SUPERFAMILY 1.75 HMM library and genome assignments server

GTF2I-like repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   GTF2I-like repeat [ 117772]
Superfamily:   GTF2I-like repeat [ 117773]
Families:   GTF2I-like repeat [ 117774]


Superfamily statistics
Genomes (68) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 947 1,136 1
Proteins 237 282 1


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.9285 Least Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.00000001297 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0.000006086 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.00001007 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.00001769 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.00003011 Moderately Informative Direct
Biological Process (BP) regulation of system process 0.0000000000000567 Informative Direct
Biological Process (BP) regulation of muscle system process 0 Highly Informative Direct
Molecular Function (MF) binding 0.2839 Least Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 0.0000000002003 Informative Direct
Molecular Function (MF) enzyme binding 0.00000003882 Informative Direct
Molecular Function (MF) kinase binding 0.0000000000001248 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0000000008351 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.8451 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) cell projection 0.00009295 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.004995 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.804 Moderately Informative Inherited
Cellular Component (CC) cell body 0.000000001298 Highly Informative Direct

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)syndrome0Moderately InformativeDirect

Document: DO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Coding sequence diversityAlternative splicing0.00000003828Least InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect
Post-translational modificationPhosphoprotein0.000008011Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a GTF2I-like repeat domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the GTF2I-like repeat superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · UniProtKB KeyWords (KW) · Internal database links ]