SUPERFAMILY 1.75 HMM library and genome assignments server


GTF2I-like repeat superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   GTF2I-like repeat [ 117772]
Superfamily:   GTF2I-like repeat [ 117773]
Families:   GTF2I-like repeat [ 117774]


Superfamily statistics
Genomes (63) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 901 893 1
Proteins 229 226 1


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) developmental process 2.512e-06 Least Informative Direct
Biological Process (BP) multicellular organismal process 1.035e-05 Least Informative Direct
Biological Process (BP) regulation of metabolic process 0.888 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 2.829e-08 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 1.504e-06 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 2.534e-06 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 4.051e-06 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 4.127e-06 Moderately Informative Direct
Biological Process (BP) single-organism developmental process 6.588e-06 Moderately Informative Direct
Biological Process (BP) regulation of system process 5.066e-11 Informative Direct
Molecular Function (MF) binding 0.2446 Least Informative Inherited
Molecular Function (MF) nucleic acid binding transcription factor activity 2.35e-10 Informative Direct
Molecular Function (MF) enzyme binding 2.298e-08 Informative Direct
Molecular Function (MF) sequence-specific DNA binding transcription factor activity 2.205e-12 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1.824e-09 Least Informative Direct
Cellular Component (CC) cell projection 1.972e-05 Moderately Informative Direct
Cellular Component (CC) cell body 3.332e-10 Highly Informative Direct

Document: GO annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)syndrome0Moderately InformativeDirect

Document: DO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0Moderately InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Coding sequence diversityAlternative splicing2.746e-08Least InformativeDirect
DomainRepeat0Least InformativeDirect
Molecular functionDNA-binding0Least InformativeDirect
Post-translational modificationPhosphoprotein7.736e-06Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a GTF2I-like repeat domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the GTF2I-like repeat superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Disease Ontology (DO) · UniProtKB KeyWords (KW) · Internal database links ]