|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
cell morphogenesis involved in neuron differentiation |
0 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis |
0 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription from RNA polymerase II promoter |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
axon guidance |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transcription, DNA-dependent |
4.008e-15 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of RNA metabolic process |
7.835e-15 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of nucleobase-containing compound metabolic process |
3.329e-14 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biosynthetic process |
1.711e-13 |
1.495 |
-- |
DIRECT |
| Biological Process (BP) |
actin filament depolymerization |
2.213e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular component organization |
8.825e-12 |
0.6819 |
-- |
DIRECT |
| Biological Process (BP) |
actin filament capping |
2.01e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
2.743e-11 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of actin filament depolymerization |
6.339e-11 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein depolymerization |
1.641e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of actin filament depolymerization |
1.857e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biological process |
2.511e-10 |
0.8182 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of actin filament polymerization |
2.646e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
actin cytoskeleton organization |
2.895e-10 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
actin filament polymerization |
3.133e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein polymerization |
1.342e-09 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein complex assembly |
5.915e-09 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
neurogenesis |
1.179e-08 |
1.357 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
1.261e-08 |
1.237 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
1.387e-08 |
1.167 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein depolymerization |
1.657e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA metabolic process |
2.72e-08 |
1.131 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of wound healing |
2.762e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of protein complex disassembly |
3.425e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of epithelial cell migration |
3.589e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein depolymerization |
3.672e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
actin filament severing |
4.764e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
6.678e-08 |
1.119 |
-- |
DIRECT |
| Biological Process (BP) |
neuron differentiation |
9.697e-08 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
1.016e-07 |
1.066 |
-- |
DIRECT |
| Biological Process (BP) |
cellular developmental process |
1.379e-07 |
0.9666 |
-- |
DIRECT |
| Biological Process (BP) |
system development |
1.441e-07 |
0.8069 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
2.467e-07 |
1.009 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cytoskeleton organization |
2.587e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of actin filament polymerization |
2.67e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
response to chemical stimulus |
2.983e-07 |
0.8861 |
-- |
DIRECT |
| Biological Process (BP) |
taxis |
3.178e-07 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex subunit organization |
3.691e-07 |
1.194 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
3.768e-07 |
1.027 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of actin polymerization or depolymerization |
4.466e-07 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of actin filament length |
4.866e-07 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of epithelial cell migration |
5.692e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein polymerization |
6.506e-07 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
cell development |
6.749e-07 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
neuron development |
2.11e-06 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell shape |
3.921e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
multicellular organismal development |
5.986e-06 |
0.7496 |
-- |
DIRECT |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
9.392e-06 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell motility |
9.516e-06 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
anatomical structure development |
1.005e-05 |
0.7212 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of organelle organization |
1.283e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
3.677e-05 |
1.208 |
-- |
DIRECT |
| Biological Process (BP) |
cell part morphogenesis |
3.797e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein complex assembly |
4.362e-05 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex disassembly |
6.795e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cytoskeleton organization |
8.283e-05 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecular complex disassembly |
8.497e-05 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cell projection morphogenesis |
9.621e-05 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
response to growth factor stimulus |
0.0001265 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of actin filament-based process |
0.000216 |
2 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell migration |
0.0002571 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell motility |
0.000313 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
single-multicellular organism process |
0.0006052 |
0.6383 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
0.0006592 |
0.4486 |
-- |
DIRECT |
| Biological Process (BP) |
biological_process |
1 |
0 |
-- |
INHERITED FROM: positive regulation of cell motility || positive regulation of nucleobase-containing compound metabolic process || cellular component organization or biogenesis || regulation of nucleobase-containing compound metabolic process || cell development || chemotaxis || regulation of actin filament-based process || positive regulation of macromolecule metabolic process || protein complex disassembly || regulation of anatomical structure size || negative regulation of organelle organization || cell projection organization || multicellular organismal process || axonogenesis || cell projection morphogenesis || generation of neurons || regulation of actin cytoskeleton organization || regulation of RNA biosynthetic process || positive regulation of metabolic process || negative regulation of protein complex assembly || cell morphogenesis involved in differentiation || regulation of protein polymerization || regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly || system development || response to chemical stimulus || positive regulation of transcription, DNA-dependent || actin filament depolymerization || regulation of cell shape || regulation of actin filament polymerization || positive regulation of cellular metabolic process || regulation of lamellipodium morphogenesis || anatomical structure morphogenesis || developmental process || negative regulation of protein depolymerization || regulation of cellular macromolecule biosynthetic process || positive regulation of cellular process || negative regulation of actin filament polymerization || multicellular organismal development || neuron development || regulation of protein depolymerization || cellular component morphogenesis || regulation of actin filament depolymerization || protein depolymerization || negative regulation of cytoskeleton organization || regulation of biological process || actin filament-based process || positive regulation of cell migration || axon guidance || protein complex subunit organization || regulation of cellular component size || regulation of epithelial cell migration || positive regulation of macromolecule biosynthetic process || cell part morphogenesis || response to external stimulus || negative regulation of protein complex disassembly || regulation of actin nucleation || ERBB signaling pathway || regulation of transcription from RNA polymerase II promoter || cell differentiation || regulation of cellular biosynthetic process || protein polymerization || cell morphogenesis involved in neuron differentiation || regulation of cell motility || transmembrane receptor protein tyrosine kinase signaling pathway || regulation of RNA metabolic process || single-multicellular organism process || cellular response to epidermal growth factor stimulus || cellular component organization || actin filament organization || response to growth factor stimulus || cellular protein complex assembly || negative regulation of actin filament depolymerization || anatomical structure development || regulation of wound healing || positive regulation of biosynthetic process || regulation of macromolecule biosynthetic process || actin filament capping || cellular component disassembly || cellular macromolecular complex assembly || regulation of metabolic process || regulation of actin filament bundle assembly || regulation of cell projection organization || single-organism developmental process || regulation of protein complex disassembly || regulation of cell migration || positive regulation of cellular biosynthetic process || taxis || regulation of actin polymerization or depolymerization || cell morphogenesis || cellular response to growth factor stimulus || response to epidermal growth factor stimulus || regulation of protein complex assembly || positive regulation of epithelial cell migration || positive regulation of biological process || neuron differentiation || positive regulation of RNA metabolic process || positive regulation of cytoskeleton organization || macromolecular complex disassembly || actin filament severing || positive regulation of gene expression || positive regulation of nitrogen compound metabolic process || cellular developmental process || positive regulation of transcription from RNA polymerase II promoter || cellular protein complex disassembly || locomotion || cytoskeleton organization || actin cytoskeleton organization || nervous system development || actin filament polymerization || regulation of actin filament length || neurogenesis || regulation of transcription, DNA-dependent || regulation of gene expression || negative regulation of protein polymerization |
| Biological Process (BP) |
biological regulation |
0.002605 |
0.4202 |
-- |
INHERITED FROM: positive regulation of cell motility || positive regulation of nucleobase-containing compound metabolic process || regulation of nucleobase-containing compound metabolic process || regulation of actin filament-based process || positive regulation of macromolecule metabolic process || regulation of anatomical structure size || negative regulation of organelle organization || regulation of cell motility || transmembrane receptor protein tyrosine kinase signaling pathway || regulation of RNA metabolic process || regulation of actin cytoskeleton organization || regulation of RNA biosynthetic process || positive regulation of metabolic process || negative regulation of protein complex assembly || regulation of protein polymerization || regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly || negative regulation of actin filament depolymerization || regulation of wound healing || positive regulation of biosynthetic process || regulation of macromolecule biosynthetic process || actin filament capping || positive regulation of transcription, DNA-dependent || regulation of metabolic process || regulation of cell shape || regulation of actin filament bundle assembly || regulation of actin filament polymerization || regulation of cell projection organization || positive regulation of cellular metabolic process || regulation of protein complex disassembly || regulation of lamellipodium morphogenesis || regulation of cell migration || positive regulation of cellular biosynthetic process || regulation of actin polymerization or depolymerization || negative regulation of protein depolymerization || regulation of cellular macromolecule biosynthetic process || positive regulation of cellular process || negative regulation of actin filament polymerization || regulation of protein complex assembly || regulation of protein depolymerization || positive regulation of epithelial cell migration || positive regulation of biological process || positive regulation of RNA metabolic process || regulation of actin filament depolymerization || positive regulation of cytoskeleton organization || positive regulation of gene expression || negative regulation of cytoskeleton organization || regulation of biological process || positive regulation of nitrogen compound metabolic process || positive regulation of cell migration || positive regulation of transcription from RNA polymerase II promoter || regulation of cellular component size || regulation of epithelial cell migration || positive regulation of macromolecule biosynthetic process || negative regulation of protein complex disassembly || regulation of actin nucleation || ERBB signaling pathway || regulation of transcription from RNA polymerase II promoter || regulation of cellular biosynthetic process || regulation of actin filament length || regulation of transcription, DNA-dependent || regulation of gene expression || negative regulation of protein polymerization |
| Biological Process (BP) |
cellular response to organic substance |
0.08617 |
1.208 |
-- |
INHERITED FROM: cellular response to growth factor stimulus || cellular response to epidermal growth factor stimulus |
| Biological Process (BP) |
negative regulation of biological process |
1 |
0.8665 |
-- |
INHERITED FROM: negative regulation of cytoskeleton organization || negative regulation of actin filament depolymerization || actin filament capping || negative regulation of protein depolymerization || negative regulation of organelle organization || negative regulation of protein complex disassembly || negative regulation of actin filament polymerization || negative regulation of protein polymerization || negative regulation of protein complex assembly |
| Biological Process (BP) |
macromolecular complex assembly |
0.7046 |
1.252 |
-- |
INHERITED FROM: protein polymerization || cellular protein complex assembly || cellular macromolecular complex assembly || actin filament polymerization |
| Biological Process (BP) |
protein complex biogenesis |
0.0572 |
1.301 |
-- |
INHERITED FROM: protein polymerization || cellular protein complex assembly || actin filament polymerization |
| Biological Process (BP) |
protein complex assembly |
0.8765 |
1.319 |
-- |
INHERITED FROM: protein polymerization || cellular protein complex assembly || actin filament polymerization |
| Biological Process (BP) |
cellular component assembly |
0.8331 |
1.076 |
-- |
INHERITED FROM: protein polymerization || actin filament polymerization || cellular protein complex assembly || cellular macromolecular complex assembly |
| Biological Process (BP) |
regulation of primary metabolic process |
0.6876 |
0.7852 |
-- |
INHERITED FROM: positive regulation of RNA metabolic process || positive regulation of nucleobase-containing compound metabolic process || regulation of transcription from RNA polymerase II promoter || regulation of nucleobase-containing compound metabolic process || regulation of RNA metabolic process || regulation of transcription, DNA-dependent || positive regulation of transcription from RNA polymerase II promoter || regulation of RNA biosynthetic process || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0.6064 |
0.7959 |
-- |
INHERITED FROM: positive regulation of RNA metabolic process || positive regulation of gene expression || regulation of transcription from RNA polymerase II promoter || regulation of RNA metabolic process || positive regulation of macromolecule metabolic process || regulation of transcription, DNA-dependent || positive regulation of transcription from RNA polymerase II promoter || regulation of macromolecule biosynthetic process || regulation of cellular macromolecule biosynthetic process || positive regulation of macromolecule biosynthetic process || regulation of RNA biosynthetic process || positive regulation of transcription, DNA-dependent || regulation of gene expression |
| Biological Process (BP) |
cellular process |
0.3217 |
0.1415 |
-- |
INHERITED FROM: cell development || protein complex disassembly || negative regulation of organelle organization || cell projection organization || cell morphogenesis involved in neuron differentiation || axonogenesis || transmembrane receptor protein tyrosine kinase signaling pathway || cell projection morphogenesis || generation of neurons || cellular response to epidermal growth factor stimulus || actin filament organization || negative regulation of protein complex assembly || cell morphogenesis involved in differentiation || negative regulation of actin filament depolymerization || actin filament capping || cellular component disassembly || actin filament depolymerization || regulation of actin filament polymerization || regulation of actin polymerization or depolymerization || negative regulation of protein depolymerization || cell morphogenesis || cellular response to growth factor stimulus || negative regulation of actin filament polymerization || neuron development || cellular component morphogenesis || neuron differentiation || regulation of actin filament depolymerization || protein depolymerization || macromolecular complex disassembly || actin filament severing || negative regulation of cytoskeleton organization || cellular developmental process || actin filament-based process || axon guidance || regulation of cellular component size || cellular protein complex disassembly || cell part morphogenesis || negative regulation of protein complex disassembly || cytoskeleton organization || ERBB signaling pathway || actin cytoskeleton organization || cell differentiation || actin filament polymerization || regulation of actin filament length || neurogenesis || negative regulation of protein polymerization |
| Biological Process (BP) |
single-organism process |
0.04476 |
0.3316 |
-- |
INHERITED FROM: cell development || protein complex disassembly || negative regulation of organelle organization || cell projection organization || cell morphogenesis involved in neuron differentiation || axonogenesis || transmembrane receptor protein tyrosine kinase signaling pathway || cell projection morphogenesis || generation of neurons || single-multicellular organism process || cellular response to epidermal growth factor stimulus || actin filament organization || negative regulation of protein complex assembly || cell morphogenesis involved in differentiation || system development || negative regulation of actin filament depolymerization || actin filament capping || cellular component disassembly || actin filament depolymerization || regulation of actin filament polymerization || single-organism developmental process || regulation of actin polymerization or depolymerization || negative regulation of protein depolymerization || cell morphogenesis || cellular response to growth factor stimulus || negative regulation of actin filament polymerization || multicellular organismal development || neuron development || cellular component morphogenesis || neuron differentiation || regulation of actin filament depolymerization || protein depolymerization || macromolecular complex disassembly || actin filament severing || negative regulation of cytoskeleton organization || cellular developmental process || actin filament-based process || axon guidance || regulation of cellular component size || cellular protein complex disassembly || cell part morphogenesis || negative regulation of protein complex disassembly || cytoskeleton organization || ERBB signaling pathway || actin cytoskeleton organization || cell differentiation || nervous system development || actin filament polymerization || regulation of actin filament length || neurogenesis || negative regulation of protein polymerization |
| Biological Process (BP) |
cellular response to stimulus |
1 |
0.7645 |
-- |
INHERITED FROM: ERBB signaling pathway || cellular response to growth factor stimulus || transmembrane receptor protein tyrosine kinase signaling pathway || cellular response to epidermal growth factor stimulus |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.1716 |
1.237 |
-- |
INHERITED FROM: ERBB signaling pathway || transmembrane receptor protein tyrosine kinase signaling pathway |
| Biological Process (BP) |
signaling |
0.9309 |
0.8416 |
-- |
INHERITED FROM: ERBB signaling pathway || transmembrane receptor protein tyrosine kinase signaling pathway |
| Biological Process (BP) |
cell communication |
1 |
0.8477 |
-- |
INHERITED FROM: ERBB signaling pathway || transmembrane receptor protein tyrosine kinase signaling pathway |
| Biological Process (BP) |
single organism signaling |
1 |
0.8601 |
-- |
INHERITED FROM: ERBB signaling pathway || transmembrane receptor protein tyrosine kinase signaling pathway |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8539 |
-- |
INHERITED FROM: regulation of actin filament depolymerization || regulation of cell shape || negative regulation of actin filament polymerization || negative regulation of actin filament depolymerization || regulation of actin filament length || regulation of actin filament polymerization || actin filament capping || regulation of anatomical structure size || regulation of actin polymerization or depolymerization || regulation of cellular component size |
| Biological Process (BP) |
positive regulation of cellular component movement |
0.01206 |
1.854 |
-- |
INHERITED FROM: positive regulation of cell migration || positive regulation of cell motility || positive regulation of epithelial cell migration |
| Biological Process (BP) |
actin polymerization or depolymerization |
0.02788 |
2.398 |
-- |
INHERITED FROM: actin filament depolymerization || actin filament polymerization |
| Biological Process (BP) |
positive regulation of locomotion |
0.01212 |
1.854 |
-- |
INHERITED FROM: positive regulation of epithelial cell migration || positive regulation of cell migration || positive regulation of cell motility |
| Biological Process (BP) |
neuron projection development |
0.02052 |
1.921 |
-- |
INHERITED FROM: axonogenesis || axon guidance |
| Biological Process (BP) |
neuron projection morphogenesis |
0.1451 |
2 |
-- |
INHERITED FROM: axonogenesis || axon guidance |
| Biological Process (BP) |
cellular component organization or biogenesis |
4.174e-11 |
0.6536 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
5.138e-05 |
0.6904 |
Least Informative |
DIRECT |
| Biological Process (BP) |
multicellular organismal process |
0.0003507 |
0.6091 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of metabolic process |
0.000896 |
0.6946 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
0.07318 |
0.5317 |
Least Informative |
INHERITED FROM: positive regulation of cell motility || positive regulation of nucleobase-containing compound metabolic process || regulation of protein complex disassembly || regulation of lamellipodium morphogenesis || regulation of nucleobase-containing compound metabolic process || regulation of cell migration || regulation of actin filament-based process || positive regulation of cellular biosynthetic process || regulation of actin polymerization or depolymerization || negative regulation of protein depolymerization || regulation of cellular macromolecule biosynthetic process || positive regulation of cellular process || negative regulation of organelle organization || regulation of cell motility || transmembrane receptor protein tyrosine kinase signaling pathway || regulation of RNA metabolic process || negative regulation of actin filament polymerization || regulation of protein complex assembly || regulation of actin cytoskeleton organization || regulation of protein depolymerization || regulation of RNA biosynthetic process || positive regulation of epithelial cell migration || negative regulation of protein complex assembly || positive regulation of RNA metabolic process || regulation of actin filament depolymerization || positive regulation of cytoskeleton organization || negative regulation of cytoskeleton organization || regulation of protein polymerization || regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly || positive regulation of cell migration || negative regulation of actin filament depolymerization || positive regulation of transcription from RNA polymerase II promoter || actin filament capping || regulation of epithelial cell migration || positive regulation of transcription, DNA-dependent || regulation of cell shape || negative regulation of protein complex disassembly || regulation of actin nucleation || ERBB signaling pathway || regulation of transcription from RNA polymerase II promoter || regulation of actin filament bundle assembly || regulation of cellular biosynthetic process || regulation of actin filament length || regulation of transcription, DNA-dependent || regulation of actin filament polymerization || regulation of cell projection organization || positive regulation of cellular metabolic process || negative regulation of protein polymerization |
| Biological Process (BP) |
single-organism cellular process |
0.001892 |
0.3915 |
Least Informative |
INHERITED FROM: cell development || protein complex disassembly || regulation of actin polymerization or depolymerization || negative regulation of protein depolymerization || negative regulation of organelle organization || cell projection organization || cell morphogenesis involved in neuron differentiation || cell morphogenesis || cellular response to growth factor stimulus || axonogenesis || transmembrane receptor protein tyrosine kinase signaling pathway || negative regulation of actin filament polymerization || neuron development || cell projection morphogenesis || generation of neurons || cellular response to epidermal growth factor stimulus || cellular component morphogenesis || actin filament organization || negative regulation of protein complex assembly || neuron differentiation || regulation of actin filament depolymerization || protein depolymerization || macromolecular complex disassembly || actin filament severing || negative regulation of cytoskeleton organization || cell morphogenesis involved in differentiation || cellular developmental process || actin filament-based process || axon guidance || negative regulation of actin filament depolymerization || actin filament capping || regulation of cellular component size || cellular protein complex disassembly || cell part morphogenesis || cellular component disassembly || actin filament depolymerization || negative regulation of protein complex disassembly || cytoskeleton organization || ERBB signaling pathway || actin cytoskeleton organization || cell differentiation || actin filament polymerization || regulation of actin filament length || neurogenesis || regulation of actin filament polymerization || negative regulation of protein polymerization |
| Biological Process (BP) |
response to stimulus |
0.002111 |
0.5498 |
Least Informative |
INHERITED FROM: chemotaxis || axon guidance || taxis || response to chemical stimulus || response to external stimulus || ERBB signaling pathway || cellular response to growth factor stimulus || transmembrane receptor protein tyrosine kinase signaling pathway || response to epidermal growth factor stimulus || cellular response to epidermal growth factor stimulus || response to growth factor stimulus |
| Biological Process (BP) |
positive regulation of cellular process |
3.872e-12 |
0.9066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cell differentiation |
2.539e-09 |
1.009 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
anatomical structure morphogenesis |
2.853e-07 |
1.036 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of gene expression |
6.115e-07 |
0.9914 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
nervous system development |
2.341e-06 |
1.194 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of metabolic process |
8.246e-06 |
1.167 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
1.317e-05 |
0.7645 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
0.2009 |
1.066 |
Moderately Informative |
INHERITED FROM: positive regulation of cell motility || regulation of cell motility || positive regulation of cell migration || regulation of cell migration || regulation of epithelial cell migration || positive regulation of epithelial cell migration |
| Biological Process (BP) |
response to endogenous stimulus |
0.3292 |
1.237 |
Moderately Informative |
INHERITED FROM: cellular response to epidermal growth factor stimulus || response to epidermal growth factor stimulus |
| Biological Process (BP) |
response to organic substance |
1 |
1.018 |
Moderately Informative |
INHERITED FROM: cellular response to growth factor stimulus || cellular response to epidermal growth factor stimulus || response to growth factor stimulus || response to epidermal growth factor stimulus |
| Biological Process (BP) |
cellular response to chemical stimulus |
0.9979 |
1.097 |
Moderately Informative |
INHERITED FROM: cellular response to growth factor stimulus || cellular response to epidermal growth factor stimulus |
| Biological Process (BP) |
regulation of response to stimulus |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of wound healing |
| Biological Process (BP) |
macromolecular complex subunit organization |
0.1055 |
1.131 |
Moderately Informative |
INHERITED FROM: protein polymerization || actin filament depolymerization || protein depolymerization || protein complex subunit organization || actin filament polymerization || cellular protein complex disassembly || actin filament organization || macromolecular complex disassembly || cellular protein complex assembly || protein complex disassembly || cellular macromolecular complex assembly |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
0.02802 |
0.9914 |
Moderately Informative |
INHERITED FROM: positive regulation of RNA metabolic process || positive regulation of nucleobase-containing compound metabolic process || positive regulation of nitrogen compound metabolic process || regulation of transcription from RNA polymerase II promoter || regulation of nucleobase-containing compound metabolic process || regulation of RNA metabolic process || regulation of transcription, DNA-dependent || positive regulation of transcription from RNA polymerase II promoter || regulation of RNA biosynthetic process || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
regulation of cellular metabolic process |
0.01204 |
0.7905 |
Moderately Informative |
INHERITED FROM: positive regulation of RNA metabolic process || positive regulation of nucleobase-containing compound metabolic process || regulation of nucleobase-containing compound metabolic process || positive regulation of cellular biosynthetic process || positive regulation of transcription from RNA polymerase II promoter || regulation of cellular macromolecule biosynthetic process || positive regulation of transcription, DNA-dependent || regulation of transcription from RNA polymerase II promoter || regulation of RNA metabolic process || regulation of cellular biosynthetic process || regulation of transcription, DNA-dependent || regulation of RNA biosynthetic process || positive regulation of cellular metabolic process |
| Biological Process (BP) |
negative regulation of cellular process |
1 |
0.9355 |
Moderately Informative |
INHERITED FROM: negative regulation of protein complex disassembly || negative regulation of cytoskeleton organization || negative regulation of actin filament polymerization || negative regulation of actin filament depolymerization || actin filament capping || negative regulation of protein depolymerization || negative regulation of organelle organization || negative regulation of protein polymerization || negative regulation of protein complex assembly |
| Biological Process (BP) |
signal transduction |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: ERBB signaling pathway || transmembrane receptor protein tyrosine kinase signaling pathway |
| Biological Process (BP) |
regulation of cellular component organization |
0.1212 |
1.18 |
Moderately Informative |
INHERITED FROM: negative regulation of actin filament depolymerization || regulation of actin filament depolymerization || regulation of protein complex assembly || positive regulation of cytoskeleton organization || regulation of cell shape || negative regulation of protein complex disassembly || regulation of actin filament length || regulation of actin filament polymerization || regulation of actin nucleation || actin filament capping || negative regulation of cytoskeleton organization || regulation of actin polymerization or depolymerization || regulation of actin cytoskeleton organization || regulation of protein complex disassembly || negative regulation of protein depolymerization || regulation of cell projection organization || regulation of lamellipodium morphogenesis || regulation of protein depolymerization || regulation of protein polymerization || regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly || negative regulation of organelle organization || negative regulation of actin filament polymerization || regulation of actin filament bundle assembly || negative regulation of protein polymerization || negative regulation of protein complex assembly |
| Biological Process (BP) |
organelle organization |
0.06318 |
0.8996 |
Moderately Informative |
INHERITED FROM: actin filament depolymerization || actin filament polymerization || cytoskeleton organization || actin cytoskeleton organization || actin filament organization |
| Biological Process (BP) |
cellular component biogenesis |
1 |
0.983 |
Moderately Informative |
INHERITED FROM: actin filament polymerization || cellular protein complex assembly || protein polymerization || cellular macromolecular complex assembly |
| Biological Process (BP) |
regulation of multicellular organismal process |
0.4637 |
0.9666 |
Moderately Informative |
INHERITED FROM: regulation of epithelial cell migration || positive regulation of epithelial cell migration |
| Biological Process (BP) |
regulation of developmental process |
0.2159 |
1.155 |
Moderately Informative |
INHERITED FROM: regulation of cell shape || regulation of lamellipodium morphogenesis |
| Biological Process (BP) |
regulation of biosynthetic process |
0.01533 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || regulation of cellular biosynthetic process || positive regulation of cellular biosynthetic process || positive regulation of biosynthetic process || regulation of transcription, DNA-dependent || positive regulation of transcription from RNA polymerase II promoter || regulation of macromolecule biosynthetic process || regulation of cellular macromolecule biosynthetic process || positive regulation of macromolecule biosynthetic process || regulation of RNA biosynthetic process || positive regulation of transcription, DNA-dependent |
| Biological Process (BP) |
locomotion |
0 |
1.444 |
Informative |
DIRECT |
| Biological Process (BP) |
generation of neurons |
0 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
cell projection organization |
0 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of gene expression |
1.348e-14 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter |
3.156e-14 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule biosynthetic process |
3.329e-14 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of nitrogen compound metabolic process |
6.117e-14 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular biosynthetic process |
1.45e-13 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular component morphogenesis |
2.366e-12 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
response to external stimulus |
1.021e-11 |
1.319 |
Informative |
DIRECT |
| Biological Process (BP) |
actin filament-based process |
5.209e-08 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
cytoskeleton organization |
3.759e-07 |
1.301 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular component disassembly |
3.161e-05 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of anatomical structure size |
0.0001277 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecular complex assembly |
0.0007319 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular component organization |
0.001731 |
1.62 |
Informative |
INHERITED FROM: negative regulation of protein depolymerization || negative regulation of actin filament depolymerization || negative regulation of organelle organization || actin filament capping || negative regulation of cytoskeleton organization || negative regulation of actin filament polymerization || negative regulation of protein polymerization || negative regulation of protein complex assembly || negative regulation of protein complex disassembly |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.006836 |
1.377 |
Informative |
INHERITED FROM: cellular response to epidermal growth factor stimulus |
| Biological Process (BP) |
regulation of response to stress |
0.01264 |
1.42 |
Informative |
INHERITED FROM: regulation of wound healing |
| Biological Process (BP) |
positive regulation of cellular component organization |
0.02164 |
1.699 |
Informative |
INHERITED FROM: positive regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
0.002445 |
1.658 |
Informative |
INHERITED FROM: ERBB signaling pathway || transmembrane receptor protein tyrosine kinase signaling pathway |
| Biological Process (BP) |
regulation of organelle organization |
0.1013 |
1.495 |
Informative |
INHERITED FROM: negative regulation of actin filament depolymerization || regulation of actin filament depolymerization || positive regulation of cytoskeleton organization || regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly || regulation of actin filament length || regulation of actin filament polymerization || regulation of actin nucleation || negative regulation of organelle organization || actin filament capping || negative regulation of cytoskeleton organization || negative regulation of actin filament polymerization || regulation of actin filament bundle assembly || regulation of actin polymerization or depolymerization || regulation of actin cytoskeleton organization |
| Biological Process (BP) |
regulation of cellular component biogenesis |
0.008 |
1.658 |
Informative |
INHERITED FROM: regulation of actin filament polymerization || regulation of protein complex assembly || regulation of protein polymerization || actin filament capping || negative regulation of actin filament polymerization || regulation of actin filament bundle assembly || negative regulation of protein polymerization || negative regulation of protein complex assembly || positive regulation of actin filament bundle assembly |
| Biological Process (BP) |
regulation of cellular component movement |
0.008056 |
1.699 |
Informative |
INHERITED FROM: positive regulation of epithelial cell migration || positive regulation of cell migration || positive regulation of cell motility || regulation of cell migration || regulation of cell motility || regulation of epithelial cell migration |
| Biological Process (BP) |
regulation of locomotion |
0.008668 |
1.745 |
Informative |
INHERITED FROM: positive regulation of epithelial cell migration || positive regulation of cell migration || positive regulation of cell motility || regulation of cell migration || regulation of cell motility || regulation of epithelial cell migration |
| Biological Process (BP) |
regulation of anatomical structure morphogenesis |
0.109 |
1.42 |
Informative |
INHERITED FROM: regulation of cell shape || regulation of lamellipodium morphogenesis |
| Biological Process (BP) |
axonogenesis |
0 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
actin filament organization |
6.117e-14 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
chemotaxis |
8.81e-13 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein polymerization |
4.538e-09 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular protein complex disassembly |
8.106e-09 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell projection organization |
3.485e-08 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cytoskeleton organization |
2.128e-07 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein complex disassembly |
3.95e-06 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of actin cytoskeleton organization |
6.584e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell migration |
8.788e-06 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cellular response to growth factor stimulus |
0.0001008 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular component size |
0.0002329 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein complex assembly |
0.0002961 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
transmembrane receptor protein tyrosine kinase signaling pathway |
0.0003697 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell morphogenesis |
0.006156 |
1.854 |
Highly Informative |
INHERITED FROM: regulation of lamellipodium morphogenesis || regulation of cell shape |
| Biological Process (BP) |
positive regulation of organelle organization |
0.01137 |
2.097 |
Highly Informative |
INHERITED FROM: positive regulation of cytoskeleton organization || positive regulation of actin filament bundle assembly |
| Molecular Function (MF) |
actin binding |
0 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
long-chain fatty acid binding |
1.976e-13 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
cysteine-type endopeptidase inhibitor activity involved in apoptotic process |
3.613e-11 |
2.201 |
-- |
DIRECT |
| Molecular Function (MF) |
fatty acid binding |
1.559e-10 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
phosphatidylinositol phosphate binding |
2.174e-08 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
endopeptidase inhibitor activity |
4.477e-07 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
peptidase inhibitor activity |
5.371e-07 |
1.679 |
-- |
DIRECT |
| Molecular Function (MF) |
endopeptidase regulator activity |
5.508e-07 |
1.724 |
-- |
DIRECT |
| Molecular Function (MF) |
phospholipid binding |
1.023e-05 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
metal ion binding |
0.0005657 |
1.134 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
0.8876 |
0 |
-- |
INHERITED FROM: cation binding || phosphatidylinositol binding || cysteine-type endopeptidase inhibitor activity involved in apoptotic process || cytoskeletal protein binding || long-chain fatty acid binding || peptidase regulator activity || carboxylic acid binding || peptidase inhibitor activity || protein binding || enzyme inhibitor activity || phosphatidylinositol-4,5-bisphosphate binding || fatty acid binding || phosphatidylinositol phosphate binding || cysteine-type endopeptidase inhibitor activity || cysteine-type endopeptidase regulator activity involved in apoptotic process || phospholipid binding || actin binding || endopeptidase regulator activity || monocarboxylic acid binding || metal ion binding || binding || endopeptidase inhibitor activity || lysophosphatidic acid binding |
| Molecular Function (MF) |
ion binding |
0.3631 |
0.8334 |
-- |
INHERITED FROM: phosphatidylinositol binding || phospholipid binding || metal ion binding || long-chain fatty acid binding || carboxylic acid binding || cation binding || phosphatidylinositol phosphate binding || lysophosphatidic acid binding || fatty acid binding || phosphatidylinositol-4,5-bisphosphate binding || monocarboxylic acid binding |
| Molecular Function (MF) |
binding |
5.814e-05 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
protein binding |
0.0002124 |
0.77 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
cation binding |
0.0008161 |
1.099 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
enzyme regulator activity |
0.0054 |
1.134 |
Moderately Informative |
INHERITED FROM: cysteine-type endopeptidase regulator activity involved in apoptotic process || peptidase regulator activity || cysteine-type endopeptidase inhibitor activity || peptidase inhibitor activity || enzyme inhibitor activity || cysteine-type endopeptidase inhibitor activity involved in apoptotic process || endopeptidase regulator activity || endopeptidase inhibitor activity |
| Molecular Function (MF) |
anion binding |
0.2326 |
1.076 |
Moderately Informative |
INHERITED FROM: phosphatidylinositol binding || phospholipid binding || long-chain fatty acid binding || carboxylic acid binding || phosphatidylinositol phosphate binding || lysophosphatidic acid binding || fatty acid binding || phosphatidylinositol-4,5-bisphosphate binding || monocarboxylic acid binding |
| Molecular Function (MF) |
cytoskeletal protein binding |
0 |
1.423 |
Informative |
DIRECT |
| Molecular Function (MF) |
peptidase regulator activity |
1.461e-06 |
1.599 |
Informative |
DIRECT |
| Molecular Function (MF) |
carboxylic acid binding |
1.658e-06 |
1.599 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme inhibitor activity |
8.004e-06 |
1.474 |
Informative |
DIRECT |
| Molecular Function (MF) |
lipid binding |
0.00282 |
1.377 |
Informative |
INHERITED FROM: phosphatidylinositol phosphate binding || phosphatidylinositol binding || phospholipid binding || lysophosphatidic acid binding || fatty acid binding || phosphatidylinositol-4,5-bisphosphate binding || long-chain fatty acid binding |
| Molecular Function (MF) |
cysteine-type endopeptidase regulator activity involved in apoptotic process |
2.163e-10 |
2.076 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
cysteine-type endopeptidase inhibitor activity |
5.966e-10 |
2.076 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
monocarboxylic acid binding |
7.669e-09 |
1.9 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
phosphatidylinositol binding |
7.428e-07 |
1.98 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
non-membrane-bounded organelle |
0 |
0.6225 |
-- |
DIRECT |
| Cellular Component (CC) |
myofibril |
5.414e-09 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
microvillus |
9.66e-08 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
cell cortex part |
7.031e-07 |
1.696 |
-- |
DIRECT |
| Cellular Component (CC) |
contractile fiber |
1.14e-05 |
1.638 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
0.0004484 |
0.1836 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: myofibril || contractile fiber || cell cortex || cell cortex part |
| Cellular Component (CC) |
intracellular part |
0.02222 |
0.1266 |
-- |
INHERITED FROM: myofibril || contractile fiber || cytoskeleton || cell cortex part || actin cytoskeleton || intracellular non-membrane-bounded organelle || cell cortex |
| Cellular Component (CC) |
intracellular |
0.02721 |
0.1266 |
-- |
INHERITED FROM: myofibril || contractile fiber || cytoskeleton || cell cortex part || actin cytoskeleton || intracellular non-membrane-bounded organelle || cell cortex |
| Cellular Component (CC) |
intracellular organelle |
0.03162 |
0.1875 |
-- |
INHERITED FROM: myofibril || contractile fiber || cytoskeleton || actin cytoskeleton || intracellular non-membrane-bounded organelle |
| Cellular Component (CC) |
cell part |
0.03014 |
0.08068 |
-- |
INHERITED FROM: myofibril || cytoskeleton || cell cortex part || filopodium tip || microvillus || contractile fiber || filopodium || lamellipodium || cell leading edge || ruffle || actin cytoskeleton || intracellular non-membrane-bounded organelle || cell cortex |
| Cellular Component (CC) |
cell |
0.03039 |
0.08068 |
-- |
INHERITED FROM: myofibril || cytoskeleton || cell cortex part || filopodium tip || microvillus || contractile fiber || filopodium || lamellipodium || cell leading edge || ruffle || actin cytoskeleton || intracellular non-membrane-bounded organelle || cell cortex |
| Cellular Component (CC) |
cellular_component |
0.001652 |
0 |
-- |
INHERITED FROM: myofibril || cytoskeleton || cell cortex part || filopodium tip || microvillus || non-membrane-bounded organelle || contractile fiber || filopodium || lamellipodium || cell leading edge || ruffle || actin cytoskeleton || intracellular non-membrane-bounded organelle || organelle || cell cortex |
| Cellular Component (CC) |
cell periphery |
1 |
0.8256 |
-- |
INHERITED FROM: cell cortex || cell cortex part |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
0 |
0.6225 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2605 |
Least Informative |
INHERITED FROM: myofibril || contractile fiber || cell cortex || cell cortex part |
| Cellular Component (CC) |
cytoskeleton |
1.814e-08 |
1.036 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
cell projection |
0.00596 |
1.079 |
Moderately Informative |
INHERITED FROM: filopodium tip || filopodium || ruffle || lamellipodium || microvillus |
| Cellular Component (CC) |
actin cytoskeleton |
8.763e-09 |
1.428 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell cortex |
1.417e-06 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell leading edge |
0.0002371 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell projection part |
0.01114 |
1.337 |
Informative |
INHERITED FROM: filopodium tip |
| Cellular Component (CC) |
ruffle |
4.465e-05 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
lamellipodium |
0.0001423 |
1.763 |
Highly Informative |
DIRECT |
0
11977079
