SUPERFAMILY 1.75 HMM library and genome assignments server


Nqo1 FMN-binding domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Nqo1 FMN-binding domain-like [ 142018]
Superfamily:   Nqo1 FMN-binding domain-like [ 142019]
Families:   Nqo1 FMN-binding domain-like [ 142020]


Superfamily statistics
Genomes (2,081) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,635 17,701 1
Proteins 3,630 17,688 1


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Cellular Component (CC)membrane00.0001458Least InformativeDirect
Cellular Component (CC)cytoplasmic part00.01028Least InformativeInherited
Cellular Component (CC)intracellular organelle part00.01914Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle00.004519Least InformativeInherited
Cellular Component (CC)mitochondrial part00.000000000001775Moderately InformativeDirect
Cellular Component (CC)organelle envelope00.000000000005668Moderately InformativeDirect
Cellular Component (CC)organelle membrane00.000000000999Moderately InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.01641 Least Informative Inherited
Biological Process (BP) oxidation-reduction process 0.000000005159 Moderately Informative Direct
Biological Process (BP) energy derivation by oxidation of organic compounds 0.002319 Informative Inherited
Molecular Function (MF) oxidoreductase activity 0.000000000008894 Moderately Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on NAD(P)H 0.000209 Highly Informative Direct
Cellular Component (CC) membrane 0.0001458 Least Informative Direct
Cellular Component (CC) protein complex 0.000001842 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.01028 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.01914 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.004519 Least Informative Inherited
Cellular Component (CC) mitochondrial part 0.000000000001775 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.000000000005668 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.000000000999 Moderately Informative Direct
Cellular Component (CC) respiratory chain 0.000000000001728 Informative Direct
Cellular Component (CC) mitochondrial membrane part 0.00003027 Informative Direct
Cellular Component (CC) respiratory chain complex I 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0Moderately InformativeDirect
Enzyme Commission (EC)With other acceptors0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0Highly InformativeDirect
Enzyme Commission (EC)NADH dehydrogenase0.000006101Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processElectron transport0InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0.0000000005374Moderately InformativeDirect
Cellular componentMitochondrion0.0001098Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
Cellular componentMitochondrion inner membrane0.00004326InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular function4Fe-4S0InformativeDirect
Molecular functionFMN0InformativeDirect
Molecular functionIron-sulfur0InformativeDirect
Molecular functionUbiquinone0Highly InformativeDirect
Post-translational modificationOxidoreductase2.234e-16Moderately InformativeDirect
Post-translational modificationQuinone0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nqo1 FMN-binding domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Nqo1 FMN-binding domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]