SUPERFAMILY 1.75 HMM library and genome assignments server


Mitochondrial ATP synthase coupling factor 6 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Mitochondrial ATP synthase coupling factor 6 [ 111356]
Superfamily:   Mitochondrial ATP synthase coupling factor 6 [ 111357]
Families:   Mitochondrial ATP synthase coupling factor 6 [ 111358]


Superfamily statistics
Genomes (131) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 194 218 2
Proteins 194 218 2


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Cellular Component (CC)membrane0.0001130.000342Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle00Least InformativeDirect
Cellular Component (CC)protein complex2.082e-061.682e-05Least InformativeDirect
Cellular Component (CC)cytoplasmic part00Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.0086310.02226Least InformativeInherited
Cellular Component (CC)organelle membrane5.25e-069.409e-07Moderately InformativeDirect
Cellular Component (CC)organelle envelope1.515e-068.795e-08Moderately InformativeDirect
Cellular Component (CC)mitochondrial part6.225e-074.049e-08Moderately InformativeDirect
Cellular Component (CC)mitochondrial membrane part1.173e-071.911e-09InformativeDirect
Cellular Component (CC)mitochondrial proton-transporting ATP synthase complex5.524e-068.575e-07Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Cellular Component (CC) membrane 0.000342 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) protein complex 1.682e-05 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.02226 Least Informative Inherited
Cellular Component (CC) organelle membrane 9.409e-07 Moderately Informative Direct
Cellular Component (CC) organelle envelope 8.795e-08 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 4.049e-08 Moderately Informative Direct
Cellular Component (CC) mitochondrial membrane part 1.911e-09 Informative Direct
Cellular Component (CC) mitochondrial proton-transporting ATP synthase complex 8.575e-07 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processIon transport0Moderately InformativeDirect
Biological processHydrogen ion transport0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0InformativeDirect
DomainTransit peptide4.207e-14Moderately InformativeDirect
Post-translational modificationAcetylation7.439e-12Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR008387 SSF111357 Protein matches
Abstract

This entry represents subunit F6 (or coupling factor 6) found in the F0 complex of F-ATPases in mitochondria. The F6 subunit is part of the peripheral stalk that links the F1 and F0 complexes together, and which acts as a stator to prevent certain subunits from rotating with the central rotary element. The peripheral stalk differs in subunit composition between mitochondrial, chloroplast and bacterial F-ATPases. In mitochondria, the peripheral stalk is composed of one copy each of subunits OSCP (oligomycin sensitivity conferral protein), F6, B and D [PubMed16045926]. There is no homologue of subunit F6 in bacterial or chloroplast F-ATPase, whose peripheral stalks are composed of one copy of the delta subunit (homologous to OSCP), and two copies of subunit B in bacteria, or one copy each of subunits B and Bż in chloroplasts and photosynthetic bacteria.

More information about this protein can be found at Protein of the Month: ATP Synthases.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Mitochondrial ATP synthase coupling factor 6 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Mitochondrial ATP synthase coupling factor 6 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]