SUPERFAMILY 1.75 HMM library and genome assignments server

CSL zinc finger superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Rubredoxin-like [ 57769] (17)
Superfamily:   CSL zinc finger [ 144217]
Families:   CSL zinc finger [ 144218] (2)

Superfamily statistics
Genomes (498) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 994 1,102 3
Proteins 992 1,100 3

Functional annotation
General category Regulation
Detailed category DNA-binding

Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)protein metabolic process0.00086580.0002492Least InformativeDirect
Biological Process (BP)biosynthetic process0.0025430.001144Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.0029040.003927Least InformativeInherited
Biological Process (BP)positive regulation of molecular function0.000057080.000005431Moderately InformativeDirect
Biological Process (BP)cellular protein modification process0.000046260.1374Moderately InformativeInherited
Biological Process (BP)peptidyl-amino acid modification0.000000036970.000000002281InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) protein metabolic process 0.0002492 Least Informative Direct
Biological Process (BP) biosynthetic process 0.001144 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.003927 Least Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.000005431 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 0.1374 Moderately Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.000000002281 Informative Direct
Molecular Function (MF) binding 0.4948 Least Informative Inherited
Molecular Function (MF) cation binding 0.00001779 Moderately Informative Direct
Molecular Function (MF) iron ion binding 0.00000000001541 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentNucleus0Least InformativeDirect
Cellular componentCytoplasm0.0000000000009905Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)biopolymer metabolism0Least InformativeDirect
UniPathway (UP)amino-acid metabolism0Least InformativeDirect
UniPathway (UP)nonprotein amino-acid biosynthesis0InformativeDirect
UniPathway (UP)peptidyl-diphthamide biosynthesis0Highly InformativeDirect

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a CSL zinc finger domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the CSL zinc finger superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]