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WRKY DNA-binding domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   WRKY DNA-binding domain [ 118289]
Superfamily:   WRKY DNA-binding domain [ 118290]
Families:   WRKY DNA-binding domain [ 118291]


Superfamily statistics
Genomes (79) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 6,919 5,572 1
Proteins 5,880 4,767 1


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0.000000000000348 Least Informative Direct
Biological Process (BP) localization 0.0002394 Least Informative Direct
Biological Process (BP) biosynthetic process 0.01312 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.001041 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.3676 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.4204 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.1538 Least Informative Inherited
Biological Process (BP) regulation of cellular process 0.6247 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.01361 Least Informative Inherited
Biological Process (BP) multi-organism process 0.00000000000003126 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.000000000005619 Moderately Informative Direct
Biological Process (BP) response to endogenous stimulus 0.0000000005706 Moderately Informative Direct
Biological Process (BP) immune system process 0.000000004739 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 0.000001793 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.0003198 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0.0004234 Moderately Informative Direct
Biological Process (BP) signal transduction 0.0006561 Moderately Informative Direct
Biological Process (BP) single-organism biosynthetic process 0.001056 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.1539 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.004684 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.001152 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.001533 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.003516 Moderately Informative Inherited
Biological Process (BP) ion transport 0.06721 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.01184 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.07559 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.2232 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.3045 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.00146 Moderately Informative Inherited
Biological Process (BP) regulation of defense response 0.000000001528 Informative Direct
Biological Process (BP) organic hydroxy compound biosynthetic process 0.000000008232 Informative Direct
Biological Process (BP) monocarboxylic acid biosynthetic process 0.00000003835 Informative Direct
Biological Process (BP) anion transport 0.00000006988 Informative Direct
Biological Process (BP) defense response 0.0000000828 Informative Direct
Biological Process (BP) nitrogen compound transport 0.0001508 Informative Direct
Biological Process (BP) negative regulation of response to stimulus 0.0001575 Informative Direct
Biological Process (BP) regulation of immune response 0.0003103 Informative Direct
Biological Process (BP) immune response 0.0004191 Informative Direct
Biological Process (BP) intracellular signal transduction 0.0005477 Informative Direct
Biological Process (BP) cellular response to endogenous stimulus 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.03492 Informative Inherited
Biological Process (BP) response to bacterium 0.01553 Informative Inherited
Biological Process (BP) response to nutrient levels 0.001522 Informative Inherited
Biological Process (BP) response to organonitrogen compound 0.001853 Informative Inherited
Biological Process (BP) response to hormone stimulus 0.04084 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.01271 Informative Inherited
Biological Process (BP) protein transport 0.259 Informative Inherited
Biological Process (BP) immune effector process 0.003699 Informative Inherited
Biological Process (BP) benzene-containing compound metabolic process 0.00000000002355 Highly Informative Direct
Biological Process (BP) hormone-mediated signaling pathway 0.000000006253 Highly Informative Direct
Biological Process (BP) regulation of reactive oxygen species metabolic process 0.00000001057 Highly Informative Direct
Biological Process (BP) regulation of multi-organism process 0.00000003236 Highly Informative Direct
Biological Process (BP) MAPK cascade 0.00000005388 Highly Informative Direct
Biological Process (BP) membrane fusion 0.000001992 Highly Informative Direct
Biological Process (BP) regulation of cellular response to stress 0.00001441 Highly Informative Direct
Biological Process (BP) defense response to bacterium 0.00001943 Highly Informative Direct
Biological Process (BP) response to fungus 0.0002451 Highly Informative Direct
Biological Process (BP) regulation of innate immune response 0.002122 Highly Informative Inherited
Biological Process (BP) innate immune response 0.2816 Highly Informative Inherited
Molecular Function (MF) binding 0.4663 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.01147 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 0 Informative Direct
Molecular Function (MF) DNA binding 0.0007726 Informative Direct
Molecular Function (MF) sequence-specific DNA binding transcription factor activity 0 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.01143 Least Informative Inherited

Document: GO annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Biological processPlant defense0.00000008356InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Coding sequence diversityAlternative splicing0.00000001084Least InformativeDirect
DomainRepeat0.0002558Least InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a WRKY DNA-binding domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the WRKY DNA-binding domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]