SUPERFAMILY 1.75 HMM library and genome assignments server


NagB/RpiA/CoA transferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   NagB/RpiA/CoA transferase-like [ 100949]
Superfamily:   NagB/RpiA/CoA transferase-like [ 100950] (8)
Families:   NagB-like [ 52513] (2)
  D-ribose-5-phosphate isomerase (RpiA), catalytic domain [ 75176]
  CoA transferase beta subunit-like [ 74657] (3)
  CoA transferase alpha subunit-like [ 74656] (6)
  IF2B-like [ 110513] (5)
  Methenyltetrahydrofolate synthetase [ 110520] (3)
  YkgG-like [ 142200]
  SorC sugar-binding domain-like [ 159545] (5)


Superfamily statistics
Genomes (3,198) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,377 219,592 41
Proteins 31,205 196,804 34


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.8851Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.013070.4451Least InformativeInherited
Biological Process (BP)regulation of cellular process0.73031Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)multicellular organismal process0.34991Least InformativeInherited
Biological Process (BP)developmental process0.027681Least InformativeInherited
Biological Process (BP)localization0.94691Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.980.01281Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.81231Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.99351Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.9541Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.5791Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.71070.2657Least InformativeInherited
Biological Process (BP)protein metabolic process0.13010.9359Least InformativeInherited
Biological Process (BP)gene expression1.87e-061.673e-10Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process5.901e-074.443e-11Moderately InformativeDirect
Biological Process (BP)regulation of catalytic activity3.424e-068.052e-05Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process2.583e-060Moderately InformativeDirect
Biological Process (BP)carbohydrate metabolic process0.093422.05e-06Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.015550.001455Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.00011380.04149Moderately InformativeInherited
Biological Process (BP)response to organic substance0.58020.9511Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.29230.1794Moderately InformativeInherited
Biological Process (BP)regulation of phosphate metabolic process10.0003247Moderately InformativeInherited
Biological Process (BP)system process0.022720.3196Moderately InformativeInherited
Biological Process (BP)cell differentiation0.00073110.3629Moderately InformativeInherited
Biological Process (BP)nervous system development0.00015160.05948Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.05010.09701Moderately InformativeInherited
Biological Process (BP)organ development0.65551Moderately InformativeInherited
Biological Process (BP)cellular localization0.21470.6484Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.15670.1905Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.13041Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.170.002776Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.01590.0001752Moderately InformativeInherited
Biological Process (BP)regulation of biosynthetic process0.95970.9888Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.35170.8472Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.85390.6927Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.016230.3287Moderately InformativeInherited
Biological Process (BP)reproduction0.00012690.03298Moderately InformativeInherited
Biological Process (BP)translation9.415e-130InformativeDirect
Biological Process (BP)central nervous system development1.362e-084.161e-05InformativeDirect
Biological Process (BP)regulation of nucleoside metabolic process2.362e-095.784e-12InformativeDirect
Biological Process (BP)regulation of cellular catabolic process4.584e-097.019e-09InformativeDirect
Biological Process (BP)single organism reproductive process5.723e-081.811e-05InformativeDirect
Biological Process (BP)positive regulation of hydrolase activity2.574e-105.27e-07InformativeDirect
Biological Process (BP)pyridine-containing compound metabolic process6.6e-090InformativeDirect
Biological Process (BP)regulation of purine nucleotide metabolic process9.377e-111.249e-10InformativeDirect
Biological Process (BP)carbohydrate derivative catabolic process0.0010390.2977InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.03299.555e-05InformativeInherited
Biological Process (BP)multicellular organismal reproductive process0.54230.1293InformativeInherited
Biological Process (BP)vesicle-mediated transport0.034240.4301InformativeInherited
Biological Process (BP)secretion by cell9.403e-050.03807InformativeInherited
Biological Process (BP)sexual reproduction0.14830.5115InformativeInherited
Biological Process (BP)cellular process involved in reproduction0.0070320.2795InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00032510.02184InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression0.0057490.005203InformativeInherited
Biological Process (BP)carbohydrate catabolic process0.011541.736e-08InformativeInherited
Biological Process (BP)hexose metabolic process1.87e-060.05501InformativeInherited
Biological Process (BP)reproductive system development0.004160.002504InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.18940.01344InformativeInherited
Biological Process (BP)amino sugar metabolic process00Highly InformativeDirect
Biological Process (BP)translational initiation00Highly InformativeDirect
Biological Process (BP)regulation of translation0.00050216.041e-05Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process1.228e-060.0004362Highly InformativeDirect
Biological Process (BP)gonad development7.896e-061.904e-07Highly InformativeDirect
Biological Process (BP)response to heat0.00044073.568e-06Highly InformativeDirect
Biological Process (BP)response to carbohydrate stimulus6.434e-050.0004398Highly InformativeDirect
Biological Process (BP)glial cell differentiation4.591e-137.377e-15Highly InformativeDirect
Biological Process (BP)ovulation cycle process9.757e-082.387e-11Highly InformativeDirect
Biological Process (BP)regulation of membrane potential3.926e-074.185e-07Highly InformativeDirect
Biological Process (BP)nicotinamide nucleotide metabolic process2.137e-100Highly InformativeDirect
Biological Process (BP)development of primary female sexual characteristics1.756e-072.91e-10Highly InformativeDirect
Biological Process (BP)exocytosis8.935e-060.001476Highly InformativeInherited
Biological Process (BP)fertilization0.00040540.004234Highly InformativeInherited
Molecular Function (MF)binding0.3581Least InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)transferase activity10.6884Least InformativeInherited
Molecular Function (MF)isomerase activity4.022e-140Moderately InformativeDirect
Molecular Function (MF)enzyme regulator activity2.243e-081.481e-09Moderately InformativeDirect
Molecular Function (MF)hydrolase activity, acting on ester bonds0.0025347.31e-07Moderately InformativeInherited
Molecular Function (MF)anion binding0.0077440.08722Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding1.458e-110.001535Moderately InformativeInherited
Molecular Function (MF)RNA binding9.29e-056.121e-11InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity00InformativeDirect
Molecular Function (MF)GTPase regulator activity6.007e-142.052e-14InformativeDirect
Molecular Function (MF)nucleotide binding0.00054040.416InformativeInherited
Molecular Function (MF)ligase activity, forming carbon-nitrogen bonds1.072e-060.002354InformativeInherited
Molecular Function (MF)purine ribonucleoside binding9.501e-050.001035InformativeInherited
Molecular Function (MF)purine ribonucleoside triphosphate binding4.831e-050.001005InformativeInherited
Molecular Function (MF)guanyl-nucleotide exchange factor activity00Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding00Highly InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity, interconverting aldoses and ketoses00Highly InformativeDirect
Molecular Function (MF)deaminase activity00Highly InformativeDirect
Molecular Function (MF)carboxylic ester hydrolase activity3.959e-091.37e-10Highly InformativeDirect
Cellular Component (CC)protein complex0.0036320.1435Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.17532.259e-07Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.4451 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.01281 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.2657 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.9359 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 2.05e-06 Moderately Informative Direct
Biological Process (BP) gene expression 1.673e-10 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0.0003247 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 4.443e-11 Moderately Informative Direct
Biological Process (BP) regulation of catalytic activity 8.052e-05 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0001752 Moderately Informative Direct
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.04149 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.001455 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.9511 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.1794 Moderately Informative Inherited
Biological Process (BP) system process 0.3196 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.3629 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.05948 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.09701 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.6484 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.1905 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.002776 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 0.9888 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.8472 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.6927 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.6752 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.3287 Moderately Informative Inherited
Biological Process (BP) reproduction 0.03298 Moderately Informative Inherited
Biological Process (BP) translation 0 Informative Direct
Biological Process (BP) oxidoreduction coenzyme metabolic process 9.555e-05 Informative Direct
Biological Process (BP) central nervous system development 4.161e-05 Informative Direct
Biological Process (BP) regulation of nucleoside metabolic process 5.784e-12 Informative Direct
Biological Process (BP) carbohydrate catabolic process 1.736e-08 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 7.019e-09 Informative Direct
Biological Process (BP) single organism reproductive process 1.811e-05 Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 5.27e-07 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 1.249e-10 Informative Direct
Biological Process (BP) multicellular organismal reproductive process 0.1293 Informative Inherited
Biological Process (BP) cellular ketone metabolic process 0.001491 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.4301 Informative Inherited
Biological Process (BP) secretion by cell 0.03807 Informative Inherited
Biological Process (BP) sexual reproduction 0.5115 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.2795 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.02184 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.005203 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.2977 Informative Inherited
Biological Process (BP) hexose metabolic process 0.05501 Informative Inherited
Biological Process (BP) reproductive system development 0.002504 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.01344 Informative Inherited
Biological Process (BP) amino sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Biological Process (BP) regulation of translation 6.041e-05 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.0004362 Highly Informative Direct
Biological Process (BP) gonad development 1.904e-07 Highly Informative Direct
Biological Process (BP) response to heat 3.568e-06 Highly Informative Direct
Biological Process (BP) response to carbohydrate stimulus 0.0004398 Highly Informative Direct
Biological Process (BP) glial cell differentiation 7.377e-15 Highly Informative Direct
Biological Process (BP) pentose metabolic process 0.0001759 Highly Informative Direct
Biological Process (BP) ovulation cycle process 2.387e-11 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 4.185e-07 Highly Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0 Highly Informative Direct
Biological Process (BP) development of primary female sexual characteristics 2.91e-10 Highly Informative Direct
Biological Process (BP) exocytosis 0.001476 Highly Informative Inherited
Biological Process (BP) fertilization 0.004234 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.6884 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 7.31e-07 Moderately Informative Direct
Molecular Function (MF) isomerase activity 0 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 1.481e-09 Moderately Informative Direct
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.08722 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.001535 Moderately Informative Inherited
Molecular Function (MF) RNA binding 6.121e-11 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 0.0002912 Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity 0 Informative Direct
Molecular Function (MF) GTPase regulator activity 2.052e-14 Informative Direct
Molecular Function (MF) nucleotide binding 0.416 Informative Inherited
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 0.002354 Informative Inherited
Molecular Function (MF) purine ribonucleoside binding 0.001035 Informative Inherited
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.001005 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0001199 Highly Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0 Highly Informative Direct
Molecular Function (MF) deaminase activity 0 Highly Informative Direct
Molecular Function (MF) carboxylic ester hydrolase activity 1.37e-10 Highly Informative Direct
Molecular Function (MF) thiolester hydrolase activity 0.01571 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 2.259e-07 Least Informative Direct
Cellular Component (CC) protein complex 0.1435 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Ligases1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0Moderately InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases1.442e-14Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c0InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases2.533e-05InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.01457InformativeInherited
Enzyme Commission (EC)In other compounds0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.04629Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.2586Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of brain morphology0.1358Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the genital system0.2515Moderately InformativeInherited
Phenotypic Abnormality (PA)Puberty and gonadal disorders0.001328InformativeInherited
Phenotypic Abnormality (PA)Abnormality of female internal genitalia0.003922InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebrum1InformativeInherited
Phenotypic Abnormality (PA)Leukoencephalopathy3.637e-06Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.0001124Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases7.078e-15InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds0Highly InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.004223Highly InformativeInherited
Enzyme Commission (EC)Oxo-acid-lyases0.2686Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Post-translational modificationHydrolase1.392e-06Least InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationRepressor1.92e-06Moderately InformativeDirect
Post-translational modificationInitiation factor1.542e-08InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)amino-acid metabolism0.2365Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)carbohydrate degradation0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis6.755e-16Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)amino-sugar metabolism0InformativeDirect
UniPathway (UP)amine and polyamine degradation0InformativeDirect
UniPathway (UP)L-methionine biosynthesis0InformativeDirect
UniPathway (UP)pentose phosphate pathway0Highly InformativeDirect
UniPathway (UP)N-acetylneuraminate degradation0Highly InformativeDirect
UniPathway (UP)L-methionine biosynthesis via salvage pathway0Highly InformativeDirect
UniPathway (UP)beta-ketoadipate pathway4.604e-07Highly InformativeDirect
UniPathway (UP)ketone degradation1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a NagB/RpiA/CoA transferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the NagB/RpiA/CoA transferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]