SUPERFAMILY 1.75 HMM library and genome assignments server

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ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  MIF4G domain-like [ 100908] (5)
  PHAT domain [ 89129]
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  BC3264-like [ 109965] (2)
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  Diap1 N-terninal region-like [ 140830]
  Plakophilin 1 helical region [ 140833]
  RPA1889-like [ 158764]


Superfamily statistics
Genomes (2,494) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 144,077 186,320 107
Proteins 120,698 161,583 92


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.00001460Least InformativeDirect
Biological Process (BP)regulation of cellular process0.00024640.0001828Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.00028960Least InformativeDirect
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)localization0.012290Least InformativeInherited
Biological Process (BP)developmental process0.0063450.0000009676Least InformativeInherited
Biological Process (BP)multicellular organismal process0.069650.002151Least InformativeInherited
Biological Process (BP)protein metabolic process0.17330.09154Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.080840.0283Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)response to stimulus11Least InformativeInherited
Biological Process (BP)reproduction0.000026550.000003245Moderately InformativeDirect
Biological Process (BP)macromolecule localization0.0000000000000032580Moderately InformativeDirect
Biological Process (BP)cellular localization0.0000000003890Moderately InformativeDirect
Biological Process (BP)organic substance transport0.0000079950.0000001039Moderately InformativeDirect
Biological Process (BP)regulation of localization10.5169Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)immune system process0.98921Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.54021Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.0035780.005448Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus11Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.96641Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.20160.00706Moderately InformativeInherited
Biological Process (BP)cell differentiation0.251Moderately InformativeInherited
Biological Process (BP)regulation of biological quality10.2581Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.47140Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)nervous system development0.25560.006692Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.17671Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.15541Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.91441Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.93821Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.87920.2272Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.58470.979Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.94351Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.70540.01012Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.47351Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process11Moderately InformativeInherited
Biological Process (BP)tissue development0.54050.2481Moderately InformativeInherited
Biological Process (BP)cellular response to stress0.61850.00908Moderately InformativeInherited
Biological Process (BP)protein transport0.0000000000000032580InformativeDirect
Biological Process (BP)cell cycle process0.0000042260InformativeDirect
Biological Process (BP)regulation of apoptotic process0.5550.5549InformativeInherited
Biological Process (BP)positive regulation of signal transduction0.06751InformativeInherited
Biological Process (BP)organ morphogenesis0.76881InformativeInherited
Biological Process (BP)tissue morphogenesis0.16440.001842InformativeInherited
Biological Process (BP)dephosphorylation0.02190.8286InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.90921InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.37810.0382InformativeInherited
Biological Process (BP)positive regulation of developmental process0.51490.5767InformativeInherited
Biological Process (BP)tube development0.13680.5223InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.34330.1314InformativeInherited
Biological Process (BP)reproductive system development0.24370.248InformativeInherited
Biological Process (BP)organelle localization0.23840.8314InformativeInherited
Biological Process (BP)cytoplasmic transport0.0066020.0174InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.34961InformativeInherited
Biological Process (BP)regulation of intracellular transport0.00062120.01109InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.0014110.8705InformativeInherited
Biological Process (BP)sensory organ development0.013460.03848InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.64560.2801InformativeInherited
Biological Process (BP)embryonic morphogenesis0.043810.6697InformativeInherited
Biological Process (BP)protein localization to organelle0.036740.296InformativeInherited
Biological Process (BP)regulation of establishment of protein localization0.00044211InformativeInherited
Biological Process (BP)leukocyte activation0.44510.1674InformativeInherited
Biological Process (BP)regulation of system process0.4771InformativeInherited
Biological Process (BP)regulation of organelle organization0.44330InformativeInherited
Biological Process (BP)cardiovascular system development0.29960.75InformativeInherited
Biological Process (BP)cellular component movement0.69390.2308InformativeInherited
Biological Process (BP)locomotion0.10950.00005628InformativeInherited
Biological Process (BP)localization of cell0.35141InformativeInherited
Biological Process (BP)central nervous system development0.42810.5825InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.00066110.781InformativeInherited
Biological Process (BP)regulation of cell development0.11360.007626InformativeInherited
Biological Process (BP)regulation of nervous system development0.15970.1378InformativeInherited
Biological Process (BP)generation of neurons0.20641InformativeInherited
Biological Process (BP)negative regulation of developmental process0.93161InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.00047980.8988InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.17610.000000392InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.44820.8782InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.002230.000000004167InformativeInherited
Biological Process (BP)cellular component morphogenesis0.95661InformativeInherited
Biological Process (BP)regulation of cell proliferation11InformativeInherited
Biological Process (BP)epithelium development0.012780.000719InformativeInherited
Biological Process (BP)embryo development ending in birth or egg hatching0.050950.006752InformativeInherited
Biological Process (BP)response to DNA damage stimulus0.31440.00002892InformativeInherited
Biological Process (BP)regulation of cell cycle process0.00440.0005287InformativeInherited
Biological Process (BP)DNA damage checkpoint0.00065440.00004112Highly InformativeDirect
Biological Process (BP)mRNA catabolic process0.00090860.000000001638Highly InformativeDirect
Biological Process (BP)establishment or maintenance of cell polarity0.00040560.0000000002904Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification0.000000030010.0008276Highly InformativeDirect
Biological Process (BP)regulation of intracellular protein transport0.0000039110.0000003149Highly InformativeDirect
Biological Process (BP)protein localization to nucleus0.00000015880Highly InformativeDirect
Biological Process (BP)protein targeting to nucleus0.00000000041670Highly InformativeDirect
Biological Process (BP)regulation of nucleocytoplasmic transport0.00000018740.000000009053Highly InformativeDirect
Biological Process (BP)eye morphogenesis0.00044630.000001641Highly InformativeDirect
Biological Process (BP)nuclear import00Highly InformativeDirect
Biological Process (BP)stem cell proliferation0.00000057730.000003216Highly InformativeDirect
Biological Process (BP)epithelial tube formation0.000038730.00000000004874Highly InformativeDirect
Biological Process (BP)regulation of protein localization to nucleus0.0000004590.0000007223Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.00045510.07519Highly InformativeInherited
Biological Process (BP)renal system development0.19160.4205Highly InformativeInherited
Biological Process (BP)protein dephosphorylation0.000087260.05142Highly InformativeInherited
Biological Process (BP)epithelial cell development0.069070.5352Highly InformativeInherited
Biological Process (BP)hair follicle development0.061010.1539Highly InformativeInherited
Biological Process (BP)regulation of reproductive process0.024060.0004439Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.058770.1628Highly InformativeInherited
Biological Process (BP)cell fate commitment0.073690.9995Highly InformativeInherited
Biological Process (BP)respiratory tube development0.019270.7849Highly InformativeInherited
Biological Process (BP)mesenchyme development0.0070930.7745Highly InformativeInherited
Biological Process (BP)respiratory system development0.029250.01164Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.0011430.7149Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.010460.00249Highly InformativeInherited
Biological Process (BP)cell junction organization0.0041740.00000001212Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.011781Highly InformativeInherited
Biological Process (BP)T cell differentiation0.031830.05966Highly InformativeInherited
Biological Process (BP)regulation of ion homeostasis0.11050.08104Highly InformativeInherited
Biological Process (BP)telencephalon development0.10320.000006128Highly InformativeInherited
Biological Process (BP)glial cell differentiation0.17790.1652Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.87761Highly InformativeInherited
Biological Process (BP)pattern specification process0.28120.4638Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process0.00000000064050.001677Highly InformativeInherited
Biological Process (BP)neural precursor cell proliferation0.0030130.00002165Highly InformativeInherited
Biological Process (BP)regulation of microtubule polymerization or depolymerization0.46930.026Highly InformativeInherited
Biological Process (BP)regulation of protein complex disassembly0.069920.0000000000003619Highly InformativeInherited
Biological Process (BP)negative regulation of cytoskeleton organization0.17340.0001345Highly InformativeInherited
Biological Process (BP)cell morphogenesis involved in differentiation0.4751Highly InformativeInherited
Biological Process (BP)regulation of organ morphogenesis0.014690.2973Highly InformativeInherited
Biological Process (BP)regulation of neural precursor cell proliferation0.0026530.00004165Highly InformativeInherited
Biological Process (BP)positive regulation of neurogenesis0.1540.3565Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.01050.005219Highly InformativeInherited
Molecular Function (MF)binding0.00000092290Least InformativeDirect
Molecular Function (MF)enzyme regulator activity0.0000086340Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.79890.6908Moderately InformativeInherited
Molecular Function (MF)amide binding0.096380.8908InformativeInherited
Molecular Function (MF)protein transporter activity0.0000000029030Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity0.000000000003310.000000453Highly InformativeDirect
Molecular Function (MF)monooxygenase activity0.0000000002890.2593Highly InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge0.00000058580.7895Highly InformativeInherited
Molecular Function (MF)peptide binding0.027010.3722Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle0.0000000088020Least InformativeDirect
Cellular Component (CC)membrane10.2826Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.05560.0000000001627Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.036240.00000001098Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.54610.5401Least InformativeInherited
Cellular Component (CC)nuclear part0.0000000083930.00000000002116Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.60521Moderately InformativeInherited
Cellular Component (CC)plasma membrane11Moderately InformativeInherited
Cellular Component (CC)cell projection0.052080.0703Moderately InformativeInherited
Cellular Component (CC)cytoskeleton10.1514Moderately InformativeInherited
Cellular Component (CC)organelle membrane10.0004424Moderately InformativeInherited
Cellular Component (CC)microtubule cytoskeleton0.0000093840.00000000000006564InformativeDirect
Cellular Component (CC)integral to membrane0.611InformativeInherited
Cellular Component (CC)cell junction0.011490InformativeInherited
Cellular Component (CC)vacuolar part0.0076480.002151InformativeInherited
Cellular Component (CC)trans-Golgi network0.00020070Highly InformativeDirect
Cellular Component (CC)protein serine/threonine phosphatase complex00Highly InformativeDirect
Cellular Component (CC)pore complex0.000095710Highly InformativeDirect
Cellular Component (CC)spindle0.059240.000001758Highly InformativeInherited
Cellular Component (CC)cell projection membrane0.0068540.0000008783Highly InformativeInherited
Cellular Component (CC)adherens junction11Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)