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GAS2 domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   N domain of copper amine oxidase-like [ 55382] (5)
Superfamily:   GAS2 domain-like [ 143575]
Families:   GAS2 domain [ 143576]


Superfamily statistics
Genomes (295) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 969 1,044 1
Proteins 968 1,041 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0000000000006999 Least Informative Direct
Biological Process (BP) developmental process 0.000000000001177 Least Informative Direct
Biological Process (BP) response to stimulus 0.00000000002873 Least Informative Direct
Biological Process (BP) multicellular organismal process 0.00000000005167 Least Informative Direct
Biological Process (BP) localization 0.00009376 Least Informative Direct
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) organelle organization 0 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.000000000002999 Moderately Informative Direct
Biological Process (BP) tissue development 0.0000000004076 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.000000004181 Moderately Informative Direct
Biological Process (BP) nervous system development 0.0000003277 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0.00002847 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 0.0000401 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0.00005796 Moderately Informative Direct
Biological Process (BP) cellular localization 0.00007085 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.00008444 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.0002897 Moderately Informative Direct
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.4243 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 0.2789 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.9246 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.2708 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.7911 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.281 Moderately Informative Inherited
Biological Process (BP) cellular component movement 0 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0 Informative Direct
Biological Process (BP) tissue morphogenesis 0 Informative Direct
Biological Process (BP) regulation of organelle organization 0 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0 Informative Direct
Biological Process (BP) generation of neurons 0 Informative Direct
Biological Process (BP) regulation of anatomical structure size 0 Informative Direct
Biological Process (BP) microtubule-based process 0 Informative Direct
Biological Process (BP) cytoskeleton organization 0 Informative Direct
Biological Process (BP) regulation of growth 0.000000000000003755 Informative Direct
Biological Process (BP) protein transport 0.00000000000001953 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0.000000000001234 Informative Direct
Biological Process (BP) locomotion 0.00000000002731 Informative Direct
Biological Process (BP) actin filament-based process 0.00000000004804 Informative Direct
Biological Process (BP) cell projection organization 0.0000000008717 Informative Direct
Biological Process (BP) central nervous system development 0.000000002751 Informative Direct
Biological Process (BP) tube development 0.000000003066 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.000000007851 Informative Direct
Biological Process (BP) muscle structure development 0.00000001051 Informative Direct
Biological Process (BP) response to nutrient levels 0.0000001047 Informative Direct
Biological Process (BP) sensory organ development 0.000001317 Informative Direct
Biological Process (BP) positive regulation of cellular component organization 0.000004816 Informative Direct
Biological Process (BP) cellular component morphogenesis 0.000009527 Informative Direct
Biological Process (BP) cellular response to endogenous stimulus 0.0000154 Informative Direct
Biological Process (BP) response to hormone stimulus 0.00001737 Informative Direct
Biological Process (BP) embryonic morphogenesis 0.00009333 Informative Direct
Biological Process (BP) protein localization to organelle 0.0002259 Informative Direct
Biological Process (BP) negative regulation of gene expression 0.00042 Informative Direct
Biological Process (BP) organ morphogenesis 0.0005871 Informative Direct
Biological Process (BP) epithelium development 0.6867 Informative Inherited
Biological Process (BP) regulation of nervous system development 0.005501 Informative Inherited
Biological Process (BP) regulation of cell development 0.1841 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.007077 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.0768 Informative Inherited
Biological Process (BP) cell cycle process 0.0984 Informative Inherited
Biological Process (BP) cytoplasmic transport 0.01681 Informative Inherited
Biological Process (BP) regulation of neuron projection development 0 Highly Informative Direct
Biological Process (BP) positive regulation of growth 0 Highly Informative Direct
Biological Process (BP) regulation of microtubule polymerization or depolymerization 0 Highly Informative Direct
Biological Process (BP) regulation of cell size 0 Highly Informative Direct
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0 Highly Informative Direct
Biological Process (BP) branching morphogenesis of an epithelial tube 0 Highly Informative Direct
Biological Process (BP) muscle organ development 0 Highly Informative Direct
Biological Process (BP) neuron projection development 0 Highly Informative Direct
Biological Process (BP) negative regulation of cytoskeleton organization 0 Highly Informative Direct
Biological Process (BP) respiratory system development 0 Highly Informative Direct
Biological Process (BP) regulation of protein complex disassembly 0 Highly Informative Direct
Biological Process (BP) positive regulation of neurogenesis 0 Highly Informative Direct
Biological Process (BP) establishment or maintenance of cell polarity 0.000000000001026 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 0.00000000001216 Highly Informative Direct
Biological Process (BP) cell fate commitment 0.00000000001516 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0.00000000005213 Highly Informative Direct
Biological Process (BP) post-embryonic organ development 0.0000000003334 Highly Informative Direct
Biological Process (BP) chemotaxis 0.000000001603 Highly Informative Direct
Biological Process (BP) establishment of protein localization to organelle 0.000000005703 Highly Informative Direct
Biological Process (BP) cellular response to starvation 0.00000005086 Highly Informative Direct
Biological Process (BP) post-embryonic development 0.0000002899 Highly Informative Direct
Biological Process (BP) negative regulation of cell growth 0.000001267 Highly Informative Direct
Biological Process (BP) regulation of myeloid cell differentiation 0.000001648 Highly Informative Direct
Biological Process (BP) cytoskeleton-dependent intracellular transport 0.0000136 Highly Informative Direct
Biological Process (BP) cell part morphogenesis 0.00001706 Highly Informative Direct
Biological Process (BP) negative regulation of cell cycle 0.00008496 Highly Informative Direct
Biological Process (BP) negative regulation of cell differentiation 0.04171 Highly Informative Inherited
Biological Process (BP) microtubule-based movement 0.5606 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0 Informative Direct
Molecular Function (MF) receptor binding 0.03829 Informative Inherited
Molecular Function (MF) tubulin binding 0 Highly Informative Direct
Molecular Function (MF) transcription factor binding 0.0003215 Highly Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) protein complex 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.000001093 Least Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0000000133 Moderately Informative Direct
Cellular Component (CC) cell junction 0 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0.0000000000001305 Informative Direct
Cellular Component (CC) actin cytoskeleton 0.000000006475 Informative Direct
Cellular Component (CC) neuron projection 0.03388 Informative Inherited
Cellular Component (CC) adherens junction 0 Highly Informative Direct
Cellular Component (CC) growth cone 0.00000000000001474 Highly Informative Direct
Cellular Component (CC) spindle 0.0000000009066 Highly Informative Direct
Cellular Component (CC) intermediate filament cytoskeleton 0.00371 Highly Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentCell projection0.000000000759Moderately InformativeDirect
Cellular componentMicrotubule0.000000000000008828InformativeDirect
DomainRepeat0.0007078Least InformativeDirect
DomainSH3 domain0.000000000001232InformativeDirect
Molecular functionCalcium0.00000006446Moderately InformativeDirect
Molecular functionActin-binding2.32e-16InformativeDirect
Post-translational modificationPhosphoprotein0.000000000001345Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a GAS2 domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the GAS2 domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]