.00000000000001071 Highly Informative Direct
Biological Process (BP) cell wall polysaccharide metabolic process 0.0001029 Highly Informative Direct
Biological Process (BP) hydrogen ion transmembrane transport 0 Highly Informative Direct
Biological Process (BP) cellular modified amino acid biosynthetic process 0.00000003136 Highly Informative Direct
Biological Process (BP) oxidative phosphorylation 0.00000007055 Highly Informative Direct
Biological Process (BP) response to transition metal nanoparticle 0.0000001411 Highly Informative Direct
Biological Process (BP) transition metal ion transport 0.0000002225 Highly Informative Direct
Biological Process (BP) electron transport chain 0.0000002426 Highly Informative Direct
Biological Process (BP) regulation of peptidyl-tyrosine phosphorylation 0.000001436 Highly Informative Direct
Biological Process (BP) transition metal ion homeostasis 0.0000218 Highly Informative Direct
Biological Process (BP) coagulation 0.0003535 Highly Informative Direct
Biological Process (BP) phenylpropanoid metabolic process 0.0004521 Highly Informative Direct
Biological Process (BP) protein activation cascade 0.0007939 Highly Informative Direct
Biological Process (BP) negative regulation of nervous system development 0.02807 Highly Informative Inherited
Biological Process (BP) cellular polysaccharide biosynthetic process 0.001619 Highly Informative Inherited
Biological Process (BP) cell wall macromolecule biosynthetic process 0.06546 Highly Informative Inherited
Biological Process (BP) regulation of neuron projection development 0.009768 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0.00221 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.1586 Highly Informative Inherited
Biological Process (BP) regulation of Rho protein signal transduction 0.02542 Highly Informative Inherited
Biological Process (BP) regulation of Ras GTPase activity 0.07322 Highly Informative Inherited
Biological Process (BP) steroid biosynthetic process 0.001052 Highly Informative Inherited
Biological Process (BP) sterol metabolic process 0.001669 Highly Informative Inherited
Biological Process (BP) hemostasis 0.02431 Highly Informative Inherited
Biological Process (BP) wound healing 0.2004 Highly Informative Inherited
Biological Process (BP) regulation of cell adhesion 0.0154 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) cation binding 0.0004169 Moderately Informative Direct
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) receptor binding 0.0000004302 Informative Direct
Molecular Function (MF) electron carrier activity 0 Informative Direct
Molecular Function (MF) monovalent inorganic cation transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.00000001791 Informative Direct
Molecular Function (MF) peptidase activity 0.6213 Informative Inherited
Molecular Function (MF) copper ion binding 0 Highly Informative Direct
Molecular Function (MF) heme-copper terminal oxidase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor 0 Highly Informative Direct
Molecular Function (MF) hydrogen ion transmembrane transporter activity 0 Highly Informative Direct
Molecular Function (MF) serine hydrolase activity 0.002333 Highly Informative Inherited
Molecular Function (MF) endopeptidase activity 0.06524 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) protein complex 0 Least Informative Direct
Cellular Component (CC) plasma membrane part 0.7713 Moderately Informative Inherited
Cellular Component (CC) intrinsic component of membrane 1 Moderately Informative Inherited
Cellular Component (CC) respiratory chain 0 Informative Direct
Cellular Component (CC) intrinsic component of plasma membrane 0.03781 Informative Inherited
Cellular Component (CC) cell surface 0.6747 Informative Inherited
Cellular Component (CC) side of membrane 1 Informative Inherited
Cellular Component (CC) cell junction 0.2727 Informative Inherited
Cellular Component (CC) external encapsulating structure 0.02127 Informative Inherited
Cellular Component (CC) anchored component of membrane 0 Highly Informative Direct
Cellular Component (CC) respiratory chain complex IV 0 Highly Informative Direct
Cellular Component (CC) symplast 0.00001295 Highly Informative Direct
Cellular Component (CC) external side of plasma membrane 0.05549 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on a heme group of donors0Highly InformativeDirect
Enzyme Commission (EC)With oxygen as acceptor0Highly InformativeDirect
Enzyme Commission (EC)With a cytochrome as acceptor0Highly InformativeDirect
Enzyme Commission (EC)In linear amidines0.000000000000003021Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details) Document: DO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.01783Least InformativeInherited
Worm Phenotype (WP)cell death variant0.0001827Moderately InformativeDirect
Worm Phenotype (WP)cell corpse number variant0.000003888InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect

Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus DEvelopment stage (XDE)embryonic stage0.06086Least InformativeInherited
Xenopus DEvelopment stage (XDE)late tailbud stage0.0007707InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower0.05214Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure0.2844Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0.3724Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.4523Least InformativeInherited
Plant ANatomical entity (PAN)leaf0.9868Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon1Moderately InformativeInherited
Plant ANatomical entity (PAN)vascular system0.00000002953InformativeDirect
Plant ANatomical entity (PAN)fruit0.00009396InformativeDirect
Plant ANatomical entity (PAN)rosette leaf0.0002848InformativeDirect
Plant ANatomical entity (PAN)filament0Highly InformativeDirect
Plant ANatomical entity (PAN)leaf epidermis0.00000000000001474Highly InformativeDirect
Plant ANatomical entity (PAN)leaf vascular system0.0000000001398Highly InformativeDirect
Plant ANatomical entity (PAN)trichome0.0000000001899Highly InformativeDirect
Plant ANatomical entity (PAN)embryo sac cell0.005482Highly InformativeInherited
Plant structure DEvelopment stage (PDE)seedling development stage0.00000949InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0.13Moderately InformativeInherited
Enzyme Commission (EC)Acting on other nitrogenous compounds as donors0.00006867InformativeDirect
Enzyme Commission (EC)Acting on diphenols and related substances as donors0Highly InformativeDirect
Enzyme Commission (EC)With a cytochrome as acceptor0Highly InformativeDirect
Enzyme Commission (EC)Acting on a heme group of donors0Highly InformativeDirect
Enzyme Commission (EC)In linear amidines7.245e-16Highly InformativeDirect
Enzyme Commission (EC)Oxidizing metal ions0.02668Highly InformativeInherited

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)blood and blood forming organs0.001137Least InformativeInherited
Drugbank ATC_code (DB)antithrombotic agents1Moderately InformativeInherited
Drugbank ATC_code (DB)enzymes0.0000008124InformativeDirect
Drugbank ATC_code (DB)drotrecogin alfa (activated)0.00000003529Highly InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processDifferentiation0.0004201Moderately InformativeDirect
Biological processIon transport1Moderately InformativeInherited
Biological processElectron transport0InformativeDirect
Biological processNeurogenesis0.000000001456InformativeDirect
Biological processHemostasis0.000000001881InformativeDirect
Biological processAngiogenesis0.000002514InformativeDirect
Biological processRespiratory chain0Highly InformativeDirect
Biological processBlood coagulation0.00000000009958Highly InformativeDirect
Biological processNitrate assimilation0.00000008532Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentSecreted0.00000000000008931Moderately InformativeDirect
Cellular componentPlastid0.1224Moderately InformativeInherited
Cellular componentPeriplasm0InformativeDirect
Cellular componentMitochondrion inner membrane0InformativeDirect
Cellular componentGPI-anchor3.244e-16InformativeDirect
Cellular componentThylakoid0.0000004239InformativeDirect
Cellular componentChloroplast0.0000803InformativeDirect
Coding sequence diversityRNA editing0.000004672Moderately InformativeDirect
DiseaseTumor suppressor0.000214Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionCalcium0.00000005599Moderately InformativeDirect
Molecular functionIron1Moderately InformativeInherited
Molecular functionCopper0InformativeDirect
Molecular functionIron transport0.00000000007558Highly InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationSulfation0.0000001668InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)nitrogen metabolism0Moderately InformativeDirect
UniPathway (UP)energy metabolism0Moderately InformativeDirect
UniPathway (UP)one-carbon metabolism0.00000001448Moderately InformativeDirect
UniPathway (UP)nitrate reduction0InformativeDirect
UniPathway (UP)methylamine degradation0Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR008972 SSF49503 Protein matches
Abstract

Copper is one of the most prevalent transition metals in living organisms and its biological function is intimately related to its redox properties. Since free copper is toxic, even at very low concentrations, its homeostasis in living organisms is tightly controlled by subtle molecular mechanisms. In eukaryotes, before being transported inside the cell via the high-affinity copper transporters of the CTR family, the copper (II) ion is reduced to copper (I). In blue copper proteins such as Cupredoxin, the copper (I) ion form is stabilised by a constrained His2Cys coordination environment.

This entry represents cupredoxin proteins, as well as structural homologues to cupredoxin. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel [PubMed11867755]. Some of these proteins have lost the ability to bind copper. Proteins with a cupredoxin-type fold are found in the following family groups:

  • Mono-domain cupredoxins, such as amicyanin, plastocyanin, pseudoazurin, plantacyanin, azurin, auracyanin, rusticyanin, stellacyanin, and mavicyanin.
  • Multi-domain cupredoxins, such as nitrite reductase (2 domains of this fold), multicopper oxidase CueO, spore coat protein A, ascorbate oxidase (3 domains of this fold), laccase (3 domains of this fold), ceruloplamin (6 domains of this fold), and coagulation factor V.
  • Red copper protein nitrocyanin and the C-terminal of nitrous oxide reductase.
  • Quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.
  • Ephrin-a5 and ephrin-b2 ectodomain, which are related to cupredoxins but lack the metal-binding site.
  • The N-terminal domain of protein arginine deiminase Pad4, which is related to cupredoxin but lacks the metal-biding site.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 93 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Cupredoxins domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 93 hidden Markov models representing the Cupredoxins superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Disease Ontology (DO) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]