SUPERFAMILY 1.75 HMM library and genome assignments server


Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) [ 101352]
Superfamily:   Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) [ 101353]
Families:   Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) [ 101354]


Superfamily statistics
Genomes (3,209) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 3,639 17,829 1
Proteins 3,629 17,819 1


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 3.836e-13 Least Informative Direct
Biological Process (BP) protein metabolic process 6.502e-13 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 4.349e-10 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 1.07e-06 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 1.442e-06 Least Informative Direct
Biological Process (BP) single-organism metabolic process 1.502e-06 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 3.111e-06 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 3.237e-06 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.05748 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.522 Least Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 3.364e-09 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.0004578 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 0.0264 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.02766 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.03445 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.02087 Moderately Informative Inherited
Biological Process (BP) ncRNA metabolic process 0 Informative Direct
Biological Process (BP) posttranscriptional regulation of gene expression 1.403e-06 Informative Direct
Biological Process (BP) regulation of translation 3.495e-08 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.6211 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 5.941e-05 Moderately Informative Direct
Molecular Function (MF) ligase activity 3.933e-11 Informative Direct
Molecular Function (MF) carboxylic ester hydrolase activity 1.503e-09 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.005037 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.3271 Least Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compoun0Moderately InformativeDirect
Enzyme Commission (EC)Alanine--tRNA ligase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases forming aminoacyl-tRNA and related compounds0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionRNA-binding0Moderately InformativeDirect
Molecular functiontRNA-binding0InformativeDirect
Post-translational modificationLigase0Moderately InformativeDirect
Post-translational modificationAminoacyl-tRNA synthetase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]