SUPERFAMILY 1.75 HMM library and genome assignments server


Tim10-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Tim10-like [ 144121]
Superfamily:   Tim10-like [ 144122]
Families:   Tim10/DDP [ 144123] (2)


Superfamily statistics
Genomes (492) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 2,473 2,591 2
Proteins 2,472 2,590 2


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization03.741e-15Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis04.763e-14Least InformativeDirect
Biological Process (BP)single-organism cellular process3.206e-079.956e-05Least InformativeDirect
Biological Process (BP)organelle organization00Moderately InformativeDirect
Biological Process (BP)cellular localization00Moderately InformativeDirect
Biological Process (BP)organic substance transport00Moderately InformativeDirect
Biological Process (BP)macromolecule localization01.143e-13Moderately InformativeDirect
Biological Process (BP)cytoplasmic transport00InformativeDirect
Biological Process (BP)cellular membrane organization00InformativeDirect
Biological Process (BP)protein transport00InformativeDirect
Biological Process (BP)protein localization to organelle00InformativeDirect
Biological Process (BP)mitochondrion organization00InformativeDirect
Biological Process (BP)transmembrane transport00InformativeDirect
Biological Process (BP)establishment of protein localization to organelle00Highly InformativeDirect
Biological Process (BP)mitochondrial transport00Highly InformativeDirect
Biological Process (BP)protein import00Highly InformativeDirect
Biological Process (BP)protein localization to mitochondrion00Highly InformativeDirect
Biological Process (BP)mitochondrial membrane organization1.221e-110Highly InformativeDirect
Molecular Function (MF)binding0.28310.8146Least InformativeInherited
Molecular Function (MF)transporter activity2.175e-142.325e-14Moderately InformativeDirect
Molecular Function (MF)cation binding0.054510.0317Moderately InformativeInherited
Molecular Function (MF)protein transporter activity00Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle00Least InformativeDirect
Cellular Component (CC)cytoplasmic part00Least InformativeDirect
Cellular Component (CC)protein complex3.152e-121.322e-09Least InformativeDirect
Cellular Component (CC)intracellular organelle part2.938e-074.651e-06Least InformativeDirect
Cellular Component (CC)membrane0.39070.7867Least InformativeInherited
Cellular Component (CC)mitochondrial part00Moderately InformativeDirect
Cellular Component (CC)organelle envelope00Moderately InformativeDirect
Cellular Component (CC)organelle membrane0.067590.03526Moderately InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 3.741e-15 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 4.763e-14 Least Informative Direct
Biological Process (BP) single-organism cellular process 9.956e-05 Least Informative Direct
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) cellular localization 0 Moderately Informative Direct
Biological Process (BP) organic substance transport 0 Moderately Informative Direct
Biological Process (BP) macromolecule localization 1.143e-13 Moderately Informative Direct
Biological Process (BP) cytoplasmic transport 0 Informative Direct
Biological Process (BP) cellular membrane organization 0 Informative Direct
Biological Process (BP) protein transport 0 Informative Direct
Biological Process (BP) protein localization to organelle 0 Informative Direct
Biological Process (BP) mitochondrion organization 0 Informative Direct
Biological Process (BP) transmembrane transport 0 Informative Direct
Biological Process (BP) establishment of protein localization to organelle 0 Highly Informative Direct
Biological Process (BP) mitochondrial transport 0 Highly Informative Direct
Biological Process (BP) protein import 0 Highly Informative Direct
Biological Process (BP) protein localization to mitochondrion 0 Highly Informative Direct
Biological Process (BP) mitochondrial membrane organization 0 Highly Informative Direct
Molecular Function (MF) binding 0.8146 Least Informative Inherited
Molecular Function (MF) transporter activity 2.325e-14 Moderately Informative Direct
Molecular Function (MF) cation binding 0.0317 Moderately Informative Inherited
Molecular Function (MF) protein transporter activity 0 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0 Least Informative Direct
Cellular Component (CC) protein complex 1.322e-09 Least Informative Direct
Cellular Component (CC) intracellular organelle part 4.651e-06 Least Informative Direct
Cellular Component (CC) membrane 0.7867 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.03526 Moderately Informative Inherited

Document: GO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.0008788Moderately InformativeDirect
Worm Phenotype (WP)body length variant0.0001815InformativeDirect
Worm Phenotype (WP)body width variant0.0002214InformativeDirect
Worm Phenotype (WP)brood size variant0.001054InformativeInherited
Worm Phenotype (WP)small7.656e-06Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect

Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)endomesoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)gamete0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)anatomical entity in vitro0InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)whole plant0Least InformativeDirect
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)flower0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)collective phyllome structure0Least InformativeDirect
Plant ANatomical entity (PAN)root system0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant ANatomical entity (PAN)leaf0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)cardinal part of multi-tissue plant structure0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence meristem0Moderately InformativeDirect
Plant ANatomical entity (PAN)cotyledon0Moderately InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processTranslocation0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Post-translational modificationChaperone0InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Tim10-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Tim10-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]