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Nqo5-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Nqo5-like [ 143242]
Superfamily:   Nqo5-like [ 143243]
Families:   Nqo5-like [ 143244]


Superfamily statistics
Genomes (2,033) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,030 16,186 1
Proteins 3,027 16,184 1


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of cellular process0.0064360.3351Least InformativeInherited
Biological Process (BP)regulation of cellular component organization0.0000007520.00007692Moderately InformativeDirect
Biological Process (BP)regulation of signal transduction0.0000023820.0002606Moderately InformativeDirect
Biological Process (BP)negative regulation of cellular process0.000039370.005036Moderately InformativeInherited
Biological Process (BP)regulation of apoptotic signaling pathway0.000000000048580.000000000199InformativeDirect
Biological Process (BP)negative regulation of signaling0.0000000039560.0000007019InformativeDirect
Biological Process (BP)negative regulation of cell communication0.0000000046240.0000007348InformativeDirect
Biological Process (BP)regulation of growth0.000000017050.0000004371InformativeDirect
Biological Process (BP)negative regulation of response to stimulus0.000000032650.000002898InformativeDirect
Biological Process (BP)regulation of intrinsic apoptotic signaling pathway0.00000000000046190.00000000000009422Highly InformativeDirect
Biological Process (BP)negative regulation of apoptotic signaling pathway0.00000000000054180.0000000000007395Highly InformativeDirect
Biological Process (BP)negative regulation of cell growth0.00000000000091310.000000000002901Highly InformativeDirect
Molecular Function (MF)oxidoreductase activity0.000014310.00000007408Moderately InformativeDirect
Molecular Function (MF)oxidoreductase activity, acting on NAD(P)H0.0000000000020060InformativeDirect
Molecular Function (MF)NADH dehydrogenase activity0.0000000000000019840Highly InformativeDirect
Cellular Component (CC)protein complex0.00025750.0002844Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.13740.5264Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.0000026760.002914Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.0000025350.005037Least InformativeInherited
Cellular Component (CC)membrane0.01440.003318Least InformativeInherited
Cellular Component (CC)mitochondrial part0.00021860.00001434Moderately InformativeDirect
Cellular Component (CC)organelle envelope0.00040530.0000141Moderately InformativeDirect
Cellular Component (CC)organelle membrane0.00097430.0005588Moderately InformativeDirect
Cellular Component (CC)mitochondrial membrane part0.00000000021730.000000001911InformativeDirect
Cellular Component (CC)respiratory chain0.0000000014870.0000000000001957InformativeDirect
Cellular Component (CC)respiratory chain complex I0.0000000000000028240Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 0.3351 Least Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.00007692 Moderately Informative Direct
Biological Process (BP) regulation of signal transduction 0.0002606 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.005036 Moderately Informative Inherited
Biological Process (BP) regulation of apoptotic signaling pathway 0.000000000199 Informative Direct
Biological Process (BP) negative regulation of signaling 0.0000007019 Informative Direct
Biological Process (BP) negative regulation of cell communication 0.0000007348 Informative Direct
Biological Process (BP) regulation of growth 0.0000004371 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.000002898 Informative Direct
Biological Process (BP) regulation of intrinsic apoptotic signaling pathway 0.00000000000009422 Highly Informative Direct
Biological Process (BP) negative regulation of apoptotic signaling pathway 0.0000000000007395 Highly Informative Direct
Biological Process (BP) negative regulation of cell growth 0.000000000002901 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity 0.00000007408 Moderately Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on NAD(P)H 0 Informative Direct
Molecular Function (MF) NADH dehydrogenase activity 0 Highly Informative Direct
Cellular Component (CC) protein complex 0.0002844 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.5264 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.002914 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.005037 Least Informative Inherited
Cellular Component (CC) membrane 0.003318 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.00001434 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.0000141 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.0005588 Moderately Informative Direct
Cellular Component (CC) mitochondrial membrane part 0.000000001911 Informative Direct
Cellular Component (CC) respiratory chain 0.0000000000001957 Informative Direct
Cellular Component (CC) respiratory chain complex I 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0Moderately InformativeDirect
Enzyme Commission (EC)With other acceptors0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processElectron transport1InformativeInherited
Biological processRespiratory chain0.0000000003396Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentPlastid0Moderately InformativeDirect
Cellular componentCell membrane0.000000000005936Moderately InformativeDirect
Cellular componentMitochondrion0.1736Moderately InformativeInherited
Cellular componentThylakoid0InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
Cellular componentMitochondrion inner membrane0.0000000003756InformativeDirect
Coding sequence diversityRNA editing0.000000006445Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionNADP0InformativeDirect
Molecular functionUbiquinone0Highly InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationQuinone0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nqo5-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Nqo5-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]