SUPERFAMILY 1.75 HMM library and genome assignments server


EB1 dimerisation domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   EB1 dimerisation domain-like [ 140611]
Superfamily:   EB1 dimerisation domain-like [ 140612]
Families:   EB1 dimerisation domain-like [ 140613]


Superfamily statistics
Genomes (480) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 925 995 5
Proteins 923 994 5


Functional annotation
General category coiled coil
Detailed category This is a complex coiled arrangement. The details of which will appear on this page shortly (some coiled coil details are being checked before they are included on the site). If you want to see examples of the states please click here here. If you require further details urgently please contact Owen Rackham

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 1.036e-06 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.001481 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.005907 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.0976 Least Informative Inherited
Biological Process (BP) cellular localization 1.623e-09 Moderately Informative Direct
Biological Process (BP) macromolecule localization 9.543e-08 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 1.415e-07 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.0002419 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.0007777 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0211 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.06509 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 5.618e-15 Informative Direct
Biological Process (BP) protein localization to organelle 2.709e-13 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 1.034e-11 Informative Direct
Biological Process (BP) regulation of organelle organization 2.773e-11 Informative Direct
Biological Process (BP) cytoskeleton organization 4.952e-06 Informative Direct
Biological Process (BP) organelle assembly 2.209e-05 Informative Direct
Biological Process (BP) cell cycle process 2.301e-05 Informative Direct
Biological Process (BP) microtubule-based process 3.809e-05 Informative Direct
Biological Process (BP) organelle localization 0.08461 Informative Inherited
Biological Process (BP) protein complex assembly 0.05252 Informative Inherited
Biological Process (BP) regulation of microtubule polymerization or depolymerization 0 Highly Informative Direct
Biological Process (BP) negative regulation of cytoskeleton organization 0 Highly Informative Direct
Biological Process (BP) regulation of protein complex assembly 8.595e-10 Highly Informative Direct
Biological Process (BP) chromosome segregation 3.222e-06 Highly Informative Direct
Biological Process (BP) spindle organization 1.277e-05 Highly Informative Direct
Molecular Function (MF) binding 4.579e-08 Least Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0 Informative Direct
Molecular Function (MF) tubulin binding 0 Highly Informative Direct
Cellular Component (CC) protein complex 0 Least Informative Direct
Cellular Component (CC) intracellular non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1.118e-11 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.03965 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0 Moderately Informative Direct
Cellular Component (CC) cell cortex 0 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0 Informative Direct
Cellular Component (CC) spindle 0 Highly Informative Direct
Cellular Component (CC) cortical cytoskeleton 5.241e-06 Highly Informative Direct

Document: GO annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell cycle0Moderately InformativeDirect
Biological processMitosis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentMicrotubule0InformativeDirect
Post-translational modificationPhosphoprotein9.613e-08Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a EB1 dimerisation domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the EB1 dimerisation domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]