SUPERFAMILY 1.75 HMM library and genome assignments server


Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (61) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 7,052 10,102 17
Proteins 6,938 9,662 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)developmental process0.019690.07047Least InformativeInherited
Biological Process (BP)multicellular organismal process0.047160.1574Least InformativeInherited
Biological Process (BP)single-organism cellular process0.056890.6446Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.017380.1198Least InformativeInherited
Biological Process (BP)response to stimulus0.011640.09304Least InformativeInherited
Biological Process (BP)localization0.014040.0001779Least InformativeInherited
Biological Process (BP)macromolecule localization9.39e-050.0003666Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.0031450.4429Moderately InformativeInherited
Biological Process (BP)response to organic substance0.12510.4178Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0018775.587e-06Moderately InformativeInherited
Biological Process (BP)organic substance transport0.00210.004327Moderately InformativeInherited
Biological Process (BP)lipid localization0.00016713.095e-06InformativeDirect
Biological Process (BP)cellular component morphogenesis0.0049390.008298InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.0021530.04407InformativeInherited
Biological Process (BP)response to organic cyclic compound0.09280.04876InformativeInherited
Biological Process (BP)cellular component assembly involved in morphogenesis1.575e-057.623e-06Highly InformativeDirect
Biological Process (BP)external encapsulating structure organization1.295e-061.595e-11Highly InformativeDirect
Cellular Component (CC)membrane0.054496.752e-08Least InformativeInherited
Cellular Component (CC)intrinsic to membrane0.00038740Moderately InformativeDirect
Cellular Component (CC)external encapsulating structure0.00017984.847e-05InformativeDirect
Cellular Component (CC)cell-cell junction0.00024120.001184InformativeInherited
Cellular Component (CC)anchored to membrane1.028e-100Highly InformativeDirect
Cellular Component (CC)symplast1.882e-053.629e-06Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.0001779 Least Informative Direct
Biological Process (BP) biosynthetic process 0.2467 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.6446 Least Informative Inherited
Biological Process (BP) response to stimulus 0.09304 Least Informative Inherited
Biological Process (BP) developmental process 0.07047 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.1574 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.2334 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.4919 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.1198 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.0003666 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 0.0003956 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 5.587e-06 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.004292 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.09849 Moderately Informative Inherited
Biological Process (BP) ion transport 0.03984 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.4429 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.4178 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.01093 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.06485 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.004327 Moderately Informative Inherited
Biological Process (BP) anion transport 0.0007043 Informative Direct
Biological Process (BP) response to inorganic substance 4.293e-05 Informative Direct
Biological Process (BP) lipid localization 3.095e-06 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.0003775 Informative Direct
Biological Process (BP) response to other organism 0.0003642 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 6.552e-05 Informative Direct
Biological Process (BP) defense response 0.02281 Informative Inherited
Biological Process (BP) nitrogen compound transport 0.006761 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.008298 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.04407 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.04876 Informative Inherited
Biological Process (BP) response to cold 0.000128 Highly Informative Direct
Biological Process (BP) response to fungus 4.106e-06 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 7.623e-06 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 1.595e-11 Highly Informative Direct
Biological Process (BP) inorganic anion transport 0.06949 Highly Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.003966 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 3.529e-06 Informative Direct
Cellular Component (CC) membrane 6.752e-08 Least Informative Direct
Cellular Component (CC) intrinsic to membrane 0 Moderately Informative Direct
Cellular Component (CC) external encapsulating structure 4.847e-05 Informative Direct
Cellular Component (CC) cell-cell junction 0.001184 Informative Inherited
Cellular Component (CC) anchored to membrane 0 Highly Informative Direct
Cellular Component (CC) symplast 3.629e-06 Highly Informative Direct

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure1Least InformativeInherited
Plant ANatomical entity (PAN)root system1Least InformativeInherited
Plant ANatomical entity (PAN)leaf1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon1Moderately InformativeInherited
Plant ANatomical entity (PAN)vascular system6.668e-05InformativeDirect
Plant ANatomical entity (PAN)primordium0.0001938InformativeDirect
Plant ANatomical entity (PAN)root tip0.004428InformativeInherited
Plant ANatomical entity (PAN)lateral root primordium3.704e-07Highly InformativeDirect
Plant ANatomical entity (PAN)style7.464e-06Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root1.763e-05Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0001868Highly InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense0InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole1.287e-13InformativeDirect
Cellular componentGPI-anchor2.022e-06InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Post-translational modificationProtease inhibitor1.981e-15InformativeDirect
Post-translational modificationAntimicrobial3.433e-14InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.0001737InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]