SUPERFAMILY 1.75 HMM library and genome assignments server

Please note: Superfamily is currently under maintenance and some functionality may be limited. Please bear with us as we fix these problems.


Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (61) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 7,052 10,102 17
Proteins 6,938 9,662 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)developmental process0.020340.07608Least InformativeInherited
Biological Process (BP)multicellular organismal process0.048230.1689Least InformativeInherited
Biological Process (BP)single-organism cellular process0.060790.6823Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.018870.1331Least InformativeInherited
Biological Process (BP)response to stimulus0.013210.1077Least InformativeInherited
Biological Process (BP)localization0.014850.0002209Least InformativeInherited
Biological Process (BP)macromolecule localization0.000092530.000352Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.0031980.4424Moderately InformativeInherited
Biological Process (BP)response to organic substance0.12690.4271Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0019210.000006029Moderately InformativeInherited
Biological Process (BP)organic substance transport0.0020310.004051Moderately InformativeInherited
Biological Process (BP)lipid localization0.00016270.00000318InformativeDirect
Biological Process (BP)cellular component morphogenesis0.0049940.008716InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.0022630.04525InformativeInherited
Biological Process (BP)response to organic cyclic compound0.08970.04751InformativeInherited
Biological Process (BP)cellular component assembly involved in morphogenesis0.000018360.000008354Highly InformativeDirect
Biological Process (BP)external encapsulating structure organization0.0000014120.00000000001968Highly InformativeDirect
Cellular Component (CC)membrane0.058420.00000008882Least InformativeInherited
Cellular Component (CC)intrinsic to membrane0.00038490Moderately InformativeDirect
Cellular Component (CC)external encapsulating structure0.00019180.00005058InformativeDirect
Cellular Component (CC)cell junction0.00065270.006281InformativeInherited
Cellular Component (CC)anchored to membrane0.00000000009280Highly InformativeDirect
Cellular Component (CC)symplast0.000019070.000003765Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.0002209 Least Informative Direct
Biological Process (BP) biosynthetic process 0.2699 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.6823 Least Informative Inherited
Biological Process (BP) response to stimulus 0.1077 Least Informative Inherited
Biological Process (BP) developmental process 0.07608 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.1689 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.2579 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.5242 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.1331 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.000352 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 0.0004857 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.000006029 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.004689 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.1046 Moderately Informative Inherited
Biological Process (BP) ion transport 0.03863 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.4424 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.4271 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.01358 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.06704 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.004051 Moderately Informative Inherited
Biological Process (BP) anion transport 0.0007395 Informative Direct
Biological Process (BP) response to inorganic substance 0.00004606 Informative Direct
Biological Process (BP) lipid localization 0.00000318 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.0004138 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.000115 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.00007163 Informative Direct
Biological Process (BP) defense response 0.02177 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.006449 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.008716 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.04525 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.04751 Informative Inherited
Biological Process (BP) response to cold 0.0001232 Highly Informative Direct
Biological Process (BP) response to fungus 0.000003553 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 0.000008354 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 0.00000000001968 Highly Informative Direct
Biological Process (BP) inorganic anion transport 0.07145 Highly Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.004271 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.000003764 Informative Direct
Cellular Component (CC) membrane 0.00000008882 Least Informative Direct
Cellular Component (CC) intrinsic to membrane 0 Moderately Informative Direct
Cellular Component (CC) external encapsulating structure 0.00005058 Informative Direct
Cellular Component (CC) cell junction 0.006281 Informative Inherited
Cellular Component (CC) anchored to membrane 0 Highly Informative Direct
Cellular Component (CC) symplast 0.000003765 Highly Informative Direct

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure1Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)root system1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)leaf1Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon1Moderately InformativeInherited
Plant ANatomical entity (PAN)vascular system0.00006668InformativeDirect
Plant ANatomical entity (PAN)primordium0.0001938InformativeDirect
Plant ANatomical entity (PAN)root tip0.004428InformativeInherited
Plant ANatomical entity (PAN)lateral root primordium0.0000003704Highly InformativeDirect
Plant ANatomical entity (PAN)style0.000007464Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root0.00001763Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0001868Highly InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense0InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole0.0000000000001294InformativeDirect
Cellular componentGPI-anchor0.000002032InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Post-translational modificationProtease inhibitor0.000000000000001985InformativeDirect
Post-translational modificationAntimicrobial0.00000000000003394InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.0001713InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]