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NagB/RpiA/CoA transferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   NagB/RpiA/CoA transferase-like [ 100949]
Superfamily:   NagB/RpiA/CoA transferase-like [ 100950] (8)
Families:   NagB-like [ 52513] (2)
  D-ribose-5-phosphate isomerase (RpiA), catalytic domain [ 75176]
  CoA transferase beta subunit-like [ 74657] (3)
  CoA transferase alpha subunit-like [ 74656] (6)
  IF2B-like [ 110513] (5)
  Methenyltetrahydrofolate synthetase [ 110520] (3)
  YkgG-like [ 142200]
  SorC sugar-binding domain-like [ 159545] (5)


Superfamily statistics
Genomes (3,198) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 34,381 219,592 41
Proteins 31,209 196,804 34


Functional annotation
General category Metabolism
Detailed category Transferases

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus0.88971Least InformativeInherited
Biological Process (BP)regulation of metabolic process0.087140.6446Least InformativeInherited
Biological Process (BP)regulation of cellular process0.98171Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)multicellular organismal process0.33861Least InformativeInherited
Biological Process (BP)developmental process0.025241Least InformativeInherited
Biological Process (BP)localization0.94551Least InformativeInherited
Biological Process (BP)single-organism metabolic process0.99280.01121Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.81821Least InformativeInherited
Biological Process (BP)nitrogen compound metabolic process0.99771Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.95951Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.58291Least InformativeInherited
Biological Process (BP)cellular macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)biosynthetic process0.72750.2388Least InformativeInherited
Biological Process (BP)protein metabolic process0.12080.9263Least InformativeInherited
Biological Process (BP)gene expression0.0000011380.00000000007188Moderately InformativeDirect
Biological Process (BP)cellular macromolecule biosynthetic process0.00000039340.00000000002092Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.0000034710Moderately InformativeDirect
Biological Process (BP)organic substance catabolic process0.00034590.00002528Moderately InformativeDirect
Biological Process (BP)carbohydrate metabolic process0.094510.000002486Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.078840.005966Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.00088380.002388Moderately InformativeInherited
Biological Process (BP)regulation of nucleobase-containing compound metabolic process0.013890.1573Moderately InformativeInherited
Biological Process (BP)response to organic substance0.55630.93Moderately InformativeInherited
Biological Process (BP)response to oxygen-containing compound0.27560.1651Moderately InformativeInherited
Biological Process (BP)regulation of phosphate metabolic process10.009204Moderately InformativeInherited
Biological Process (BP)system process0.023450.2875Moderately InformativeInherited
Biological Process (BP)regulation of biological quality0.25891Moderately InformativeInherited
Biological Process (BP)cell differentiation0.0004950.3015Moderately InformativeInherited
Biological Process (BP)nervous system development0.00015020.04694Moderately InformativeInherited
Biological Process (BP)response to abiotic stimulus0.044890.08761Moderately InformativeInherited
Biological Process (BP)organ development0.66021Moderately InformativeInherited
Biological Process (BP)cellular localization0.19470.6116Moderately InformativeInherited
Biological Process (BP)cellular amino acid metabolic process0.15840.2029Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.12151Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.18940.003449Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.018250.0002554Moderately InformativeInherited
Biological Process (BP)regulation of gene expression0.33870.8071Moderately InformativeInherited
Biological Process (BP)regulation of macromolecule biosynthetic process0.21730.5552Moderately InformativeInherited
Biological Process (BP)regulation of cellular biosynthetic process0.80080.8448Moderately InformativeInherited
Biological Process (BP)regulation of protein metabolic process0.58970.6038Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.019220.3589Moderately InformativeInherited
Biological Process (BP)reproduction0.00011110.0251Moderately InformativeInherited
Biological Process (BP)central nervous system development0.000000011030.0000319InformativeDirect
Biological Process (BP)regulation of nucleoside metabolic process0.0000012120.000000008723InformativeDirect
Biological Process (BP)regulation of cellular catabolic process0.000017350.000003487InformativeDirect
Biological Process (BP)single organism reproductive process0.000000036910.00001245InformativeDirect
Biological Process (BP)positive regulation of hydrolase activity0.000002970.0000082InformativeDirect
Biological Process (BP)pyridine-containing compound metabolic process0.0000000064530InformativeDirect
Biological Process (BP)regulation of purine nucleotide metabolic process0.000001620.0000001253InformativeDirect
Biological Process (BP)carbohydrate derivative catabolic process0.0012460.3286InformativeInherited
Biological Process (BP)oxidoreduction coenzyme metabolic process0.02560.0001527InformativeInherited
Biological Process (BP)multicellular organismal reproductive process0.54080.1292InformativeInherited
Biological Process (BP)vesicle-mediated transport0.028990.402InformativeInherited
Biological Process (BP)secretion by cell0.000077140.03528InformativeInherited
Biological Process (BP)sexual reproduction0.14820.5153InformativeInherited
Biological Process (BP)cellular process involved in reproduction0.0068320.2811InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.00030010.02221InformativeInherited
Biological Process (BP)posttranscriptional regulation of gene expression0.0052430.004436InformativeInherited
Biological Process (BP)carbohydrate catabolic process0.010610.00000002486InformativeInherited
Biological Process (BP)hexose metabolic process0.0000014930.0534InformativeInherited
Biological Process (BP)reproductive system development0.0041120.001987InformativeInherited
Biological Process (BP)developmental process involved in reproduction0.18780.01065InformativeInherited
Biological Process (BP)amino sugar metabolic process00Highly InformativeDirect
Biological Process (BP)translational initiation00Highly InformativeDirect
Biological Process (BP)regulation of translation0.00047730.00004852Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process0.000001490.0005371Highly InformativeDirect
Biological Process (BP)gonad development0.0000077570.000000143Highly InformativeDirect
Biological Process (BP)response to heat0.00037660.000002857Highly InformativeDirect
Biological Process (BP)response to carbohydrate stimulus0.000057260.000385Highly InformativeDirect
Biological Process (BP)glial cell differentiation0.00000000000045430.000000000000003755Highly InformativeDirect
Biological Process (BP)ovulation cycle process0.000000063920.0000000000107Highly InformativeDirect
Biological Process (BP)regulation of membrane potential0.00000031360.0000003637Highly InformativeDirect
Biological Process (BP)positive regulation of GTPase activity0.000000014480.0000000002208Highly InformativeDirect
Biological Process (BP)nicotinamide nucleotide metabolic process0.00000000017140Highly InformativeDirect
Biological Process (BP)development of primary female sexual characteristics0.00000013890.0000000002093Highly InformativeDirect
Biological Process (BP)exocytosis0.0000095390.001397Highly InformativeInherited
Biological Process (BP)fertilization0.00051710.005083Highly InformativeInherited
Molecular Function (MF)binding0.34251Least InformativeInherited
Molecular Function (MF)hydrolase activity11Least InformativeInherited
Molecular Function (MF)transferase activity10.6255Least InformativeInherited
Molecular Function (MF)isomerase activity0.000000000000046470Moderately InformativeDirect
Molecular Function (MF)enzyme regulator activity0.000000017260.0000000009416Moderately InformativeDirect
Molecular Function (MF)anion binding0.0067530.07971Moderately InformativeInherited
Molecular Function (MF)hydrolase activity, acting on ester bonds0.0022030.000000529Moderately InformativeInherited
Molecular Function (MF)nucleic acid binding0.0000000000097340.001472Moderately InformativeInherited
Molecular Function (MF)RNA binding0.000096540.00000000005302InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity00InformativeDirect
Molecular Function (MF)GTPase regulator activity0.000000000000036550.00000000000001334InformativeDirect
Molecular Function (MF)purine ribonucleoside binding0.000074970.0007878InformativeDirect
Molecular Function (MF)purine ribonucleoside triphosphate binding0.000038190.0008467InformativeDirect
Molecular Function (MF)nucleotide binding0.00045830.4075InformativeInherited
Molecular Function (MF)ligase activity0.0003150.301InformativeInherited
Molecular Function (MF)guanyl-nucleotide exchange factor activity00Highly InformativeDirect
Molecular Function (MF)translation factor activity, nucleic acid binding00Highly InformativeDirect
Molecular Function (MF)intramolecular oxidoreductase activity, interconverting aldoses and ketoses00Highly InformativeDirect
Molecular Function (MF)deaminase activity00Highly InformativeDirect
Molecular Function (MF)carboxylic ester hydrolase activity0.0000000031890.000000000131Highly InformativeDirect
Cellular Component (CC)protein complex0.0025050.1452Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.23910.0000002434Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 0.6446 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.01121 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 0.2388 Least Informative Inherited
Biological Process (BP) protein metabolic process 0.9263 Least Informative Inherited
Biological Process (BP) localization 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.000002486 Moderately Informative Direct
Biological Process (BP) gene expression 0.00000000007188 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.00000000002092 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0002554 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.00002528 Moderately Informative Direct
Biological Process (BP) positive regulation of molecular function 0.005966 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.002388 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 0.1573 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.93 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 0.1651 Moderately Informative Inherited
Biological Process (BP) regulation of phosphate metabolic process 0.009204 Moderately Informative Inherited
Biological Process (BP) system process 0.2875 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 0.3015 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.04694 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.08761 Moderately Informative Inherited
Biological Process (BP) organ development 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.6116 Moderately Informative Inherited
Biological Process (BP) cellular amino acid metabolic process 0.2029 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.003449 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 0.8071 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 0.5552 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.8448 Moderately Informative Inherited
Biological Process (BP) regulation of protein metabolic process 0.6038 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.6368 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.1281 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.3589 Moderately Informative Inherited
Biological Process (BP) reproduction 0.0251 Moderately Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.0001527 Informative Direct
Biological Process (BP) central nervous system development 0.0000319 Informative Direct
Biological Process (BP) regulation of nucleoside metabolic process 0.000000008723 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.00000002486 Informative Direct
Biological Process (BP) regulation of cellular catabolic process 0.000003487 Informative Direct
Biological Process (BP) single organism reproductive process 0.00001245 Informative Direct
Biological Process (BP) positive regulation of hydrolase activity 0.0000082 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) regulation of purine nucleotide metabolic process 0.0000001253 Informative Direct
Biological Process (BP) multicellular organismal reproductive process 0.1292 Informative Inherited
Biological Process (BP) cellular ketone metabolic process 0.001505 Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.402 Informative Inherited
Biological Process (BP) secretion by cell 0.03528 Informative Inherited
Biological Process (BP) sexual reproduction 0.5153 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.2811 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.02221 Informative Inherited
Biological Process (BP) posttranscriptional regulation of gene expression 0.004436 Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.3286 Informative Inherited
Biological Process (BP) hexose metabolic process 0.0534 Informative Inherited
Biological Process (BP) reproductive system development 0.001987 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.01065 Informative Inherited
Biological Process (BP) amino sugar metabolic process 0 Highly Informative Direct
Biological Process (BP) translational initiation 0 Highly Informative Direct
Biological Process (BP) regulation of translation 0.00004852 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.0005371 Highly Informative Direct
Biological Process (BP) gonad development 0.000000143 Highly Informative Direct
Biological Process (BP) response to heat 0.000002857 Highly Informative Direct
Biological Process (BP) response to carbohydrate stimulus 0.000385 Highly Informative Direct
Biological Process (BP) glial cell differentiation 0.000000000000003755 Highly Informative Direct
Biological Process (BP) pentose metabolic process 0.0001934 Highly Informative Direct
Biological Process (BP) ovulation cycle process 0.0000000000107 Highly Informative Direct
Biological Process (BP) regulation of membrane potential 0.0000003637 Highly Informative Direct
Biological Process (BP) positive regulation of GTPase activity 0.0000000002208 Highly Informative Direct
Biological Process (BP) nicotinamide nucleotide metabolic process 0 Highly Informative Direct
Biological Process (BP) development of primary female sexual characteristics 0.0000000002093 Highly Informative Direct
Biological Process (BP) exocytosis 0.001397 Highly Informative Inherited
Biological Process (BP) fertilization 0.005083 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity 0.6255 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.000000529 Moderately Informative Direct
Molecular Function (MF) isomerase activity 0 Moderately Informative Direct
Molecular Function (MF) enzyme regulator activity 0.0000000009416 Moderately Informative Direct
Molecular Function (MF) anion binding 0.07971 Moderately Informative Inherited
Molecular Function (MF) oxidoreductase activity 1 Moderately Informative Inherited
Molecular Function (MF) nucleic acid binding 0.001472 Moderately Informative Inherited
Molecular Function (MF) RNA binding 0.00000000005302 Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 0.0002537 Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity 0 Informative Direct
Molecular Function (MF) GTPase regulator activity 0.00000000000001334 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0.0007878 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.0008467 Informative Direct
Molecular Function (MF) nucleotide binding 0.4075 Informative Inherited
Molecular Function (MF) ligase activity 0.301 Informative Inherited
Molecular Function (MF) guanyl-nucleotide exchange factor activity 0 Highly Informative Direct
Molecular Function (MF) translation factor activity, nucleic acid binding 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.000104 Highly Informative Direct
Molecular Function (MF) intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0 Highly Informative Direct
Molecular Function (MF) deaminase activity 0 Highly Informative Direct
Molecular Function (MF) carboxylic ester hydrolase activity 0.000000000131 Highly Informative Direct
Molecular Function (MF) thiolester hydrolase activity 0.01493 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.0000002434 Least Informative Direct
Cellular Component (CC) protein complex 0.1452 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Ligases1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0Moderately InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0.00000000000001442Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds1Moderately InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c0InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases0.00002533InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.01457InformativeInherited
Enzyme Commission (EC)In other compounds0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)genital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)male organism0Least InformativeDirect
Xenopus ANatomical entity (XAN)viscus0Least InformativeDirect
Xenopus ANatomical entity (XAN)gonad0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.000176Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds0Moderately InformativeDirect
Enzyme Commission (EC)Isomerases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on the CH-OH group of donors1Moderately InformativeInherited
Enzyme Commission (EC)Carbon-carbon lyases1Moderately InformativeInherited
Enzyme Commission (EC)Ligases1Moderately InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0InformativeDirect
Enzyme Commission (EC)Carboxylic ester hydrolases0.000000000000008035InformativeDirect
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor1InformativeInherited
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related compounds0Highly InformativeDirect
Enzyme Commission (EC)Cyclo-ligases0.0001102Highly InformativeDirect
Enzyme Commission (EC)Oxo-acid-lyases0.3596Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processMethionine biosynthesis0Highly InformativeDirect
Post-translational modificationHydrolase0.000002164Least InformativeDirect
Post-translational modificationIsomerase0Moderately InformativeDirect
Post-translational modificationRepressor0.000002682Moderately InformativeDirect
Post-translational modificationInitiation factor0.00000001762InformativeDirect

Document: KW annotation of SCOP domains

UniProtKB UniPathway (UP)

(show details)
UP termFDR (all)SDUP levelAnnotation (direct or inherited)
UniPathway (UP)carbohydrate metabolism0Least InformativeDirect
UniPathway (UP)amino-acid metabolism0.2581Least InformativeInherited
UniPathway (UP)aromatic compound metabolism1Least InformativeInherited
UniPathway (UP)lipid metabolism1Least InformativeInherited
UniPathway (UP)carbohydrate degradation0Moderately InformativeDirect
UniPathway (UP)amine and polyamine metabolism0Moderately InformativeDirect
UniPathway (UP)proteinogenic amino-acid biosynthesis8.993e-16Moderately InformativeDirect
UniPathway (UP)fatty acid metabolism1Moderately InformativeInherited
UniPathway (UP)amino-sugar metabolism0InformativeDirect
UniPathway (UP)amine and polyamine degradation0InformativeDirect
UniPathway (UP)L-methionine biosynthesis0InformativeDirect
UniPathway (UP)pentose phosphate pathway0Highly InformativeDirect
UniPathway (UP)N-acetylneuraminate degradation0Highly InformativeDirect
UniPathway (UP)L-methionine biosynthesis via salvage pathway0Highly InformativeDirect
UniPathway (UP)beta-ketoadipate pathway0.0000004692Highly InformativeDirect
UniPathway (UP)ketone degradation1Highly InformativeInherited

Document: UP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 32 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a NagB/RpiA/CoA transferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 32 hidden Markov models representing the NagB/RpiA/CoA transferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · UniProtKB UniPathway (UP) · Internal database links ]