SUPERFAMILY 1.75 HMM library and genome assignments server


TFB5-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   TFB5-like [ 142896]
Superfamily:   TFB5-like [ 142897]
Families:   TFB5-like [ 142898]


Superfamily statistics
Genomes (392) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 480 490 1
Proteins 480 490 1


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)heterocycle metabolic process6.099e-050.0001525Least InformativeDirect
Biological Process (BP)cellular aromatic compound metabolic process6.3e-050.0001683Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.00011410.0002566Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.00027180.0004523Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0044370.03763Least InformativeInherited
Biological Process (BP)response to stimulus0.0014220.007077Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.00013980.001103Least InformativeInherited
Biological Process (BP)cellular response to stress3.179e-071.745e-06Moderately InformativeDirect
Biological Process (BP)response to DNA damage stimulus1.981e-091.95e-08InformativeDirect
Biological Process (BP)DNA metabolic process3.147e-091.049e-07InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) heterocycle metabolic process 0.0001525 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.0001683 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0002566 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.0004523 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.03763 Least Informative Inherited
Biological Process (BP) response to stimulus 0.007077 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.001103 Least Informative Inherited
Biological Process (BP) cellular response to stress 1.745e-06 Moderately Informative Direct
Biological Process (BP) response to DNA damage stimulus 1.95e-08 Informative Direct
Biological Process (BP) DNA metabolic process 1.049e-07 Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage0Moderately InformativeDirect
Biological processTranscription regulation0Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a TFB5-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the TFB5-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]