SUPERFAMILY 1.75 HMM library and genome assignments server


Surp module (SWAP domain) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Surp module (SWAP domain) [ 109904]
Superfamily:   Surp module (SWAP domain) [ 109905]
Families:   Surp module (SWAP domain) [ 109906] (3)


Superfamily statistics
Genomes (505) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,253 3,128 5
Proteins 2,237 2,176 5


Functional annotation
General category Regulation
Detailed category RNA binding, metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) heterocycle metabolic process 1.217e-05 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 1.492e-05 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 3.573e-05 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.0001125 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0006436 Least Informative Direct
Biological Process (BP) RNA metabolic process 3.559e-10 Moderately Informative Direct
Biological Process (BP) gene expression 1.358e-09 Moderately Informative Direct
Biological Process (BP) RNA processing 3.117e-14 Informative Direct
Biological Process (BP) RNA splicing 0.0002732 Highly Informative Direct
Biological Process (BP) mRNA processing 0.007825 Highly Informative Inherited
Molecular Function (MF) binding 0.03717 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 8.471e-07 Moderately Informative Direct
Molecular Function (MF) RNA binding 1.087e-11 Informative Direct
Cellular Component (CC) intracellular organelle part 0.0161 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.1734 Least Informative Inherited
Cellular Component (CC) ribonucleoprotein complex 1.66e-06 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.005799 Moderately Informative Inherited
Cellular Component (CC) spliceosomal complex 1.518e-08 Highly Informative Direct

Document: GO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)alimentary system0Least InformativeDirect
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)central nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)cell0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)portion of tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)intestine0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)surface structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)endomesoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)gamete0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)visual system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)skin0InformativeDirect
Xenopus ANatomical entity (XAN)liver and biliary system0InformativeDirect
Xenopus ANatomical entity (XAN)anatomical entity in vitro0InformativeDirect
Xenopus ANatomical entity (XAN)solid compound organ0InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)flower0Least InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTranscription regulation0.0009779Moderately InformativeDirect
Biological processmRNA splicing0InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentSpliceosome0InformativeDirect
DomainRepeat1.402e-07Least InformativeDirect
Molecular functionRNA-binding0.0002994Moderately InformativeDirect
Post-translational modificationPhosphoprotein3.786e-08Least InformativeDirect
Post-translational modificationAcetylation9.104e-07Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Surp module (SWAP domain) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Surp module (SWAP domain) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]