SUPERFAMILY 1.75 HMM library and genome assignments server


Nqo1 FMN-binding domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Nqo1 FMN-binding domain-like [ 142018]
Superfamily:   Nqo1 FMN-binding domain-like [ 142019]
Families:   Nqo1 FMN-binding domain-like [ 142020]


Superfamily statistics
Genomes (2,088) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,651 17,701 1
Proteins 3,645 17,688 1


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Cellular Component (CC)membrane00.0003513Least InformativeDirect
Cellular Component (CC)cytoplasmic part00.01669Least InformativeInherited
Cellular Component (CC)intracellular organelle part00.03208Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle00.01631Least InformativeInherited
Cellular Component (CC)mitochondrial part02.153e-11Moderately InformativeDirect
Cellular Component (CC)organelle envelope06.367e-11Moderately InformativeDirect
Cellular Component (CC)organelle membrane02.175e-08Moderately InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.01705 Least Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.002305 Informative Inherited
Molecular Function (MF) oxidoreductase activity 2.745e-10 Moderately Informative Direct
Cellular Component (CC) membrane 0.0003513 Least Informative Direct
Cellular Component (CC) protein complex 1.736e-05 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.01669 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.03208 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.01631 Least Informative Inherited
Cellular Component (CC) mitochondrial part 2.153e-11 Moderately Informative Direct
Cellular Component (CC) organelle envelope 6.367e-11 Moderately Informative Direct
Cellular Component (CC) organelle membrane 2.175e-08 Moderately Informative Direct
Cellular Component (CC) respiratory chain 1.586e-10 Informative Direct
Cellular Component (CC) respiratory chain complex I 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0Moderately InformativeDirect
Enzyme Commission (EC)With other acceptors0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0Highly InformativeDirect
Enzyme Commission (EC)NADH dehydrogenase6.051e-06Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processElectron transport0InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane6.045e-10Moderately InformativeDirect
Cellular componentMitochondrion0.0001087Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
Cellular componentMitochondrion inner membrane4.32e-05InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular functionFMN0InformativeDirect
Molecular function4Fe-4S0InformativeDirect
Molecular functionUbiquinone0Highly InformativeDirect
Post-translational modificationOxidoreductase2.237e-16Moderately InformativeDirect
Post-translational modificationQuinone0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nqo1 FMN-binding domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Nqo1 FMN-binding domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]