SUPERFAMILY 1.75 HMM library and genome assignments server

EB1 dimerisation domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   EB1 dimerisation domain-like [ 140611]
Superfamily:   EB1 dimerisation domain-like [ 140612]
Families:   EB1 dimerisation domain-like [ 140613]


Superfamily statistics
Genomes (481) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 927 995 5
Proteins 925 994 5


Functional annotation
General category coiled coil
Detailed category This is a complex coiled arrangement. The details of which will appear on this page shortly (some coiled coil details are being checked before they are included on the site). If you want to see examples of the states please click here here. If you require further details urgently please contact Owen Rackham

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 0.000001058 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.005475 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.1093 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.6869 Least Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.0000002367 Moderately Informative Direct
Biological Process (BP) cellular localization 0.000004394 Moderately Informative Direct
Biological Process (BP) macromolecule localization 0.0002168 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.000231 Moderately Informative Direct
Biological Process (BP) single-organism organelle organization 0.0004037 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 0.0007169 Moderately Informative Direct
Biological Process (BP) negative regulation of cellular process 0.001096 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.001803 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular component organization 0.00000000000001071 Informative Direct
Biological Process (BP) protein localization to organelle 0.0000000000002345 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0.00000000001769 Informative Direct
Biological Process (BP) regulation of organelle organization 0.00000000006841 Informative Direct
Biological Process (BP) mitotic cell cycle 0.0000000008981 Informative Direct
Biological Process (BP) cell cycle process 0.0000004116 Informative Direct
Biological Process (BP) microtubule-based process 0.000001068 Informative Direct
Biological Process (BP) cytoskeleton organization 0.000004215 Informative Direct
Biological Process (BP) organelle assembly 0.00002319 Informative Direct
Biological Process (BP) organelle localization 0.08694 Informative Inherited
Biological Process (BP) negative regulation of cytoskeleton organization 0 Highly Informative Direct
Biological Process (BP) regulation of microtubule polymerization or depolymerization 0 Highly Informative Direct
Biological Process (BP) regulation of protein complex assembly 0.0000000006655 Highly Informative Direct
Biological Process (BP) chromosome segregation 0.0000001277 Highly Informative Direct
Biological Process (BP) spindle organization 0.000009369 Highly Informative Direct
Molecular Function (MF) binding 0.00000003002 Least Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0 Informative Direct
Molecular Function (MF) protein complex binding 0 Informative Direct
Molecular Function (MF) tubulin binding 0 Highly Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) protein complex 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.000000000007423 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0456 Least Informative Inherited
Cellular Component (CC) cytoskeleton 0 Moderately Informative Direct
Cellular Component (CC) cell cortex 0 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0 Informative Direct
Cellular Component (CC) spindle 0 Highly Informative Direct
Cellular Component (CC) cortical cytoskeleton 0.000004073 Highly Informative Direct

Document: GO annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell cycle0Moderately InformativeDirect
Biological processMitosis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentMicrotubule0InformativeDirect
Post-translational modificationPhosphoprotein0.0000000983Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a EB1 dimerisation domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the EB1 dimerisation domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]