SUPERFAMILY 1.75 HMM library and genome assignments server

Xenopus ANatomical entity (XAN): anatomical region

(show info)

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Root: XA Hierarchy (Xenopus anatomy and development from Xenbase frog anatomy ontology)

Shortest distance to current term (+ for parents, - for children) XA term [XA ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   anatomical structure [XAO:0003000] <14>(473|579) (473|263|86)
+ 1:   whole organism [XAO:0003004] <15>(473|579) (473|263|86)
+ 1:   Xenopus anatomical entity [XAO:0000000] <9>
0:   anatomical region [XAO:0003186] <23>(449|559) (449|261|84)
- 1:   pharyngeal region [XAO:0004261] <6>(10|12) (10|4|1)
- 1:   intersomitic region [XAO:0004074] <4>(6|7) (6|1|0)
- 1:   head region [XAO:0000040] <3>(223|308) (223|150|52)
- 1:   joint region [XAO:0004313] <2>(0|0) (0|0|0)
- 1:   tail region [XAO:0000087] <2>(22|33) (22|11|2)
- 1:   interdigital region [XAO:0004316] <1>(0|0) (0|0|0)
- 1:   retinal progenitor cell region [XAO:0004388] <1>(0|0) (0|0|0)
- 1:   retinal stem cell region [XAO:0004387] <1>(0|0) (0|0|0)
- 1:   trunk region [XAO:0000054] <1>(345|451) (346|195|65)
- 1:   vegetal hemisphere [XAO:0000280] <1>(2|2) (2|1|0)
- 1:   animal hemisphere [XAO:0000202](2|3) (3|3|1)
- 1:   animal pole [XAO:0004088](3|4) (3|4|1)
- 1:   central retina [XAO:0004424](0|0) (0|0|0)
- 1:   forelimb region [XAO:0000080](0|0) (0|0|0)
- 1:   hindlimb region [XAO:0000081](0|0) (0|0|0)
- 1:   marginal zone (sensu neural) [XAO:0000309](0|0) (0|0|0)
- 1:   optic field [XAO:0004090](6|4) (6|1|0)
- 1:   periocular region [XAO:0004089](1|2) (1|0|0)
- 1:   periotic region [XAO:0004474](0|0) (0|0|0)
- 1:   peripheral retina [XAO:0004458](0|0) (0|0|0)
- 1:   proximal tubule branch [XAO:0004520](0|0) (0|0|0)
- 1:   vegetal pole [XAO:0004113](0|0) (0|0|0)
- 1:   ventricular zone [XAO:0000021](2|2) (2|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Tim10-like0Direct
Cytidine deaminase-like0Direct
B-box zinc-binding domain0Direct
ArfGap/RecO-like zinc finger0Direct
Di-copper centre-containing domain0Direct
BSD domain-like0Direct
Lipoxigenase0Direct
RNase III domain-like0Direct
Rudiment single hybrid motif0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
Phosphoglucomutase, first 3 domains0Direct
Integrin alpha N-terminal domain0Direct
MIR domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Subtilisin-like0Direct
TK C-terminal domain-like0Direct
Globin-like0Direct
Formin homology 2 domain (FH2 domain)0Direct
Rap/Ran-GAP0Direct
TATA-box binding protein-like0Direct
Transcription factor IIA (TFIIA), beta-barrel domain0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
EF-G C-terminal domain-like0Direct
Transducin (alpha subunit), insertion domain0Direct
Cadherin-like0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Actin-like ATPase domain0Direct
His-Me finger endonucleases0Direct
E set domains0Direct
LDL receptor-like module0Direct
SCP-like0Direct
LuxS/MPP-like metallohydrolase0Direct
Sm-like ribonucleoproteins0Direct
Oxysterol-binding protein-like0Direct
ATP-dependent DNA ligase DNA-binding domain0Direct
Acyl-CoA dehydrogenase NM domain-like0Direct
NHL repeat0Direct
RCC1/BLIP-II0Direct
USP8 N-terminal domain-like0Direct
Snake toxin-like0Direct
Moesin tail domain0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Cupredoxins0Direct
Tubby C-terminal domain-like0Direct
Carbohydrate phosphatase0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
CBS-domain pair0Direct
SMAD/FHA domain0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Prefoldin0Direct
SAP domain0Direct
FabD/lysophospholipase-like0Direct
Composite domain of metallo-dependent hydrolases0Direct
Pseudouridine synthase0Direct
NAP-like0Direct
Metallo-dependent phosphatases0Direct
Eferin C-derminal domain-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Bromodomain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Somatomedin B domain0Direct
PLP-binding barrel0Direct
RuvA domain 2-like0Direct
FnI-like domain0Direct
HCP-like0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
S15/NS1 RNA-binding domain0Direct
Trefoil0Direct
ADP-ribosylation0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
ARID-like0Direct
Protease propeptides/inhibitors0Direct
Lipocalins0Direct
Proton glutamate symport protein0Direct
Intermediate filament protein, coiled coil region0Direct
PriA/YqbF domain0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
Second domain of FERM0Direct
Ribokinase-like0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
DNA/RNA polymerases0Direct
HD-domain/PDEase-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Creatinase/prolidase N-terminal domain0Direct
L27 domain0Direct
HRDC-like0Direct
Chaperone J-domain0Direct
Spectrin repeat0Direct
DHS-like NAD/FAD-binding domain0Direct
Zn-binding ribosomal proteins0Direct
vWA-like0Direct
Terpenoid synthases0Direct
VPS9 domain0Direct
PABC (PABP) domain0Direct
14-3-3 protein0Direct
TRAF domain-like0Direct
TNF receptor-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Hect, E3 ligase catalytic domain0Direct
Hemopexin-like domain0Direct
Complement control module/SCR domain0Direct
UBC-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Sec1/munc18-like (SM) proteins0Direct
Class II aaRS and biotin synthetases0Direct
Class II aaRS ABD-related0Direct
L30e-like0Direct
Formyltransferase0Direct
Clavaminate synthase-like0Direct
DNA-glycosylase0Direct
JAB1/MPN domain0Direct
HIT/MYND zinc finger-like0Direct
Voltage-gated potassium channels0Direct
PapD-like0Direct
CoA-dependent acyltransferases0Direct
Tricorn protease domain 20Direct
Tudor/PWWP/MBT0Direct
Transcription factor IIA (TFIIA), alpha-helical domain0Direct
Mannose 6-phosphate receptor domain0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
Elongation factor TFIIS domain 20Direct
Sec7 domain0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
GLA-domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
PDZ domain-like0Direct
Nucleoside diphosphate kinase, NDK0Direct
Ribonuclease PH domain 2-like0Direct
Enolase C-terminal domain-like0Direct
KRAB domain (Kruppel-associated box)0Direct
PA domain0Direct
Lamin A/C globular tail domain0Direct
AN1-like Zinc finger0Direct
GST C-terminal domain-like0Direct
Restriction endonuclease-like0Direct
Troponin coil-coiled subunits0Direct
Tubulin C-terminal domain-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
SRCR-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Single hybrid motif0Direct
Calcium ATPase, transmembrane domain M0Direct
Alpha-macroglobulin receptor domain0Direct
PRTase-like0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
Glycosyl hydrolase domain0Direct
GAT-like domain0Direct
Fibronectin type III0Direct
Cullin homology domain0Direct
ThrRS/AlaRS common domain0Direct
eIF1-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Cytochrome b5-like heme/steroid binding domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Hormone receptor domain0Direct
Fibrinogen C-terminal domain-like0Direct
Zinc beta-ribbon0Direct
Nucleotide cyclase0Direct
MHC antigen-recognition domain0Direct
ACT-like0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Nop domain0Direct
Myosin rod fragments0Direct
PAP/OAS1 substrate-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
SAM/Pointed domain0Direct
BRK domain-like0Direct
Frizzled cysteine-rich domain0Direct
SNARE-like0Direct
Translation proteins0Direct
PKD domain0Direct
Macro domain-like0Direct
Insulin-like0Direct
ABC transporter transmembrane region0Direct
GINS helical bundle-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
SRF-like0Direct
Acid proteases0Direct
p53-like transcription factors0Direct
Ran binding protein zinc finger-like0Direct
BAG domain0Direct
Translational machinery components0Direct
F1F0 ATP synthase subunit C0Direct
SNARE fusion complex0Direct
NAD(P)-linked oxidoreductase0Direct
Aldolase0Direct
UBA-like0Direct
gamma-Crystallin-like0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
GAF domain-like0Direct
Arginase/deacetylase0Direct
Kelch motif0Direct
TGS-like0Direct
Adenine nucleotide alpha hydrolases-like0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Sec63 N-terminal domain-like0Direct
Cu,Zn superoxide dismutase-like0Direct
BTG domain-like0Direct
C-terminal domain of adenylylcyclase associated protein0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Succinyl-CoA synthetase domains0Direct
Polo-box domain0Direct
Sema domain0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Actin-crosslinking proteins0Direct
BPTI-like0Direct
Nucleoplasmin-like core domain0Direct
Hedgehog/DD-peptidase0Direct
Annexin0Direct
Acyl-CoA binding protein0Direct
Nucleotidyltransferase0Direct
Plexin repeat0Direct
Cation efflux protein cytoplasmic domain-like0Direct
THUMP domain-like0Direct
Outer arm dynein light chain 10Direct
Enolase N-terminal domain-like0Direct
Caspase-like0Direct
2Fe-2S ferredoxin-like0Direct
Cation efflux protein transmembrane domain-like0Direct
Zn-dependent exopeptidases0Direct
Ribonuclease H-like0Direct
PR-1-like0Direct
Galactose oxidase, central domain0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Nucleic acid-binding proteins0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Galactose-binding domain-like0Direct
Tropomyosin0Direct
SET domain0Direct
LeuD/IlvD-like0Direct
PAZ domain0Direct
WW domain0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
Integrin domains0Direct
Galactose mutarotase-like0Direct
TIMP-like0Direct
HIT-like0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Clathrin adaptor appendage domain0Direct
LDH C-terminal domain-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
SOCS box-like0Direct
C-type lectin-like0Direct
SNF-like0Direct
TSP-1 type 1 repeat0Direct
L-aspartase-like0Direct
Class I glutamine amidotransferase-like0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Nucleotidylyl transferase0Direct
GroEL-intermediate domain like0Direct
Stathmin0Direct
Cystatin/monellin0Direct
Creatinase/aminopeptidase0Direct
Fibrinogen coiled-coil and central regions0Direct
SAICAR synthase-like0Direct
Metallo-hydrolase/oxidoreductase0Direct
Ammonium transporter0Direct
Serpins0Direct
VHP, Villin headpiece domain0Direct
Kazal-type serine protease inhibitors0Direct
ARM repeat0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
DBL homology domain (DH-domain)0Direct
Proteasome activator0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Aconitase iron-sulfur domain0Direct
Nudix0Direct
Alanine racemase C-terminal domain-like0Direct
DUSP-like0Direct
Glutathione synthetase ATP-binding domain-like0Direct
SMAD MH1 domain0Direct
PP2C-like0Direct
Periplasmic binding protein-like I0Direct
Glycoside hydrolase/deacetylase0Direct
DNA clamp0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Mib/herc2 domain-like0Direct
Acyl-CoA dehydrogenase C-terminal domain-like0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
FYVE/PHD zinc finger0Direct
NAD kinase/diacylglycerol kinase-like0Direct
Tetraspanin0Direct
ClpP/crotonase0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
DPP6 N-terminal domain-like0Direct
NAD(P)-binding Rossmann-fold domains0Direct
PLP-dependent transferases0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
Cyclin-like0Direct
Apolipoprotein A-I0Direct
Ferritin-like0Direct
Endosomal sorting complex assembly domain0Direct
Calcium ATPase, transduction domain A0Direct
FAD/NAD(P)-binding domain0Direct
LEM domain0Direct
KA1-like0Direct
Carbonic anhydrase0Direct
YWTD domain0Direct
PLC-like phosphodiesterases0Direct
GroEL apical domain-like0Direct
AraD/HMP-PK domain-like0Direct
Surp module (SWAP domain)0Direct
ALDH-like0Direct
Glutamine synthetase/guanido kinase0Direct
Seven-hairpin glycosidases0Direct
MIT domain0Direct
E2F-DP heterodimerization region0Direct
Phosphoglycerate mutase-like0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
WD40 repeat-like0Direct
Nicotinic receptor ligand binding domain-like0Direct
"Winged helix" DNA-binding domain0Direct
Smc hinge domain0Direct
Families 57/38 glycoside transferase middle domain0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
DNase I-like0Direct
DNA-binding domain0Direct
Ras GEF0Direct
GHMP Kinase, C-terminal domain0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
Mitochondrial carrier0Direct
PX domain0Direct
Riboflavin synthase domain-like0Direct
Chromo domain-like0Direct
post-AAA+ oligomerization domain-like0Direct
beta-sandwich domain of Sec23/240Direct
Translation proteins SH3-like domain0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0Direct
Acetyl-CoA synthetase-like0Direct
F-box domain0Direct
SWIB/MDM2 domain0Direct
Rhomboid-like0Direct
Guanido kinase N-terminal domain0Direct
RmlC-like cupins0Direct
Calponin-homology domain, CH-domain0Direct
Radical SAM enzymes0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Carbon-nitrogen hydrolase0Direct
Ribosomal protein S5 domain 2-like0Direct
Flavoproteins0Direct
Dimeric alpha+beta barrel0Direct
Bcl-2 inhibitors of programmed cell death0Direct
3-carboxy-cis,cis-mucoante lactonizing enzyme0Direct
4Fe-4S ferredoxins0Direct
Bet v1-like0Direct
Pentein0Direct
FAS1 domain0Direct
t-snare proteins0Direct
PYP-like sensor domain (PAS domain)0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Mob1/phocein0Direct
Plakin repeat0Direct
DLC0Direct
dsRNA-binding domain-like0Direct
FAD-linked reductases, C-terminal domain0Direct
Uracil-DNA glycosylase-like0Direct
FMN-linked oxidoreductases0Direct
A heparin-binding domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Clc chloride channel0Direct
occludin/ELL-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
ENTH/VHS domain0Direct
RUN domain-like0Direct
Alkaline phosphatase-like0Direct
MAPEG domain-like0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
TSP type-3 repeat0Direct
GroES-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
HSP90 C-terminal domain0Direct
NagB/RpiA/CoA transferase-like0Direct
Calcium-dependent phosphotriesterase0Direct
Periplasmic binding protein-like II0Direct
Ricin B-like lectins0Direct
Carboxypeptidase regulatory domain-like0Direct
Phospholipase D/nuclease0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Ribosomal proteins L15p and L18e0Direct
Amidase signature (AS) enzymes0Direct
GroEL equatorial domain-like0Direct
PGBD-like0Direct
alpha-catenin/vinculin-like0Direct
PUA domain-like0Direct
Growth factor receptor domain0Direct
Six-hairpin glycosidases0Direct
Thyroglobulin type-1 domain0Direct
DNA polymerase beta, N-terminal domain-like0Direct
PreATP-grasp domain0Direct
GTPase activation domain, GAP0Direct
Connexin430Direct
Cysteine proteinases0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Pectin lyase-like0Direct
Cysteine alpha-hairpin motif0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
Putative DNA-binding domain0Direct
Cyclophilin-like0Direct
Thiolase-like0Direct
Cap-Gly domain0Direct
Synuclein0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
R3H domain0Direct
eIF4e-like0Direct
Band 7/SPFH domain0Direct
WWE domain0Direct
FF domain0Direct
Ribosomal L27 protein-like0Direct
Roadblock/LC7 domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
Calpain large subunit, middle domain (domain III)0Direct
NTF2-like0Direct
CAD & PB1 domains0Direct
SpoIIaa-like0Direct
BRCT domain0Direct
Metallo-dependent hydrolases0Direct
Cullin repeat-like0Direct
Mss4-like0Direct
Protein kinase-like (PK-like)0.04669Inherited
PH domain-like0.1664Inherited
RNA-binding domain, RBD0.2331Inherited
RING/U-box0.2695Inherited
Ubiquitin-like0.4535Inherited
Thioredoxin-like0.5698Inherited
EGF/Laminin0.6528Inherited
EF-hand0.7019Inherited
Trypsin-like serine proteases0.7605Inherited
Immunoglobulin0.7806Inherited
HMG-box0.8072Inherited
SH2 domain0.8244Inherited
Leucine zipper domain0.8931Inherited
Concanavalin A-like lectins/glucanases0.9349Inherited
Acyl-CoA N-acyltransferases (Nat)0.9455Inherited
CCCH zinc finger0.9455Inherited
Cytokine1Inherited
lambda repressor-like DNA-binding domains1Inherited
Homeodomain-like1Inherited
Orange domain-like1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Cystine-knot cytokines1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Mammalian PLC0Direct
C-terminal domain of adenylylcyclase associated protein0Direct
GAF domain0Direct
Class I glutamine amidotransferases (GAT)0Direct
4HBT-like0Direct
DnaQ-like 3'-5' exonuclease0Direct
Rel/Dorsal transcription factors, DNA-binding domain0Direct
UBX domain0Direct
Bcl-2 inhibitors of programmed cell death0Direct
Caspase catalytic domain0Direct
Bacterial dinuclear zinc exopeptidases0Direct
GAT domain0Direct
Chromo barrel domain0Direct
Armadillo repeat0Direct
Biotin dependent carboxylase carboxyltransferase domain0Direct
CUE domain0Direct
Cystathionine synthase-like0Direct
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0Direct
Extended AAA-ATPase domain0Direct
TSP type-3 repeat0Direct
SOCS box-like0Direct
Glutathione S-transferase (GST), N-terminal domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
Fibrinogen coiled-coil and central regions0Direct
Steroid-binding domain0Direct
Nicotinic receptor ligand binding domain-like0Direct
Cofactor-dependent phosphoglycerate mutase0Direct
Methyl-CpG-binding domain, MBD0Direct
Surp module (SWAP domain)0Direct
Fibronectin type II module0Direct
ABC transporter transmembrane region0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
MutT-like0Direct
Stathmin0Direct
Calcium ATPase, transduction domain A0Direct
Arginase-like amidino hydrolases0Direct
DPP6 N-terminal domain-like0Direct
RPR domain (SMART 00582 )0Direct
DPP6 catalytic domain-like0Direct
Outer arm dynein light chain 10Direct
Dachshund-homology domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
A heparin-binding domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Proprotein convertase P-domain0Direct
Motor proteins0Direct
Hect, E3 ligase catalytic domain0Direct
Sema domain0Direct
EF-hand modules in multidomain proteins0Direct
Tyrosine-dependent oxidoreductases0Direct
Ras-binding domain, RBD0Direct
CAT-like0Direct
GS domain0Direct
B56-like0Direct
PR-1-like0Direct
Pancreatic lipase, N-terminal domain0Direct
Enolase N-terminal domain-like0Direct
Pyridoxal-dependent decarboxylase0Direct
DEATH domain, DD0Direct
Tetraspanin0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
NAP-like0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Interferon regulatory factor0Direct
Meta-cation ATPase, catalytic domain P0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Kinase associated domain 1, KA10Direct
L-aminoacid/polyamine oxidase0Direct
Spectrin repeat0Direct
TSP-1 type 1 repeat0Direct
DNase I-like0Direct
Cyclophilin (peptidylprolyl isomerase)0Direct
Ribosomal protein L30Direct
Band 7/SPFH domain0Direct
UBA domain0Direct
Single strand DNA-binding domain, SSB0Direct
Phosphoribosyltransferases (PRTases)0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
MIF4G domain-like0Direct
Complement components0Direct
RING finger domain, C3HC40Direct
L30e/L7ae ribosomal proteins0Direct
Lactate & malate dehydrogenases, C-terminal domain0Direct
Hsp90 middle domain0Direct
ALDH-like0Direct
Cullin homology domain0Direct
HAT/Suf repeat0Direct
Acetyl-CoA synthetase-like0Direct
Calpain large subunit, middle domain (domain III)0Direct
Creatinase/aminopeptidase0Direct
Aconitase iron-sulfur domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
NHL repeat0Direct
PHD domain0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0Direct
alpha-mannosidase, domain 20Direct
Plexin repeat0Direct
PAPS sulfotransferase0Direct
Pointed domain0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
SWIB/MDM2 domain0Direct
Ovomucoid domain III-like0Direct
LeuD-like0Direct
5' nucleotidase-like0Direct
Fibrinogen C-terminal domain-like0Direct
Clc chloride channel0Direct
Serpins0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0Direct
SAM (sterile alpha motif) domain0Direct
CAD domain0Direct
Histone deacetylase, HDAC0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Inositol polyphosphate kinase (IPK)0Direct
Crotonase-like0Direct
Penta-EF-hand proteins0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
Hydantoinase (dihydropyrimidinase)0Direct
R3H domain0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
Alcohol dehydrogenase-like, C-terminal domain0Direct
Cytochrome b50Direct
Ran binding protein zinc finger-like0Direct
Malic enzyme N-domain0Direct
FHA domain0Direct
Plakophilin 1 helical region0Direct
RUN domain0Direct
PP2C-like0Direct
Integrin domains0Direct
Phoshatidylinositol transfer protein, PITP0Direct
SMAD MH1 domain0Direct
Glutathione S-transferase (GST), C-terminal domain0Direct
Ribosomal protein L18 and S110Direct
Translational machinery components0Direct
alpha-mannosidase0Direct
VHP, Villin headpiece domain0Direct
HkH motif-containing C2H2 finger0Direct
AN1-like Zinc finger0Direct
Amidase signature (AS) enzymes0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Nuclear receptor coactivator interlocking domain0Direct
UDPGT-like0Direct
ABC transporter ATPase domain-like0Direct
HCDH C-domain-like0Direct
Leukotriene A4 hydrolase catalytic domain0Direct
Mib/herc2 domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
GLA-domain0Direct
TRAPP components0Direct
Pancreatic carboxypeptidases0Direct
Thiolase-related0Direct
Hypoxia-inducible factor HIF ihhibitor (FIH1)0Direct
Serine carboxypeptidase-like0Direct
Retinol binding protein-like0Direct
Occludin/ELL domain0Direct
FF domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
BSD domain0Direct
LEM domain0Direct
Smc hinge domain0Direct
PDI-like0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
A20-like zinc finger0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
C-type lectin domain0Direct
Pleckstrin-homology domain (PH domain)0Direct
UDP-glucose pyrophosphorylase0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Formyltransferase0Direct
NIPSNAP0Direct
Globins0Direct
GABARAP-like0Direct
Myb/SANT domain0Direct
Papain-like0Direct
Guanido kinase N-terminal domain0Direct
t-snare proteins0Direct
Variant RING domain0Direct
SPRY domain0Direct
Link domain0Direct
L-arabinose binding protein-like0Direct
Subtilases0Direct
Platelet-derived growth factor-like0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
Ferredoxin reductase FAD-binding domain-like0Direct
Hemopexin-like domain0Direct
Eps15 homology domain (EH domain)0Direct
Macro domain0Direct
BC N-terminal domain-like0Direct
Intermediate filament protein, coiled coil region0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Cation efflux protein transmembrane domain-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Sir2 family of transcriptional regulators0Direct
Arrestin/Vps26-like0Direct
MAM domain0Direct
HEAT repeat0Direct
Polo-box duplicated region0Direct
DNA gyrase/MutL, second domain0Direct
Nucleoplasmin-like core domain0Direct
PUA domain0Direct
a tRNA synthase domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
RWD domain0Direct
Glutathione peroxidase-like0Direct
ARID domain0Direct
GHMP Kinase, N-terminal domain0Direct
Pepsin-like0Direct
Cap-Gly domain0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
PWWP domain0Direct
DLC0Direct
I set domains0Direct
Exostosin0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Guanido kinase catalytic domain0Direct
MSP-like0Direct
DNA polymerase I0Direct
MIR domain0Direct
Type II chitinase0Direct
Arylsulfatase0Direct
Anticodon-binding domain0Direct
Cold shock DNA-binding domain-like0Direct
Adenosine/AMP deaminase0Direct
Epoxide hydrolase0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Tubulin, GTPase domain0Direct
LDH N-terminal domain-like0Direct
Alanine racemase-like, N-terminal domain0Direct
MAPEG domain0Direct
Crystallins/Ca-binding development proteins0Direct
ENTH domain0Direct
Tim10/DDP0Direct
SH3BGR (SH3-binding, glutamic acid-rich protein-like)0Direct
Protein serine/threonine phosphatase0Direct
Bromodomain0Direct
Synuclein0Direct
TATA-box binding protein (TBP), C-terminal domain0Direct
Chromo domain0Direct
Apolipoprotein A-I0Direct
NagB-like0Direct
Cullin repeat0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
PX domain0Direct
Proteasome activator0Direct
Neurotrophin0Direct
Carboxypeptidase regulatory domain0Direct
NOL1/NOP2/sun0Direct
Mitochondrial carrier0Direct
B-box zinc-binding domain0Direct
Ricin B-like0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
FAD-linked reductases, N-terminal domain0Direct
Glycosyl transferases group 10Direct
p120GAP domain-like0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
DUSP, domain in ubiquitin-specific proteases0Direct
Kelch motif0Direct
Phosphate binding protein-like0Direct
Connexin430Direct
Nucleoside diphosphate kinase, NDK0Direct
Internalin LRR domain0Direct
Growth factor receptor domain0Direct
Chaperone J-domain0Direct
USP8 N-terminal domain-like0Direct
Ribonuclease PH domain 1-like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Mob1/phocein0Direct
14-3-3 protein0Direct
Sterol carrier protein, SCP0Direct
ets domain0Direct
Transcriptional factor tubby, C-terminal domain0Direct
Annexin0Direct
Oxysterol-binding protein0Direct
Interferon regulatory factor 3 (IRF3), transactivation domain0Direct
Third domain of FERM0Direct
Insulin-like0Direct
SAP domain0Direct
Carboxylesterase/thioesterase 10Direct
Cyclin0Direct
PABC (PABP) domain0Direct
Cadherin0Direct
WW domain0Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0Direct
Clathrin adaptor core protein0Direct
Pancreatic carboxypeptidase, activation domain0Direct
Fibronectin type III0Direct
Ribosomal proteins L15p and L18e0Direct
Dual specificity phosphatase-like0Direct
Regulator of chromosome condensation RCC10Direct
MBT repeat0Direct
Glycerol kinase0Direct
VPS9 domain0Direct
Moesin tail domain0Direct
Clathrin adaptor appendage, alpha and beta chain-specific domain0Direct
Autophagin-like0Direct
Small Kunitz-type inhibitors & BPTI-like toxins0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Translation initiation factor eIF4e0Direct
Sec1/munc18-like (SM) proteins0Direct
Ras GEF0Direct
FMN-linked oxidoreductases0Direct
Phosphoglucomutase, first 3 domains0Direct
1,3-glucuronyltransferase0Direct
Protein prenyltransferases0Direct
Acetylcholinesterase-like0Direct
Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain0Direct
Forkhead DNA-binding domain0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Cell cycle transcription factor e2f-dp0Direct
First domain of FERM0Direct
ZZ domain0Direct
Phosphoglucomutase, C-terminal domain0Direct
T-box0Direct
VHS domain0Direct
U-box0Direct
Second domain of FERM0Direct
FAD/NAD-linked reductases, N-terminal and central domains0Direct
Class II glutamine amidotransferases0Direct
RuBisCo LSMT catalytic domain0Direct
Lectin leg-like0Direct
Pseudouridine synthase II TruB0Direct
LDL receptor-like module0Direct
Enabled/VASP homology 1 domain (EVH1 domain)0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
Myotubularin-like phosphatases0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Noggin0Direct
Ubiquitin-related0Direct
gamma-adaptin C-terminal appendage domain-like0Direct
Erythroid transcription factor GATA-10Direct
Choline/Carnitine O-acyltransferase0Direct
Trefoil0Direct
AraD-like aldolase/epimerase0Direct
Neurolysin-like0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
RecA protein-like (ATPase-domain)0Direct
S-adenosylhomocystein hydrolase0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
DNA gyrase/MutL, N-terminal domain0Direct
LIM domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
DNA polymerase beta, N-terminal domain-like0Direct
Transducin (alpha subunit), insertion domain0Direct
Hexokinase0Direct
Voltage-gated potassium channels0Direct
IMD domain0Direct
BAR domain0Direct
Arginine methyltransferase0Direct
TNF receptor-like0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
Carbonic anhydrase0Direct
DNA ligase/mRNA capping enzyme postcatalytic domain0Direct
Synaptotagmin-like (S variant)0Direct
Poly(ADP-ribose) polymerase, C-terminal domain0Direct
MPP-like0Direct
Isoprenyl diphosphate synthases0Direct
Transcriptional factor domain0Direct
FCH domain0Direct
MMP N-terminal domain0Direct
Troponin I0Direct
AAT-like0Direct
Matrix metalloproteases, catalytic domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
UBC-related0Direct
Rhomboid-like0Direct
Eukaryotic ODC-like0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
Hormone receptor domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
JAB1/MPN domain0Direct
C1 set domains (antibody constant domain-like)0Direct
Tandem AAA-ATPase domain0Direct
FAS1 domain0Direct
YWTD domain0Direct
HSP90 C-terminal domain0Direct
Paired domain0Direct
Fatty acid binding protein-like0Direct
Plakin repeat0Direct
Zf-UBP0Direct
Proteasome subunits0Direct
Amylase, catalytic domain0Direct
Sedlin (SEDL)0Direct
Ubiquitin activating enzymes (UBA)0Direct
NADPH-cytochrome p450 reductase-like0Direct
NTF2-like0Direct
alpha-mannosidase, C-terminal domain0Direct
Adenain-like0Direct
Transcription factor IIA (TFIIA), alpha-helical domain0Direct
Cofilin-like0Direct
F1F0 ATP synthase subunit C0Direct
Formin homology 2 domain (FH2 domain)0Direct
Carboxylesterase0Direct
Thrombospondin C-terminal domain0Direct
CBS-domain pair0Direct
Somatomedin B domain0Direct
Thyroglobulin type-1 domain0Direct
Rap/Ran-GAP0Direct
Parvalbumin0Direct
MIT domain0Direct
SWIRM domain0Direct
ATP-dependent DNA ligase catalytic domain0Direct
PB1 domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
N-acetyl transferase, NAT0Direct
DNA/RNA non-specific endonuclease0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
Tubulin, C-terminal domain0Direct
Formate/glycerate dehydrogenases, substrate-binding domain0Direct
Clathrin coat assembly domain0Direct
Prefoldin0Direct
Calponin-homology domain, CH-domain0Direct
Succinyl-CoA synthetase domains0Direct
Proton glutamate symport protein0Direct
28-residue LRR0Direct
APC10-like0Direct
BAG domain0Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0Direct
Cytoplasmic domain of inward rectifier potassium channel0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
Class I aldolase0Direct
Alcohol dehydrogenase-like, N-terminal domain0Direct
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain0Direct
Alpha-macroglobulin receptor domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Nitrogenase iron protein-like0Direct
Diacylglycerol kinase-like0Direct
DEP domain0Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
Netrin-like domain (NTR/C345C module)0Direct
Filamin repeat (rod domain)0Direct
Fucose binding lectin0Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0Direct
Myosin rod fragments0Direct
WD40-repeat0Direct
AlkB-like0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0Direct
BC C-terminal domain-like0Direct
SMAD domain0Direct
PDZ domain0Direct
WWE domain0Direct
Toll/Interleukin receptor TIR domain0Direct
Mannose 6-phosphate receptor domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
DBL homology domain (DH-domain)0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
IF2B-like0Direct
La domain0Direct
P4 origin-binding domain-like0Direct
BRK domain-like0Direct
Ephrin receptor ligand binding domain0Direct
Ran-binding domain0Direct
SNARE fusion complex0Direct
Astacin0Direct
Bacterial exopeptidase dimerisation domain0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
SNF-like0Direct
E2F dimerization segment0Direct
Integrin A (or I) domain0Direct
BTG domain-like0Direct
KRAB domain (Kruppel-associated box)0Direct
PA domain0Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0Direct
Extracellular domain of cell surface receptors0Direct
Elongation factor TFIIS domain 20Direct
Ribonuclease PH domain 2-like0Direct
Sec7 domain0Direct
Tropomyosin0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Cu,Zn superoxide dismutase-like0Direct
Alpha-adaptin ear subdomain-like0Direct
EF-G/eEF-2 domains III and V0Direct
GRAM domain0Direct
Roadblock/LC7 domain0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
eIF1-like0Direct
Acyl-CoA binding protein0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Nuclear receptor0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Calcium ATPase, transmembrane domain M0Direct
PDEase0Direct
PAZ domain0Direct
STAR domain0Direct
Laminin G-like module0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Nucleotide and nucleoside kinases0Direct
Laminin-type module0Direct
Deoxycytidylate deaminase-like0Direct
Glycerophosphoryl diester phosphodiesterase0Direct
Eferin C-derminal domain-like0Direct
RhoGDI-like0Direct
Ammonium transporter0Direct
BCR-homology GTPase activation domain (BH-domain)0Direct
Histone lysine methyltransferases0Direct
THAP domain0Direct
Nop domain0Direct
Adenylyl and guanylyl cyclase catalytic domain0Direct
Diap1 N-terninal region-like0Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain0Direct
Complement control module/SCR domain0Direct
Tudor domain0Direct
Animal lipoxigenases0Direct
L27 domain0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Cystatins0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
F-box domain0Direct
Synatpobrevin N-terminal domain0Direct
GABA-aminotransferase-like0Direct
SRF-like0Direct
Elongation factors0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Frizzled cysteine-rich domain0Direct
MYND zinc finger0Direct
PLC-like (P variant)0Direct
Lamin A/C globular tail domain0Direct
Aldo-keto reductases (NADP)0Direct
Transcription factor IIA (TFIIA), beta-barrel domain0Direct
MHC antigen-recognition domain0Direct
VWC domain0Direct
Actin/HSP700Direct
MATH domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0Direct
PKD domain0Direct
Ephrin ectodomain0Direct
CUT domain0Direct
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)0Direct
BC ATP-binding domain-like0Direct
Protein kinases, catalytic subunit0.04761Inherited
G proteins0.176Inherited
Canonical RBD0.2651Inherited
Eukaryotic proteases0.7461Inherited
HMG-box0.764Inherited
SH2 domain0.7811Inherited
Leucine zipper domain0.856Inherited
CCCH zinc finger0.9153Inherited
Fibroblast growth factors (FGF)0.9842Inherited
Calmodulin-like1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Transforming growth factor (TGF)-beta1Inherited
Homeodomain1Inherited
POU-specific domain1Inherited
Hairy Orange domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SAP domain0Direct
DUSP-like0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
MIR domain0Direct
R3H domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
ARM repeat0Direct
A heparin-binding domain0Direct
HRDC-like0Direct
vWA-like0Direct
Nucleotidyltransferase0Direct
TGS-like0Direct
LeuD/IlvD-like0Direct
RBP11-like subunits of RNA polymerase0Direct
Intermediate filament protein, coiled coil region0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
TRAF domain-like0Direct
Fibrinogen C-terminal domain-like0Direct
E2F-DP heterodimerization region0Direct
GroEL apical domain-like0Direct
Radical SAM enzymes0Direct
UBA-like0Direct
GAT-like domain0Direct
Zinc beta-ribbon0Direct
SMAD/FHA domain0Direct
BRCT domain0Direct
SCP-like0Direct
SMAD MH1 domain0Direct
E set domains0Direct
DNase I-like0Direct
NagB/RpiA/CoA transferase-like0Direct
occludin/ELL-like0Direct
Nucleotide cyclase0Direct
Elongation factor TFIIS domain 20Direct
Plakin repeat0Direct
GST C-terminal domain-like0Direct
UBC-like0Direct
RmlC-like cupins0Direct
Hect, E3 ligase catalytic domain0Direct
Synuclein0Direct
Second domain of FERM0Direct
Acyl-CoA binding protein0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Seven-hairpin glycosidases0Direct
Nucleotidylyl transferase0Direct
Nicotinic receptor ligand binding domain-like0Direct
Cupredoxins0Direct
Thiolase-like0Direct
Frizzled cysteine-rich domain0Direct
Serpins0Direct
Cu,Zn superoxide dismutase-like0Direct
Tubulin nucleotide-binding domain-like0Direct
Cytidine deaminase-like0Direct
FnI-like domain0Direct
PR-1-like0Direct
Subunits of heterodimeric actin filament capping protein Capz0Direct
DPP6 N-terminal domain-like0Direct
2Fe-2S ferredoxin-like0Direct
TSP type-3 repeat0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
Tubulin C-terminal domain-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
eIF4e-like0Direct
PKD domain0Direct
Dimeric alpha+beta barrel0Direct
Cytochrome b5-like heme/steroid binding domain0Direct
Actin-like ATPase domain0Direct
C-type lectin-like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Amidase signature (AS) enzymes0Direct
Chaperone J-domain0Direct
Subtilisin-like0Direct
SNARE-like0Direct
PapD-like0Direct
PLP-dependent transferases0Direct
DNA polymerase beta, N-terminal domain-like0Direct
PGBD-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
ArfGap/RecO-like zinc finger0Direct
Mob1/phocein0Direct
Bacterial exopeptidase dimerisation domain0Direct
Putative DNA-binding domain0Direct
DNA-binding domain0Direct
MHC antigen-recognition domain0Direct
CoA-dependent acyltransferases0Direct
HIT-like0Direct
Lipoxigenase0Direct
WD40 repeat-like0Direct
Mannose 6-phosphate receptor domain0Direct
Metallo-hydrolase/oxidoreductase0Direct
GAF domain-like0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Macro domain-like0Direct
Calponin-homology domain, CH-domain0Direct
ATP-dependent DNA ligase DNA-binding domain0Direct
ENTH/VHS domain0Direct
Class II aaRS ABD-related0Direct
Periplasmic binding protein-like I0Direct
Integrin domains0Direct
Carbohydrate phosphatase0Direct
Bcl-2 inhibitors of programmed cell death0Direct
Creatinase/prolidase N-terminal domain0Direct
Succinyl-CoA synthetase domains0Direct
LEM domain0Direct
Sm-like ribonucleoproteins0Direct
NAD(P)-linked oxidoreductase0Direct
Periplasmic binding protein-like II0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Snake toxin-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
SpoIIaa-like0Direct
Galactose mutarotase-like0Direct
Neurotransmitter-gated ion-channel transmembrane pore0Direct
GHMP Kinase, C-terminal domain0Direct
DNA-glycosylase0Direct
Pectin lyase-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
SAM/Pointed domain0Direct
Pentein0Direct
Hedgehog/DD-peptidase0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Myosin phosphatase inhibitor 17kDa protein, CPI-170Direct
Metallo-dependent phosphatases0Direct
Protease propeptides/inhibitors0Direct
L30e-like0Direct
CAD & PB1 domains0Direct
t-snare proteins0Direct
SOCS box-like0Direct
NTF2-like0Direct
Somatomedin B domain0Direct
3-carboxy-cis,cis-mucoante lactonizing enzyme0Direct
Pseudouridine synthase0Direct
Tricorn protease domain 20Direct
Polo-box domain0Direct
RuvA domain 2-like0Direct
Calpain large subunit, middle domain (domain III)0Direct
GTPase activation domain, GAP0Direct
Phosphoglucomutase, first 3 domains0Direct
RCC1/BLIP-II0Direct
ARID-like0Direct
PYP-like sensor domain (PAS domain)0Direct
USP8 N-terminal domain-like0Direct
PABC (PABP) domain0Direct
Sec7 domain0Direct
GLA-domain0Direct
Delta-sleep-inducing peptide immunoreactive peptide0Direct
Cyclin-like0Direct
Nucleic acid-binding proteins0Direct
Cullin homology domain0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Smc hinge domain0Direct
TK C-terminal domain-like0Direct
FMN-linked oxidoreductases0Direct
TNF receptor-like0Direct
Ras GEF0Direct
Lipocalins0Direct
Calcium ATPase, transduction domain A0Direct
PDZ domain-like0Direct
RNase III domain-like0Direct
SNF-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Ribosomal L27 protein-like0Direct
Integrin alpha N-terminal domain0Direct
SNARE fusion complex0Direct
AN1-like Zinc finger0Direct
Carbonic anhydrase0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
GroEL-intermediate domain like0Direct
eIF1-like0Direct
FYVE/PHD zinc finger0Direct
B-box zinc-binding domain0Direct
TIMP-like0Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0Direct
Tudor/PWWP/MBT0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
BTG domain-like0Direct
PX domain0Direct
Hormone receptor domain0Direct
Nudix0Direct
Calcium-dependent phosphotriesterase0Direct
post-AAA+ oligomerization domain-like0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
PreATP-grasp domain0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Cation efflux protein transmembrane domain-like0Direct
ABC transporter transmembrane region0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
Alkaline phosphatase-like0Direct
Chromo domain-like0Direct
NAP-like0Direct
Terpenoid synthases0Direct
HSP90 C-terminal domain0Direct
FF domain0Direct
Glycosyl hydrolase domain0Direct
Ribonuclease PH domain 2-like0Direct
Hemopexin-like domain0Direct
Translational machinery components0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Zn-dependent exopeptidases0Direct
GINS helical bundle-like0Direct
Ribosomal proteins L15p and L18e0Direct
Eferin C-derminal domain-like0Direct
Ribokinase-like0Direct
Composite domain of metallo-dependent hydrolases0Direct
Adenine nucleotide alpha hydrolases-like0Direct
PAZ domain0Direct
gamma-Crystallin-like0Direct
Tubby C-terminal domain-like0Direct
PP2C-like0Direct
Metallo-dependent hydrolases0Direct
Plexin repeat0Direct
ValRS/IleRS/LeuRS editing domain0Direct
HCP-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Insulin-like0Direct
Supernatant protein factor (SPF), C-terminal domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
TATA-box binding protein-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Voltage-gated potassium channels0Direct
Myosin rod fragments0Direct
KRAB domain (Kruppel-associated box)0Direct
GroEL equatorial domain-like0Direct
HIT/MYND zinc finger-like0Direct
F1F0 ATP synthase subunit C0Direct
Sec1/munc18-like (SM) proteins0Direct
Thyroglobulin type-1 domain0Direct
SET domain0Direct
Glutathione synthetase ATP-binding domain-like0Direct
Phosphoglucomutase, C-terminal domain0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
CBS-domain pair0Direct
L27 domain0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
Growth factor receptor domain0Direct
C-terminal domain of adenylylcyclase associated protein0Direct
Annexin0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Globin-like0Direct
Surp module (SWAP domain)0Direct
Alanine racemase C-terminal domain-like0Direct
PLP-binding barrel0Direct
FAS1 domain0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Sema domain0Direct
4Fe-4S ferredoxins0Direct
Nuclear receptor coactivator interlocking domain0Direct
Acetyl-CoA synthetase-like0Direct
Inosine monophosphate dehydrogenase (IMPDH)0Direct
Ribonuclease H-like0Direct
Class I glutamine amidotransferase-like0Direct
Carbon-nitrogen hydrolase0Direct
14-3-3 protein0Direct
Rhomboid-like0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Enolase C-terminal domain-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Rudiment single hybrid motif0Direct
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain0Direct
PA domain0Direct
Cullin repeat-like0Direct
DNA clamp0Direct
Bromodomain0Direct
MIT domain0Direct
Cystatin/monellin0Direct
Di-copper centre-containing domain0Direct
Nop domain0Direct
ThrRS/AlaRS common domain0Direct
S15/NS1 RNA-binding domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
HD-domain/PDEase-like0Direct
Caspase-like0Direct
Complement control module/SCR domain0Direct
Ammonium transporter0Direct
THUMP domain-like0Direct
KA1-like0Direct
Tropomyosin0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Six-hairpin glycosidases0Direct
Spectrin repeat0Direct
Galactose oxidase, central domain0Direct
SWIB/MDM2 domain0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Formyltransferase0Direct
Clavaminate synthase-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
NAD(P)-binding Rossmann-fold domains0Direct
Ribosomal protein S5 domain 2-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Ran binding protein zinc finger-like0Direct
NAD kinase/diacylglycerol kinase-like0Direct
VPS9 domain0Direct
Transcription factor IIA (TFIIA), beta-barrel domain0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
PriA/YqbF domain0Direct
L-aspartase-like0Direct
FabD/lysophospholipase-like0Direct
Clc chloride channel0Direct
SRCR-like0Direct
BSD domain-like0Direct
Stathmin0Direct
PRTase-like0Direct
Kelch motif0Direct
Roadblock/LC7 domain0Direct
alpha-catenin/vinculin-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Cation efflux protein cytoplasmic domain-like0Direct
SAICAR synthase-like0Direct
LDH C-terminal domain-like0Direct
Troponin coil-coiled subunits0Direct
Outer arm dynein light chain 10Direct
Fibronectin type III0Direct
PAP/OAS1 substrate-binding domain0Direct
Mss4-like0Direct
WW domain0Direct
Zn-binding ribosomal proteins0Direct
Guanido kinase N-terminal domain0Direct
Nucleoplasmin-like core domain0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
NHL repeat0Direct
LuxS/MPP-like metallohydrolase0Direct
Single hybrid motif0Direct
LDL receptor-like module0Direct
AraD/HMP-PK domain-like0Direct
DHS-like NAD/FAD-binding domain0Direct
Formin homology 2 domain (FH2 domain)0Direct
Kazal-type serine protease inhibitors0Direct
Rap/Ran-GAP0Direct
VHP, Villin headpiece domain0Direct
ADP-ribosylation0Direct
Bet v1-like0Direct
DLC0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
Acid proteases0Direct
MAPEG domain-like0Direct
Cap-Gly domain0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Clathrin adaptor appendage domain0Direct
RUN domain-like0Direct
TSP-1 type 1 repeat0Direct
ClpP/crotonase0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Proton glutamate symport protein0Direct
Ricin B-like lectins0Direct
F-box domain0Direct
Endosomal sorting complex assembly domain0Direct
Calcium ATPase, transmembrane domain M0Direct
BRK domain-like0Direct
Moesin tail domain0Direct
Oxysterol-binding protein-like0Direct
Cadherin-like0Direct
PLC-like phosphodiesterases0Direct
Ferritin-like0Direct
beta-sandwich domain of Sec23/240Direct
p53-like transcription factors0Direct
Glycoside hydrolase/deacetylase0Direct
Acyl-CoA dehydrogenase NM domain-like0Direct
Galactose-binding domain-like0Direct
Restriction endonuclease-like0Direct
Cyclophilin-like0Direct
JAB1/MPN domain0Direct
PUA domain-like0Direct
ALDH-like0Direct
"Winged helix" DNA-binding domain0Direct
Connexin430Direct
Cysteine alpha-hairpin motif0Direct
SRF-like0Direct
Acyl-CoA dehydrogenase C-terminal domain-like0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
DNA/RNA polymerases0Direct
Cysteine proteinases0Direct
Phospholipase D/nuclease0Direct
Mib/herc2 domain-like0Direct
His-Me finger endonucleases0Direct
Sec63 N-terminal domain-like0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
DBL homology domain (DH-domain)0Direct
FAD/NAD(P)-binding domain0Direct
Class II aaRS and biotin synthetases0Direct
EF-G C-terminal domain-like0Direct
Prefoldin0Direct
Band 7/SPFH domain0Direct
Enolase N-terminal domain-like0Direct
Proteasome activator0Direct
Translation proteins0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
YWTD domain0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Arginase/deacetylase0Direct
ACT-like0Direct
BPTI-like0Direct
FAD-linked reductases, C-terminal domain0Direct
Apolipoprotein A-I0Direct
WWE domain0Direct
Creatinase/aminopeptidase0Direct
Glutamine synthetase/guanido kinase0Direct
Translation proteins SH3-like domain0Direct
Carboxypeptidase regulatory domain-like0Direct
Tim10-like0Direct
Aconitase iron-sulfur domain0Direct
Transducin (alpha subunit), insertion domain0Direct
Aldolase0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0Direct
Riboflavin synthase domain-like0Direct
BAG domain0Direct
Alpha-macroglobulin receptor domain0Direct
Transcription factor IIA (TFIIA), alpha-helical domain0Direct
Flavoproteins0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Tetraspanin0Direct
Trefoil0Direct
Mitochondrial carrier0Direct
GroES-like0Direct
Uracil-DNA glycosylase-like0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
dsRNA-binding domain-like0Direct
Nucleoside diphosphate kinase, NDK0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Actin-crosslinking proteins0Direct
Lamin A/C globular tail domain0Direct
Phosphoglycerate mutase-like0Direct
Protein kinase-like (PK-like)0.04057Inherited
PH domain-like0.151Inherited
RNA-binding domain, RBD0.2149Inherited
RING/U-box0.2501Inherited
Ubiquitin-like0.4291Inherited
Thioredoxin-like0.5434Inherited
EGF/Laminin0.6264Inherited
EF-hand0.6751Inherited
Trypsin-like serine proteases0.734Inherited
Immunoglobulin0.7549Inherited
HMG-box0.7825Inherited
SH2 domain0.7998Inherited
Leucine zipper domain0.871Inherited
Concanavalin A-like lectins/glucanases0.9149Inherited
CCCH zinc finger0.9267Inherited
Acyl-CoA N-acyltransferases (Nat)0.9267Inherited
Cytokine0.9941Inherited
Cystine-knot cytokines1Inherited
Homeodomain-like1Inherited
Orange domain-like1Inherited
lambda repressor-like DNA-binding domains1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    53187,49464
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    53448,50370
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 50370 - Ricin B-like lectins
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    54631,54631
  • 54631 - CBS-domain pair
  • 54631 - CBS-domain pair
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    54534,47473
  • 54534 - FKBP-like
  • 47473 - EF-hand
  • 0Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0Direct
    52540,48340
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48340 - Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
  • 0Direct
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    55945,55945
  • 55945 - TATA-box binding protein-like
  • 55945 - TATA-box binding protein-like
  • 0Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0Direct
    46942,57783
  • 46942 - Elongation factor TFIIS domain 2
  • 57783 - Zinc beta-ribbon
  • 0Direct
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0Direct
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    55486,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    47473,103506
  • 47473 - EF-hand
  • 103506 - Mitochondrial carrier
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    117018,56091
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0Direct
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0Direct
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    52087,101576
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0Direct
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    48403,158235
  • 48403 - Ankyrin repeat
  • 158235 - SOCS box-like
  • 0Direct
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57184,100895
  • 57184 - Growth factor receptor domain
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50494,50494
  • 50494 - Trypsin-like serine proteases
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0Direct
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0Direct
    82895,57424
  • 82895 - TSP-1 type 1 repeat
  • 57424 - LDL receptor-like module
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    81383,52047
  • 81383 - F-box domain
  • 52047 - RNI-like
  • 0Direct
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    81296,48239
  • 81296 - E set domains
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 0Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    50729,48350
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    48403,50044
  • 48403 - Ankyrin repeat
  • 50044 - SH3-domain
  • 0Direct
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    46785,54928
  • 46785 - "Winged helix" DNA-binding domain
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0Direct
    48350,50729
  • 48350 - GTPase activation domain, GAP
  • 50729 - PH domain-like
  • 0Direct
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0Direct
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0Direct
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0Direct
    57196,56436
  • 57196 - EGF/Laminin
  • 56436 - C-type lectin-like
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    103657,50044
  • 103657 - BAR/IMD domain-like
  • 50044 - SH3-domain
  • 0Direct
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0Direct
    47203,47203
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.6337Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.7584Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 1Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 1Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    64268,50044,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    90229,90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49854,49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    56645,47203,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    46938,52087,101576
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 101576 - Supernatant protein factor (SPF), C-terminal domain
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    57196,49854,57196
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    55486,49854,49854
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0Direct
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    103657,50729,48350
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0Direct
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 0Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0Direct
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50447,54980,54211
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    117018,56091,50249
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.5929Inherited


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