SUPERFAMILY 1.75 HMM library and genome assignments server


Supernatant protein factor (SPF), C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Supernatant protein factor (SPF), C-terminal domain [ 101575]
Superfamily:   Supernatant protein factor (SPF), C-terminal domain [ 101576]
Families:   Supernatant protein factor (SPF), C-terminal domain [ 101577]


Superfamily statistics
Genomes (423) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 2,648 2,387 2
Proteins 2,645 2,384 2


Functional annotation
General category General
Detailed category Ligand binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) localization 0.08904 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.878 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.821 Least Informative Inherited
Biological Process (BP) cellular localization 0.0005795 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.8634 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.219 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.2224 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.1107 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.3053 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.3393 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.05868 Moderately Informative Inherited
Biological Process (BP) regulation of reproductive process 3.593e-05 Informative Direct
Biological Process (BP) regulation of protein localization 0.0003813 Informative Direct
Biological Process (BP) regulation of secretion 0.0005316 Informative Direct
Biological Process (BP) positive regulation of transport 0.001019 Informative Inherited
Biological Process (BP) regulation of behavior 7.353e-07 Highly Informative Direct
Biological Process (BP) regulation of protein secretion 1.641e-06 Highly Informative Direct
Biological Process (BP) positive regulation of protein transport 3.547e-06 Highly Informative Direct
Biological Process (BP) regulation of multi-organism process 6.343e-06 Highly Informative Direct
Biological Process (BP) positive regulation of secretion 1.224e-05 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 2.964e-08 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 3.819e-05 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.8681 Least Informative Inherited
Cellular Component (CC) membrane 0.2281 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 1.639e-14 Moderately Informative Direct
Cellular Component (CC) vesicle 4.892e-06 Moderately Informative Direct
Cellular Component (CC) endomembrane system 7.803e-05 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.009209 Moderately Informative Inherited
Cellular Component (CC) Golgi apparatus 6.065e-11 Informative Direct
Cellular Component (CC) coated vesicle 1.843e-05 Informative Direct
Cellular Component (CC) cis-Golgi network 2.858e-10 Highly Informative Direct
Cellular Component (CC) vesicle membrane 1.08e-07 Highly Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 2.21e-06 Highly Informative Direct
Cellular Component (CC) Golgi-associated vesicle 3.405e-06 Highly Informative Direct
Cellular Component (CC) Golgi membrane 0.0005327 Highly Informative Direct
Cellular Component (CC) transport vesicle 0.0008717 Highly Informative Direct

Document: GO annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)intracellular transport0.0007778InformativeDirect

Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot internode0Least InformativeDirect
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)pedicel0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant ANatomical entity (PAN)microgametophyte0Least InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)vitamins0Least InformativeDirect
Drugbank ATC_code (DB)other plain vitamin preparations1Moderately InformativeInherited
Drugbank ATC_code (DB)tocopherol (vit e)0InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport1.183e-14Moderately InformativeDirect
Biological processER-Golgi transport9.037e-11Highly InformativeDirect
Cellular componentMembrane1.208e-14Least InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
DomainSignal9.471e-12Least InformativeDirect
DomainTransmembrane2.057e-08Least InformativeDirect
DomainCoiled coil2.914e-12Moderately InformativeDirect
Molecular functionLipid-binding0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Supernatant protein factor (SPF), C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Supernatant protein factor (SPF), C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · Internal database links ]