SUPERFAMILY 1.75 HMM library and genome assignments server


Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (43) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 4,782 7,834 17
Proteins 4,752 7,515 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)developmental process0.029190.2148Least InformativeInherited
Biological Process (BP)multicellular organismal process0.070450.3956Least InformativeInherited
Biological Process (BP)single-organism cellular process0.099710.888Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.031440.2322Least InformativeInherited
Biological Process (BP)response to stimulus0.025990.2861Least InformativeInherited
Biological Process (BP)localization0.0098090.0006915Least InformativeInherited
Biological Process (BP)macromolecule localization2.19e-050.0003775Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.0033760.3609Moderately InformativeInherited
Biological Process (BP)single-organism developmental process0.081260.6234Moderately InformativeInherited
Biological Process (BP)response to organic substance0.10620.3595Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0015226.239e-06Moderately InformativeInherited
Biological Process (BP)organic substance transport0.00078160.004779Moderately InformativeInherited
Biological Process (BP)lipid transport3.343e-081.655e-07InformativeDirect
Biological Process (BP)cellular component morphogenesis0.0053240.01423InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.0016350.0384InformativeInherited
Biological Process (BP)response to organic cyclic compound0.10620.04524InformativeInherited
Biological Process (BP)cellular component assembly involved in morphogenesis8.27e-065.784e-06Highly InformativeDirect
Biological Process (BP)external encapsulating structure organization2.019e-065.272e-11Highly InformativeDirect
Cellular Component (CC)membrane0.084015.769e-07Least InformativeInherited
Cellular Component (CC)intrinsic to membrane0.00077310Moderately InformativeDirect
Cellular Component (CC)external encapsulating structure0.00036850.001061InformativeInherited
Cellular Component (CC)cell wall0.00012030.0003756Highly InformativeDirect
Cellular Component (CC)anchored to membrane2.283e-100Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.0006915 Least Informative Direct
Biological Process (BP) biosynthetic process 0.3278 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.888 Least Informative Inherited
Biological Process (BP) response to stimulus 0.2861 Least Informative Inherited
Biological Process (BP) developmental process 0.2148 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.3956 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.2614 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.2322 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.0003775 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 6.239e-06 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.003092 Moderately Informative Inherited
Biological Process (BP) ion transport 0.02562 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.3609 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 0.6234 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.3595 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.04222 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.04754 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.004779 Moderately Informative Inherited
Biological Process (BP) lipid transport 1.655e-07 Informative Direct
Biological Process (BP) response to inorganic substance 6.3e-05 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 7.363e-05 Informative Direct
Biological Process (BP) defense response 0.02843 Informative Inherited
Biological Process (BP) anion transport 0.001002 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.007766 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.01423 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.0384 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.04524 Informative Inherited
Biological Process (BP) response to other organism 0.002236 Informative Inherited
Biological Process (BP) response to cold 0.0001429 Highly Informative Direct
Biological Process (BP) response to fungus 2.438e-05 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 5.784e-06 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 5.272e-11 Highly Informative Direct
Biological Process (BP) inorganic anion transport 0.08095 Highly Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.00827 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 1.332e-05 Informative Direct
Cellular Component (CC) membrane 5.769e-07 Least Informative Direct
Cellular Component (CC) intrinsic to membrane 0 Moderately Informative Direct
Cellular Component (CC) external encapsulating structure 0.001061 Informative Inherited
Cellular Component (CC) cell wall 0.0003756 Highly Informative Direct
Cellular Component (CC) anchored to membrane 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)root1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)vascular leaf1Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)androecium1Least InformativeInherited
Plant ANatomical entity (PAN)gynoecium1Least InformativeInherited
Plant ANatomical entity (PAN)stalk1Least InformativeInherited
Plant ANatomical entity (PAN)primordium0.0001989InformativeDirect
Plant ANatomical entity (PAN)root tip0.004455InformativeInherited
Plant ANatomical entity (PAN)lateral root primordium3.855e-07Highly InformativeDirect
Plant ANatomical entity (PAN)style7.597e-06Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root1.807e-05Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0001884Highly InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense2.278e-15InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole6.018e-14InformativeDirect
Cellular componentGPI-anchor1.902e-05InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Post-translational modificationProtease inhibitor4.42e-16InformativeDirect
Post-translational modificationAntimicrobial1.086e-14InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.000207InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]