SUPERFAMILY 1.75 HMM library and genome assignments server

Immunoglobulin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Immunoglobulin-like beta-sandwich [ 48725] (28)
Superfamily:   Immunoglobulin [ 48726] (4)
Families:   V set domains (antibody variable domain-like) [ 48727] (32)
  C1 set domains (antibody constant domain-like) [ 48942] (23)
  C2 set domains [ 49142] (8)
  I set domains [ 49159] (38)


Superfamily statistics
Genomes (302) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 167,831 193,084 2,226
Proteins 60,572 85,490 1,346


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus00Least InformativeDirect
Biological Process (BP)single-organism cellular process00Least InformativeDirect
Biological Process (BP)protein metabolic process00Least InformativeDirect
Biological Process (BP)localization00Least InformativeDirect
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.82410Least InformativeInherited
Biological Process (BP)regulation of cellular process0.0000026960.3549Least InformativeInherited
Biological Process (BP)developmental process0.21920Least InformativeInherited
Biological Process (BP)multicellular organismal process0.2460Least InformativeInherited
Biological Process (BP)positive regulation of response to stimulus00Moderately InformativeDirect
Biological Process (BP)signal transduction00Moderately InformativeDirect
Biological Process (BP)immune system process00Moderately InformativeDirect
Biological Process (BP)regulation of protein metabolic process0.00000012720.00000000000001778Moderately InformativeDirect
Biological Process (BP)nervous system development0.00010190Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.0004520Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process10Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.000081280.5213Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process11Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.00000039140.0881Moderately InformativeInherited
Biological Process (BP)regulation of developmental process10Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.86770Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction11Moderately InformativeInherited
Biological Process (BP)response to organic substance0.56830.005477Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus11Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus10.2776Moderately InformativeInherited
Biological Process (BP)regulation of phosphate metabolic process10.00000000007639Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.36131Moderately InformativeInherited
Biological Process (BP)cell differentiation0.70780.0000001182Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process10.8417Moderately InformativeInherited
Biological Process (BP)regulation of localization10.2466Moderately InformativeInherited
Biological Process (BP)multi-organism process0.025690Moderately InformativeInherited
Biological Process (BP)organ development0.065630.000000001589Moderately InformativeInherited
Biological Process (BP)vesicle-mediated transport00InformativeDirect
Biological Process (BP)regulation of immune response00InformativeDirect
Biological Process (BP)immune response00InformativeDirect
Biological Process (BP)positive regulation of immune system process00InformativeDirect
Biological Process (BP)defense response00InformativeDirect
Biological Process (BP)immune effector process00.00000000000002119InformativeDirect
Biological Process (BP)biological adhesion0.000000000000021610InformativeDirect
Biological Process (BP)regulation of protein phosphorylation0.00000000000026620.00000001024InformativeDirect
Biological Process (BP)generation of neurons0.000000000068710InformativeDirect
Biological Process (BP)regulation of cell activation0.000000012580InformativeDirect
Biological Process (BP)sensory organ development0.00000021960.00000000002979InformativeDirect
Biological Process (BP)regulation of nervous system development0.0000030530.0000005533InformativeDirect
Biological Process (BP)negative regulation of cellular component organization0.0000049370.0002232InformativeDirect
Biological Process (BP)anatomical structure formation involved in morphogenesis0.000032540.00000009409InformativeDirect
Biological Process (BP)cardiovascular system development0.000034750.00000002904InformativeDirect
Biological Process (BP)response to bacterium0.00025140.000000000000003755InformativeDirect
Biological Process (BP)positive regulation of protein metabolic process0.012630InformativeInherited
Biological Process (BP)positive regulation of phosphate metabolic process0.086440.00000000002011InformativeInherited
Biological Process (BP)regulation of kinase activity0.0030831InformativeInherited
Biological Process (BP)regulation of cell proliferation10InformativeInherited
Biological Process (BP)regulation of ion transport0.083090.7438InformativeInherited
Biological Process (BP)regulation of cellular component movement0.39790.000000002013InformativeInherited
Biological Process (BP)regulation of response to external stimulus11InformativeInherited
Biological Process (BP)regulation of locomotion0.11890.0000000000033InformativeInherited
Biological Process (BP)negative regulation of signaling0.00023920.08164InformativeInherited
Biological Process (BP)negative regulation of cell communication0.00082320.1975InformativeInherited
Biological Process (BP)negative regulation of immune system process0.72020InformativeInherited
Biological Process (BP)negative regulation of response to stimulus11InformativeInherited
Biological Process (BP)organ morphogenesis0.00004310.001129InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.17070InformativeInherited
Biological Process (BP)positive regulation of signal transduction10.9564InformativeInherited
Biological Process (BP)regulation of intracellular protein kinase cascade0.15240.000001341InformativeInherited
Biological Process (BP)regulation of cell development0.0015970.04664InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.009290.00000000009222InformativeInherited
Biological Process (BP)positive regulation of transport10.6656InformativeInherited
Biological Process (BP)regulation of intracellular transport0.02390.8798InformativeInherited
Biological Process (BP)enzyme linked receptor protein signaling pathway11InformativeInherited
Biological Process (BP)regulation of immune effector process11InformativeInherited
Biological Process (BP)phagocytosis00Highly InformativeDirect
Biological Process (BP)leukocyte mediated immunity00Highly InformativeDirect
Biological Process (BP)humoral immune response00Highly InformativeDirect
Biological Process (BP)immune response-regulating cell surface receptor signaling pathway00Highly InformativeDirect
Biological Process (BP)positive regulation of cell activation00Highly InformativeDirect
Biological Process (BP)protein activation cascade00Highly InformativeDirect
Biological Process (BP)innate immune response00.00000000007691Highly InformativeDirect
Biological Process (BP)negative regulation of cellular component movement0.00000000029990.00001421Highly InformativeDirect
Biological Process (BP)angiogenesis0.00000000047740Highly InformativeDirect
Biological Process (BP)negative regulation of locomotion0.0000000012430.000003885Highly InformativeDirect
Biological Process (BP)regulation of mononuclear cell proliferation0.0000000021050Highly InformativeDirect
Biological Process (BP)positive regulation of MAPK cascade0.0000000047040Highly InformativeDirect
Biological Process (BP)immune response-activating signal transduction0.000000027750.00001666Highly InformativeDirect
Biological Process (BP)cell adhesion0.0000021190Highly InformativeDirect
Biological Process (BP)cell junction organization0.000010010.00000000004471Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte proliferation0.000051820.0000002265Highly InformativeDirect
Biological Process (BP)transmembrane receptor protein tyrosine kinase signaling pathway0.00013580Highly InformativeDirect
Biological Process (BP)cellular response to growth factor stimulus0.00020880.00000000000006398Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte mediated cytotoxicity0.00021980.0008847Highly InformativeDirect
Biological Process (BP)regulation of cell morphogenesis involved in differentiation0.00025030.0000000000005096Highly InformativeDirect
Biological Process (BP)positive regulation of lymphocyte mediated immunity0.00055320.0000001488Highly InformativeDirect
Biological Process (BP)regulation of peptidyl-tyrosine phosphorylation0.00058880.0000000000002989Highly InformativeDirect
Biological Process (BP)positive regulation of protein kinase activity0.61181Highly InformativeInherited
Biological Process (BP)eye morphogenesis0.00000001220.001588Highly InformativeInherited
Biological Process (BP)positive regulation of response to external stimulus11Highly InformativeInherited
Biological Process (BP)regulation of behavior11Highly InformativeInherited
Biological Process (BP)retina development in camera-type eye0.0000000043050.008204Highly InformativeInherited
Biological Process (BP)positive regulation of ion transport0.00055680.08302Highly InformativeInherited
Biological Process (BP)positive regulation of intracellular transport0.0040720.08537Highly InformativeInherited
Biological Process (BP)positive regulation of homeostatic process0.0047460.2424Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.00000000092220.1185Highly InformativeInherited
Biological Process (BP)regulation of ion homeostasis0.0000000041480.3158Highly InformativeInherited
Biological Process (BP)positive regulation of adaptive immune response10.00000154Highly InformativeInherited
Biological Process (BP)regulation of adaptive immune response based on somatic recombination of immune receptors built from0.0023760Highly InformativeInherited
Molecular Function (MF)binding00Least InformativeDirect
Molecular Function (MF)transferase activity10.01502Least InformativeInherited
Molecular Function (MF)anion binding0.051251Moderately InformativeInherited
Molecular Function (MF)structural molecule activity0.19320Moderately InformativeInherited
Molecular Function (MF)enzyme regulator activity0.025181Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.10920Moderately InformativeInherited
Molecular Function (MF)receptor activity0.000012830InformativeDirect
Molecular Function (MF)molecular transducer activity0.00013990InformativeDirect
Molecular Function (MF)amide binding0.00084520InformativeDirect
Molecular Function (MF)lipid binding0.22511InformativeInherited
Molecular Function (MF)receptor binding0.0010520.002019InformativeInherited
Molecular Function (MF)GTPase regulator activity0.000000022780.9175InformativeInherited
Molecular Function (MF)enzyme activator activity0.00000047670.9448InformativeInherited
Molecular Function (MF)phosphotransferase activity, alcohol group as acceptor0.0052290InformativeInherited
Molecular Function (MF)kinase activity0.035730InformativeInherited
Molecular Function (MF)antigen binding00Highly InformativeDirect
Molecular Function (MF)glycolipid binding0.0000000000000019840.000000003619Highly InformativeDirect
Molecular Function (MF)peptide binding0.00000013370Highly InformativeDirect
Molecular Function (MF)protein kinase activity0.00054140Highly InformativeDirect
Molecular Function (MF)phosphatidylinositol binding0.0000000000017160.3348Highly InformativeInherited
Molecular Function (MF)GTPase activator activity0.00000000000046040.274Highly InformativeInherited
Molecular Function (MF)small GTPase regulator activity0.0000000000028580.3449Highly InformativeInherited
Cellular Component (CC)membrane00Least InformativeDirect
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.73610.1114Least InformativeInherited
Cellular Component (CC)plasma membrane00Moderately InformativeDirect
Cellular Component (CC)vesicle00Moderately InformativeDirect
Cellular Component (CC)extracellular region part00Moderately InformativeDirect
Cellular Component (CC)cell projection0.060360Moderately InformativeInherited
Cellular Component (CC)extracellular membrane-bounded organelle00InformativeDirect
Cellular Component (CC)cell surface00InformativeDirect
Cellular Component (CC)neuron projection0.000000000048590InformativeDirect
Cellular Component (CC)extracellular space0.020241InformativeInherited
Cellular Component (CC)external side of plasma membrane00Highly InformativeDirect
Cellular Component (CC)receptor complex0.000000000000065370.00000000004548Highly InformativeDirect
Cellular Component (CC)growth cone0.0000000015570.0000148Highly InformativeDirect
Cellular Component (CC)perinuclear region of cytoplasm0.000003810.0003722Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.3549 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 0 Moderately Informative Direct
Biological Process (BP) signal transduction 0 Moderately Informative Direct
Biological Process (BP) immune system process 0 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.00000000000001778 Moderately Informative Direct
Biological Process (BP) nervous system development 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0 Moderately Informative Direct
Biological Process (BP) multi-organism process 0 Moderately Informative Direct
Biological Process (BP) organ development 0.000000001589 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.0000001182 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0 Moderately Informative Direct
Biological Process (BP) system process 0.00006079 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 0 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0.00000000007639 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.8417 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.2466 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.7486 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.5213 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.0881 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.005477 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.2776 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.002808 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.002088 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.06296 Moderately Informative Inherited
Biological Process (BP) vesicle-mediated transport 0 Informative Direct
Biological Process (BP) regulation of immune response 0 Informative Direct
Biological Process (BP) immune response 0 Informative Direct
Biological Process (BP) positive regulation of immune system process 0 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) immune effector process 0.00000000000002119 Informative Direct
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) regulation of protein phosphorylation 0.00000001024 Informative Direct
Biological Process (BP) generation of neurons 0 Informative Direct
Biological Process (BP) regulation of cell activation 0 Informative Direct
Biological Process (BP) sensory organ development 0.00000000002979 Informative Direct
Biological Process (BP) regulation of nervous system development 0.0000005533 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.0002232 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.00000009409 Informative Direct
Biological Process (BP) cardiovascular system development 0.00000002904 Informative Direct
Biological Process (BP) response to bacterium 0.000000000000003755 Informative Direct
Biological Process (BP) cytoskeleton organization 0.00000000001078 Informative Direct
Biological Process (BP) cellular component morphogenesis 0 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.00000000009222 Informative Direct
Biological Process (BP) positive regulation of protein metabolic process 0 Informative Direct
Biological Process (BP) positive regulation of phosphate metabolic process 0.00000000002011 Informative Direct
Biological Process (BP) regulation of locomotion 0.0000000000033 Informative Direct
Biological Process (BP) tissue morphogenesis 0.0004328 Informative Direct
Biological Process (BP) hematopoietic or lymphoid organ development 0.000000006325 Informative Direct
Biological Process (BP) regulation of intracellular protein kinase cascade 0.000001341 Informative Direct
Biological Process (BP) tube development 0.000004481 Informative Direct
Biological Process (BP) cellular response to endogenous stimulus 0 Informative Direct
Biological Process (BP) muscle structure development 0 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) phosphorylation 0 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.000000002013 Informative Direct
Biological Process (BP) negative regulation of immune system process 0 Informative Direct
Biological Process (BP) central nervous system development 0 Informative Direct
Biological Process (BP) cell projection organization 0 Informative Direct
Biological Process (BP) cellular component movement 0 Informative Direct
Biological Process (BP) growth 0 Informative Direct
Biological Process (BP) regulation of cell proliferation 0 Informative Direct
Biological Process (BP) muscle tissue development 0 Informative Direct
Biological Process (BP) localization of cell 0 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) response to cytokine stimulus 0 Informative Direct
Biological Process (BP) organelle assembly 0.000000000001226 Informative Direct
Biological Process (BP) regulation of defense response 0.000000000002398 Informative Direct
Biological Process (BP) regulation of mitotic cell cycle 0.000000000004146 Informative Direct
Biological Process (BP) response to wounding 0.000000004831 Informative Direct
Biological Process (BP) regulation of cytokine production 0.00000002486 Informative Direct
Biological Process (BP) regulation of cell cycle process 0.0000002358 Informative Direct
Biological Process (BP) gland development 0.0000003677 Informative Direct
Biological Process (BP) embryo development ending in birth or egg hatching 0.00002998 Informative Direct
Biological Process (BP) embryonic organ development 0.00004137 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.0001673 Informative Direct
Biological Process (BP) actin filament-based process 0.0003618 Informative Direct
Biological Process (BP) negative regulation of cell death 0.0003934 Informative Direct
Biological Process (BP) organelle localization 0.0004538 Informative Direct
Biological Process (BP) regulation of secretion 0.05594 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.9441 Informative Inherited
Biological Process (BP) positive regulation of nucleobase-containing compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.08164 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.1975 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 1 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.9564 Informative Inherited
Biological Process (BP) cellular membrane organization 0.2122 Informative Inherited
Biological Process (BP) cellular chemical homeostasis 0.9124 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 1 Informative Inherited
Biological Process (BP) regulation of protein localization 1 Informative Inherited
Biological Process (BP) regulation of system process 1 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.06944 Informative Inherited
Biological Process (BP) reproductive system development 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) organ morphogenesis 0.001129 Informative Inherited
Biological Process (BP) blood circulation 0.6137 Informative Inherited
Biological Process (BP) muscle system process 0.01637 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.5041 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.5707 Informative Inherited
Biological Process (BP) microtubule-based process 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) regulation of growth 0.3841 Informative Inherited
Biological Process (BP) synaptic transmission 1 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.8421 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.4801 Informative Inherited
Biological Process (BP) regulation of cell development 0.04664 Informative Inherited
Biological Process (BP) regulation of kinase activity 1 Informative Inherited
Biological Process (BP) regulation of lipid metabolic process 0.08695 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.1839 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.7512 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of transport 0.6656 Informative Inherited
Biological Process (BP) dephosphorylation 0.1984 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 1 Informative Inherited
Biological Process (BP) mitochondrion organization 1 Informative Inherited
Biological Process (BP) negative regulation of transport 0.8894 Informative Inherited
Biological Process (BP) regulation of ion transport 0.7438 Informative Inherited
Biological Process (BP) regulation of intracellular transport 0.8798 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.09159 Informative Inherited
Biological Process (BP) regulation of hormone levels 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure size 0.2735 Informative Inherited
Biological Process (BP) regulation of body fluid levels 0.1122 Informative Inherited
Biological Process (BP) multi-multicellular organism process 1 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.6387 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) sexual reproduction 0.5527 Informative Inherited
Biological Process (BP) nitrogen compound transport 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.9443 Informative Inherited
Biological Process (BP) secretion by cell 0.02512 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 1 Informative Inherited
Biological Process (BP) regulation of immune effector process 1 Informative Inherited
Biological Process (BP) cell cycle process 1 Informative Inherited
Biological Process (BP) mitotic cell cycle 1 Informative Inherited
Biological Process (BP) phagocytosis 0 Highly Informative Direct
Biological Process (BP) leukocyte mediated immunity 0 Highly Informative Direct
Biological Process (BP) humoral immune response 0 Highly Informative Direct
Biological Process (BP) immune response-regulating cell surface receptor signaling pathway 0 Highly Informative Direct
Biological Process (BP) positive regulation of cell activation 0 Highly Informative Direct
Biological Process (BP) protein activation cascade 0 Highly Informative Direct
Biological Process (BP) innate immune response 0.00000000007691 Highly Informative Direct
Biological Process (BP) negative regulation of cellular component movement 0.00001421 Highly Informative Direct
Biological Process (BP) angiogenesis 0 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 0.000003885 Highly Informative Direct
Biological Process (BP) regulation of mononuclear cell proliferation 0 Highly Informative Direct
Biological Process (BP) positive regulation of MAPK cascade 0 Highly Informative Direct
Biological Process (BP) immune response-activating signal transduction 0.00001666 Highly Informative Direct
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) cell junction organization 0.00000000004471 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte proliferation 0.0000002265 Highly Informative Direct
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0 Highly Informative Direct
Biological Process (BP) cellular response to growth factor stimulus 0.00000000000006398 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte mediated cytotoxicity 0.0008847 Highly Informative Direct
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0.0000000000005096 Highly Informative Direct
Biological Process (BP) positive regulation of lymphocyte mediated immunity 0.0000001488 Highly Informative Direct
Biological Process (BP) regulation of peptidyl-tyrosine phosphorylation 0.0000000000002989 Highly Informative Direct
Biological Process (BP) regulation of adaptive immune response based on somatic recombination of immune receptors built from 0 Highly Informative Direct
Biological Process (BP) regulation of neuron projection development 0 Highly Informative Direct
Biological Process (BP) mesenchyme development 0.000000000002906 Highly Informative Direct
Biological Process (BP) protein folding 0.00000000002724 Highly Informative Direct
Biological Process (BP) respiratory tube development 0.00000000000519 Highly Informative Direct
Biological Process (BP) regulation of calcium-mediated signaling 0.0000000005133 Highly Informative Direct
Biological Process (BP) skeletal system development 0.000001457 Highly Informative Direct
Biological Process (BP) protein phosphorylation 0 Highly Informative Direct
Biological Process (BP) renal system development 0.00000002298 Highly Informative Direct
Biological Process (BP) muscle organ development 0.00000000000009263 Highly Informative Direct
Biological Process (BP) respiratory system development 0.00002657 Highly Informative Direct
Biological Process (BP) chemotaxis 0 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0 Highly Informative Direct
Biological Process (BP) cell part morphogenesis 0.00000000835 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0 Highly Informative Direct
Biological Process (BP) regulation of T cell activation 0.00004468 Highly Informative Direct
Biological Process (BP) antigen processing and presentation 0 Highly Informative Direct
Biological Process (BP) ear development 0 Highly Informative Direct
Biological Process (BP) neuron projection development 0.00000000000001435 Highly Informative Direct
Biological Process (BP) developmental growth 0 Highly Informative Direct
Biological Process (BP) mammary gland epithelium development 0 Highly Informative Direct
Biological Process (BP) hair follicle development 0 Highly Informative Direct
Biological Process (BP) hemostasis 0 Highly Informative Direct
Biological Process (BP) cytokine-mediated signaling pathway 0 Highly Informative Direct
Biological Process (BP) regulation of striated muscle tissue development 0 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0 Highly Informative Direct
Biological Process (BP) regulation of mitosis 0 Highly Informative Direct
Biological Process (BP) cardiac muscle tissue development 0 Highly Informative Direct
Biological Process (BP) establishment of synaptic vesicle localization 0.000000000000001938 Highly Informative Direct
Biological Process (BP) stem cell proliferation 0.00000000000005424 Highly Informative Direct
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.0000000000001597 Highly Informative Direct
Biological Process (BP) actomyosin structure organization 0.0000000000009667 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0.000000000001752 Highly Informative Direct
Biological Process (BP) negative regulation of cell cycle 0.00000000002779 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 0.00000000005065 Highly Informative Direct
Biological Process (BP) cell growth 0.00000000006586 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 0.0000000003366 Highly Informative Direct
Biological Process (BP) heart morphogenesis 0.000000001632 Highly Informative Direct
Biological Process (BP) regulation of cell division 0.000000008066 Highly Informative Direct
Biological Process (BP) placenta development 0.000000009894 Highly Informative Direct
Biological Process (BP) ossification 0.00000001232 Highly Informative Direct
Biological Process (BP) sensory perception 0.00000001468 Highly Informative Direct
Biological Process (BP) limb morphogenesis 0.00000006995 Highly Informative Direct
Biological Process (BP) female pregnancy 0.0000001671 Highly Informative Direct
Biological Process (BP) cardiocyte differentiation 0.0000004481 Highly Informative Direct
Biological Process (BP) protein dephosphorylation 0.000001129 Highly Informative Direct
Biological Process (BP) positive regulation of adaptive immune response 0.00000154 Highly Informative Direct
Biological Process (BP) regulation of cytokine secretion 0.00003789 Highly Informative Direct
Biological Process (BP) coagulation 0.00008217 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 0.0001153 Highly Informative Direct
Biological Process (BP) morphogenesis of embryonic epithelium 0.0001456 Highly Informative Direct
Biological Process (BP) heart contraction 0.0002031 Highly Informative Direct
Biological Process (BP) spermatogenesis 0.0002071 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 0.0003942 Highly Informative Direct
Biological Process (BP) regulation of multicellular organism growth 0.0007057 Highly Informative Direct
Biological Process (BP) regulation of cell size 0.000741 Highly Informative Direct
Biological Process (BP) regulation of leukocyte differentiation 0.552 Highly Informative Inherited
Biological Process (BP) negative regulation of apoptotic process 0.02491 Highly Informative Inherited
Biological Process (BP) regulation of transmembrane transport 1 Highly Informative Inherited
Biological Process (BP) regulation of transporter activity 0.4948 Highly Informative Inherited
Biological Process (BP) regulation of DNA metabolic process 1 Highly Informative Inherited
Biological Process (BP) regulation of actin cytoskeleton organization 0.3583 Highly Informative Inherited
Biological Process (BP) regulation of muscle contraction 0.0429 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.022 Highly Informative Inherited
Biological Process (BP) response to drug 1 Highly Informative Inherited
Biological Process (BP) positive regulation of protein kinase activity 1 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 0.9756 Highly Informative Inherited
Biological Process (BP) positive regulation of programmed cell death 0.02202 Highly Informative Inherited
Biological Process (BP) regulation of reproductive process 0.2419 Highly Informative Inherited
Biological Process (BP) regulation of organ morphogenesis 0.02106 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.006315 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 0.003239 Highly Informative Inherited
Biological Process (BP) development of primary female sexual characteristics 0.5693 Highly Informative Inherited
Biological Process (BP) striated muscle contraction 1 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 1 Highly Informative Inherited
Biological Process (BP) spindle organization 0.07078 Highly Informative Inherited
Biological Process (BP) regulation of behavior 1 Highly Informative Inherited
Biological Process (BP) muscle fiber development 0.7481 Highly Informative Inherited
Biological Process (BP) regulation of synaptic transmission 0.6829 Highly Informative Inherited
Biological Process (BP) positive regulation of neurogenesis 1 Highly Informative Inherited
Biological Process (BP) positive regulation of cell cycle process 1 Highly Informative Inherited
Biological Process (BP) negative regulation of immune response 0.5164 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.924 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.896 Highly Informative Inherited
Biological Process (BP) exocytosis 1 Highly Informative Inherited
Biological Process (BP) membrane fusion 1 Highly Informative Inherited
Biological Process (BP) positive regulation of lipid metabolic process 0.01612 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.4762 Highly Informative Inherited
Biological Process (BP) cell fate commitment 1 Highly Informative Inherited
Biological Process (BP) retina development in camera-type eye 0.008204 Highly Informative Inherited
Biological Process (BP) negative regulation of leukocyte activation 0.2463 Highly Informative Inherited
Biological Process (BP) myeloid cell development 1 Highly Informative Inherited
Biological Process (BP) regulation of hormone secretion 1 Highly Informative Inherited
Biological Process (BP) negative regulation of protein transport 1 Highly Informative Inherited
Biological Process (BP) negative regulation of secretion 0.5372 Highly Informative Inherited
Biological Process (BP) post-embryonic organ development 1 Highly Informative Inherited
Biological Process (BP) post-embryonic development 1 Highly Informative Inherited
Biological Process (BP) stem cell development 1 Highly Informative Inherited
Biological Process (BP) regulation of toll-like receptor signaling pathway 0.001939 Highly Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.518 Highly Informative Inherited
Biological Process (BP) regulation of peptide transport 0.7822 Highly Informative Inherited
Biological Process (BP) embryonic organ morphogenesis 0.004276 Highly Informative Inherited
Biological Process (BP) leukocyte migration 1 Highly Informative Inherited
Biological Process (BP) establishment or maintenance of cell polarity 0.3355 Highly Informative Inherited
Biological Process (BP) regulation of cell adhesion 0.2298 Highly Informative Inherited
Biological Process (BP) glial cell differentiation 1 Highly Informative Inherited
Biological Process (BP) diencephalon development 0.6539 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 1 Highly Informative Inherited
Biological Process (BP) positive regulation of ion transport 0.08302 Highly Informative Inherited
Biological Process (BP) positive regulation of intracellular transport 0.08537 Highly Informative Inherited
Biological Process (BP) positive regulation of homeostatic process 0.2424 Highly Informative Inherited
Biological Process (BP) regulation of calcium ion transport 0.1185 Highly Informative Inherited
Biological Process (BP) regulation of ion homeostasis 0.3158 Highly Informative Inherited
Biological Process (BP) regulation of phospholipase activity 0.004313 Highly Informative Inherited
Biological Process (BP) pattern specification process 1 Highly Informative Inherited
Biological Process (BP) cellular hormone metabolic process 0.4235 Highly Informative Inherited
Biological Process (BP) hormone biosynthetic process 0.2535 Highly Informative Inherited
Biological Process (BP) cellular process involved in reproduction in multicellular organism 0.1955 Highly Informative Inherited
Biological Process (BP) female gamete generation 1 Highly Informative Inherited
Biological Process (BP) regulation of acute inflammatory response 0.5884 Highly Informative Inherited
Biological Process (BP) regulation of innate immune response 1 Highly Informative Inherited
Biological Process (BP) inflammatory response 1 Highly Informative Inherited
Biological Process (BP) leukocyte proliferation 0.03237 Highly Informative Inherited
Biological Process (BP) myeloid leukocyte activation 0.7814 Highly Informative Inherited
Biological Process (BP) leukocyte activation involved in immune response 1 Highly Informative Inherited
Biological Process (BP) multi-organism behavior 0.9482 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.001588 Highly Informative Inherited
Biological Process (BP) monoamine transport 0.02565 Highly Informative Inherited
Biological Process (BP) positive regulation of response to external stimulus 1 Highly Informative Inherited
Biological Process (BP) positive regulation of defense response 1 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) transferase activity 0.01502 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on ester bonds 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 1 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) amide binding 0 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0 Informative Direct
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) protein dimerization activity 0.0006383 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0009087 Informative Direct
Molecular Function (MF) lipid binding 1 Informative Inherited
Molecular Function (MF) carboxylic acid binding 0.409 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 1 Informative Inherited
Molecular Function (MF) sulfur compound binding 0.02735 Informative Inherited
Molecular Function (MF) metal ion transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) receptor binding 0.002019 Informative Inherited
Molecular Function (MF) GTPase regulator activity 0.9175 Informative Inherited
Molecular Function (MF) enzyme activator activity 0.9448 Informative Inherited
Molecular Function (MF) phosphoric ester hydrolase activity 0.5273