SUPERFAMILY 1.75 HMM library and genome assignments server

Worm Phenotype (WP): behavior variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Variant [WBPhenotype:0000886] <5>
0:   behavior variant [WBPhenotype:0000517] <1>(75|64) (75|32|11)
- 1:   organism behavior variant [WBPhenotype:0000525] <20>(73|64) (73|32|11)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
S-adenosylmethionine synthetase0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Troponin coil-coiled subunits0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
GINS helical bundle-like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Histone-fold0.000000006866Direct
Homeodomain-like0.00000001359Direct
PH domain-like0.00000005003Direct
HLH, helix-loop-helix DNA-binding domain0.00000007369Direct
Periplasmic binding protein-like I0.000000515Direct
Protein kinase-like (PK-like)0.000001613Direct
ARM repeat0.000001743Direct
Band 7/SPFH domain0.000002053Direct
"Winged helix" DNA-binding domain0.000003487Direct
Bromodomain0.000007747Direct
TPR-like0.000008299Direct
Insulin-like0.00005682Direct
P-loop containing nucleoside triphosphate hydrolases0.00008539Direct
Growth factor receptor domain0.0001287Direct
beta-beta-alpha zinc fingers0.0001373Direct
Spectrin repeat0.000155Direct
Hedgehog/intein (Hint) domain0.000155Direct
Prefoldin0.0001734Direct
Nucleotide cyclase0.0002077Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0003691Direct
Cysteine-rich domain0.0003739Direct
Calponin-homology domain, CH-domain0.0003782Direct
Tropomyosin0.0004542Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0004786Direct
RNA-binding domain, RBD0.0005033Direct
Class I glutamine amidotransferase-like0.0006736Direct
Voltage-gated potassium channels0.0007548Direct
EGF/Laminin0.0007968Direct
Tubulin C-terminal domain-like0.0008834Direct
Immunoglobulin0.001411Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001556Inherited
cAMP-binding domain-like0.002274Inherited
PYP-like sensor domain (PAS domain)0.00238Inherited
SH3-domain0.002578Inherited
Nicotinic receptor ligand binding domain-like0.002587Inherited
Tubulin nucleotide-binding domain-like0.002615Inherited
Actin-like ATPase domain0.002714Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.003158Inherited
Smc hinge domain0.003158Inherited
Subtilisin-like0.003263Inherited
Integrin domains0.003263Inherited
Clathrin adaptor appendage domain0.003263Inherited
E2F-DP heterodimerization region0.003263Inherited
ADC-like0.003263Inherited
Cdc48 domain 2-like0.003263Inherited
WD40 repeat-like0.003492Inherited
PDZ domain-like0.005296Inherited
DBL homology domain (DH-domain)0.007227Inherited
PLC-like phosphodiesterases0.0122Inherited
Periplasmic binding protein-like II0.0122Inherited
FKBP-like0.01863Inherited
Arginase/deacetylase0.01863Inherited
Intermediate filament protein, coiled coil region0.0202Inherited
Lamin A/C globular tail domain0.0202Inherited
Fibronectin type III0.02364Inherited
EF-hand0.02559Inherited
Myosin rod fragments0.03368Inherited
Regulator of G-protein signaling, RGS0.0504Inherited
Quinoprotein alcohol dehydrogenase-like0.07932Inherited
DNase I-like0.1341Inherited
NAD kinase/diacylglycerol kinase-like0.1825Inherited
Transducin (alpha subunit), insertion domain0.1896Inherited
SAM/Pointed domain0.2242Inherited
PLP-dependent transferases0.2846Inherited
LDL receptor-like module0.4478Inherited
Saposin0.4879Inherited
Ankyrin repeat0.803Inherited
Nuclear receptor ligand-binding domain1Inherited
Family A G protein-coupled receptor-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Mammalian PLC0Direct
S-adenosylmethionine synthetase0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Troponin I0Direct
Integrin domains0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Laminin-type module0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
RhoGDI-like0Direct
Multidrug efflux transporter AcrB transmembrane domain0.000000000000002751Direct
Homeodomain0.00000007252Direct
Nucleosome core histones0.0000001944Direct
Pleckstrin-homology domain (PH domain)0.000000376Direct
HLH, helix-loop-helix DNA-binding domain0.000001521Direct
Proteasome subunits0.000002555Direct
Band 7/SPFH domain0.00000378Direct
PLC-like (P variant)0.000007432Direct
PDZ domain0.00002875Direct
Bromodomain0.00003412Direct
Rhodopsin-like0.00003548Direct
Actin/HSP700.00007631Direct
Spectrin repeat0.0001121Direct
Protein kinases, catalytic subunit0.0001141Direct
L-arabinose binding protein-like0.0002317Direct
Canonical RBD0.0002379Direct
Insulin-like0.0002873Direct
Growth factor receptor domain0.000313Direct
Hedgehog C-terminal (Hog) autoprocessing domain0.000431Direct
Tropomyosin0.001225Inherited
Smc hinge domain0.001234Inherited
Adenylyl and guanylyl cyclase catalytic domain0.001489Inherited
Clathrin coat assembly domain0.001569Inherited
cAMP-binding domain0.002852Inherited
Tubulin, C-terminal domain0.002855Inherited
I set domains0.003464Inherited
LIM domain0.003804Inherited
Cell cycle transcription factor e2f-dp0.005142Inherited
WD40-repeat0.00532Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.005664Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.00623Inherited
Tubulin, GTPase domain0.007241Inherited
Nicotinic receptor ligand binding domain-like0.01007Inherited
Pyridoxal-dependent decarboxylase0.0113Inherited
Motor proteins0.01146Inherited
Phosphate binding protein-like0.01522Inherited
Histone deacetylase, HDAC0.01536Inherited
DBL homology domain (DH-domain)0.01878Inherited
FKBP immunophilin/proline isomerase0.03201Inherited
Intermediate filament protein, coiled coil region0.03801Inherited
Voltage-gated potassium channels0.05037Inherited
Myosin rod fragments0.05639Inherited
Lamin A/C globular tail domain0.05639Inherited
G proteins0.06933Inherited
Regulator of G-protein signaling, RGS0.07852Inherited
Fibronectin type III0.07933Inherited
EGF-type module0.08363Inherited
Tetramerization domain of potassium channels0.2511Inherited
Transducin (alpha subunit), insertion domain0.3124Inherited
Synaptotagmin-like (S variant)0.3422Inherited
LDL receptor-like module0.6022Inherited
Integrin A (or I) domain0.669Inherited
Ankyrin repeat0.9715Inherited
Nuclear receptor ligand-binding domain1Inherited
Nuclear receptor1Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
GINS helical bundle-like0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Troponin coil-coiled subunits0Direct
S-adenosylmethionine synthetase0Direct
Histone-fold0.000000005543Direct
Homeodomain-like0.00000001099Direct
PH domain-like0.00000004054Direct
HLH, helix-loop-helix DNA-binding domain0.00000005975Direct
Periplasmic binding protein-like I0.0000004196Direct
Protein kinase-like (PK-like)0.000001317Direct
ARM repeat0.000001423Direct
Band 7/SPFH domain0.000001677Direct
"Winged helix" DNA-binding domain0.00000285Direct
Bromodomain0.000006345Direct
TPR-like0.000006796Direct
Insulin-like0.00004689Direct
P-loop containing nucleoside triphosphate hydrolases0.00007059Direct
Growth factor receptor domain0.0001063Direct
beta-beta-alpha zinc fingers0.0001134Direct
Spectrin repeat0.0001282Direct
Hedgehog/intein (Hint) domain0.0001282Direct
Prefoldin0.0001435Direct
Nucleotide cyclase0.0001722Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0003073Direct
Cysteine-rich domain0.0003113Direct
Calponin-homology domain, CH-domain0.000315Direct
Tropomyosin0.0003789Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0003994Direct
RNA-binding domain, RBD0.0004202Direct
Class I glutamine amidotransferase-like0.0005636Direct
Voltage-gated potassium channels0.0006318Direct
EGF/Laminin0.0006675Direct
Tubulin C-terminal domain-like0.0007407Direct
Immunoglobulin0.001189Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001312Inherited
cAMP-binding domain-like0.001925Inherited
PYP-like sensor domain (PAS domain)0.002014Inherited
SH3-domain0.002182Inherited
Nicotinic receptor ligand binding domain-like0.00219Inherited
Tubulin nucleotide-binding domain-like0.002213Inherited
Actin-like ATPase domain0.002298Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.002676Inherited
Smc hinge domain0.002676Inherited
Cdc48 domain 2-like0.002766Inherited
E2F-DP heterodimerization region0.002766Inherited
Subtilisin-like0.002766Inherited
Integrin domains0.002766Inherited
ADC-like0.002766Inherited
Clathrin adaptor appendage domain0.002766Inherited
WD40 repeat-like0.002962Inherited
PDZ domain-like0.004515Inherited
DBL homology domain (DH-domain)0.006191Inherited
Periplasmic binding protein-like II0.01051Inherited
PLC-like phosphodiesterases0.01051Inherited
FKBP-like0.01617Inherited
Arginase/deacetylase0.01617Inherited
Intermediate filament protein, coiled coil region0.01756Inherited
Lamin A/C globular tail domain0.01756Inherited
Fibronectin type III0.0206Inherited
EF-hand0.02235Inherited
Myosin rod fragments0.02955Inherited
Regulator of G-protein signaling, RGS0.04462Inherited
Quinoprotein alcohol dehydrogenase-like0.07093Inherited
DNase I-like0.1218Inherited
NAD kinase/diacylglycerol kinase-like0.1676Inherited
Transducin (alpha subunit), insertion domain0.1744Inherited
SAM/Pointed domain0.2073Inherited
PLP-dependent transferases0.2655Inherited
LDL receptor-like module0.4252Inherited
Saposin0.4656Inherited
Ankyrin repeat0.7854Inherited
Nuclear receptor ligand-binding domain1Inherited
Family A G protein-coupled receptor-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000005421Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00002252Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0003994Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0004565Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0004565Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.0005636Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.0006917Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0007484Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0008922Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.001194Inherited
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.001398Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.002014Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.002213Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.002766Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.002766Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.002766Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.003642Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.004868Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.007501Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.01051Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.02863Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05282Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1744Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2184Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57362,57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0005919Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.002014Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.009835Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0237Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0725Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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