SUPERFAMILY 1.75 HMM library and genome assignments server


ARM repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   alpha-alpha superhelix [ 48370] (24)
Superfamily:   ARM repeat [ 48371] (23)
Families:   Armadillo repeat [ 48372] (6)
  Clathrin adaptor core protein [ 74771] (2)
  HEAT repeat [ 48385] (2)
  MIF4G domain-like [ 100908] (5)
  PHAT domain [ 89129]
  Mo25 protein [ 101407]
  Leukotriene A4 hydrolase C-terminal domain [ 63608]
  Clathrin heavy chain proximal leg segment [ 48390]
  Clathrin heavy-chain linker domain [ 48393]
  Leucine-rich repeat variant [ 48396]
  Phoshoinositide 3-kinase (PI3K) helical domain [ 48399]
  Pumilio repeat [ 63611]
  Regulatory subunit H of the V-type ATPase [ 63614]
  PBS lyase HEAT-like repeat [ 101410] (2)
  BC3264-like [ 109965] (2)
  Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [ 109968]
  Exportin HEAT-like repeat [ 117002]
  B56-like [ 140819]
  HspBP1 domain [ 140822]
  GUN4-associated domain [ 140825] (2)
  Diap1 N-terninal region-like [ 140830]
  Plakophilin 1 helical region [ 140833]
  RPA1889-like [ 158764]


Superfamily statistics
Genomes (2,449) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 129,190 118,822 107
Proteins 108,316 101,779 92


Functional annotation
General category General
Detailed category General

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process7.618e-060Least InformativeDirect
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process11Least InformativeInherited
Biological Process (BP)regulation of cellular process0.00044040.001699Least InformativeInherited
Biological Process (BP)localization0.0081240Least InformativeInherited
Biological Process (BP)developmental process0.0078353.713e-05Least InformativeInherited
Biological Process (BP)multicellular organismal process0.079560.01797Least InformativeInherited
Biological Process (BP)protein metabolic process0.091480.07279Least InformativeInherited
Biological Process (BP)biosynthetic process11Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.045020.01759Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.0011540Least InformativeInherited
Biological Process (BP)reproduction1.442e-051.206e-06Moderately InformativeDirect
Biological Process (BP)macromolecule localization00Moderately InformativeDirect
Biological Process (BP)cellular localization6.479e-110Moderately InformativeDirect
Biological Process (BP)organic substance transport3.281e-061.549e-07Moderately InformativeDirect
Biological Process (BP)regulation of programmed cell death0.00039821Moderately InformativeInherited
Biological Process (BP)regulation of localization10.7989Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process11Moderately InformativeInherited
Biological Process (BP)immune system process11Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.46751Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction0.0017670.008293Moderately InformativeInherited
Biological Process (BP)positive regulation of response to stimulus11Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process0.29380.007584Moderately InformativeInherited
Biological Process (BP)regulation of developmental process0.97671Moderately InformativeInherited
Biological Process (BP)cell differentiation0.26871Moderately InformativeInherited
Biological Process (BP)homeostatic process0.41481Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.54022.779e-14Moderately InformativeInherited
Biological Process (BP)organ development11Moderately InformativeInherited
Biological Process (BP)nervous system development0.17630.009018Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.21581Moderately InformativeInherited
Biological Process (BP)cellular protein modification process0.15571Moderately InformativeInherited
Biological Process (BP)single-organism biosynthetic process0.84711Moderately InformativeInherited
Biological Process (BP)organonitrogen compound biosynthetic process0.86531Moderately InformativeInherited
Biological Process (BP)anatomical structure morphogenesis0.78860.6586Moderately InformativeInherited
Biological Process (BP)RNA metabolic process0.70690.9545Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.71840.01357Moderately InformativeInherited
Biological Process (BP)organic cyclic compound catabolic process0.98141Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process0.54391Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process11Moderately InformativeInherited
Biological Process (BP)tissue development0.41650.4522Moderately InformativeInherited
Biological Process (BP)protein transport1.604e-150InformativeDirect
Biological Process (BP)cell cycle process3.715e-060InformativeDirect
Biological Process (BP)positive regulation of signal transduction0.070331InformativeInherited
Biological Process (BP)regulation of apoptotic signaling pathway0.0075920.5413InformativeInherited
Biological Process (BP)positive regulation of cell proliferation11InformativeInherited
Biological Process (BP)regulation of protein localization0.0013234.679e-07InformativeInherited
Biological Process (BP)organ morphogenesis0.68711InformativeInherited
Biological Process (BP)tissue morphogenesis0.11020.01812InformativeInherited
Biological Process (BP)dephosphorylation0.01720.7994InformativeInherited
Biological Process (BP)positive regulation of multicellular organismal process0.87741InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.43240.4117InformativeInherited
Biological Process (BP)positive regulation of developmental process0.54891InformativeInherited
Biological Process (BP)cell-cell signaling0.18880.0006945InformativeInherited
Biological Process (BP)reproductive structure development0.32110.6219InformativeInherited
Biological Process (BP)organelle localization0.20180.7679InformativeInherited
Biological Process (BP)cytoplasmic transport0.0087470.05268InformativeInherited
Biological Process (BP)hematopoietic or lymphoid organ development0.59911InformativeInherited
Biological Process (BP)regulation of intracellular transport0.00039590.04775InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00084080.8238InformativeInherited
Biological Process (BP)sensory organ development0.0094250.01084InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.58850.3578InformativeInherited
Biological Process (BP)embryonic morphogenesis0.033090.4476InformativeInherited
Biological Process (BP)protein localization to organelle0.04490.4936InformativeInherited
Biological Process (BP)cell activation0.87121InformativeInherited
Biological Process (BP)regulation of organelle organization0.49251.932e-15InformativeInherited
Biological Process (BP)cardiovascular system development0.25560.7236InformativeInherited
Biological Process (BP)cellular component movement0.64560.6274InformativeInherited
Biological Process (BP)locomotion0.089970.001767InformativeInherited
Biological Process (BP)localization of cell0.33911InformativeInherited
Biological Process (BP)central nervous system development0.38340.6656InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.0047510.7951InformativeInherited
Biological Process (BP)regulation of nervous system development0.12430.2013InformativeInherited
Biological Process (BP)regulation of cell development0.12020.1622InformativeInherited
Biological Process (BP)generation of neurons0.1971InformativeInherited
Biological Process (BP)negative regulation of developmental process0.90430.9914InformativeInherited
Biological Process (BP)alpha-amino acid biosynthetic process0.00026090.8438InformativeInherited
Biological Process (BP)negative regulation of cellular component organization0.1934.928e-08InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.54140.9043InformativeInherited
Biological Process (BP)cellular macromolecule catabolic process0.0036095.251e-09InformativeInherited
Biological Process (BP)cellular component morphogenesis0.89621InformativeInherited
Biological Process (BP)epithelium development0.011360.002343InformativeInherited
Biological Process (BP)embryo development ending in birth or egg hatching0.035250.01238InformativeInherited
Biological Process (BP)RNA catabolic process0.0005516.282e-10Highly InformativeDirect
Biological Process (BP)establishment or maintenance of cell polarity0.00040841.376e-09Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)peptidyl-lysine modification8.782e-120.0003918Highly InformativeDirect
Biological Process (BP)regulation of intracellular protein transport1.993e-069.003e-06Highly InformativeDirect
Biological Process (BP)protein localization to nucleus1.087e-070Highly InformativeDirect
Biological Process (BP)protein targeting to nucleus4.752e-100Highly InformativeDirect
Biological Process (BP)regulation of nucleocytoplasmic transport1.554e-077.581e-07Highly InformativeDirect
Biological Process (BP)eye morphogenesis0.00030491.069e-06Highly InformativeDirect
Biological Process (BP)nuclear import00Highly InformativeDirect
Biological Process (BP)epithelial tube formation2.048e-053.784e-11Highly InformativeDirect
Biological Process (BP)regulation of protein localization to nucleus2.39e-078.89e-05Highly InformativeDirect
Biological Process (BP)regulation of neural precursor cell proliferation0.00078978.36e-06Highly InformativeDirect
Biological Process (BP)positive regulation of apoptotic signaling pathway0.00047840.06434Highly InformativeInherited
Biological Process (BP)renal system development0.17150.3063Highly InformativeInherited
Biological Process (BP)protein dephosphorylation0.00012280.05658Highly InformativeInherited
Biological Process (BP)epithelial cell development0.056060.2342Highly InformativeInherited
Biological Process (BP)cell proliferation0.029570.6467Highly InformativeInherited
Biological Process (BP)hair follicle development0.052960.1211Highly InformativeInherited
Biological Process (BP)regulation of reproductive process0.022710.001234Highly InformativeInherited
Biological Process (BP)positive regulation of epithelial cell proliferation0.057430.164Highly InformativeInherited
Biological Process (BP)cell fate commitment0.075950.999Highly InformativeInherited
Biological Process (BP)lung development0.010910.6744Highly InformativeInherited
Biological Process (BP)mesenchyme development0.006411Highly InformativeInherited
Biological Process (BP)regulation of cellular response to growth factor stimulus0.0011430.6317Highly InformativeInherited
Biological Process (BP)regulation of epithelial cell differentiation0.0084190.01202Highly InformativeInherited
Biological Process (BP)tissue homeostasis0.07391Highly InformativeInherited
Biological Process (BP)limb morphogenesis0.010150.7524Highly InformativeInherited
Biological Process (BP)T cell differentiation0.032290.03671Highly InformativeInherited
Biological Process (BP)regulation of protein depolymerization0.006410Highly InformativeInherited
Biological Process (BP)telencephalon development0.093160.005097Highly InformativeInherited
Biological Process (BP)glial cell differentiation0.17280.06464Highly InformativeInherited
Biological Process (BP)negative regulation of cell differentiation0.88071Highly InformativeInherited
Biological Process (BP)pattern specification process0.25460.5334Highly InformativeInherited
Biological Process (BP)cellular modified amino acid biosynthetic process2.302e-100.001114Highly InformativeInherited
Biological Process (BP)regulation of microtubule polymerization or depolymerization0.47790.01568Highly InformativeInherited
Biological Process (BP)negative regulation of protein complex disassembly0.026040Highly InformativeInherited
Biological Process (BP)negative regulation of cytoskeleton organization0.17822.953e-06Highly InformativeInherited
Biological Process (BP)cell morphogenesis involved in differentiation0.49961Highly InformativeInherited
Biological Process (BP)regulation of organ morphogenesis0.013360.3497Highly InformativeInherited
Biological Process (BP)positive regulation of cell differentiation0.1370.2594Highly InformativeInherited
Biological Process (BP)morphogenesis of embryonic epithelium0.011950.0007343Highly InformativeInherited
Molecular Function (MF)binding3.815e-080Least InformativeDirect
Molecular Function (MF)enzyme regulator activity4.92e-060Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity11Moderately InformativeInherited
Molecular Function (MF)transporter activity0.85910.6513Moderately InformativeInherited
Molecular Function (MF)amide binding0.10150.8146InformativeInherited
Molecular Function (MF)protein transporter activity3.171e-090Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity2.411e-124.646e-07Highly InformativeDirect
Molecular Function (MF)monooxygenase activity1.043e-100.2225Highly InformativeInherited
Molecular Function (MF)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxyge2.841e-070.7471Highly InformativeInherited
Molecular Function (MF)peptide binding0.024260.2933Highly InformativeInherited
Cellular Component (CC)intracellular non-membrane-bounded organelle8.339e-054.143e-12Least InformativeDirect
Cellular Component (CC)membrane11Least InformativeInherited
Cellular Component (CC)cytoplasmic part11Least InformativeInherited
Cellular Component (CC)protein complex0.072.803e-10Least InformativeInherited
Cellular Component (CC)intracellular organelle part0.35970.0001905Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.61590.6664Least InformativeInherited
Cellular Component (CC)nuclear part4.992e-072.037e-10Moderately InformativeDirect
Cellular Component (CC)intrinsic to membrane0.66861Moderately InformativeInherited
Cellular Component (CC)plasma membrane part11Moderately InformativeInherited
Cellular Component (CC)cell projection0.021260.04848Moderately InformativeInherited
Cellular Component (CC)cytoskeleton10.01999Moderately InformativeInherited
Cellular Component (CC)endomembrane system0.26188.392e-14Moderately InformativeInherited
Cellular Component (CC)organelle envelope0.86070.898Moderately InformativeInherited
Cellular Component (CC)microtubule cytoskeleton4.364e-051.689e-14InformativeDirect
Cellular Component (CC)cell-cell junction0.31690.007945InformativeInherited
Cellular Component (CC)integral to membrane0.54491InformativeInherited
Cellular Component (CC)nuclear envelope0.0018744.8e-09InformativeInherited
Cellular Component (CC)trans-Golgi network8.808e-050Highly InformativeDirect
Cellular Component (CC)protein serine/threonine phosphatase complex00Highly InformativeDirect
Cellular Component (CC)lateral plasma membrane0.00038390.0003483Highly InformativeDirect
Cellular Component (CC)cell-cell contact zone0.00090383.404e-07Highly InformativeDirect
Cellular Component (CC)pore complex7.241e-050Highly InformativeDirect
Cellular Component (CC)spindle0.029338.058e-07Highly InformativeInherited
Cellular Component (CC)microvillus0.012770.4062Highly InformativeInherited
Cellular Component (CC)cell projection membrane0.0053181.02e-06Highly InformativeInherited
Cellular Component (CC)proteasome complex0.18250Highly InformativeInherited
Cellular Component (CC)adherens junction11Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)