SUPERFAMILY 1.75 HMM library and genome assignments server

Mammalian Phenotype (MP): limbs/digits/tail phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <30>
0:   limbs/digits/tail phenotype [MP:0005371] <2>(14|23) (17|15|14)
- 1:   abnormal tail morphology [MP:0002111] <18>(1|2) (1|2|0)
- 1:   abnormal limb morphology [MP:0002109] <13>(10|20) (13|12|14)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0.000001487Direct
Growth factor receptor domain0.00001682Direct
FnI-like domain0.00003118Direct
p53-like transcription factors0.00004552Direct
TSP type-3 repeat0.0002559Direct
Kringle-like0.008769Inherited
LDL receptor-like module0.01127Inherited
CalX-like0.0199Inherited
YWTD domain0.02789Inherited
Hemopexin-like domain0.06484Inherited
Cystine-knot cytokines0.07816Inherited
PGBD-like0.1011Inherited
Intermediate filament protein, coiled coil region0.1313Inherited
SAM/Pointed domain0.762Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Homeodomain0.0000007649Direct
Growth factor receptor domain0.0000286Direct
VWC domain0.00006174Direct
T-box0.0001025Direct
TSP type-3 repeat0.0001534Direct
DIX domain0.0001534Direct
Thrombospondin C-terminal domain0.0001534Direct
ZZ domain0.0003203Direct
HMG-box0.001066Inherited
LDL receptor-like module0.008122Inherited
CalX-beta domain0.01453Inherited
Link domain0.01478Inherited
YWTD domain0.02093Inherited
Transforming growth factor (TGF)-beta0.02855Inherited
Kringle modules0.03668Inherited
Ovomucoid domain III-like0.03668Inherited
Hemopexin-like domain0.05168Inherited
MMP N-terminal domain0.08337Inherited
Matrix metalloproteases, catalytic domain0.0981Inherited
Reprolysin-like0.108Inherited
Intermediate filament protein, coiled coil region0.1124Inherited
SAM (sterile alpha motif) domain0.1985Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Homeodomain-like0.000000707Direct
Growth factor receptor domain0.000008408Direct
FnI-like domain0.00001605Direct
p53-like transcription factors0.00002373Direct
TSP type-3 repeat0.0001393Direct
HMG-box0.0009109Direct
Kringle-like0.005601Inherited
LDL receptor-like module0.007304Inherited
CalX-like0.01339Inherited
YWTD domain0.01919Inherited
Hemopexin-like domain0.04773Inherited
Cystine-knot cytokines0.05856Inherited
Metalloproteases ("zincins"), catalytic domain0.0621Inherited
PGBD-like0.07767Inherited
Intermediate filament protein, coiled coil region0.1038Inherited
Cyclin-like0.1063Inherited
SAM/Pointed domain0.7221Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0001393Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.0001393Direct
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.0001393Direct
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001393Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0005836Direct
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.0009605Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0009632Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001525Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.003165Inherited
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0.007415Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.009019Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.01339Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02593Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.07767Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1477Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.0001393Direct
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0001393Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0005459Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0005836Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0005836Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.0009605Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.001525Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.003319Inherited
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.007415Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.007415Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.04341Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.07228Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1271Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.2815Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)