SUPERFAMILY 1.75 HMM library and genome assignments server

Mammalian Phenotype (MP): vision/eye phenotype

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <30>
0:   vision/eye phenotype [MP:0005391] <2>(42|53) (52|24|14)
- 1:   abnormal eye physiology [MP:0005253] <24>(8|11) (11|4|1)
- 1:   abnormal eye morphology [MP:0002092] <20>(38|48) (46|23|13)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Di-copper centre-containing domain0Direct
Tubby C-terminal domain-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
gamma-Crystallin-like0Direct
Homeodomain-like0.0001574Direct
Cystine-knot cytokines0.0004981Direct
FnI-like domain0.0005046Direct
EGF/Laminin0.0005856Direct
Plexin repeat0.001161Inherited
CalX-like0.001777Inherited
ALDH-like0.001777Inherited
YWTD domain0.002009Inherited
HLH, helix-loop-helix DNA-binding domain0.01948Inherited
Sema domain0.02126Inherited
GAF domain-like0.02137Inherited
Nuclear receptor ligand-binding domain0.0252Inherited
LDL receptor-like module0.03997Inherited
E2F-DP heterodimerization region0.06921Inherited
TNF-like0.07369Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.08237Inherited
CBS-domain pair0.08545Inherited
Transducin (heterotrimeric G protein), gamma chain0.1003Inherited
Clc chloride channel0.1003Inherited
Cyclin-like0.1111Inherited
Kringle-like0.1547Inherited
Tetraspanin0.2544Inherited
HD-domain/PDEase-like0.2544Inherited
PGBD-like0.3077Inherited
Blood coagulation inhibitor (disintegrin)0.3077Inherited
Transducin (alpha subunit), insertion domain0.3396Inherited
"Winged helix" DNA-binding domain0.4008Inherited
Toll/Interleukin receptor TIR domain0.415Inherited
L domain-like0.4479Inherited
Nicotinic receptor ligand binding domain-like0.4998Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4998Inherited
NAD(P)-binding Rossmann-fold domains0.6126Inherited
GTPase activation domain, GAP0.6368Inherited
DBL homology domain (DH-domain)0.7369Inherited
Metalloproteases ("zincins"), catalytic domain0.7374Inherited
Immunoglobulin0.8615Inherited
Trypsin-like serine proteases0.9767Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Transcriptional factor tubby, C-terminal domain0Direct
Retinoblastoma tumor suppressor domains0Direct
p53 tetramerization domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Crystallins/Ca-binding development proteins0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
p53 DNA-binding domain-like0Direct
Homeodomain0.0000547Direct
VWC domain0.000179Direct
Arylsulfatase0.0003013Direct
Plexin repeat0.0008665Direct
CalX-beta domain0.001207Inherited
ALDH-like0.001207Inherited
Integrin beta tail domain0.001207Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.001209Inherited
Noncollagenous (NC1) domain of collagen IV0.001209Inherited
NADPH-cytochrome p450 reductase-like0.001209Inherited
YWTD domain0.001408Inherited
Forkhead DNA-binding domain0.003204Inherited
I set domains0.01331Inherited
Transforming growth factor (TGF)-beta0.01437Inherited
Nuclear receptor0.01439Inherited
GAF domain0.0161Inherited
Sema domain0.01714Inherited
HLH, helix-loop-helix DNA-binding domain0.01719Inherited
Nuclear receptor ligand-binding domain0.02102Inherited
LDL receptor-like module0.03255Inherited
E2F dimerization segment0.03295Inherited
TNF-like0.06226Inherited
Laminin-type module0.06255Inherited
CBS-domain pair0.07091Inherited
Clc chloride channel0.08374Inherited
Tyrosine-dependent oxidoreductases0.08862Inherited
Cell cycle transcription factor e2f-dp0.1163Inherited
Kringle modules0.1507Inherited
Calmodulin-like0.1709Inherited
PDEase0.1902Inherited
Ngr ectodomain-like0.235Inherited
MMP N-terminal domain0.2835Inherited
Blood coagulation inhibitor (disintegrin)0.2835Inherited
Transducin (alpha subunit), insertion domain0.3133Inherited
Matrix metalloproteases, catalytic domain0.3193Inherited
PDZ domain0.3275Inherited
Cyclin0.3561Inherited
Fibronectin type III0.3718Inherited
SH3-domain0.4536Inherited
cAMP-binding domain0.4623Inherited
Nicotinic receptor ligand binding domain-like0.4787Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4787Inherited
Intermediate filament protein, coiled coil region0.5973Inherited
DBL homology domain (DH-domain)0.7235Inherited
Rhodopsin-like0.9619Inherited
Eukaryotic proteases0.9927Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
gamma-Crystallin-like0Direct
Di-copper centre-containing domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
Tubby C-terminal domain-like0Direct
Homeodomain-like0.00008462Direct
Cystine-knot cytokines0.000279Direct
FnI-like domain0.0002832Direct
EGF/Laminin0.0003311Direct
Plexin repeat0.0006663Direct
Integrin beta tail domain0.001042Inherited
ALDH-like0.001042Inherited
CalX-like0.001042Inherited
YWTD domain0.001183Inherited
Alkaline phosphatase-like0.001371Inherited
Growth factor receptor domain0.002006Inherited
HLH, helix-loop-helix DNA-binding domain0.01308Inherited
Sema domain0.01438Inherited
GAF domain-like0.01446Inherited
Nuclear receptor ligand-binding domain0.01724Inherited
LDL receptor-like module0.02827Inherited
E2F-DP heterodimerization region0.05128Inherited
TNF-like0.05487Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.06207Inherited
CBS-domain pair0.06454Inherited
Transducin (heterotrimeric G protein), gamma chain0.07697Inherited
Clc chloride channel0.07697Inherited
beta-sandwich domain of Sec23/240.07697Inherited
Cyclin-like0.08618Inherited
Kringle-like0.124Inherited
HD-domain/PDEase-like0.2153Inherited
Tetraspanin0.2153Inherited
Blood coagulation inhibitor (disintegrin)0.2651Inherited
PGBD-like0.2651Inherited
Transducin (alpha subunit), insertion domain0.2953Inherited
Fibronectin type III0.3286Inherited
"Winged helix" DNA-binding domain0.3546Inherited
Toll/Interleukin receptor TIR domain0.3684Inherited
L domain-like0.4005Inherited
SH3-domain0.4074Inherited
Nicotinic receptor ligand binding domain-like0.4525Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4525Inherited
cAMP-binding domain-like0.5385Inherited
NAD(P)-binding Rossmann-fold domains0.5664Inherited
Intermediate filament protein, coiled coil region0.5692Inherited
GTPase activation domain, GAP0.5917Inherited
DBL homology domain (DH-domain)0.6957Inherited
Metalloproteases ("zincins"), catalytic domain0.6963Inherited
Immunoglobulin0.828Inherited
Trypsin-like serine proteases0.9548Inherited
Voltage-gated potassium channels0.9631Inherited
Family A G protein-coupled receptor-like0.9834Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001461Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.001042Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.002211Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.006434Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.009584Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.009584Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01076Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.01438Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01446Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.01446Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01828Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.05128Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0686Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.06949Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.07697Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.1566Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.1775Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.2651Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.2651Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2953Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.4525Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.6957Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.001042Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001557Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.00402Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.006643Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.006643Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.01446Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01446Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.01446Inherited
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01828Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.03503Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)