SUPERFAMILY 1.75 HMM library and genome assignments server


Protein prenylyltransferase superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   Protein prenylyltransferase [ 48439]
Families:   Protein prenylyltransferase [ 48440] (2)


Superfamily statistics
Genomes (718) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 2,225 0 12
Proteins 2,171 0 12


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)protein metabolic process1.306e-101.042e-09Least InformativeDirect
Biological Process (BP)cellular macromolecule metabolic process3.636e-091.496e-10Least InformativeDirect
Biological Process (BP)cellular protein modification process4.233e-140Moderately InformativeDirect
Molecular Function (MF)binding0.087410.3562Least InformativeInherited
Molecular Function (MF)transferase activity, transferring alkyl or aryl (other than methyl) groups00InformativeDirect
Molecular Function (MF)enzyme binding8.296e-051.481e-07InformativeDirect
Molecular Function (MF)prenyltransferase activity00Highly InformativeDirect
Molecular Function (MF)Ras GTPase binding10Highly InformativeInherited
Cellular Component (CC)protein complex8.329e-104.095e-11Least InformativeDirect
Cellular Component (CC)cytoplasmic part6.824e-051.472e-07Least InformativeDirect
Cellular Component (CC)CAAX-protein geranylgeranyltransferase complex00Highly InformativeDirect
Cellular Component (CC)protein farnesyltransferase complex00Highly InformativeDirect
Cellular Component (CC)Rab-protein geranylgeranyltransferase complex2.689e-110Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 1.042e-09 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 1.496e-10 Least Informative Direct
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Molecular Function (MF) binding 0.3562 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring alkyl or aryl (other than methyl) groups 0 Informative Direct
Molecular Function (MF) enzyme binding 1.481e-07 Informative Direct
Molecular Function (MF) prenyltransferase activity 0 Highly Informative Direct
Molecular Function (MF) Ras GTPase binding 0 Highly Informative Direct
Cellular Component (CC) protein complex 4.095e-11 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1.472e-07 Least Informative Direct
Cellular Component (CC) CAAX-protein geranylgeranyltransferase complex 0 Highly Informative Direct
Cellular Component (CC) protein farnesyltransferase complex 0 Highly Informative Direct
Cellular Component (CC) Rab-protein geranylgeranyltransferase complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Protein geranylgeranyltransferase type II0Highly InformativeDirect

Document: EC annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
DomainRepeat0Least InformativeDirect
DomainLeucine-rich repeat1.258e-06InformativeDirect
DomainTPR repeat8.939e-08Highly InformativeDirect
Post-translational modificationTransferase2.5e-13Least InformativeDirect
Post-translational modificationAcetylation2.315e-05Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Yeast Phenotype (YP) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Protein prenylyltransferase domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Protein prenylyltransferase superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Yeast Phenotype (YP) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]