|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
regulation of DNA recombination |
4.094e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
response to protozoan |
4.357e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
morphogenesis of a branching structure |
0.0002512 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
neutrophil homeostasis |
1.206e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
neutrophil apoptotic process |
2.431e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cytokine production |
9.426e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
placenta development |
0.0007149 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein phosphorylation |
2.44e-12 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell-matrix adhesion |
9.207e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cytokine-mediated signaling pathway |
7.797e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to molecule of bacterial origin |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cell activation involved in immune response |
0.0006544 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
T cell activation involved in immune response |
0.0001173 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
T cell differentiation involved in immune response |
3.284e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
alpha-beta T cell differentiation involved in immune response |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
immune system development |
2.912e-13 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte differentiation |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of immune system process |
0 |
1.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte activation |
0 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of leukocyte activation |
3.579e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte activation |
8.878e-08 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of production of molecular mediator of immune response |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell mediated immunity |
1.757e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cytokine production involved in immune response |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cytokine secretion involved in immune response |
3.682e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of myeloid leukocyte differentiation |
0.0001241 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
peptide secretion |
2.273e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of adaptive immune response |
4.939e-07 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of immunoglobulin mediated immune response |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell apoptotic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein import into nucleus |
6.846e-07 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
inflammatory cell apoptotic process |
4.851e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to stress |
1.479e-05 |
0.8125 |
-- |
DIRECT |
| Biological Process (BP) |
cell communication |
5.74e-08 |
0.8477 |
-- |
DIRECT |
| Biological Process (BP) |
intracellular protein kinase cascade |
3.022e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
JAK-STAT cascade |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
female pregnancy |
3.721e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
embryo implantation |
9.695e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
blood coagulation |
0.0001071 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
biological_process |
6.402e-11 |
0 |
-- |
DIRECT |
| Biological Process (BP) |
cholesterol metabolic process |
5.932e-05 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
cell death |
7.041e-08 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell proliferation |
0 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
adult feeding behavior |
4.294e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to biotic stimulus |
0 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biosynthetic process |
2.965e-06 |
1.495 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catabolic process |
0.0001154 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of catabolic process |
0 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell communication |
1.096e-07 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of intracellular protein kinase cascade |
1.366e-09 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glucose metabolic process |
1.137e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell death |
3.527e-13 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
programmed cell death |
6.626e-11 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
peptide transport |
0.0006998 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
death |
4.774e-08 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
peptidyl-tyrosine modification |
2.126e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphate metabolic process |
0 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
gland morphogenesis |
0.000363 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
signaling |
3.005e-10 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of signaling |
8.576e-09 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
peptide hormone secretion |
1.642e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
hemopoiesis |
0 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
myeloid cell differentiation |
0.0009016 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
natural killer cell activation |
0.0001221 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell migration |
6.494e-08 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
neutrophil chemotaxis |
6.485e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
mammary gland development |
4.937e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
endoplasmic reticulum unfolded protein response |
0.0004071 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0 |
1.208 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of defense response |
1.049e-07 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein modification process |
1.45e-13 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of myelination |
0.0001823 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of myelination |
2.593e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to nutrient levels |
5.184e-06 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to food |
1.716e-14 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of response to food |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of appetite |
8.675e-13 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of appetite |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of response to nutrient levels |
1.53e-12 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
0 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
1.162e-11 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-1 beta production |
8.002e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-6 production |
3.937e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of interleukin-6 production |
1.598e-13 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of interleukin-1 beta production |
2.266e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
receptor biosynthetic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of homeostatic process |
1.332e-06 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
myeloid cell apoptotic process |
2.258e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of myeloid cell apoptotic process |
4.642e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of myeloid cell apoptotic process |
6.407e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to type I interferon |
4.401e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to unfolded protein |
0.0004795 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
response to decreased oxygen levels |
9.783e-06 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of meiosis |
7.481e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cytokine biosynthetic process |
3.102e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
type 2 immune response |
5.762e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of T cell proliferation |
1.373e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein catabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphorylation |
0 |
1.469 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphorylation |
6.243e-09 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of tyrosine phosphorylation of STAT protein |
1.179e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of tyrosine phosphorylation of STAT protein |
1.321e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
defense response to protozoan |
5.582e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
receptor metabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of CD4-positive, alpha-beta T cell differentiation |
3.682e-14 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of multi-organism process |
9.724e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of symbiosis, encompassing mutualism through parasitism |
1.937e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of molecular function |
2.874e-07 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of growth of symbiont in host |
4.984e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of growth of symbiont in host |
5.889e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
modulation of growth of symbiont involved in interaction with host |
5.51e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of growth of symbiont involved in interaction with host |
4.401e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
single organism signaling |
3.948e-09 |
0.8601 |
-- |
DIRECT |
| Biological Process (BP) |
single-multicellular organism process |
1.083e-11 |
0.6383 |
-- |
DIRECT |
| Biological Process (BP) |
T cell selection |
0.0006378 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of isotype switching |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte activation |
2.209e-06 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of MHC class II biosynthetic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of MHC class II biosynthetic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nitric oxide biosynthetic process |
0.000128 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell differentiation |
0 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of T-helper cell differentiation |
0.0001156 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of myeloid cell differentiation |
4.769e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of glial cell differentiation |
6.723e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of glial cell differentiation |
3.435e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of isotype switching |
8.003e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of meiosis |
7.749e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of proteolysis |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription, DNA-dependent |
2.364e-12 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of DNA recombination |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nucleobase-containing compound metabolic process |
4.923e-07 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphate metabolic process |
4.032e-14 |
1.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of T cell homeostatic proliferation |
2.053e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of JAK-STAT cascade |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of JAK-STAT cascade |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of Ras protein signal transduction |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
alpha-beta T cell activation |
5.192e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
hormone secretion |
1.199e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of hormone secretion |
0.00036 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biological process |
0 |
0.8182 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of biological process |
1.449e-06 |
0.8665 |
-- |
DIRECT |
| Biological Process (BP) |
response to steroid hormone stimulus |
4.108e-10 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of response to stimulus |
3.227e-06 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of astrocyte differentiation |
1.1e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of astrocyte differentiation |
2.699e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
5.235e-07 |
0.8069 |
-- |
DIRECT |
| Biological Process (BP) |
cellular developmental process |
0.0003477 |
0.9666 |
-- |
DIRECT |
| Biological Process (BP) |
homeostasis of number of cells |
8.502e-14 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte proliferation |
2.432e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of lymphocyte proliferation |
0.0004824 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of defense response to virus by host |
2.442e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of interleukin-1 beta secretion |
1.446e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cytokine secretion |
8.82e-07 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein secretion |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cytokine secretion |
1.794e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein secretion |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of peptidyl-tyrosine phosphorylation |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
9.561e-07 |
0.4486 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of B cell activation |
4.008e-15 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell activation |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell activation |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of B cell activation |
0.0007608 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of membrane protein ectodomain proteolysis |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of membrane protein ectodomain proteolysis |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of transport |
4.008e-15 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of DNA metabolic process |
1.53e-14 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of small GTPase mediated signal transduction |
2.971e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of sequence-specific DNA binding transcription factor activity |
6.045e-12 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
nuclear transport |
0.0001333 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphorus metabolic process |
3.329e-14 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein transport |
2.114e-11 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of lymphocyte activation |
0.0002106 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of RNA metabolic process |
9.892e-05 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transferase activity |
3.217e-05 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transferase activity |
4.117e-05 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
response to glucocorticoid stimulus |
0 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of meiotic cell cycle |
1.949e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
defense response to virus |
2.725e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
maternal process involved in female pregnancy |
0.0001119 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
4.36e-05 |
0.7959 |
-- |
DIRECT |
| Biological Process (BP) |
type I interferon-mediated signaling pathway |
0.0001148 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of type I interferon-mediated signaling pathway |
2.442e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular localization |
0 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
branching involved in mammary gland duct morphogenesis |
3.506e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
mammary gland duct morphogenesis |
4.969e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
adipose tissue development |
1.452e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of response to cytokine stimulus |
8.584e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
0 |
0.4202 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of establishment of protein localization |
0.0002649 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
response to oxygen levels |
1.863e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte proliferation |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of leukocyte proliferation |
8.855e-13 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to interleukin-18 |
2.912e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to lipopolysaccharide |
0.0004343 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to cytokine stimulus |
3.405e-11 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to interleukin-18 |
1.153e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to type I interferon |
8.357e-06 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
leukocyte apoptotic process |
1.925e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of primary metabolic process |
3.487e-05 |
0.7852 |
-- |
DIRECT |
| Biological Process (BP) |
cell-type specific apoptotic process |
1.534e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
response to peptide |
0.0003678 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte differentiation |
1.286e-13 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte apoptotic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte apoptotic process |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of CD4-positive, alpha-beta T cell activation |
0.0007363 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of T cell activation |
1 |
2.097 |
-- |
INHERITED FROM: regulation of T-helper 17 cell differentiation || regulation of CD4-positive, alpha-beta T cell activation || regulation of T-helper cell differentiation || regulation of T cell homeostatic proliferation || positive regulation of T cell proliferation || regulation of CD4-positive, alpha-beta T cell differentiation |
| Biological Process (BP) |
regulation of alpha-beta T cell activation |
0.7525 |
2.222 |
-- |
INHERITED FROM: regulation of T-helper 17 cell differentiation || regulation of CD4-positive, alpha-beta T cell activation || regulation of T-helper cell differentiation || regulation of CD4-positive, alpha-beta T cell differentiation |
| Biological Process (BP) |
regulation of T cell differentiation |
0.2819 |
2.222 |
-- |
INHERITED FROM: regulation of T-helper 17 cell differentiation || regulation of T-helper cell differentiation || regulation of CD4-positive, alpha-beta T cell differentiation |
| Biological Process (BP) |
regulation of alpha-beta T cell differentiation |
0.4124 |
2.222 |
-- |
INHERITED FROM: regulation of T-helper 17 cell differentiation || regulation of T-helper cell differentiation || regulation of CD4-positive, alpha-beta T cell differentiation |
| Biological Process (BP) |
regulation of lymphocyte differentiation |
0.8959 |
2.222 |
-- |
INHERITED FROM: regulation of T-helper 17 cell differentiation || regulation of T-helper cell differentiation || positive regulation of natural killer cell differentiation || regulation of CD4-positive, alpha-beta T cell differentiation |
| Biological Process (BP) |
regulation of programmed cell death |
0.4008 |
1.319 |
-- |
INHERITED FROM: regulation of leukocyte apoptotic process || regulation of myeloid cell apoptotic process || negative regulation of mast cell apoptotic process || negative regulation of myeloid cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of B cell apoptotic process || regulation of mast cell apoptotic process || regulation of B cell apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
response to nitrogen compound |
0.3039 |
1.377 |
-- |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide || response to growth hormone stimulus |
| Biological Process (BP) |
cellular response to hormone stimulus |
1 |
1.585 |
-- |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway |
| Biological Process (BP) |
cellular response to organic nitrogen |
0.9359 |
1.699 |
-- |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway |
| Biological Process (BP) |
cellular response to molecule of bacterial origin |
0.9326 |
2.222 |
-- |
INHERITED FROM: cellular response to lipopolysaccharide |
| Biological Process (BP) |
cellular response to lipid |
0.5337 |
1.745 |
-- |
INHERITED FROM: cellular response to lipopolysaccharide |
| Biological Process (BP) |
regulation of lymphocyte apoptotic process |
0.01336 |
2.699 |
-- |
INHERITED FROM: positive regulation of lymphocyte apoptotic process || regulation of B cell apoptotic process || positive regulation of B cell apoptotic process |
| Biological Process (BP) |
single-organism process |
0.0177 |
0.3316 |
-- |
INHERITED FROM: morphogenesis of a branching epithelium || natural killer cell activation || cell activation || mammary gland duct morphogenesis || adult feeding behavior || mammary gland fat development || cell activation involved in immune response || neutrophil chemotaxis || hemostasis || leukocyte proliferation || alpha-beta T cell activation || T cell selection || cellular response to interleukin-18 || alpha-beta T cell differentiation involved in immune response || single-multicellular organism process || CD8-positive, alpha-beta T cell differentiation involved in immune response || hematopoietic or lymphoid organ development || organ development || nucleocytoplasmic transport || cellular response to lipopolysaccharide || cell communication || type I interferon-mediated signaling pathway || system development || protein import into nucleus || protein import || peptide hormone secretion || placenta development || intracellular protein kinase cascade || amide transport || regulation of body fluid levels || adipose tissue development || mammary gland development || neutrophil apoptotic process || osteoclast proliferation || nuclear import || positive regulation of astrocyte differentiation || single-organism developmental process || endoplasmic reticulum unfolded protein response || immune system development || maternal process involved in female pregnancy || gland morphogenesis || cell death || branching involved in mammary gland duct morphogenesis || peptide secretion || cellular response to type I interferon || death || coagulation || inflammatory cell apoptotic process || blood coagulation || cellular response to cytokine stimulus || protein targeting to nucleus || regulation of astrocyte differentiation || cytokine-mediated signaling pathway || T cell differentiation involved in immune response || embryonic placenta development || protein localization to nucleus || nuclear transport || STAT protein import into nucleus || cellular response to growth hormone stimulus || leukocyte differentiation || single organism signaling || myeloid cell apoptotic process || regulation of glial cell differentiation || cell-type specific apoptotic process || positive regulation of glial cell differentiation || cellular response to unfolded protein || embryo implantation || cellular developmental process || hormone transport || mammary gland epithelium development || JAK-STAT cascade || leukocyte apoptotic process || mammary duct terminal end bud growth || cell proliferation || gland development || hormone secretion || tyrosine phosphorylation of Stat3 protein || peptide transport || leukocyte activation || cell differentiation || growth hormone receptor signaling pathway || myeloid cell differentiation || morphogenesis of a branching structure || T cell activation involved in immune response || hemopoiesis || programmed cell death |
| Biological Process (BP) |
tube morphogenesis |
0.4936 |
1.854 |
-- |
INHERITED FROM: mammary duct terminal end bud growth || mammary gland duct morphogenesis || branching involved in mammary gland duct morphogenesis |
| Biological Process (BP) |
mammary gland morphogenesis |
0.09817 |
2.699 |
-- |
INHERITED FROM: mammary duct terminal end bud growth || branching involved in mammary gland duct morphogenesis || mammary gland duct morphogenesis |
| Biological Process (BP) |
developmental growth involved in morphogenesis |
0.001973 |
2.097 |
-- |
INHERITED FROM: mammary duct terminal end bud growth |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.002087 |
1.658 |
-- |
INHERITED FROM: mammary gland duct morphogenesis || morphogenesis of a branching epithelium || mammary duct terminal end bud growth || branching involved in mammary gland duct morphogenesis |
| Biological Process (BP) |
branching morphogenesis of an epithelial tube |
0.3093 |
2.097 |
-- |
INHERITED FROM: branching involved in mammary gland duct morphogenesis |
| Biological Process (BP) |
cellular response to peptide |
0.3384 |
1.921 |
-- |
INHERITED FROM: growth hormone receptor signaling pathway || cellular response to growth hormone stimulus |
| Biological Process (BP) |
response to peptide hormone stimulus |
0.3942 |
1.921 |
-- |
INHERITED FROM: growth hormone receptor signaling pathway || response to growth hormone stimulus || cellular response to growth hormone stimulus |
| Biological Process (BP) |
multicellular organism reproduction |
1 |
1.301 |
-- |
INHERITED FROM: maternal process involved in female pregnancy |
| Biological Process (BP) |
response to chemical stimulus |
0.04741 |
0.8861 |
-- |
INHERITED FROM: response to glucocorticoid stimulus || cytokine-mediated signaling pathway || cellular response to unfolded protein || response to interleukin-18 || cellular response to type I interferon || cellular response to lipopolysaccharide || cellular response to growth hormone stimulus || response to lipopolysaccharide || growth hormone receptor signaling pathway || response to peptide || response to growth hormone stimulus || response to type I interferon || type I interferon-mediated signaling pathway || response to organic substance || response to lipid || cellular response to interleukin-18 || response to corticosteroid stimulus || response to molecule of bacterial origin || cellular response to cytokine stimulus || neutrophil chemotaxis || response to steroid hormone stimulus || endoplasmic reticulum unfolded protein response || response to cytokine stimulus |
| Biological Process (BP) |
regulation of catalytic activity |
1 |
1.155 |
-- |
INHERITED FROM: positive regulation of transferase activity || regulation of transferase activity |
| Biological Process (BP) |
regulation of RNA metabolic process |
1 |
1.131 |
-- |
INHERITED FROM: positive regulation of RNA metabolic process || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of transport |
0.0354 |
1.155 |
-- |
INHERITED FROM: regulation of protein transport || negative regulation of transport || negative regulation of protein transport || regulation of interleukin-1 beta secretion || regulation of cytokine secretion || positive regulation of transport || regulation of cytokine secretion involved in immune response || positive regulation of interleukin-1 beta secretion || regulation of protein secretion || positive regulation of protein transport || negative regulation of hormone secretion || negative regulation of cytokine secretion involved in immune response || negative regulation of protein secretion || negative regulation of cytokine secretion || negative regulation of secretion || positive regulation of immunoglobulin secretion || positive regulation of secretion || regulation of secretion || positive regulation of protein secretion |
| Biological Process (BP) |
intracellular transport |
0.5383 |
1.194 |
-- |
INHERITED FROM: nuclear import || nuclear transport || protein targeting to nucleus || STAT protein import into nucleus || nucleocytoplasmic transport || protein import into nucleus |
| Biological Process (BP) |
establishment of localization in cell |
0.2338 |
1.119 |
-- |
INHERITED FROM: nuclear import || nucleocytoplasmic transport || peptide hormone secretion || nuclear transport || protein targeting to nucleus || STAT protein import into nucleus || protein import into nucleus || hormone secretion |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0.008879 |
1.237 |
-- |
INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
1 |
1.119 |
-- |
INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
0.4731 |
1.167 |
-- |
INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
1 |
1.009 |
-- |
INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || negative regulation of cytokine biosynthetic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || positive regulation of interleukin-6 biosynthetic process || regulation of cytokine biosynthetic process || positive regulation of cellular biosynthetic process || regulation of nitric oxide biosynthetic process || regulation of chemokine biosynthetic process || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
negative regulation of cellular protein metabolic process |
0.008262 |
1.62 |
-- |
INHERITED FROM: negative regulation of membrane protein ectodomain proteolysis || negative regulation of proteolysis |
| Biological Process (BP) |
regulation of immunoglobulin production |
0.05669 |
2.699 |
-- |
INHERITED FROM: positive regulation of immunoglobulin secretion || positive regulation of isotype switching || regulation of isotype switching |
| Biological Process (BP) |
regulation of biological quality |
0.672 |
0.8539 |
-- |
INHERITED FROM: regulation of body fluid levels || regulation of appetite || hormone transport || neutrophil apoptotic process || negative regulation of appetite || homeostasis of number of cells || blood coagulation || peptide hormone secretion || neutrophil homeostasis || hemostasis || hormone secretion |
| Biological Process (BP) |
positive regulation of lymphocyte activation |
0.9099 |
2.222 |
-- |
INHERITED FROM: positive regulation of B cell activation || positive regulation of T cell proliferation || positive regulation of natural killer cell differentiation || positive regulation of isotype switching |
| Biological Process (BP) |
regulation of steroid metabolic process |
0.001574 |
2 |
-- |
INHERITED FROM: regulation of steroid biosynthetic process |
| Biological Process (BP) |
regulation of lipid biosynthetic process |
0.05078 |
1.854 |
-- |
INHERITED FROM: regulation of steroid biosynthetic process |
| Biological Process (BP) |
positive regulation of cytokine secretion |
0.004274 |
2.699 |
-- |
INHERITED FROM: positive regulation of interleukin-1 beta secretion |
| Biological Process (BP) |
positive regulation of interleukin-1 secretion |
0.9045 |
2.699 |
-- |
INHERITED FROM: positive regulation of interleukin-1 beta secretion |
| Biological Process (BP) |
regulation of interleukin-1 secretion |
0.8007 |
2.398 |
-- |
INHERITED FROM: regulation of interleukin-1 beta secretion || positive regulation of interleukin-1 beta secretion |
| Biological Process (BP) |
regulation of response to biotic stimulus |
0.3627 |
2.699 |
-- |
INHERITED FROM: regulation of defense response to virus by host |
| Biological Process (BP) |
regulation of defense response to virus |
0.201 |
2.699 |
-- |
INHERITED FROM: regulation of defense response to virus by host |
| Biological Process (BP) |
positive regulation of cell development |
0.5315 |
2.222 |
-- |
INHERITED FROM: positive regulation of astrocyte differentiation || positive regulation of glial cell differentiation |
| Biological Process (BP) |
positive regulation of gliogenesis |
0.005727 |
2.699 |
-- |
INHERITED FROM: positive regulation of astrocyte differentiation || positive regulation of glial cell differentiation |
| Biological Process (BP) |
positive regulation of neurogenesis |
0.00181 |
2.222 |
-- |
INHERITED FROM: positive regulation of astrocyte differentiation || positive regulation of glial cell differentiation |
| Biological Process (BP) |
regulation of gliogenesis |
0.02184 |
2.398 |
-- |
INHERITED FROM: positive regulation of astrocyte differentiation || regulation of glial cell differentiation || positive regulation of glial cell differentiation || regulation of astrocyte differentiation |
| Biological Process (BP) |
neurogenesis |
1 |
1.357 |
-- |
INHERITED FROM: regulation of astrocyte differentiation || regulation of glial cell differentiation || positive regulation of astrocyte differentiation || positive regulation of glial cell differentiation |
| Biological Process (BP) |
regulation of neurogenesis |
0.9398 |
1.699 |
-- |
INHERITED FROM: regulation of astrocyte differentiation || regulation of glial cell differentiation || positive regulation of astrocyte differentiation || positive regulation of glial cell differentiation |
| Biological Process (BP) |
regulation of multicellular organismal development |
0.00179 |
1.268 |
-- |
INHERITED FROM: regulation of astrocyte differentiation || positive regulation of odontogenesis || regulation of myelination || positive regulation of myeloid leukocyte differentiation || regulation of odontogenesis of dentin-containing tooth || negative regulation of myelination || positive regulation of myeloid cell differentiation || regulation of odontogenesis || positive regulation of natural killer cell differentiation || positive regulation of odontogenesis of dentin-containing tooth || positive regulation of isotype switching || regulation of myeloid cell differentiation || regulation of glial cell differentiation || regulation of T-helper 17 cell differentiation || positive regulation of astrocyte differentiation || positive regulation of leukocyte differentiation || regulation of CD4-positive, alpha-beta T cell differentiation || positive regulation of glial cell differentiation || positive regulation of monocyte differentiation || regulation of leukocyte differentiation || regulation of isotype switching || regulation of T-helper cell differentiation |
| Biological Process (BP) |
anatomical structure development |
0.01655 |
0.7212 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || organ development || morphogenesis of a branching epithelium || gland morphogenesis || branching involved in mammary gland duct morphogenesis || mammary gland epithelium development || system development || mammary gland duct morphogenesis || mammary gland fat development || placenta development || mammary duct terminal end bud growth || gland development || regulation of astrocyte differentiation || adipose tissue development || T cell differentiation involved in immune response || mammary gland development || embryonic placenta development || leukocyte differentiation || myeloid cell differentiation || morphogenesis of a branching structure || T cell selection || regulation of glial cell differentiation || connective tissue development || positive regulation of astrocyte differentiation || alpha-beta T cell differentiation involved in immune response || hemopoiesis || CD8-positive, alpha-beta T cell differentiation involved in immune response || positive regulation of glial cell differentiation || immune system development |
| Biological Process (BP) |
multicellular organismal development |
0.2305 |
0.7496 |
-- |
INHERITED FROM: hematopoietic or lymphoid organ development || organ development || embryo implantation || gland morphogenesis || branching involved in mammary gland duct morphogenesis || mammary gland epithelium development || system development || mammary gland duct morphogenesis || mammary gland fat development || placenta development || mammary duct terminal end bud growth || gland development || regulation of astrocyte differentiation || adipose tissue development || T cell differentiation involved in immune response || mammary gland development || embryonic placenta development || leukocyte differentiation || myeloid cell differentiation || T cell selection || regulation of glial cell differentiation || positive regulation of astrocyte differentiation || alpha-beta T cell differentiation involved in immune response || hemopoiesis || CD8-positive, alpha-beta T cell differentiation involved in immune response || positive regulation of glial cell differentiation || immune system development |
| Biological Process (BP) |
regulation of hormone secretion |
0.002796 |
2.222 |
-- |
INHERITED FROM: negative regulation of hormone secretion |
| Biological Process (BP) |
regulation of small GTPase mediated signal transduction |
0.6738 |
2 |
-- |
INHERITED FROM: positive regulation of Ras protein signal transduction || positive regulation of small GTPase mediated signal transduction || regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of T cell proliferation |
0.23 |
2.398 |
-- |
INHERITED FROM: regulation of T cell homeostatic proliferation || positive regulation of T cell proliferation |
| Biological Process (BP) |
regulation of cell cycle |
1 |
1.444 |
-- |
INHERITED FROM: negative regulation of meiosis || regulation of meiotic cell cycle || regulation of meiosis |
| Biological Process (BP) |
negative regulation of cell cycle process |
1 |
1.796 |
-- |
INHERITED FROM: negative regulation of meiosis |
| Biological Process (BP) |
regulation of myeloid leukocyte differentiation |
0.002425 |
2.699 |
-- |
INHERITED FROM: positive regulation of monocyte differentiation || positive regulation of myeloid leukocyte differentiation |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
1 |
1.066 |
-- |
INHERITED FROM: positive regulation of interleukin-6 biosynthetic process || regulation of MHC class II biosynthetic process || regulation of sequence-specific DNA binding transcription factor activity || regulation of cytokine biosynthetic process || negative regulation of cytokine biosynthetic process || positive regulation of macromolecule biosynthetic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of MHC class II biosynthetic process || regulation of chemokine biosynthetic process || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
positive regulation of cytokine biosynthetic process |
0.001495 |
2.398 |
-- |
INHERITED FROM: positive regulation of interleukin-6 biosynthetic process |
| Biological Process (BP) |
regulation of chemokine production |
0.2506 |
2.699 |
-- |
INHERITED FROM: regulation of chemokine biosynthetic process |
| Biological Process (BP) |
protein localization |
0.4566 |
1.222 |
-- |
INHERITED FROM: protein targeting to nucleus || STAT protein import into nucleus || protein localization to nucleus || protein import into nucleus || protein import |
| Biological Process (BP) |
cellular protein localization |
0.1488 |
1.337 |
-- |
INHERITED FROM: protein targeting to nucleus || STAT protein import into nucleus || protein localization to nucleus || protein import into nucleus |
| Biological Process (BP) |
cellular macromolecule localization |
0.184 |
1.319 |
-- |
INHERITED FROM: protein targeting to nucleus || STAT protein import into nucleus || protein localization to nucleus || protein import into nucleus |
| Biological Process (BP) |
negative regulation of growth |
0.5892 |
1.854 |
-- |
INHERITED FROM: negative regulation of growth of symbiont involved in interaction with host || negative regulation of growth of symbiont in host |
| Biological Process (BP) |
regulation of cell motility |
0.1192 |
1.745 |
-- |
INHERITED FROM: regulation of blood vessel endothelial cell migration || regulation of cell migration || regulation of endothelial cell migration |
| Biological Process (BP) |
cellular response to stimulus |
0.2606 |
0.7645 |
-- |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || cytokine-mediated signaling pathway || cellular response to unfolded protein || cellular response to type I interferon || cellular response to lipopolysaccharide || STAT protein import into nucleus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || type I interferon-mediated signaling pathway || JAK-STAT cascade || cellular response to interleukin-18 || cellular response to cytokine stimulus || intracellular protein kinase cascade || neutrophil chemotaxis || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
protein modification process |
1 |
0.9066 |
-- |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine modification || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
macromolecule modification |
1 |
0.8416 |
-- |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine modification || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
cellular protein metabolic process |
1 |
0.6778 |
-- |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine modification || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
phosphorus metabolic process |
1 |
0.8013 |
-- |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
phosphorylation |
0.791 |
1.398 |
-- |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
1 |
1.301 |
-- |
INHERITED FROM: negative regulation of protein catabolic process || negative regulation of membrane protein ectodomain proteolysis || negative regulation of proteolysis || negative regulation of cytokine biosynthetic process |
| Biological Process (BP) |
positive regulation of mononuclear cell proliferation |
1 |
2.398 |
-- |
INHERITED FROM: positive regulation of T cell proliferation |
| Biological Process (BP) |
positive regulation of lymphocyte proliferation |
0.02751 |
2.398 |
-- |
INHERITED FROM: positive regulation of T cell proliferation |
| Biological Process (BP) |
positive regulation of T cell activation |
0.01112 |
2.398 |
-- |
INHERITED FROM: positive regulation of T cell proliferation |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
1 |
1.854 |
-- |
INHERITED FROM: negative regulation of cytokine biosynthetic process |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
1 |
1.658 |
-- |
INHERITED FROM: negative regulation of cytokine biosynthetic process |
| Biological Process (BP) |
response to unfolded protein |
0.001136 |
2.398 |
-- |
INHERITED FROM: cellular response to unfolded protein || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
cellular response to topologically incorrect protein |
0.02095 |
2.222 |
-- |
INHERITED FROM: cellular response to unfolded protein || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
negative regulation of programmed cell death |
0.9883 |
1.796 |
-- |
INHERITED FROM: negative regulation of myeloid cell apoptotic process || negative regulation of mast cell apoptotic process |
| Biological Process (BP) |
macromolecule biosynthetic process |
0.002056 |
0.8861 |
-- |
INHERITED FROM: receptor biosynthetic process |
| Biological Process (BP) |
organic substance biosynthetic process |
0.7154 |
0.5376 |
-- |
INHERITED FROM: receptor biosynthetic process |
| Biological Process (BP) |
positive regulation of interleukin-1 production |
0.1391 |
2.398 |
-- |
INHERITED FROM: positive regulation of interleukin-1 beta production || positive regulation of interleukin-1 beta secretion |
| Biological Process (BP) |
regulation of response to extracellular stimulus |
0.03306 |
2.222 |
-- |
INHERITED FROM: negative regulation of appetite || regulation of response to food || negative regulation of response to food || negative regulation of response to nutrient levels |
| Biological Process (BP) |
response to extracellular stimulus |
0.005479 |
1.699 |
-- |
INHERITED FROM: regulation of appetite || negative regulation of appetite || response to nutrient levels |
| Biological Process (BP) |
negative regulation of response to extracellular stimulus |
0.001367 |
2.398 |
-- |
INHERITED FROM: negative regulation of response to food || negative regulation of appetite || negative regulation of response to nutrient levels |
| Biological Process (BP) |
negative regulation of neurological system process |
0.1129 |
2.398 |
-- |
INHERITED FROM: negative regulation of myelination |
| Biological Process (BP) |
regulation of transmission of nerve impulse |
1 |
2.097 |
-- |
INHERITED FROM: regulation of myelination || negative regulation of myelination |
| Biological Process (BP) |
negative regulation of mononuclear cell proliferation |
0.004318 |
2.699 |
-- |
INHERITED FROM: negative regulation of B cell proliferation || negative regulation of lymphocyte proliferation |
| Biological Process (BP) |
cell migration |
0.002633 |
1.658 |
-- |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
leukocyte chemotaxis |
0.0157 |
2.398 |
-- |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
taxis |
0.7976 |
1.921 |
-- |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
cell motility |
0.006142 |
1.585 |
-- |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
cell chemotaxis |
0.002526 |
2.222 |
-- |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
granulocyte chemotaxis |
0.1898 |
2.398 |
-- |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
lymphocyte activation |
0.1486 |
1.699 |
-- |
INHERITED FROM: natural killer cell activation || T cell selection || T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response || alpha-beta T cell activation || alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response |
| Biological Process (BP) |
cellular process |
0.6389 |
0.1415 |
-- |
INHERITED FROM: natural killer cell activation || cell activation || cell activation involved in immune response || neutrophil chemotaxis || alpha-beta T cell activation || receptor biosynthetic process || T cell selection || cellular response to interleukin-18 || alpha-beta T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response || nucleocytoplasmic transport || cellular response to lipopolysaccharide || cell communication || type I interferon-mediated signaling pathway || protein import into nucleus || peptidyl-tyrosine modification || peptide hormone secretion || intracellular protein kinase cascade || neutrophil apoptotic process || nuclear import || positive regulation of astrocyte differentiation || endoplasmic reticulum unfolded protein response || cell death || cellular response to type I interferon || peptidyl-tyrosine phosphorylation || inflammatory cell apoptotic process || cellular response to cytokine stimulus || protein targeting to nucleus || regulation of astrocyte differentiation || cytokine-mediated signaling pathway || T cell differentiation involved in immune response || protein localization to nucleus || nuclear transport || STAT protein import into nucleus || cellular response to growth hormone stimulus || leukocyte differentiation || myeloid cell apoptotic process || regulation of glial cell differentiation || cell-type specific apoptotic process || positive regulation of glial cell differentiation || cellular response to unfolded protein || cellular developmental process || JAK-STAT cascade || leukocyte apoptotic process || hormone secretion || tyrosine phosphorylation of Stat3 protein || leukocyte activation || cell differentiation || growth hormone receptor signaling pathway || myeloid cell differentiation || T cell activation involved in immune response || receptor metabolic process || programmed cell death |
| Biological Process (BP) |
generation of a signal involved in cell-cell signaling |
0.02387 |
1.921 |
-- |
INHERITED FROM: peptide hormone secretion || hormone secretion |
| Biological Process (BP) |
cell-cell signaling |
0.4192 |
1.357 |
-- |
INHERITED FROM: peptide hormone secretion || hormone secretion |
| Biological Process (BP) |
secretion by cell |
0.3195 |
1.699 |
-- |
INHERITED FROM: peptide hormone secretion || hormone secretion |
| Biological Process (BP) |
cellular response to organic substance |
0.1831 |
1.208 |
-- |
INHERITED FROM: cytokine-mediated signaling pathway || cellular response to type I interferon || cellular response to lipopolysaccharide || cellular response to unfolded protein || cellular response to interleukin-18 || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || type I interferon-mediated signaling pathway || cellular response to cytokine stimulus || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.255 |
1.237 |
-- |
INHERITED FROM: cytokine-mediated signaling pathway || growth hormone receptor signaling pathway || type I interferon-mediated signaling pathway |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2708 |
-- |
INHERITED FROM: peptidyl-tyrosine phosphorylation || receptor biosynthetic process || peptidyl-tyrosine modification || tyrosine phosphorylation of Stat3 protein || receptor metabolic process |
| Biological Process (BP) |
metabolic process |
1 |
0.2411 |
-- |
INHERITED FROM: peptidyl-tyrosine phosphorylation || receptor biosynthetic process || cholesterol metabolic process || peptidyl-tyrosine modification || tyrosine phosphorylation of Stat3 protein || receptor metabolic process |
| Biological Process (BP) |
organic substance metabolic process |
1 |
0.2676 |
-- |
INHERITED FROM: peptidyl-tyrosine phosphorylation || receptor biosynthetic process || cholesterol metabolic process || peptidyl-tyrosine modification || tyrosine phosphorylation of Stat3 protein || receptor metabolic process |
| Biological Process (BP) |
macromolecule metabolic process |
1 |
0.4634 |
-- |
INHERITED FROM: peptidyl-tyrosine phosphorylation || peptidyl-tyrosine modification || tyrosine phosphorylation of Stat3 protein || receptor biosynthetic process || receptor metabolic process |
| Biological Process (BP) |
primary metabolic process |
1 |
0.2976 |
-- |
INHERITED FROM: peptidyl-tyrosine phosphorylation || peptidyl-tyrosine modification || tyrosine phosphorylation of Stat3 protein || cholesterol metabolic process |
| Biological Process (BP) |
single-organism transport |
1 |
0.8013 |
-- |
INHERITED FROM: peptide transport || peptide secretion || hormone transport || STAT protein import into nucleus || protein import into nucleus || nuclear import || protein import || peptide hormone secretion || protein targeting to nucleus || amide transport || hormone secretion |
| Biological Process (BP) |
regulation of carbohydrate metabolic process |
0.0564 |
2.097 |
-- |
INHERITED FROM: regulation of glucose metabolic process |
| Biological Process (BP) |
regulation of signal transduction |
0.9727 |
1.119 |
-- |
INHERITED FROM: regulation of intracellular protein kinase cascade || regulation of JAK-STAT cascade || positive regulation of small GTPase mediated signal transduction || regulation of tyrosine phosphorylation of STAT protein || positive regulation of signal transduction || regulation of cytokine-mediated signaling pathway || regulation of type I interferon-mediated signaling pathway || positive regulation of Ras protein signal transduction || positive regulation of tyrosine phosphorylation of STAT protein || positive regulation of intracellular protein kinase cascade || positive regulation of JAK-STAT cascade || regulation of Ras protein signal transduction |
| Biological Process (BP) |
regulation of epithelial cell migration |
0.5237 |
2.398 |
-- |
INHERITED FROM: regulation of endothelial cell migration || regulation of blood vessel endothelial cell migration |
| Biological Process (BP) |
behavior |
0.5279 |
1.357 |
-- |
INHERITED FROM: adult feeding behavior || feeding behavior |
| Biological Process (BP) |
lipid metabolic process |
1 |
0.9431 |
-- |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
small molecule metabolic process |
1 |
0.6421 |
-- |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
reproductive process |
0.05989 |
1.143 |
-- |
INHERITED FROM: female pregnancy || maternal process involved in female pregnancy || embryo implantation || multi-organism reproductive process |
| Biological Process (BP) |
transport |
1 |
0.7747 |
-- |
INHERITED FROM: nucleocytoplasmic transport || peptide transport || peptide secretion || hormone transport || nuclear transport || STAT protein import into nucleus || protein import into nucleus || nuclear import || protein import || peptide hormone secretion || protein targeting to nucleus || amide transport || hormone secretion |
| Biological Process (BP) |
establishment of localization |
1 |
0.7696 |
-- |
INHERITED FROM: nucleocytoplasmic transport || peptide transport || peptide secretion || hormone transport || nuclear transport || STAT protein import into nucleus || protein import into nucleus || nuclear import || protein import || peptide hormone secretion || protein targeting to nucleus || amide transport || hormone secretion |
| Biological Process (BP) |
protein targeting |
0.007515 |
1.585 |
-- |
INHERITED FROM: protein import into nucleus || protein targeting to nucleus || STAT protein import into nucleus |
| Biological Process (BP) |
intracellular protein transport |
0.0365 |
1.553 |
-- |
INHERITED FROM: protein import into nucleus || protein targeting to nucleus || STAT protein import into nucleus |
| Biological Process (BP) |
establishment of protein localization |
0.111 |
1.42 |
-- |
INHERITED FROM: protein import into nucleus || protein import || protein targeting to nucleus || STAT protein import into nucleus |
| Biological Process (BP) |
positive regulation of cell death |
0.001194 |
1.854 |
-- |
INHERITED FROM: positive regulation of B cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
positive regulation of programmed cell death |
0.01326 |
1.921 |
-- |
INHERITED FROM: positive regulation of B cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
regulation of leukocyte mediated immunity |
0.7408 |
1.854 |
-- |
INHERITED FROM: regulation of immunoglobulin mediated immune response || positive regulation of isotype switching || regulation of isotype switching || regulation of B cell mediated immunity || regulation of lymphocyte mediated immunity |
| Biological Process (BP) |
T cell differentiation |
0.6466 |
2.097 |
-- |
INHERITED FROM: CD8-positive, alpha-beta T cell differentiation involved in immune response || alpha-beta T cell differentiation involved in immune response || T cell selection || T cell differentiation involved in immune response |
| Biological Process (BP) |
lymphocyte activation involved in immune response |
0.001113 |
2.398 |
-- |
INHERITED FROM: CD8-positive, alpha-beta T cell differentiation involved in immune response || alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response || T cell differentiation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell activation involved in immune response |
0.002 |
2.699 |
-- |
INHERITED FROM: CD8-positive, alpha-beta T cell differentiation involved in immune response || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
alpha-beta T cell differentiation |
0.002213 |
2.222 |
-- |
INHERITED FROM: CD8-positive, alpha-beta T cell differentiation involved in immune response || alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
response to bacterium |
0.04565 |
1.658 |
-- |
INHERITED FROM: response to molecule of bacterial origin || response to lipopolysaccharide || cellular response to lipopolysaccharide |
| Biological Process (BP) |
positive regulation of cell adhesion |
0.05679 |
2.699 |
-- |
INHERITED FROM: positive regulation of cell-matrix adhesion |
| Biological Process (BP) |
regulation of cell-substrate adhesion |
0.002707 |
2.398 |
-- |
INHERITED FROM: regulation of cell-matrix adhesion || positive regulation of cell-matrix adhesion |
| Biological Process (BP) |
regulation of protein modification process |
0.891 |
1.377 |
-- |
INHERITED FROM: positive regulation of protein phosphorylation || positive regulation of tyrosine phosphorylation of STAT protein || regulation of peptidyl-tyrosine phosphorylation || positive regulation of protein modification process || regulation of tyrosine phosphorylation of STAT protein || regulation of protein phosphorylation || positive regulation of peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
in utero embryonic development |
0.01894 |
1.745 |
-- |
INHERITED FROM: embryonic placenta development |
| Biological Process (BP) |
embryo development |
1 |
1.301 |
-- |
INHERITED FROM: embryonic placenta development |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.3865 |
1.469 |
-- |
INHERITED FROM: embryonic placenta development |
| Biological Process (BP) |
myeloid cell homeostasis |
0.01791 |
1.854 |
-- |
INHERITED FROM: neutrophil homeostasis || neutrophil apoptotic process |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
1 |
1.027 |
-- |
INHERITED FROM: regulation of DNA recombination || positive regulation of isotype switching || positive regulation of RNA metabolic process || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nucleobase-containing compound metabolic process || regulation of DNA metabolic process || positive regulation of DNA recombination || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of transcription, DNA-dependent || regulation of isotype switching || positive regulation of DNA metabolic process |
| Biological Process (BP) |
multicellular organismal process |
1.186e-13 |
0.6091 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
4.503e-07 |
0.6904 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
0 |
0.5498 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
0.012 |
0.5317 |
Least Informative |
INHERITED FROM: positive regulation of B cell activation || positive regulation of nucleobase-containing compound metabolic process || negative regulation of cellular process || regulation of cytokine-mediated signaling pathway || positive regulation of myeloid leukocyte differentiation || positive regulation of interleukin-1 beta secretion || negative regulation of cytokine biosynthetic process || negative regulation of protein secretion || regulation of cell proliferation || negative regulation of cytokine secretion || positive regulation of protein modification process || regulation of cell migration || positive regulation of immunoglobulin secretion || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of JAK-STAT cascade || regulation of Ras protein signal transduction || positive regulation of natural killer cell differentiation || regulation of cell death || regulation of DNA recombination || positive regulation of cellular biosynthetic process || regulation of cytokine secretion || positive regulation of leukocyte activation || regulation of cell communication || positive regulation of leukocyte differentiation || negative regulation of myeloid cell apoptotic process || regulation of CD4-positive, alpha-beta T cell differentiation || regulation of nitric oxide biosynthetic process || positive regulation of cellular process || positive regulation of cell differentiation || negative regulation of membrane protein ectodomain proteolysis || regulation of T-helper cell differentiation || regulation of phosphorylation || regulation of myeloid cell apoptotic process || regulation of phosphorus metabolic process || regulation of astrocyte differentiation || cytokine-mediated signaling pathway || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of small GTPase mediated signal transduction || regulation of tyrosine phosphorylation of STAT protein || positive regulation of phosphate metabolic process || negative regulation of leukocyte activation || negative regulation of cytokine secretion involved in immune response || negative regulation of B cell proliferation || positive regulation of myeloid cell differentiation || STAT protein import into nucleus || regulation of cell development || regulation of cellular protein metabolic process || positive regulation of peptidyl-tyrosine phosphorylation || regulation of leukocyte activation || negative regulation of cellular catabolic process || positive regulation of protein phosphorylation || regulation of myeloid cell differentiation || regulation of glial cell differentiation || regulation of cytokine biosynthetic process || regulation of phosphate metabolic process || positive regulation of cell communication || regulation of T-helper 17 cell differentiation || regulation of cellular catabolic process || regulation of cell differentiation || negative regulation of leukocyte proliferation || regulation of meiosis || positive regulation of Ras protein signal transduction || positive regulation of cell-matrix adhesion || regulation of membrane protein ectodomain proteolysis || regulation of leukocyte proliferation || positive regulation of lymphocyte apoptotic process || positive regulation of glial cell differentiation || positive regulation of monocyte differentiation || regulation of chemokine biosynthetic process || regulation of T cell homeostatic proliferation || regulation of CD4-positive, alpha-beta T cell activation || positive regulation of RNA metabolic process || regulation of peptidyl-tyrosine phosphorylation || regulation of interleukin-1 beta secretion || positive regulation of signal transduction || positive regulation of phosphorylation || regulation of leukocyte apoptotic process || positive regulation of tyrosine phosphorylation of STAT protein || positive regulation of nitric oxide biosynthetic process || negative regulation of mast cell apoptotic process || type I interferon-mediated signaling pathway || regulation of lymphocyte proliferation || regulation of B cell activation || JAK-STAT cascade || positive regulation of B cell apoptotic process || positive regulation of isotype switching || regulation of JAK-STAT cascade || positive regulation of cell proliferation || positive regulation of leukocyte proliferation || negative regulation of lymphocyte activation || regulation of cell-matrix adhesion || intracellular protein kinase cascade || positive regulation of cellular protein metabolic process || positive regulation of transcription, DNA-dependent || positive regulation of protein secretion || regulation of protein phosphorylation || negative regulation of proteolysis || regulation of cell activation || tyrosine phosphorylation of Stat3 protein || negative regulation of cell proliferation || regulation of mast cell apoptotic process || negative regulation of B cell activation || regulation of myelination || positive regulation of phosphorus metabolic process || negative regulation of lymphocyte proliferation || regulation of B cell proliferation || regulation of protein secretion || negative regulation of myelination || negative regulation of cell death || negative regulation of cell activation || regulation of DNA metabolic process || negative regulation of meiosis || positive regulation of intracellular protein kinase cascade || regulation of B cell apoptotic process || growth hormone receptor signaling pathway || positive regulation of T cell proliferation || regulation of cellular metabolic process || positive regulation of leukocyte apoptotic process || positive regulation of interleukin-6 biosynthetic process || regulation of blood vessel endothelial cell migration || regulation of intracellular protein kinase cascade || regulation of cytokine secretion involved in immune response || positive regulation of astrocyte differentiation || negative regulation of hormone secretion || regulation of meiotic cell cycle || regulation of cellular localization || regulation of type I interferon-mediated signaling pathway || positive regulation of DNA recombination || positive regulation of cell activation || regulation of leukocyte differentiation || regulation of glucose metabolic process || regulation of isotype switching || positive regulation of cellular metabolic process || endoplasmic reticulum unfolded protein response || positive regulation of DNA metabolic process || regulation of endothelial cell migration |
| Biological Process (BP) |
cellular macromolecule metabolic process |
1 |
0.4976 |
Least Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || receptor biosynthetic process || peptidyl-tyrosine phosphorylation || peptidyl-tyrosine modification || receptor metabolic process |
| Biological Process (BP) |
protein metabolic process |
1 |
0.6383 |
Least Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine phosphorylation || peptidyl-tyrosine modification |
| Biological Process (BP) |
biosynthetic process |
0.8314 |
0.52 |
Least Informative |
INHERITED FROM: receptor biosynthetic process |
| Biological Process (BP) |
regulation of metabolic process |
0.005838 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of proteolysis || regulation of MHC class II biosynthetic process || positive regulation of RNA metabolic process || regulation of steroid biosynthetic process || regulation of peptidyl-tyrosine phosphorylation || positive regulation of nucleobase-containing compound metabolic process || regulation of primary metabolic process || positive regulation of phosphorylation || positive regulation of gene expression || positive regulation of protein metabolic process || negative regulation of cytokine biosynthetic process || positive regulation of nitrogen compound metabolic process || positive regulation of tyrosine phosphorylation of STAT protein || positive regulation of protein modification process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || regulation of DNA recombination || positive regulation of macromolecule metabolic process || positive regulation of isotype switching || positive regulation of cellular biosynthetic process || positive regulation of biosynthetic process || regulation of transferase activity || negative regulation of catabolic process || positive regulation of cellular protein metabolic process || regulation of nitric oxide biosynthetic process || positive regulation of macromolecule biosynthetic process || positive regulation of MHC class II biosynthetic process || positive regulation of transcription, DNA-dependent || negative regulation of membrane protein ectodomain proteolysis || regulation of protein phosphorylation || negative regulation of proteolysis || regulation of phosphorylation || regulation of phosphorus metabolic process || regulation of sequence-specific DNA binding transcription factor activity || regulation of protein metabolic process || regulation of tyrosine phosphorylation of STAT protein || positive regulation of phosphorus metabolic process || positive regulation of phosphate metabolic process || negative regulation of protein catabolic process || regulation of DNA metabolic process || regulation of catabolic process || positive regulation of transferase activity || regulation of cellular protein metabolic process || regulation of cellular metabolic process || positive regulation of peptidyl-tyrosine phosphorylation || negative regulation of cellular catabolic process || positive regulation of interleukin-6 biosynthetic process || positive regulation of protein phosphorylation || regulation of cytokine biosynthetic process || regulation of phosphate metabolic process || regulation of cellular catabolic process || regulation of protein catabolic process || regulation of membrane protein ectodomain proteolysis || positive regulation of DNA recombination || positive regulation of metabolic process || regulation of chemokine biosynthetic process || regulation of glucose metabolic process || regulation of isotype switching || positive regulation of cellular metabolic process || regulation of macromolecule metabolic process || positive regulation of DNA metabolic process |
| Biological Process (BP) |
single-organism cellular process |
0.001136 |
0.3915 |
Least Informative |
INHERITED FROM: natural killer cell activation || cell death || cell activation || cellular response to type I interferon || inflammatory cell apoptotic process || cellular response to cytokine stimulus || cell activation involved in immune response || neutrophil chemotaxis || protein targeting to nucleus || regulation of astrocyte differentiation || cytokine-mediated signaling pathway || T cell differentiation involved in immune response || alpha-beta T cell activation || protein localization to nucleus || nuclear transport || STAT protein import into nucleus || cellular response to growth hormone stimulus || leukocyte differentiation || T cell selection || myeloid cell apoptotic process || regulation of glial cell differentiation || cell-type specific apoptotic process || cellular response to interleukin-18 || alpha-beta T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response || positive regulation of glial cell differentiation || cellular response to unfolded protein || nucleocytoplasmic transport || cellular developmental process || cellular response to lipopolysaccharide || cell communication || type I interferon-mediated signaling pathway || JAK-STAT cascade || protein import into nucleus || leukocyte apoptotic process || peptide hormone secretion || intracellular protein kinase cascade || hormone secretion || tyrosine phosphorylation of Stat3 protein || leukocyte activation || cell differentiation || growth hormone receptor signaling pathway || myeloid cell differentiation || neutrophil apoptotic process || nuclear import || T cell activation involved in immune response || positive regulation of astrocyte differentiation || programmed cell death || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
single-organism metabolic process |
1 |
0.5376 |
Least Informative |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
organic cyclic compound metabolic process |
1 |
0.5817 |
Least Informative |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
localization |
1 |
0.6946 |
Least Informative |
INHERITED FROM: nucleocytoplasmic transport || protein localization to nucleus || peptide transport || peptide secretion || hormone transport || nuclear transport || STAT protein import into nucleus || protein import into nucleus || nuclear import || protein import || peptide hormone secretion || neutrophil chemotaxis || protein targeting to nucleus || amide transport || hormone secretion |
| Biological Process (BP) |
immune system process |
0 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to endogenous stimulus |
3.3e-05 |
1.237 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of metabolic process |
0 |
1.167 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to organic substance |
0 |
1.018 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell communication |
4.008e-15 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
0 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cell differentiation |
1.155e-08 |
1.009 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular metabolic process |
2.788e-05 |
0.7905 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
0 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
2.266e-07 |
0.7645 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organ development |
1.429e-07 |
0.9355 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
0 |
0.9066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular process |
3.864e-05 |
0.9355 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of response to stimulus |
0 |
0.9914 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of developmental process |
4.008e-15 |
1.155 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of multicellular organismal process |
0 |
0.9666 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein metabolic process |
0 |
1.119 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
multi-organism process |
0 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
response to oxygen-containing compound |
0.539 |
1.108 |
Moderately Informative |
INHERITED FROM: cellular response to lipopolysaccharide || cellular response to growth hormone stimulus || response to lipopolysaccharide || growth hormone receptor signaling pathway || response to peptide || response to growth hormone stimulus |
| Biological Process (BP) |
response to abiotic stimulus |
1 |
1.108 |
Moderately Informative |
INHERITED FROM: response to oxygen levels || response to decreased oxygen levels |
| Biological Process (BP) |
anatomical structure morphogenesis |
1 |
1.036 |
Moderately Informative |
INHERITED FROM: morphogenesis of a branching epithelium || gland morphogenesis || branching involved in mammary gland duct morphogenesis || morphogenesis of a branching structure || mammary gland duct morphogenesis || mammary duct terminal end bud growth |
| Biological Process (BP) |
tissue development |
1 |
1.143 |
Moderately Informative |
INHERITED FROM: adipose tissue development || morphogenesis of a branching epithelium || branching involved in mammary gland duct morphogenesis || mammary gland epithelium development || mammary gland duct morphogenesis || connective tissue development || mammary gland fat development || mammary duct terminal end bud growth |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: positive regulation of RNA metabolic process || regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nucleobase-containing compound metabolic process || positive regulation of nitrogen compound metabolic process || regulation of DNA metabolic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || regulation of DNA recombination || positive regulation of isotype switching || regulation of nitric oxide biosynthetic process || positive regulation of DNA recombination || positive regulation of transcription, DNA-dependent || regulation of isotype switching || positive regulation of DNA metabolic process |
| Biological Process (BP) |
cellular localization |
0.915 |
1.027 |
Moderately Informative |
INHERITED FROM: nuclear import || nucleocytoplasmic transport || protein localization to nucleus || peptide hormone secretion || nuclear transport || protein targeting to nucleus || STAT protein import into nucleus || protein import into nucleus || hormone secretion |
| Biological Process (BP) |
regulation of molecular function |
0.004603 |
1.056 |
Moderately Informative |
INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || regulation of transferase activity || positive regulation of transferase activity || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of molecular function |
| Biological Process (BP) |
regulation of gene expression |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of sequence-specific DNA binding transcription factor activity || positive regulation of gene expression || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
homeostatic process |
0.9348 |
1.086 |
Moderately Informative |
INHERITED FROM: homeostasis of number of cells || neutrophil homeostasis || neutrophil apoptotic process |
| Biological Process (BP) |
nervous system development |
1 |
1.194 |
Moderately Informative |
INHERITED FROM: regulation of astrocyte differentiation || regulation of glial cell differentiation || positive regulation of astrocyte differentiation || positive regulation of glial cell differentiation |
| Biological Process (BP) |
regulation of biosynthetic process |
0.3383 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of MHC class II biosynthetic process || regulation of steroid biosynthetic process || regulation of sequence-specific DNA binding transcription factor activity || negative regulation of cytokine biosynthetic process || positive regulation of sequence-specific DNA binding transcription factor activity || positive regulation of nitric oxide biosynthetic process || positive regulation of interleukin-6 biosynthetic process || regulation of cytokine biosynthetic process || positive regulation of cellular biosynthetic process || positive regulation of biosynthetic process || regulation of nitric oxide biosynthetic process || positive regulation of macromolecule biosynthetic process || positive regulation of MHC class II biosynthetic process || regulation of chemokine biosynthetic process || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
signal transduction |
0.2892 |
0.9914 |
Moderately Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || cytokine-mediated signaling pathway || intracellular protein kinase cascade || STAT protein import into nucleus || growth hormone receptor signaling pathway || type I interferon-mediated signaling pathway || endoplasmic reticulum unfolded protein response || JAK-STAT cascade |
| Biological Process (BP) |
cellular protein modification process |
1 |
0.9066 |
Moderately Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine modification || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
phosphate-containing compound metabolic process |
1 |
0.8182 |
Moderately Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
cellular response to stress |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: cellular response to unfolded protein || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
macromolecule localization |
0.7797 |
1.046 |
Moderately Informative |
INHERITED FROM: protein localization to nucleus || protein import || protein targeting to nucleus || STAT protein import into nucleus || protein import into nucleus |
| Biological Process (BP) |
negative regulation of metabolic process |
0.5133 |
1.222 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of cytokine biosynthetic process || negative regulation of catabolic process || negative regulation of protein catabolic process || negative regulation of membrane protein ectodomain proteolysis || negative regulation of proteolysis |
| Biological Process (BP) |
cellular response to chemical stimulus |
0.002157 |
1.097 |
Moderately Informative |
INHERITED FROM: cytokine-mediated signaling pathway || cellular response to unfolded protein || cellular response to interleukin-18 || cellular response to cytokine stimulus || cellular response to type I interferon || cellular response to lipopolysaccharide || neutrophil chemotaxis || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || type I interferon-mediated signaling pathway || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
organic substance transport |
0.1573 |
0.9747 |
Moderately Informative |
INHERITED FROM: protein import || peptide transport || peptide hormone secretion || peptide secretion || protein targeting to nucleus || STAT protein import into nucleus || protein import into nucleus |
| Biological Process (BP) |
organic hydroxy compound metabolic process |
0.2549 |
1.208 |
Moderately Informative |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
reproduction |
0.2069 |
1.097 |
Moderately Informative |
INHERITED FROM: female pregnancy || maternal process involved in female pregnancy || embryo implantation || multi-organism reproductive process |
| Biological Process (BP) |
cell activation |
0 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine production |
0 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein phosphorylation |
4.768e-05 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of immune system process |
2.287e-09 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of immune effector process |
5.43e-14 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
nucleocytoplasmic transport |
0.0001275 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
defense response |
0 |
1.357 |
Informative |
DIRECT |
| Biological Process (BP) |
immune response |
1.114e-08 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
cell proliferation |
3.037e-09 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
response to wounding |
6.117e-14 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of signal transduction |
3.079e-10 |
1.377 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule biosynthetic process |
3.273e-07 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of phosphorus metabolic process |
0 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
2.268e-10 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of gene expression |
1.061e-06 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular biosynthetic process |
1.328e-05 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular catabolic process |
9.362e-05 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein localization |
3.021e-08 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
response to lipid |
2.275e-07 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
response to cytokine stimulus |
1.471e-09 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell proliferation |
0 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
multi-organism reproductive process |
9.621e-08 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
hematopoietic or lymphoid organ development |
0 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
gland development |
5.367e-05 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of immune response |
4.21e-14 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of body fluid levels |
9.877e-07 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of secretion |
0 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transport |
1.387e-10 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of developmental process |
1.186e-11 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of nitrogen compound metabolic process |
4.818e-07 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
3.983e-08 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of protein metabolic process |
8.676e-14 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
response to other organism |
2.457e-08 |
1.398 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell development |
4.125e-06 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell death |
0.00014 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic process |
0.004221 |
1.337 |
Informative |
INHERITED FROM: regulation of leukocyte apoptotic process || regulation of myeloid cell apoptotic process || negative regulation of mast cell apoptotic process || negative regulation of myeloid cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of B cell apoptotic process || regulation of mast cell apoptotic process || regulation of B cell apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
apoptotic process |
0.8945 |
1.553 |
Informative |
INHERITED FROM: cell-type specific apoptotic process || leukocyte apoptotic process || inflammatory cell apoptotic process || myeloid cell apoptotic process || neutrophil apoptotic process |
| Biological Process (BP) |
response to organic nitrogen |
1 |
1.495 |
Informative |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to peptide || response to growth hormone stimulus |
| Biological Process (BP) |
cellular response to oxygen-containing compound |
0.1639 |
1.319 |
Informative |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || cellular response to lipopolysaccharide |
| Biological Process (BP) |
cellular response to endogenous stimulus |
1 |
1.377 |
Informative |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway |
| Biological Process (BP) |
cellular response to nitrogen compound |
0.8129 |
1.658 |
Informative |
INHERITED FROM: cellular response to growth hormone stimulus || growth hormone receptor signaling pathway |
| Biological Process (BP) |
growth |
0.6432 |
1.523 |
Informative |
INHERITED FROM: mammary duct terminal end bud growth |
| Biological Process (BP) |
tissue morphogenesis |
0.5237 |
1.585 |
Informative |
INHERITED FROM: mammary gland duct morphogenesis || morphogenesis of a branching epithelium || mammary duct terminal end bud growth || branching involved in mammary gland duct morphogenesis |
| Biological Process (BP) |
epithelium development |
0.6029 |
1.377 |
Informative |
INHERITED FROM: mammary gland duct morphogenesis || morphogenesis of a branching epithelium || branching involved in mammary gland duct morphogenesis || mammary gland epithelium development || mammary duct terminal end bud growth |
| Biological Process (BP) |
tube development |
0.331 |
1.62 |
Informative |
INHERITED FROM: mammary gland duct morphogenesis || mammary duct terminal end bud growth || branching involved in mammary gland duct morphogenesis |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
1 |
1.658 |
Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
multicellular organismal reproductive process |
0.5587 |
1.337 |
Informative |
INHERITED FROM: maternal process involved in female pregnancy |
| Biological Process (BP) |
response to hormone stimulus |
0.00201 |
1.469 |
Informative |
INHERITED FROM: response to glucocorticoid stimulus || cellular response to growth hormone stimulus || growth hormone receptor signaling pathway || response to growth hormone stimulus || response to steroid hormone stimulus || response to corticosteroid stimulus |
| Biological Process (BP) |
response to organic cyclic compound |
0.003593 |
1.523 |
Informative |
INHERITED FROM: response to glucocorticoid stimulus || response to steroid hormone stimulus || response to corticosteroid stimulus |
| Biological Process (BP) |
positive regulation of catalytic activity |
1 |
1.337 |
Informative |
INHERITED FROM: positive regulation of transferase activity |
| Biological Process (BP) |
cytoplasmic transport |
0.04036 |
1.337 |
Informative |
INHERITED FROM: nuclear import || protein import into nucleus || STAT protein import into nucleus |
| Biological Process (BP) |
regulation of lipid metabolic process |
0.4989 |
1.745 |
Informative |
INHERITED FROM: regulation of steroid biosynthetic process |
| Biological Process (BP) |
generation of neurons |
0.007593 |
1.469 |
Informative |
INHERITED FROM: regulation of astrocyte differentiation || regulation of glial cell differentiation || positive regulation of glial cell differentiation || positive regulation of astrocyte differentiation |
| Biological Process (BP) |
regulation of reproductive process |
0.3719 |
1.745 |
Informative |
INHERITED FROM: negative regulation of meiosis || regulation of meiotic cell cycle || regulation of meiosis |
| Biological Process (BP) |
regulation of cell cycle process |
0.5523 |
1.553 |
Informative |
INHERITED FROM: negative regulation of meiosis || regulation of meiosis |
| Biological Process (BP) |
regulation of growth |
0.001155 |
1.42 |
Informative |
INHERITED FROM: regulation of growth of symbiont in host || negative regulation of growth of symbiont involved in interaction with host || negative regulation of growth of symbiont in host || modulation of growth of symbiont involved in interaction with host |
| Biological Process (BP) |
regulation of locomotion |
0.008063 |
1.745 |
Informative |
INHERITED FROM: regulation of blood vessel endothelial cell migration || regulation of cell migration || regulation of endothelial cell migration |
| Biological Process (BP) |
regulation of cellular component movement |
0.01801 |
1.699 |
Informative |
INHERITED FROM: regulation of blood vessel endothelial cell migration || regulation of cell migration || regulation of endothelial cell migration |
| Biological Process (BP) |
peptidyl-amino acid modification |
0.1029 |
1.377 |
Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine modification || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
protein phosphorylation |
0.5927 |
1.585 |
Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || peptidyl-tyrosine phosphorylation |
| Biological Process (BP) |
intracellular signal transduction |
0.2478 |
1.398 |
Informative |
INHERITED FROM: tyrosine phosphorylation of Stat3 protein || intracellular protein kinase cascade || JAK-STAT cascade || STAT protein import into nucleus |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
1 |
1.42 |
Informative |
INHERITED FROM: positive regulation of odontogenesis of dentin-containing tooth || positive regulation of odontogenesis || regulation of odontogenesis of dentin-containing tooth || regulation of odontogenesis |
| Biological Process (BP) |
negative regulation of protein metabolic process |
0.001937 |
1.523 |
Informative |
INHERITED FROM: negative regulation of protein catabolic process || negative regulation of membrane protein ectodomain proteolysis || negative regulation of proteolysis || negative regulation of cytokine biosynthetic process |
| Biological Process (BP) |
negative regulation of biosynthetic process |
1 |
1.62 |
Informative |
INHERITED FROM: negative regulation of cytokine biosynthetic process |
| Biological Process (BP) |
protein localization to organelle |
0.005418 |
1.523 |
Informative |
INHERITED FROM: protein localization to nucleus || protein import into nucleus || STAT protein import into nucleus |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.5714 |
1.585 |
Informative |
INHERITED FROM: negative regulation of appetite || negative regulation of response to food || negative regulation of response to external stimulus || negative regulation of response to nutrient levels |
| Biological Process (BP) |
regulation of response to external stimulus |
0.02968 |
1.469 |
Informative |
INHERITED FROM: negative regulation of appetite || negative regulation of response to food || regulation of response to food || negative regulation of response to external stimulus || negative regulation of response to nutrient levels |
| Biological Process (BP) |
response to external stimulus |
0.9217 |
1.319 |
Informative |
INHERITED FROM: regulation of appetite || negative regulation of appetite || response to nutrient levels || neutrophil chemotaxis |
| Biological Process (BP) |
regulation of nervous system development |
1 |
1.658 |
Informative |
INHERITED FROM: regulation of myelination || regulation of astrocyte differentiation || regulation of glial cell differentiation || positive regulation of astrocyte differentiation || negative regulation of myelination || positive regulation of glial cell differentiation |
| Biological Process (BP) |
regulation of system process |
1 |
1.553 |
Informative |
INHERITED FROM: regulation of myelination || negative regulation of myelination |
| Biological Process (BP) |
regulation of response to stress |
0.4515 |
1.42 |
Informative |
INHERITED FROM: regulation of defense response || regulation of type I interferon-mediated signaling pathway || regulation of defense response to virus by host |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.3226 |
1.301 |
Informative |
INHERITED FROM: negative regulation of cellular catabolic process || negative regulation of cytokine biosynthetic process || negative regulation of membrane protein ectodomain proteolysis || negative regulation of proteolysis |
| Biological Process (BP) |
cellular component movement |
0.1381 |
1.398 |
Informative |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
locomotion |
0.2863 |
1.444 |
Informative |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
localization of cell |
0.006298 |
1.585 |
Informative |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
regulation of hormone levels |
0.6324 |
1.523 |
Informative |
INHERITED FROM: hormone transport || peptide hormone secretion || hormone secretion |
| Biological Process (BP) |
single-organism behavior |
0.5676 |
1.523 |
Informative |
INHERITED FROM: adult feeding behavior |
| Biological Process (BP) |
alcohol metabolic process |
0.04481 |
1.377 |
Informative |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
steroid metabolic process |
0.025 |
1.745 |
Informative |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
single organism reproductive process |
0.1795 |
1.377 |
Informative |
INHERITED FROM: embryo implantation || maternal process involved in female pregnancy |
| Biological Process (BP) |
protein transport |
0.2101 |
1.469 |
Informative |
INHERITED FROM: protein import into nucleus || protein import || protein targeting to nucleus || STAT protein import into nucleus |
| Biological Process (BP) |
nitrogen compound transport |
0.3679 |
1.377 |
Informative |
INHERITED FROM: peptide secretion || amide transport || peptide transport || peptide hormone secretion |
| Biological Process (BP) |
secretion |
0.1148 |
1.469 |
Informative |
INHERITED FROM: peptide secretion || peptide hormone secretion || hormone secretion |
| Biological Process (BP) |
immune effector process |
0.07209 |
1.658 |
Informative |
INHERITED FROM: T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response || alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response || defense response to virus || cell activation involved in immune response |
| Biological Process (BP) |
chordate embryonic development |
0.1961 |
1.495 |
Informative |
INHERITED FROM: embryonic placenta development |
| Biological Process (BP) |
embryonic organ development |
0.0412 |
1.699 |
Informative |
INHERITED FROM: embryonic placenta development |
| Biological Process (BP) |
positive regulation of cytokine production |
0.0001998 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
embryonic placenta development |
9.755e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of immune system process |
0 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of immune effector process |
3.349e-07 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte mediated immunity |
0 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of adaptive immune response based on somatic recombination of immune receptors built from |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
inflammatory response |
8.033e-07 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
hemostasis |
0.0008344 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
feeding behavior |
1.28e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell proliferation |
1.738e-09 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to virus |
0.000197 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
hormone transport |
8.279e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein import |
9.91e-06 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
peptidyl-tyrosine phosphorylation |
1.911e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cytokine-mediated signaling pathway |
4.008e-15 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of proteolysis |
0.0001732 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular catabolic process |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell killing |
0.0001161 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to corticosteroid stimulus |
3.993e-08 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of response to external stimulus |
3.806e-10 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
response to lipopolysaccharide |
4.255e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein localization to nucleus |
3.713e-06 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cytokine biosynthetic process |
5.326e-10 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein catabolic process |
4.52e-07 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
amide transport |
0.0005527 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of multi-organism process |
6.798e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
multi-multicellular organism process |
9.999e-05 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein targeting to nucleus |
6.846e-07 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of nitric oxide biosynthetic process |
5.45e-10 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell differentiation |
0 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of myeloid cell differentiation |
1.186e-13 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of Ras protein signal transduction |
3.544e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein secretion |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of peptidyl-tyrosine phosphorylation |
0 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of steroid biosynthetic process |
4.449e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
coagulation |
3.316e-08 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell activation |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of secretion |
8.706e-12 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of secretion |
2.417e-08 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of DNA metabolic process |
2.644e-11 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of sequence-specific DNA binding transcription factor activity |
1.909e-11 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nuclear import |
8.567e-07 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of protein transport |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of protein transport |
0.0003433 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of multicellular organismal process |
2.442e-14 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
morphogenesis of a branching epithelium |
1.27e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mammary gland epithelium development |
7.308e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
connective tissue development |
1.223e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
leukocyte proliferation |
1.664e-06 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of leukocyte proliferation |
2.743e-10 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of leukocyte differentiation |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of lymphocyte activation |
0.1084 |
2 |
Highly Informative |
INHERITED FROM: regulation of T-helper 17 cell differentiation || regulation of CD4-positive, alpha-beta T cell activation || negative regulation of B cell activation || positive regulation of isotype switching || regulation of isotype switching || negative regulation of lymphocyte proliferation || regulation of T cell homeostatic proliferation || positive regulation of T cell proliferation || regulation of B cell proliferation || negative regulation of B cell proliferation || regulation of B cell activation || regulation of lymphocyte proliferation || regulation of CD4-positive, alpha-beta T cell differentiation || regulation of T-helper cell differentiation || positive regulation of B cell activation || negative regulation of lymphocyte activation || positive regulation of natural killer cell differentiation |
| Biological Process (BP) |
cellular response to biotic stimulus |
0.01491 |
2.097 |
Highly Informative |
INHERITED FROM: cellular response to lipopolysaccharide |
| Biological Process (BP) |
epithelial tube morphogenesis |
0.6277 |
1.854 |
Highly Informative |
INHERITED FROM: mammary duct terminal end bud growth || mammary gland duct morphogenesis || branching involved in mammary gland duct morphogenesis |
| Biological Process (BP) |
developmental growth |
0.412 |
1.921 |
Highly Informative |
INHERITED FROM: mammary duct terminal end bud growth |
| Biological Process (BP) |
cellular response to peptide hormone stimulus |
0.2101 |
2 |
Highly Informative |
INHERITED FROM: growth hormone receptor signaling pathway || cellular response to growth hormone stimulus |
| Biological Process (BP) |
transmembrane receptor protein tyrosine kinase signaling pathway |
0.329 |
1.796 |
Highly Informative |
INHERITED FROM: growth hormone receptor signaling pathway |
| Biological Process (BP) |
regulation of innate immune response |
1 |
2.097 |
Highly Informative |
INHERITED FROM: regulation of type I interferon-mediated signaling pathway |
| Biological Process (BP) |
regulation of mononuclear cell proliferation |
1 |
2.222 |
Highly Informative |
INHERITED FROM: negative regulation of lymphocyte proliferation || regulation of T cell homeostatic proliferation || positive regulation of T cell proliferation || regulation of B cell proliferation || negative regulation of B cell proliferation || regulation of lymphocyte proliferation |
| Biological Process (BP) |
T cell activation |
0.9776 |
2 |
Highly Informative |
INHERITED FROM: alpha-beta T cell activation || alpha-beta T cell differentiation involved in immune response || T cell selection || T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response |
| Biological Process (BP) |
negative regulation of reproductive process |
0.01186 |
2 |
Highly Informative |
INHERITED FROM: negative regulation of meiosis |
| Biological Process (BP) |
regulation of organ morphogenesis |
0.367 |
2.222 |
Highly Informative |
INHERITED FROM: positive regulation of odontogenesis of dentin-containing tooth || regulation of odontogenesis || regulation of odontogenesis of dentin-containing tooth || positive regulation of odontogenesis |
| Biological Process (BP) |
response to topologically incorrect protein |
0.3934 |
2.097 |
Highly Informative |
INHERITED FROM: cellular response to unfolded protein || endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
innate immune response |
1 |
1.921 |
Highly Informative |
INHERITED FROM: response to type I interferon || type I interferon-mediated signaling pathway || cellular response to type I interferon |
| Biological Process (BP) |
negative regulation of apoptotic process |
0.8257 |
1.796 |
Highly Informative |
INHERITED FROM: negative regulation of myeloid cell apoptotic process || negative regulation of mast cell apoptotic process |
| Biological Process (BP) |
regulation of interleukin-1 production |
0.875 |
2.222 |
Highly Informative |
INHERITED FROM: regulation of interleukin-1 beta production || regulation of interleukin-1 beta secretion || positive regulation of interleukin-1 beta production || positive regulation of interleukin-1 beta secretion |
| Biological Process (BP) |
regulation of response to nutrient levels |
1 |
2.222 |
Highly Informative |
INHERITED FROM: negative regulation of appetite || regulation of response to food || negative regulation of response to food || negative regulation of response to nutrient levels |
| Biological Process (BP) |
regulation of ion homeostasis |
1 |
2 |
Highly Informative |
INHERITED FROM: negative regulation of myelination || regulation of myelination |
| Biological Process (BP) |
regulation of neurological system process |
0.2943 |
2 |
Highly Informative |
INHERITED FROM: regulation of myelination || negative regulation of myelination |
| Biological Process (BP) |
ER-nucleus signaling pathway |
0.0505 |
2.222 |
Highly Informative |
INHERITED FROM: endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
response to endoplasmic reticulum stress |
0.006367 |
1.921 |
Highly Informative |
INHERITED FROM: endoplasmic reticulum unfolded protein response |
| Biological Process (BP) |
chemotaxis |
1 |
1.921 |
Highly Informative |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
leukocyte migration |
0.1627 |
2.222 |
Highly Informative |
INHERITED FROM: neutrophil chemotaxis |
| Biological Process (BP) |
signal release |
0.02353 |
1.921 |
Highly Informative |
INHERITED FROM: peptide hormone secretion || hormone secretion |
| Biological Process (BP) |
regulation of cellular carbohydrate metabolic process |
0.03425 |
2.097 |
Highly Informative |
INHERITED FROM: regulation of glucose metabolic process |
| Biological Process (BP) |
adult behavior |
0.0136 |
2 |
Highly Informative |
INHERITED FROM: adult feeding behavior |
| Biological Process (BP) |
sterol metabolic process |
0.001815 |
1.921 |
Highly Informative |
INHERITED FROM: cholesterol metabolic process |
| Biological Process (BP) |
wound healing |
1 |
2 |
Highly Informative |
INHERITED FROM: blood coagulation |
| Biological Process (BP) |
positive regulation of apoptotic process |
0.02573 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of B cell apoptotic process || positive regulation of lymphocyte apoptotic process || positive regulation of leukocyte apoptotic process |
| Biological Process (BP) |
lymphocyte differentiation |
0.2426 |
1.854 |
Highly Informative |
INHERITED FROM: alpha-beta T cell differentiation involved in immune response || T cell selection || T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response |
| Biological Process (BP) |
leukocyte activation involved in immune response |
0.05898 |
2 |
Highly Informative |
INHERITED FROM: alpha-beta T cell differentiation involved in immune response || T cell differentiation involved in immune response || CD8-positive, alpha-beta T cell differentiation involved in immune response || T cell activation involved in immune response |
| Biological Process (BP) |
regulation of cell adhesion |
0.07274 |
2 |
Highly Informative |
INHERITED FROM: positive regulation of cell-matrix adhesion || regulation of cell-matrix adhesion |
| Biological Process (BP) |
leukocyte homeostasis |
0.001829 |
2.222 |
Highly Informative |
INHERITED FROM: neutrophil homeostasis || neutrophil apoptotic process |
| Molecular Function (MF) |
cytokine activity |
0 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
cytokine receptor binding |
0 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
hormone activity |
9.575e-06 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
growth factor activity |
2.303e-05 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
growth factor receptor binding |
0.0002272 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
0.4893 |
0 |
-- |
INHERITED FROM: interleukin-2 receptor binding || cytokine receptor binding || interferon-alpha/beta receptor binding || protein binding || interleukin-10 receptor binding || cytokine activity || receptor binding || growth factor activity || hormone activity || binding || growth factor receptor binding |
| Molecular Function (MF) |
binding |
0 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
protein binding |
0 |
0.77 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
receptor binding |
0 |
1.565 |
Informative |
DIRECT |
| Cellular Component (CC) |
extracellular region part |
0 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
1 |
0.08068 |
-- |
INHERITED FROM: secretory granule || external side of plasma membrane || cell surface |
| Cellular Component (CC) |
cell part |
1 |
0.08068 |
-- |
INHERITED FROM: secretory granule || external side of plasma membrane || cell surface |
| Cellular Component (CC) |
cellular_component |
0.007957 |
0 |
-- |
INHERITED FROM: secretory granule || extracellular space || external side of plasma membrane || extracellular region part || cell surface || extracellular region |
| Cellular Component (CC) |
intracellular |
1 |
0.1266 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
cytoplasmic membrane-bounded vesicle |
0.02836 |
1.241 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
cytoplasmic vesicle |
0.05739 |
1.18 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
membrane-bounded vesicle |
0.04115 |
1.219 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
organelle |
1 |
0.1836 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
membrane-bounded organelle |
1 |
0.2912 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
intracellular organelle |
1 |
0.1875 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
intracellular part |
1 |
0.1266 |
-- |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
membrane part |
0.6663 |
0.6842 |
-- |
INHERITED FROM: external side of plasma membrane |
| Cellular Component (CC) |
plasma membrane part |
0.09576 |
1.036 |
-- |
INHERITED FROM: external side of plasma membrane |
| Cellular Component (CC) |
cell periphery |
1 |
0.8256 |
-- |
INHERITED FROM: external side of plasma membrane |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
1 |
0.2961 |
Least Informative |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2605 |
Least Informative |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
membrane |
1 |
0.5731 |
Least Informative |
INHERITED FROM: external side of plasma membrane |
| Cellular Component (CC) |
extracellular region |
0 |
0.9505 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
vesicle |
0.09191 |
1.144 |
Moderately Informative |
INHERITED FROM: secretory granule |
| Cellular Component (CC) |
plasma membrane |
0.9764 |
0.9734 |
Moderately Informative |
INHERITED FROM: external side of plasma membrane |
| Cellular Component (CC) |
extracellular space |
0 |
1.395 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell surface |
9.48e-06 |
1.542 |
Informative |
DIRECT |
| Cellular Component (CC) |
secretory granule |
2.518e-07 |
1.542 |
Informative |
DIRECT |
| Cellular Component (CC) |
external side of plasma membrane |
3.206e-09 |
1.94 |
Highly Informative |
DIRECT |
0
14511776
