SUPERFAMILY 1.75 HMM library and genome assignments server

WGR domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   WGR domain-like [ 142920]
Superfamily:   WGR domain-like [ 142921]
Families:   WGR domain [ 142922]


Superfamily statistics
Genomes (611) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,322 5,063 1
Proteins 1,308 5,051 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular macromolecule metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.00000000001678 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.00000000009358 Least Informative Direct
Biological Process (BP) response to stimulus 0.0000000001177 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.0000000001546 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.0000000005704 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.000000000571 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0004621 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.04023 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.9606 Least Informative Inherited
Biological Process (BP) cellular response to stress 0 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0.0004763 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.0006105 Moderately Informative Direct
Biological Process (BP) cellular response to chemical stimulus 0.1417 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.07734 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.02293 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 0.4197 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.004013 Moderately Informative Inherited
Biological Process (BP) single-organism organelle organization 0.001214 Moderately Informative Inherited
Biological Process (BP) DNA repair 0 Informative Direct
Biological Process (BP) anatomical structure homeostasis 0.0000000000009912 Informative Direct
Biological Process (BP) chromosome organization 0.0000000002185 Informative Direct
Biological Process (BP) regulation of growth 0.00000256 Informative Direct
Biological Process (BP) response to inorganic substance 0.00006909 Informative Direct
Biological Process (BP) cellular response to oxygen-containing compound 0.0004355 Informative Direct
Biological Process (BP) response to oxidative stress 0.002279 Informative Inherited
Biological Process (BP) response to superoxide 0 Highly Informative Direct
Biological Process (BP) protein glycosylation 0.00000000678 Highly Informative Direct
Biological Process (BP) cellular response to reactive oxygen species 0.0000004922 Highly Informative Direct
Biological Process (BP) double-strand break repair 0.00000261 Highly Informative Direct
Molecular Function (MF) transferase activity 0.04479 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.00000006623 Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.000000000002948 Highly Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.0000002422 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.00003118 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) nuclear part 0.01701 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.01634 Moderately Informative Inherited
Cellular Component (CC) chromosome 0.01641 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)abnormal metabolism0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal response to radiation0InformativeDirect
Mammalian Phenotype (MP)abnormal sensitivity to induced morbidity/mortality0InformativeDirect
Mammalian Phenotype (MP)increased mortality induced by ionizing radiation0Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Moderately InformativeDirect
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect

Document: WP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Pentosyltransferases0InformativeDirect
Enzyme Commission (EC)NAD(+) ADP-ribosyltransferase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage0.0000001076Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect
DomainRepeat0.000000001642Least InformativeDirect
DomainZinc-finger0.0000000001239Moderately InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect
Molecular functionZinc0.000001068Least InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationGlycosyltransferase0InformativeDirect
Post-translational modificationADP-ribosylation0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a WGR domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the WGR domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]