SUPERFAMILY 1.75 HMM library and genome assignments server

Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47698]
Superfamily:   Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [ 47699] (3)
Families:   Plant lipid-transfer and hydrophobic proteins [ 47700] (3)
  Proteinase/alpha-amylase inhibitors [ 47708] (3)
  Seed storage protein, 2S albumin [ 47715] (3)


Superfamily statistics
Genomes (61) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 7,052 10,102 17
Proteins 6,938 9,662 17


Functional annotation
General category Metabolism
Detailed category Lipid metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization0.017740.0003057Least InformativeInherited
Biological Process (BP)developmental process0.020460.07733Least InformativeInherited
Biological Process (BP)single-organism cellular process0.62441Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.0016680.01372Least InformativeInherited
Biological Process (BP)multicellular organismal process0.041740.1293Least InformativeInherited
Biological Process (BP)response to stimulus0.013080.11Least InformativeInherited
Biological Process (BP)macromolecule localization0.000071670.0002372Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.0031580.4419Moderately InformativeInherited
Biological Process (BP)response to organic substance0.1330.4345Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.0019590.000006436Moderately InformativeInherited
Biological Process (BP)organic substance transport0.0016320.003177Moderately InformativeInherited
Biological Process (BP)response to acid chemical0.0000010230.0000000000131InformativeDirect
Biological Process (BP)lipid localization0.00019830.000003897InformativeDirect
Biological Process (BP)single-organism membrane organization0.00043590.0003775InformativeDirect
Biological Process (BP)cellular component morphogenesis0.013740.01607InformativeInherited
Biological Process (BP)anatomical structure formation involved in morphogenesis0.0022330.04609InformativeInherited
Biological Process (BP)response to organic cyclic compound0.089010.04792InformativeInherited
Biological Process (BP)cellular component assembly involved in morphogenesis0.0000072970.00002102Highly InformativeDirect
Biological Process (BP)external encapsulating structure organization0.00000028580.00000000001973Highly InformativeDirect
Cellular Component (CC)membrane0.058350.00000008999Least InformativeInherited
Cellular Component (CC)intrinsic component of membrane0.0004650Moderately InformativeDirect
Cellular Component (CC)external encapsulating structure0.00019020.00005006InformativeDirect
Cellular Component (CC)cell junction0.0006390.006205InformativeInherited
Cellular Component (CC)anchored component of membrane0.000000000091390Highly InformativeDirect
Cellular Component (CC)symplast0.000018850.000003723Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.0003057 Least Informative Direct
Biological Process (BP) biosynthetic process 0.2695 Least Informative Inherited
Biological Process (BP) response to stimulus 0.11 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.6134 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.5707 Least Informative Inherited
Biological Process (BP) developmental process 0.07733 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.01372 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.1293 Least Informative Inherited
Biological Process (BP) macromolecule localization 0.0002372 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.0004451 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.000006436 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.006224 Moderately Informative Inherited
Biological Process (BP) defense response 0.01687 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.04609 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.3155 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.1066 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.4419 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.4345 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.01332 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.06774 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.003177 Moderately Informative Inherited
Biological Process (BP) ion transport 0.1212 Moderately Informative Inherited
Biological Process (BP) response to acid chemical 0.0000000000131 Informative Direct
Biological Process (BP) anion transport 0.0004228 Informative Direct
Biological Process (BP) response to inorganic substance 0.00004697 Informative Direct
Biological Process (BP) lipid localization 0.000003897 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.0004325 Informative Direct
Biological Process (BP) single-organism membrane organization 0.0003775 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.0001157 Informative Direct
Biological Process (BP) defense response to other organism 0.0002522 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.0001002 Informative Direct
Biological Process (BP) nitrogen compound transport 0.005605 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.01607 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.04609 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.04792 Informative Inherited
Biological Process (BP) response to cold 0.0001327 Highly Informative Direct
Biological Process (BP) response to fungus 0.000003441 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 0.00002102 Highly Informative Direct
Biological Process (BP) external encapsulating structure organization 0.00000000001973 Highly Informative Direct
Biological Process (BP) inorganic anion transport 0.1072 Highly Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.001551 Moderately Informative Inherited
Molecular Function (MF) enzyme inhibitor activity 0.000003846 Informative Direct
Cellular Component (CC) membrane 0.00000008999 Least Informative Direct
Cellular Component (CC) intrinsic component of membrane 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane part 0.4064 Moderately Informative Inherited
Cellular Component (CC) external encapsulating structure 0.00005006 Informative Direct
Cellular Component (CC) intrinsic component of plasma membrane 1 Informative Inherited
Cellular Component (CC) cell junction 0.006205 Informative Inherited
Cellular Component (CC) anchored component of membrane 0 Highly Informative Direct
Cellular Component (CC) symplast 0.000003723 Highly Informative Direct

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant1Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue1Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)flower1Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure1Least InformativeInherited
Plant ANatomical entity (PAN)root system1Least InformativeInherited
Plant ANatomical entity (PAN)leaf1Least InformativeInherited
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure1Least InformativeInherited
Plant ANatomical entity (PAN)cotyledon1Moderately InformativeInherited
Plant ANatomical entity (PAN)vascular system0.00006668InformativeDirect
Plant ANatomical entity (PAN)primordium0.0001938InformativeDirect
Plant ANatomical entity (PAN)root tip0.004428InformativeInherited
Plant ANatomical entity (PAN)lateral root primordium0.0000003704Highly InformativeDirect
Plant ANatomical entity (PAN)style0.000007464Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root0.00001763Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0001868Highly InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processPlant defense0InformativeDirect
Cellular componentMembrane1Least InformativeInherited
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentVacuole0.0000000000001294InformativeDirect
Cellular componentGPI-anchor0.000002032InformativeDirect
DiseaseAllergen0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Post-translational modificationProtease inhibitor0.000000000000001985InformativeDirect
Post-translational modificationAntimicrobial0.00000000000003394InformativeDirect
Post-translational modificationStorage protein0Highly InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationPyrrolidone carboxylic acid0.0001713InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 13 hidden Markov models representing the Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]