SUPERFAMILY 1.75 HMM library and genome assignments server

Yeast Phenotype (YP): metabolism and growth

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Root: YP Hierarchy (yeast phenotype from Ascomycete phenotype ontology)

Shortest distance to current term (+ for parents, - for children) YP term [YP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   observable [APO:0000017] <7>
0:   metabolism and growth [APO:0000094] <13>(59|56) (59|21|3)
- 1:   nutrient utilization [APO:0000096] <9>(21|19) (21|6|0)
- 1:   vegetative growth [APO:0000106] <3>(13|14) (13|7|0)
- 1:   anaerobic metabolism [APO:0000210] <1>(0|0) (0|0|0)
- 1:   RNA accumulation [APO:0000224](2|0) (2|1|0)
- 1:   RNA modification [APO:0000271](2|1) (2|0|0)
- 1:   chemical compound accumulation [APO:0000095](6|6) (6|2|0)
- 1:   chemical compound excretion [APO:0000222](1|2) (1|0|0)
- 1:   protein activity [APO:0000022](0|0) (0|0|0)
- 1:   protein/peptide accumulation [APO:0000149](2|3) (2|1|0)
- 1:   protein/peptide distribution [APO:0000209](2|3) (2|0|0)
- 1:   protein/peptide modification [APO:0000131](4|4) (4|0|0)
- 1:   redox state [APO:0000218](0|0) (0|0|0)
- 1:   secondary metabolite production [APO:0000292](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RNase III domain-like0Direct
Subtilisin-like0Direct
The spindle assembly checkpoint protein mad20Direct
Ribosomal protein L140Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
SAICAR synthase-like0Direct
Ammonium transporter0Direct
Cupredoxins0Direct
SAP domain0Direct
Prefoldin0Direct
tRNA-binding arm0Direct
4'-phosphopantetheinyl transferase0Direct
PLP-binding barrel0Direct
Endosomal sorting complex assembly domain0Direct
HRDC-like0Direct
GYF domain0Direct
Seven-hairpin glycosidases0Direct
Ras GEF0Direct
Chromo domain-like0Direct
HMA, heavy metal-associated domain0Direct
Nucleotide-binding domain0Direct
Ribosomal protein L130Direct
Ribosomal protein L60Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Ribosomal L11/L12e N-terminal domain0Direct
PAP/OAS1 substrate-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
SAM/Pointed domain0Direct
S13-like H2TH domain0Direct
Phospholipase D/nuclease0Direct
CheY-like0Direct
FtsH protease domain-like0Direct
F1F0 ATP synthase subunit C0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Cytochrome c0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Ribosomal protein L11, C-terminal domain0Direct
Actin depolymerizing proteins0Direct
Mitochondrial carrier0.0005038Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0.009924Inherited
EF-G C-terminal domain-like0.0641Inherited
Bromodomain0.09579Inherited
PreATP-grasp domain0.09579Inherited
UBA-like0.1231Inherited
TK C-terminal domain-like0.1516Inherited
Protein kinase-like (PK-like)0.2249Inherited
Glutathione synthetase ATP-binding domain-like0.2694Inherited
Pseudouridine synthase0.2705Inherited
FYVE/PHD zinc finger0.3008Inherited
Actin-like ATPase domain0.3127Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.3221Inherited
WW domain0.3584Inherited
Nucleotidyltransferase0.3584Inherited
Class II aaRS and biotin synthetases0.4017Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.4733Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.5527Inherited
MFS general substrate transporter0.6722Inherited
NAD(P)-binding Rossmann-fold domains0.7763Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ribosomal protein L130Direct
Tetrahydrofolate dehydrogenase/cyclohydrolase0Direct
SAP domain0Direct
FabD-like0Direct
Ras GEF0Direct
Ribosomal L11/L12e N-terminal domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Vacuolar sorting protein domain0Direct
C-terminal domain of ribosomal protein L20Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L140Direct
Ribosomal protein S130Direct
FAD-linked oxidases, N-terminal domain0Direct
RecA protein-like (ATPase-domain)0Direct
DJ-1/PfpI0Direct
GYF domain0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Ribosomal protein L11, C-terminal domain0Direct
SAM (sterile alpha motif) domain0Direct
Cofilin-like0Direct
NAD kinase-like0Direct
Prefoldin0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Multidomain cupredoxins0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Pseudouridine synthase I TruA0Direct
Subtilases0Direct
La domain0Direct
Ran-binding domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
RNB domain-like0Direct
Tryptophan biosynthesis enzymes0Direct
FtsH protease domain-like0Direct
Ammonium transporter0Direct
HMA, heavy metal-associated domain0Direct
Phosphate binding protein-like0Direct
Ribosomal protein L60Direct
CheY-related0Direct
Glucose 6-phosphate dehydrogenase-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0.008252Inherited
EF-G/eEF-2 domains III and V0.05331Inherited
Bromodomain0.08204Inherited
UBC-related0.09879Inherited
PX domain0.09879Inherited
BC N-terminal domain-like0.1183Inherited
BC ATP-binding domain-like0.1183Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.1296Inherited
Clathrin adaptor core protein0.1687Inherited
WW domain0.3276Inherited
Class I glutamine amidotransferases (GAT)0.3973Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.4043Inherited
Protein kinases, catalytic subunit0.4294Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.5313Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.8514Inherited
Extended AAA-ATPase domain0.9592Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SAP domain0Direct
tRNA-binding arm0Direct
F1F0 ATP synthase subunit C0Direct
HRDC-like0Direct
HMA, heavy metal-associated domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GYF domain0Direct
Actin depolymerizing proteins0Direct
PLP-binding barrel0Direct
S13-like H2TH domain0Direct
Ribosomal L11/L12e N-terminal domain0Direct
Seven-hairpin glycosidases0Direct
Cupredoxins0Direct
Ammonium transporter0Direct
Ribosomal protein L60Direct
Subtilisin-like0Direct
SAICAR synthase-like0Direct
Ribosomal protein L140Direct
PAP/OAS1 substrate-binding domain0Direct
Ribosomal protein L11, C-terminal domain0Direct
Nucleotide-binding domain0Direct
SAM/Pointed domain0Direct
Endosomal sorting complex assembly domain0Direct
Phospholipase D/nuclease0Direct
Ras GEF0Direct
RNase III domain-like0Direct
Prefoldin0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
The spindle assembly checkpoint protein mad20Direct
FtsH protease domain-like0Direct
Chromo domain-like0Direct
4'-phosphopantetheinyl transferase0Direct
Ribosomal protein L130Direct
Cytochrome c0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
HSP40/DnaJ peptide-binding domain0Direct
CheY-like0Direct
Mitochondrial carrier0.0004331Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0.008765Inherited
EF-G C-terminal domain-like0.05885Inherited
Bromodomain0.0888Inherited
PreATP-grasp domain0.0888Inherited
UBA-like0.1146Inherited
TK C-terminal domain-like0.142Inherited
Protein kinase-like (PK-like)0.213Inherited
Glutathione synthetase ATP-binding domain-like0.2571Inherited
Pseudouridine synthase0.2581Inherited
FYVE/PHD zinc finger0.2881Inherited
Actin-like ATPase domain0.2998Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.3089Inherited
Nucleotidyltransferase0.3457Inherited
WW domain0.3457Inherited
Class II aaRS and biotin synthetases0.3888Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.461Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.5408Inherited
MFS general substrate transporter0.6621Inherited
NAD(P)-binding Rossmann-fold domains0.7688Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56053,56053
  • 56053 - Ribosomal protein L6
  • 56053 - Ribosomal protein L6
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    54747,46906
  • 54747 - Ribosomal L11/L12e N-terminal domain
  • 46906 - Ribosomal protein L11, C-terminal domain
  • 0Direct
    50249,50104
  • 50249 - Nucleic acid-binding proteins
  • 50104 - Translation proteins SH3-like domain
  • 0Direct
    49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57701,57959
  • 57701 - Zn2/Cys6 DNA-binding domain
  • 57959 - Leucine zipper domain
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0.008765Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.1279Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.3457Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.4363Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49503,49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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