SUPERFAMILY 1.75 HMM library and genome assignments server


Sema domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   Sema domain [ 101912]
Families:   Sema domain [ 101913] (3)


Superfamily statistics
Genomes (141) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,599 3,801 3
Proteins 3,457 3,756 3


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)multicellular organismal process2.646e-060Least InformativeDirect
Biological Process (BP)developmental process8.657e-070Least InformativeDirect
Biological Process (BP)single-organism cellular process4.995e-065.618e-15Least InformativeDirect
Biological Process (BP)regulation of cellular process0.00022780Least InformativeDirect
Biological Process (BP)response to stimulus0.00085950Least InformativeDirect
Biological Process (BP)cellular component organization or biogenesis0.007380Least InformativeInherited
Biological Process (BP)localization0.0013150.001034Least InformativeInherited
Biological Process (BP)cell differentiation5.929e-090Moderately InformativeDirect
Biological Process (BP)regulation of developmental process0.00029659.759e-09Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.061415.681e-13Moderately InformativeInherited
Biological Process (BP)tissue development0.0014910.3695Moderately InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.001020Moderately InformativeInherited
Biological Process (BP)nervous system development0.0090670Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.0048766.463e-09Moderately InformativeInherited
Biological Process (BP)signal transduction0.055290Moderately InformativeInherited
Biological Process (BP)cellular component movement3.967e-060InformativeDirect
Biological Process (BP)regulation of anatomical structure morphogenesis4.096e-080InformativeDirect
Biological Process (BP)cell projection organization0.00054840InformativeDirect
Biological Process (BP)locomotion9.7e-100InformativeDirect
Biological Process (BP)generation of neurons1.431e-070InformativeDirect
Biological Process (BP)localization of cell0.00019750InformativeDirect
Biological Process (BP)regulation of cell development7.639e-070InformativeDirect
Biological Process (BP)epithelium development0.3490.2112InformativeInherited
Biological Process (BP)cellular component morphogenesis0.0037790InformativeInherited
Biological Process (BP)regulation of nervous system development0.023531.199e-06InformativeInherited
Biological Process (BP)tissue morphogenesis0.0011830.002994InformativeInherited
Biological Process (BP)chemotaxis6.044e-070Highly InformativeDirect
Biological Process (BP)regulation of cell morphogenesis involved in differentiation1.925e-083.931e-13Highly InformativeDirect
Biological Process (BP)regulation of neuron projection development3.222e-083.744e-06Highly InformativeDirect
Biological Process (BP)cell morphogenesis involved in neuron differentiation1.088e-070Highly InformativeDirect
Biological Process (BP)cell projection morphogenesis3.659e-070Highly InformativeDirect
Biological Process (BP)axon development9.979e-082.376e-09Highly InformativeDirect
Molecular Function (MF)binding0.015493.388e-09Least InformativeInherited
Molecular Function (MF)receptor binding0.00045420InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 5.618e-15 Least Informative Direct
Biological Process (BP) regulation of cellular process 0 Least Informative Direct
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) localization 0.001034 Least Informative Inherited
Biological Process (BP) signal transduction 0 Moderately Informative Direct
Biological Process (BP) nervous system development 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 5.681e-13 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 1.242e-06 Moderately Informative Direct
Biological Process (BP) cell differentiation 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 0 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.0001719 Moderately Informative Direct
Biological Process (BP) positive regulation of response to stimulus 1.786e-12 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 7.856e-05 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 9.759e-09 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 6.463e-09 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.003783 Moderately Informative Inherited
Biological Process (BP) tissue development 0.3695 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.8088 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.9228 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) homeostatic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.3579 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) regulation of protein phosphorylation 4.826e-06 Informative Direct
Biological Process (BP) cellular component movement 0 Informative Direct
Biological Process (BP) central nervous system development 7.875e-05 Informative Direct
Biological Process (BP) regulation of nucleoside metabolic process 2.588e-06 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0 Informative Direct
Biological Process (BP) cell projection organization 0 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 0.0001227 Informative Direct
Biological Process (BP) regulation of response to external stimulus 0 Informative Direct
Biological Process (BP) cellular component morphogenesis 0 Informative Direct
Biological Process (BP) regulation of growth 5.907e-05 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) regulation of locomotion 0 Informative Direct
Biological Process (BP) single-organism behavior 1.828e-05 Informative Direct
Biological Process (BP) generation of neurons 0 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 4.954e-05 Informative Direct
Biological Process (BP) regulation of cellular component movement 0 Informative Direct
Biological Process (BP) organelle localization 0.000549 Informative Direct
Biological Process (BP) localization of cell 0 Informative Direct
Biological Process (BP) regulation of nervous system development 1.199e-06 Informative Direct
Biological Process (BP) regulation of cell development 0 Informative Direct
Biological Process (BP) regulation of anatomical structure size 1.501e-11 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 1.496e-05 Informative Direct
Biological Process (BP) positive regulation of protein modification process 0.01372 Informative Inherited
Biological Process (BP) positive regulation of phosphate metabolic process 0.1186 Informative Inherited
Biological Process (BP) epithelium development 0.2112 Informative Inherited
Biological Process (BP) tissue morphogenesis 0.002994 Informative Inherited
Biological Process (BP) gland development 0.1497 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.00363 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 1 Informative Inherited
Biological Process (BP) phosphorylation 0.05497 Informative Inherited
Biological Process (BP) muscle structure development 0.8299 Informative Inherited
Biological Process (BP) regulation of kinase activity 0.9939 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.1163 Informative Inherited
Biological Process (BP) muscle tissue development 0.5408 Informative Inherited
Biological Process (BP) positive regulation of transport 0.1821 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.08596 Informative Inherited
Biological Process (BP) tube development 0.007742 Informative Inherited
Biological Process (BP) cardiovascular system development 0.1516 Informative Inherited
Biological Process (BP) angiogenesis 8.742e-07 Highly Informative Direct
Biological Process (BP) chemotaxis 0 Highly Informative Direct
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.0004346 Highly Informative Direct
Biological Process (BP) regulation of cell size 0 Highly Informative Direct
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 3.931e-13 Highly Informative Direct
Biological Process (BP) regulation of neuron projection development 3.744e-06 Highly Informative Direct
Biological Process (BP) regulation of cell adhesion 3.559e-05 Highly Informative Direct
Biological Process (BP) negative regulation of cell growth 1.69e-09 Highly Informative Direct
Biological Process (BP) positive regulation of cell migration 0.0002173 Highly Informative Direct
Biological Process (BP) positive regulation of response to external stimulus 0 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 5.469e-07 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 1.011e-07 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 1.186e-07 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in neuron differentiation 0 Highly Informative Direct
Biological Process (BP) cell projection morphogenesis 0 Highly Informative Direct
Biological Process (BP) regulation of behavior 0 Highly Informative Direct
Biological Process (BP) mesenchyme development 0.0001189 Highly Informative Direct
Biological Process (BP) axon development 2.376e-09 Highly Informative Direct
Biological Process (BP) positive regulation of protein kinase activity 0.1889 Highly Informative Inherited
Biological Process (BP) regulation of organ morphogenesis 0.3632 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.004889 Highly Informative Inherited
Biological Process (BP) negative regulation of response to external stimulus 0.0621 Highly Informative Inherited
Biological Process (BP) protein phosphorylation 0.01445 Highly Informative Inherited
Biological Process (BP) muscle organ development 0.3307 Highly Informative Inherited
Biological Process (BP) stem cell development 0.285 Highly Informative Inherited
Biological Process (BP) pattern specification process 0.1639 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 0.3581 Highly Informative Inherited
Molecular Function (MF) binding 3.388e-09 Least Informative Direct
Molecular Function (MF) transferase activity 0.8428 Least Informative Inherited
Molecular Function (MF) anion binding 0.00718 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.1406 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) receptor binding 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) carbohydrate derivative binding 1.066e-07 Informative Direct
Molecular Function (MF) sulfur compound binding 1.405e-08 Informative Direct
Molecular Function (MF) kinase activity 0.06368 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.03578 Informative Inherited
Molecular Function (MF) heparin binding 1.94e-07 Highly Informative Direct
Molecular Function (MF) protein kinase activity 0.006581 Highly Informative Inherited
Cellular Component (CC) membrane 3.049e-10 Least Informative Direct
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) plasma membrane 3.408e-07 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 2.388e-06 Moderately Informative Direct
Cellular Component (CC) extracellular region part 0.0009496 Moderately Informative Direct
Cellular Component (CC) integral to membrane 8.216e-10 Informative Direct
Cellular Component (CC) receptor complex 5.461e-05 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Receptor protein-tyrosine kinase0InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0Least InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.001502Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.2133Least InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.00503Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.01303Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic nervous system morphology0.07636Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.5473Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.6825Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal retinal neuronal layer morphology3.293e-05InformativeDirect
Mammalian Phenotype (MP)ectopic neuron0.002895InformativeInherited
Mammalian Phenotype (MP)abnormal metencephalon morphology0.008687InformativeInherited
Mammalian Phenotype (MP)abnormal neuron physiology0.02055InformativeInherited
Mammalian Phenotype (MP)abnormal cerebrum morphology0.3965InformativeInherited
Mammalian Phenotype (MP)ectopic cerebellar granule cells3.422e-08Highly InformativeDirect
Mammalian Phenotype (MP)abnormal amacrine cell morphology1.027e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal retinal inner plexiform layer morphology2.947e-06Highly InformativeDirect
Mammalian Phenotype (MP)abnormal neuronal migration0.0001376Highly InformativeDirect
Mammalian Phenotype (MP)abnormal hippocampus morphology0.1995Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cranial nerve morphology0.2854Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organ system development variant0.0003446Moderately InformativeDirect
Worm Phenotype (WP)male morphology variant1.081e-11InformativeDirect
Worm Phenotype (WP)anchor cell invasion variant2.861e-09InformativeDirect
Worm Phenotype (WP)sensillum morphology variant3.069e-09InformativeDirect
Worm Phenotype (WP)male nervous system morphology variant4.286e-13Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)neuroanatomy defective0Moderately InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)anatomical group0.1388Least InformativeInherited
Fly Anatomy (FA)larva0.2232Least InformativeInherited
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)multi-cell-component structure0Moderately InformativeDirect
Fly Anatomy (FA)late embryo0.02865Moderately InformativeInherited
Fly Anatomy (FA)central nervous system0.04467Moderately InformativeInherited
Fly Anatomy (FA)developing material anatomical entity0.08816Moderately InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.09905Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval peripheral nervous system2.732e-06InformativeDirect
Fly Anatomy (FA)nerve1.611e-05InformativeDirect
Fly Anatomy (FA)larval abdominal segment5.547e-05InformativeDirect
Fly Anatomy (FA)neuromere0.0001537InformativeDirect
Fly Anatomy (FA)ipsilateral tract0.0005136InformativeDirect
Fly Anatomy (FA)embryonic/larval central nervous system0.3659InformativeInherited
Fly Anatomy (FA)abdominal segmental nerve5.368e-08Highly InformativeDirect
Fly Anatomy (FA)intersegmental nerve6.461e-07Highly InformativeDirect
Fly Anatomy (FA)fascicle9.23e-06Highly InformativeDirect
Fly Anatomy (FA)presumptive embryonic/larval central nervous system0.0002828Highly InformativeDirect
Fly Anatomy (FA)longitudinal connective0.0002828Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.4462Least InformativeInherited
Xenopus ANatomical entity (XAN)portion of tissue1Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.1956Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.2873Moderately InformativeInherited
Xenopus ANatomical entity (XAN)cranial placode0.0002276InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Protein-tyrosine kinases0InformativeDirect
Enzyme Commission (EC)Receptor protein-tyrosine kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDifferentiation0Moderately InformativeDirect
Biological processNeurogenesis0InformativeDirect
Biological processAngiogenesis1.673e-13InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentSecreted4.141e-10Moderately InformativeDirect
DiseaseProto-oncogene0Moderately InformativeDirect
DomainSignal0Least InformativeDirect
DomainTransmembrane0Least InformativeDirect
DomainRepeat8.032e-06Least InformativeDirect
DomainImmunoglobulin domain0InformativeDirect
Post-translational modificationTransferase0.1251Least InformativeInherited
Post-translational modificationDevelopmental protein0Moderately InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationReceptor0Moderately InformativeDirect
Post-translational modificationTyrosine-protein kinase0Highly InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect
Post-translational modificationUbl conjugation8.782e-15Moderately InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001627 SSF101912 Protein matches
Abstract

The Sema domain occurs in semaphorins, which are a large family of secreted and transmembrane proteins, some of which function as repellent signals during axon guidance. Sema domains also occur in a hepatocyte growth factor receptor, in SEX protein [PubMed9875845] and in viral proteins.

CD100 (also called SEMA4D) is associated with PTPase and serine kinase activity. CD100 increases PMA, CD3 and CD2 induced T cell proliferation, increases CD45 induced T cell adhesion, induces B cell homotypic adhesion and down-regulates B cell expression of CD23.

The Sema domain is characterised by a conserved set of cysteine residues, which form four disulphide bonds to stabilise the structure. The Sema domain fold is a variation of the beta propeller topology, with seven blades radially arranged around a central axis. Each blade contains a four- stranded (strands A to D) antiparallel beta sheet. The inner strand of each blade (A) lines the channel at the centre of the propeller, with strands B and C of the same repeat radiating outward, and strand D of the next repeat forming the outer edge of the blade. The large size of the Sema domain is not due to a single inserted domain but results from the presence of additionnal secondary structure elements inserted in most of the blades. The Sema domain uses a 'loop and hook' system to close the circle between the first and the last blades. The blades are constructed sequentially with an N-terminal beta- strand closing the circle by providing the outermost strand (D) of the seventh (C-terminal) blade. The beta-propeller is further stabilized by an extension of the N-terminus, providing an additional, fifth beta-strand on the outer edge of blade 6 [PubMed12925274, PubMed12958590, PubMed15167892].

CD molecules are leucocyte antigens on cell surfaces. CD antigens nomenclature is updated at Protein Reviews On The Web (http://mpr.nci.nih.gov/prow/).


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Sema domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the Sema domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]