SUPERFAMILY 1.75 HMM library and genome assignments server


TFB5-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   TFB5-like [ 142896]
Superfamily:   TFB5-like [ 142897]
Families:   TFB5-like [ 142898]


Superfamily statistics
Genomes (360) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 432 333 1
Proteins 432 333 1


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process6.303e-050.0001751Least InformativeDirect
Biological Process (BP)nitrogen compound metabolic process0.00026740.0004645Least InformativeDirect
Biological Process (BP)heterocycle metabolic process6.003e-050.000158Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.00011230.0002661Least InformativeDirect
Biological Process (BP)single-organism cellular process0.0043430.03707Least InformativeInherited
Biological Process (BP)response to stimulus0.001370.006965Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process0.00014310.001136Least InformativeInherited
Biological Process (BP)cellular response to stress3.239e-071.752e-06Moderately InformativeDirect
Biological Process (BP)DNA metabolic process3.742e-091.138e-07InformativeDirect
Biological Process (BP)response to DNA damage stimulus2.282e-092.064e-08InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.0042870.01727Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0.0001751 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.0004645 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.000158 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0002661 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.03707 Least Informative Inherited
Biological Process (BP) response to stimulus 0.006965 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 0.001136 Least Informative Inherited
Biological Process (BP) cellular response to stress 1.752e-06 Moderately Informative Direct
Biological Process (BP) DNA metabolic process 1.138e-07 Informative Direct
Biological Process (BP) response to DNA damage stimulus 2.064e-08 Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.01727 Least Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA damage0Moderately InformativeDirect
Biological processTranscription regulation0Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a TFB5-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the TFB5-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]