SUPERFAMILY 1.75 HMM library and genome assignments server

Plant invertase/pectin methylesterase inhibitor superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bromodomain-like [ 47363] (15)
Superfamily:   Plant invertase/pectin methylesterase inhibitor [ 101148]
Families:   Plant invertase/pectin methylesterase inhibitor [ 101149] (2)


Superfamily statistics
Genomes (57) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 4,827 3,285 5
Proteins 4,770 3,263 5


Functional annotation
General category coiled coil
Detailed category The code refers to 4-helix bundles. These are a type of structure which frequently contain coiled-coils.

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis0.000024650.0003741Least InformativeDirect
Biological Process (BP)regulation of metabolic process0.0032350.5286Least InformativeInherited
Biological Process (BP)multicellular organismal process0.000054550.015Least InformativeInherited
Biological Process (BP)single-organism cellular process0.0081081Least InformativeInherited
Biological Process (BP)developmental process0.000025780.00806Least InformativeInherited
Biological Process (BP)reproductive process0.0000014330.00003503Moderately InformativeDirect
Biological Process (BP)multi-organism process0.000027220.00000002071Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.017510.01935Moderately InformativeInherited
Biological Process (BP)negative regulation of metabolic process0.000099060.06788Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.000086160.01658Moderately InformativeInherited
Biological Process (BP)cell differentiation0.00000043350.00243Moderately InformativeInherited
Biological Process (BP)growth0.00000021020.000005319InformativeDirect
Biological Process (BP)negative regulation of catalytic activity0.0000024960.00003663InformativeDirect
Biological Process (BP)single organism reproductive process0.0000029380.00007324InformativeDirect
Biological Process (BP)multi-multicellular organism process0.00000040220.00000186InformativeDirect
Biological Process (BP)cellular component morphogenesis0.000092020.01607InformativeInherited
Biological Process (BP)cell morphogenesis involved in differentiation0.0000000039410.0008996Highly InformativeDirect
Biological Process (BP)cell growth0.0000000046720.000000008835Highly InformativeDirect
Biological Process (BP)developmental growth0.0000021420.0000001726Highly InformativeDirect
Molecular Function (MF)enzyme regulator activity0.0000066910.000134Moderately InformativeDirect
Molecular Function (MF)enzyme inhibitor activity0.00000066120.0000002607InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.0003741 Least Informative Direct
Biological Process (BP) response to stimulus 0.0282 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.5286 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.015 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) developmental process 0.00806 Least Informative Inherited
Biological Process (BP) reproductive process 0.00003503 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.00000002071 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.01935 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.03866 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 0.06788 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.01658 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.00243 Moderately Informative Inherited
Biological Process (BP) growth 0.000005319 Informative Direct
Biological Process (BP) negative regulation of catalytic activity 0.00003663 Informative Direct
Biological Process (BP) single organism reproductive process 0.00007324 Informative Direct
Biological Process (BP) multi-multicellular organism process 0.00000186 Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.000000532 Informative Direct
Biological Process (BP) cellular component morphogenesis 0.01607 Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.0008996 Highly Informative Direct
Biological Process (BP) cell growth 0.000000008835 Highly Informative Direct
Biological Process (BP) developmental growth 0.0000001726 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.04589 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.0000677 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 0.000134 Moderately Informative Direct
Molecular Function (MF) enzyme inhibitor activity 0.0000002607 Informative Direct
Molecular Function (MF) carboxylic ester hydrolase activity 0.00000000006232 Highly Informative Direct
Cellular Component (CC) cell projection 0.003307 Moderately Informative Inherited
Cellular Component (CC) external encapsulating structure 0.00003462 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell wall biogenesis/degradation0InformativeDirect
Cellular componentSecreted0Moderately InformativeDirect
Cellular componentCell wall0Highly InformativeDirect
DomainSignal0Least InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect
Post-translational modificationDisulfide bond0Least InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)glycan metabolism0Moderately InformativeDirect
UniPathway (UP)glycan degradation0InformativeDirect
UniPathway (UP)pectin degradation0Highly InformativeDirect

Document: UP annotation of SCOP domains

InterPro annotation
Cross references IPR006501 SSF101148 Protein matches
Abstract

These sequences contain a plant domain of about 200 amino acids, characterised by four conserved cysteine residues. The functional importance of these residues has been studied in a pectinesterase inhibitor from Kiwi. The cysteine residues form two disulphide bonds: first to second and third to fourth [PubMed10880981]. Roughly half the members of this family have an adjacent C-terminal pectinesterase domain , suggesting that the pairing of the enzymatic domain and the cysteine domain reflect a conserved regulatory mechanism for this enzyme family.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Plant invertase/pectin methylesterase inhibitor domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Plant invertase/pectin methylesterase inhibitor superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]