SUPERFAMILY 1.75 HMM library and genome assignments server

PWI domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   PWI domain [ 101232]
Superfamily:   PWI domain [ 101233]
Families:   PWI domain [ 101234]


Superfamily statistics
Genomes (434) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 1,104 1,151 1
Proteins 1,102 1,150 1


Functional annotation
General category Regulation
Detailed category RNA binding, metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) heterocycle metabolic process 0.00002641 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.00003203 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.00007094 Least Informative Direct
Biological Process (BP) nitrogen compound metabolic process 0.0002073 Least Informative Direct
Biological Process (BP) cellular macromolecule metabolic process 0.0009539 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0.4149 Least Informative Inherited
Biological Process (BP) RNA metabolic process 0.000000001509 Moderately Informative Direct
Biological Process (BP) gene expression 0.000000008094 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.007811 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.009267 Moderately Informative Inherited
Biological Process (BP) RNA processing 0.0000000000002478 Informative Direct
Biological Process (BP) ribonucleoprotein complex biogenesis 0.000001147 Informative Direct
Biological Process (BP) cellular macromolecular complex assembly 0.00001242 Informative Direct
Biological Process (BP) ribonucleoprotein complex subunit organization 0.00000001503 Highly Informative Direct
Biological Process (BP) mRNA processing 0.00002198 Highly Informative Direct
Biological Process (BP) RNA splicing 0.00004218 Highly Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.02036 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0.0002326 Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.000000009425 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.000004123 Least Informative Direct
Cellular Component (CC) ribonucleoprotein complex 0.0000000000005945 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.00000001952 Moderately Informative Direct
Cellular Component (CC) spliceosomal complex 0.00000000000000158 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processmRNA splicing0.0004418InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentSpliceosome0InformativeDirect
Molecular functionRNA-binding0.00007179Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.0000000000001159Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a PWI domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the PWI domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]