SUPERFAMILY 1.75 HMM library and genome assignments server


WGR domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   WGR domain-like [ 142920]
Superfamily:   WGR domain-like [ 142921]
Families:   WGR domain [ 142922]


Superfamily statistics
Genomes (600) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,284 0 1
Proteins 1,271 0 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular macromolecule metabolic process 0 Least Informative Direct
Biological Process (BP) response to stimulus 4.12e-11 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 9.31e-11 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 1.544e-10 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 5.385e-10 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 5.723e-10 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0005974 Least Informative Direct
Biological Process (BP) biosynthetic process 0.97 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.02575 Least Informative Inherited
Biological Process (BP) cellular response to stress 0 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.0005658 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.06646 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.1349 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.02363 Moderately Informative Inherited
Biological Process (BP) homeostatic process 0.002492 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.4294 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.003355 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.02887 Moderately Informative Inherited
Biological Process (BP) DNA metabolic process 0 Informative Direct
Biological Process (BP) chromosome organization 1.48e-10 Informative Direct
Biological Process (BP) response to DNA damage stimulus 1.237e-09 Informative Direct
Biological Process (BP) regulation of growth 2.955e-06 Informative Direct
Biological Process (BP) response to inorganic substance 6.724e-05 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.0004177 Informative Direct
Biological Process (BP) response to oxidative stress 0.001811 Informative Inherited
Biological Process (BP) response to superoxide 0 Highly Informative Direct
Biological Process (BP) protein glycosylation 2.657e-11 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 4.285e-07 Highly Informative Direct
Biological Process (BP) double-strand break repair 2.124e-06 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 4.615e-08 Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 1.992e-12 Highly Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 2.152e-07 Least Informative Direct
Cellular Component (CC) intracellular organelle part 4.332e-05 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0.03762 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.03857 Moderately Informative Inherited
Cellular Component (CC) chromosome 0.01935 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)abnormal metabolism0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal response to radiation0InformativeDirect
Mammalian Phenotype (MP)abnormal sensitivity to induced morbidity/mortality0InformativeDirect
Mammalian Phenotype (MP)increased mortality induced by ionizing radiation0Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Moderately InformativeDirect
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect

Document: WP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Pentosyltransferases0InformativeDirect
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage1.084e-07Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainRepeat1.628e-09Least InformativeDirect
DomainZinc-finger1.289e-10Moderately InformativeDirect
Molecular functionZinc1.016e-06Least InformativeDirect
Molecular functionDNA-binding0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect
Post-translational modificationADP-ribosylation0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a WGR domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the WGR domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]