SUPERFAMILY 1.75 HMM library and genome assignments server

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PTPA-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   PTPA-like [ 140983]
Superfamily:   PTPA-like [ 140984]
Families:   PTPA-like [ 140985]


Superfamily statistics
Genomes (486) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 882 1,071 6
Proteins 868 1,056 6


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of metabolic process0.080350.07124Least InformativeInherited
Biological Process (BP)regulation of catalytic activity0.000048040.0000009398Moderately InformativeDirect
Molecular Function (MF)binding0.046180.3735Least InformativeInherited
Molecular Function (MF)enzyme regulator activity0.0000053910.000000002486Moderately InformativeDirect
Molecular Function (MF)enzyme binding0.00000040240.000002051InformativeDirect
Molecular Function (MF)protein phosphatase binding0.000000000043240.000000000002665Highly InformativeDirect
Molecular Function (MF)phosphatase regulator activity0.00000000013790Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.07124 Least Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.0000009398 Moderately Informative Direct
Molecular Function (MF) binding 0.3735 Least Informative Inherited
Molecular Function (MF) enzyme regulator activity 0.000000002486 Moderately Informative Direct
Molecular Function (MF) enzyme binding 0.000002051 Informative Direct
Molecular Function (MF) protein phosphatase binding 0.000000000002665 Highly Informative Direct
Molecular Function (MF) phosphatase regulator activity 0 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.1657 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.1546 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.002007 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.01131 Moderately Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Peptidylprolyl isomerase0InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Peptidylprolyl isomerase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentNucleus0.000000001792Least InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationRotamase0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a PTPA-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the PTPA-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]