SUPERFAMILY 1.75 HMM library and genome assignments server

Gamma-glutamyl cyclotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Gamma-glutamyl cyclotransferase-like [ 110856]
Superfamily:   Gamma-glutamyl cyclotransferase-like [ 110857]
Families:   Gamma-glutamyl cyclotransferase-like [ 110858] (3)


Superfamily statistics
Genomes (1,596) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,679 12,808 3
Proteins 3,601 12,692 3


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)regulation of cellular process0.53721Least InformativeInherited
Biological Process (BP)response to stimulus0.69341Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.0065190.3422Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.0085970.363Least InformativeInherited
Biological Process (BP)single-organism cellular process0.0330.9861Least InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.00000006020.000001256Moderately InformativeDirect
Biological Process (BP)single-organism catabolic process0.00029870.0002234Moderately InformativeDirect
Biological Process (BP)signal transduction0.030560.4657Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.00038770.001863Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.00043290.004852Moderately InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00032880.00002002InformativeDirect
Biological Process (BP)carboxylic acid catabolic process0.00010110.00004323InformativeDirect
Biological Process (BP)organonitrogen compound catabolic process0.0000082320.00002121InformativeDirect
Biological Process (BP)apoptotic process0.00079110.001073InformativeInherited
Molecular Function (MF)transferase activity0.000042380.01499Least InformativeInherited
Molecular Function (MF)transferase activity, transferring acyl groups0.000000000000033370.000000000002731InformativeDirect
Molecular Function (MF)transferase activity, transferring amino-acyl groups00Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.3422 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 0.363 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.9861 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.000001256 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.0002234 Moderately Informative Direct
Biological Process (BP) signal transduction 0.4657 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.001863 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.004852 Moderately Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.00002002 Informative Direct
Biological Process (BP) carboxylic acid catabolic process 0.00004323 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0.00002121 Informative Direct
Biological Process (BP) apoptotic process 0.001073 Informative Inherited
Molecular Function (MF) transferase activity 0.01499 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.000000000002731 Informative Direct
Molecular Function (MF) transferase activity, transferring amino-acyl groups 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Aminoacyltransferases0InformativeDirect

Document: EC annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Post-translational modificationTransferase0.000000001778Least InformativeDirect
Post-translational modificationAcyltransferase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Gamma-glutamyl cyclotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the Gamma-glutamyl cyclotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]