SUPERFAMILY 1.75 HMM library and genome assignments server

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GTF2I-like repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   GTF2I-like repeat [ 117772]
Superfamily:   GTF2I-like repeat [ 117773]
Families:   GTF2I-like repeat [ 117774]


Superfamily statistics
Genomes (68) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 947 1,136 1
Proteins 237 282 1


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of metabolic process 0.876 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.00000003164 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 0.000005568 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.000009261 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.00001522 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.00001593 Moderately Informative Direct
Biological Process (BP) regulation of system process 0.00000000005398 Informative Direct
Molecular Function (MF) binding 0.2713 Least Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 0.0000000001885 Informative Direct
Molecular Function (MF) enzyme binding 0.00000003617 Informative Direct
Molecular Function (MF) kinase binding 0.0000000000001096 Highly Informative Direct
Molecular Function (MF) sequence-specific DNA binding transcription factor activity 0.000000000009227 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.00000000009116 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 0.8961 Least Informative Inherited
Cellular Component (CC) cell projection 0.0000728 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.001527 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.7644 Moderately Informative Inherited
Cellular Component (CC) cell body 0.000000001315 Highly Informative Direct

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)syndrome0Moderately InformativeDirect

Document: DO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Coding sequence diversityAlternative splicing0.00000003088Least InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionDNA-binding0Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.00000789Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a GTF2I-like repeat domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the GTF2I-like repeat superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · UniProtKB KeyWords (KW) · Internal database links ]