SUPERFAMILY 1.73 HMM library and genome assignments server


Phospholipase A2, PLA2 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (258)
Fold:   Phospholipase A2, PLA2 [ 48618]
  common core: 2 helices, disulfide-linked, and a calcium-binding loop
Superfamily:   Phospholipase A2, PLA2 [ 48619] (3)
Families:   Vertebrate phospholipase A2 [ 48623] (2)
  Insect phospholipase A2 [ 48620]
  Prokaryotic phospholipase A2 [ 63630]


Superfamily statistics
Genomes (199) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 1,256 1,200 86
Proteins 1,163 1,183 86


Functional annotation
General category Processes_IC
Detailed category Phospholipid metabolism and transport

Function annotation of SCOP domain superfamilies

Jump to [ Top of page · SCOP classification · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 46 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Phospholipase A2, PLA2 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 46 hidden Markov models representing the Phospholipase A2, PLA2 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]