SUPERFAMILY 1.75 HMM library and genome assignments server


DhaL-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   DhaL-like [ 101472]
Superfamily:   DhaL-like [ 101473]
Families:   DhaL-like [ 101474] (2)


Superfamily statistics
Genomes (1,719) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 2,798 18,940 3
Proteins 2,795 18,934 3


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.02568 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1.129e-05 Moderately Informative Direct
Biological Process (BP) organic hydroxy compound metabolic process 8.076e-06 Moderately Informative Direct
Biological Process (BP) alcohol metabolic process 9.001e-07 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 7.619e-08 Informative Direct
Biological Process (BP) polyol metabolic process 1.124e-08 Highly Informative Direct
Molecular Function (MF) transferase activity 0.001572 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.04568 Moderately Informative Inherited
Molecular Function (MF) kinase activity 0.0001815 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0.0001031 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorous-containing groups0Least InformativeDirect
Enzyme Commission (EC)Lyases0.001465Least InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Phosphorus-oxygen lyases1InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processGlycerol metabolism0Highly InformativeDirect
Molecular functionNucleotide-binding2.544e-10Least InformativeDirect
Molecular functionATP-binding1.413e-11Moderately InformativeDirect
Molecular functionFlavoprotein7.618e-06Moderately InformativeDirect
Molecular functionManganese2.862e-05Moderately InformativeDirect
Molecular functionCobalt1.113e-09InformativeDirect
Molecular functionFAD1.494e-07InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationKinase0Moderately InformativeDirect
Post-translational modificationLyase0.0001523Moderately InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)alcohol metabolism0Moderately InformativeDirect
UniPathway (UP)glycerol metabolism0InformativeDirect
UniPathway (UP)fermentation0InformativeDirect
UniPathway (UP)polyol degradation0InformativeDirect
UniPathway (UP)glycerol fermentation1.415e-13Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR004007 SSF101473 Protein matches
Abstract Dihydroxyacetone kinase (glycerone kinase) catalyses the phosphorylation of glycerone in the presence of ATP to glycerone phosphate in the glycerol utilization pathway. This is the predicted phosphatase domain of the dihydroxyacetone kinase family.

InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DhaL-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the DhaL-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]