SUPERFAMILY 1.75 HMM library and genome assignments server


ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  MIF4G domain-like [ 100908] (5)
  PHAT domain [ 89129]
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  BC3264-like [ 109965] (2)
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  Diap1 N-terninal region-like [ 140830]
  Plakophilin 1 helical region [ 140833]
  RPA1889-like [ 158764]


Superfamily statistics
Genomes (2,484) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 139,023 186,320 107
Proteins 116,452 161,583 92


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.000018410Least InformativeDirect
Biological Process (BP)regulation of cellular process0.00040350.0004334Least InformativeDirect
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)localization0.015310Least InformativeInherited
Biological Process (BP)developmental process0.0074830.0002001Least InformativeInherited
Biological Process (BP)multicellular organismal process0.0820.06326Least InformativeInherited
Biological Process (BP)protein metabolic process0.15720.241Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.071290.1045Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.0010580Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)reproduction0.000028560.00004759Moderately InformativeDirect
Biological Process (BP)macromolecule localization0.00000000000000330Moderately InformativeDirect
Biological Process (BP)cellular localization0.00000000038950Moderately InformativeDirect
Biological Process (BP)organic substance transport0.000010440.00000005953Moderately InformativeDirect
Biological Process (BP)regulation of localization10.4574Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.14031Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.51461Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.0036030.02412Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.23350.006796Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.99311Moderately InformativeInherited
Biological Process (BP)cell differentiation0.24991Moderately InformativeInherited
Biological Process (BP)homeostatic process0.5011Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.53070Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)nervous system development0.26120.009979Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.17931Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.89011Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.91861Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.86620.1925Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.59740.9678Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.71030.02848Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process11Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.4991Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process11Moderately InformativeInherited
Biological Process (BP)tissue development0.52980.2352Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.62520.03009Moderately InformativeInherited
Biological Process (BP)protein transport0.00000000000000330InformativeDirect
Biological Process (BP)cell cycle process0.000004090InformativeDirect
Biological Process (BP)regulation of apoptotic process0.54690.589InformativeInherited
Biological Process (BP)positive regulation of signal transduction0.062461InformativeInherited
Biological Process (BP)organ morphogenesis0.75291InformativeInherited
Biological Process (BP)tissue morphogenesis0.160.001165InformativeInherited
Biological Process (BP)dephosphorylation0.019130.8777InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.91831InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.3930.08523InformativeInherited
Biological Process (BP)positive regulation of developmental process0.54310.6323InformativeInherited
Biological Process (BP)cell-cell signaling0.18920.009752InformativeInherited
Biological Process (BP)tube development0.13850.5075InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.33070.1807InformativeInherited
Biological Process (BP)reproductive system development0.23450.3914InformativeInherited
Biological Process (BP)organelle localization0.22370.8311InformativeInherited
Biological Process (BP)cytoplasmic transport0.0065380.01925InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.34571InformativeInherited
Biological Process (BP)regulation of intracellular transport0.00056770.008793InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.0011420.8913InformativeInherited
Biological Process (BP)sensory organ development0.013070.0357InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.62370.2401InformativeInherited
Biological Process (BP)embryonic morphogenesis0.044560.6218InformativeInherited
Biological Process (BP)protein localization to organelle0.041710.4127InformativeInherited
Biological Process (BP)regulation of establishment of protein localization0.00045471InformativeInherited
Biological Process (BP)leukocyte activation0.45680.2114InformativeInherited
Biological Process (BP)regulation of organelle organization0.46130InformativeInherited
Biological Process (BP)cardiovascular system development0.29630.7255InformativeInherited
Biological Process (BP)cellular component movement0.72490.2594InformativeInherited
Biological Process (BP)locomotion0.11990.000236InformativeInherited
Biological Process (BP)localization of cell0.37391InformativeInherited
Biological Process (BP)central nervous system development0.43350.5079InformativeInherited
Biological Process (BP)regulation of nervous system development0.1610.3848InformativeInherited
Biological Process (BP)regulation of cell development0.11580.02576InformativeInherited
Biological Process (BP)generation of neurons0.20431InformativeInherited
Biological Process (BP)negative regulation of developmental process0.95221InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.0016310.8381InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.0003460.9007InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.19650.00000009265InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.44760.9697InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.0027210.0000000193InformativeInherited
Biological Process (BP)cellular component morphogenesis0.93981InformativeInherited
Biological Process (BP)regulation of cell proliferation11InformativeInherited
Biological Process (BP)epithelium development0.013690.0005421InformativeInherited
Biological Process (BP)embryo development ending in birth or egg hatching0.054510.00787InformativeInherited
Biological Process (BP)regulation of cell cycle process0.01060.0006223InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.31920.0000162InformativeInherited
Biological Process (BP)DNA damage checkpoint0.0007040.00004441Highly InformativeDirect
Biological Process (BP)mRNA catabolic process0.00079550.00000000287Highly InformativeDirect
Biological Process (BP)establishment or maintenance of cell polarity0.00046880.0000000007418Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)regulation of intracellular protein transport0.000004170.0000005455Highly InformativeDirect
Biological Process (BP)protein localization to nucleus0.00000012470Highly InformativeDirect
Biological Process (BP)protein targeting to nucleus0.00000000036810Highly InformativeDirect
Biological Process (BP)regulation of nucleocytoplasmic transport0.00000019430.00000001591Highly InformativeDirect
Biological Process (BP)eye morphogenesis0.00045550.000005063Highly InformativeDirect
Biological Process (BP)nuclear import00Highly InformativeDirect
Biological Process (BP)stem cell proliferation0.00000058130.000004144Highly InformativeDirect
Biological Process (BP)epithelial tube formation0.000042070.0000000001207Highly InformativeDirect
Biological Process (BP)regulation of protein localization to nucleus0.00000052380.000001197Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.00047330.08893Highly InformativeInherited
Biological Process (BP)renal system development0.19610.4039Highly InformativeInherited
Biological Process (BP)protein dephosphorylation0.00010650.07206Highly InformativeInherited
Biological Process (BP)epithelial cell development0.07340.487Highly InformativeInherited
Biological Process (BP)hair follicle development0.064120.1412Highly InformativeInherited
Biological Process (BP)regulation of reproductive process0.026430.003342Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.061150.1993Highly InformativeInherited
Biological Process (BP)cell fate commitment0.076231Highly InformativeInherited
Biological Process (BP)respiratory tube development0.019860.7812Highly InformativeInherited
Biological Process (BP)mesenchyme development0.0069390.737Highly InformativeInherited
Biological Process (BP)respiratory system development0.030540.01214Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.0011520.672Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.010960.003946Highly InformativeInherited
Biological Process (BP)tissue homeostasis0.078541Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.012331Highly InformativeInherited
Biological Process (BP)T cell differentiation0.033240.05672Highly InformativeInherited
Biological Process (BP)regulation of protein depolymerization0.0074430Highly InformativeInherited
Biological Process (BP)telencephalon development0.10570.0005859Highly InformativeInherited
Biological Process (BP)glial cell differentiation0.18460.1208Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.90421Highly InformativeInherited
Biological Process (BP)pattern specification process0.26890.5715Highly InformativeInherited
Biological Process (BP)peptidyl-lysine modification0.0000000078880.001025Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.00000000039850.001833Highly InformativeInherited
Biological Process (BP)neural precursor cell proliferation0.0030180.00002909Highly InformativeInherited
Biological Process (BP)regulation of microtubule polymerization or depolymerization0.49010.02108Highly InformativeInherited
Biological Process (BP)negative regulation of protein complex disassembly0.028120.000000000000001922Highly InformativeInherited
Biological Process (BP)negative regulation of cytoskeleton organization0.1770.0000865Highly InformativeInherited
Biological Process (BP)regulation of organ morphogenesis0.015380.2859Highly InformativeInherited
Biological Process (BP)regulation of neural precursor cell proliferation0.0027850.0000857Highly InformativeInherited
Biological Process (BP)positive regulation of cell differentiation0.1490.03716Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.011060.006797Highly InformativeInherited
Molecular Function (MF)binding0.00000045450.000000000000006797Least InformativeDirect
Molecular Function (MF)enzyme regulator activity0.000010230.000000000000001558Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.81910.8119Moderately InformativeInherited
Molecular Function (MF)amide binding0.10360.892InformativeInherited
Molecular Function (MF)protein transporter activity0.000000004590Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity0.0000000000035130.000000473Highly InformativeDirect
Molecular Function (MF)monooxygenase activity0.00000000013710.2625Highly InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge0.00000036520.8098Highly InformativeInherited
Molecular Function (MF)peptide binding0.028250.4341Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle0.000000012350Least InformativeDirect
Cellular Component (CC)membrane0.98070.6368Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.052560.0000000000657Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.042380.0000001202Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.49050.5985Least InformativeInherited
Cellular Component (CC)nuclear part0.000000015140.000000000005744Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.63491Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cell projection0.054990.09333Moderately InformativeInherited
Cellular Component (CC)cytoskeleton10.1127Moderately InformativeInherited
Cellular Component (CC)organelle membrane10.001826Moderately InformativeInherited
Cellular Component (CC)endomembrane system0.42170Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.99760.2774Moderately InformativeInherited
Cellular Component (CC)microtubule cytoskeleton0.000010920.0000000000004107InformativeDirect
Cellular Component (CC)integral to membrane0.63931InformativeInherited
Cellular Component (CC)cell-cell junction0.23420.001581InformativeInherited
Cellular Component (CC)vacuolar part0.007630.005849InformativeInherited
Cellular Component (CC)nuclear envelope0.020110.000000000009127InformativeInherited
Cellular Component (CC)trans-Golgi network0.00021770Highly InformativeDirect
Cellular Component (CC)protein serine/threonine phosphatase complex00Highly InformativeDirect
Cellular Component (CC)lateral plasma membrane0.0004410.000482Highly InformativeDirect
Cellular Component (CC)CCR4-NOT complex0.000000015090.0003695Highly InformativeDirect
Cellular Component (CC)pore complex0.000089340Highly InformativeDirect
Cellular Component (CC)SWI/SNF superfamily-type complex0.0014150.4455Highly InformativeInherited
Cellular Component (CC)spindle0.056410.000002989Highly InformativeInherited
Cellular Component (CC)microvillus0.011680.4172Highly InformativeInherited
Cellular Component (CC)cell projection membrane0.0070240.0000003797Highly InformativeInherited
Cellular Component (CC)proteasome complex0.250Highly InformativeInherited
Cellular Component (CC)apical junction complex0.0011220.0007487Highly InformativeInherited
Cellular Component (CC)adherens junction11Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)