SUPERFAMILY 1.75 HMM library and genome assignments server

Mammalian Phenotype (MP): renal/urinary system phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <30>
0:   renal/urinary system phenotype [MP:0005367] <2>(34|37) (36|15|8)
- 1:   abnormal renal/urinary system morphology [MP:0000516] <12>(25|26) (28|12|7)
- 1:   abnormal renal/urinary system physiology [MP:0005502] <6>(17|15) (19|6|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Families 57/38 glycoside transferase middle domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Growth factor receptor domain0.000003725Direct
(Trans)glycosidases0.00005522Direct
EGF/Laminin0.0001778Direct
Aquaporin-like0.0003241Direct
Phoshotransferase/anion transport protein0.0005288Direct
Glycoside hydrolase/deacetylase0.0008992Direct
Clc chloride channel0.002134Inherited
CBS-domain pair0.00252Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00252Inherited
Riboflavin synthase domain-like0.00252Inherited
Galactose mutarotase-like0.003309Inherited
MFS general substrate transporter0.006491Inherited
CalX-like0.007922Inherited
Flavoproteins0.007922Inherited
FnI-like domain0.02158Inherited
Acyl-CoA dehydrogenase NM domain-like0.02664Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.02664Inherited
L30e-like0.02664Inherited
Toll/Interleukin receptor TIR domain0.02913Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.04915Inherited
Nuclear receptor ligand-binding domain0.06684Inherited
C-type lectin-like0.1001Inherited
TNF receptor-like0.1175Inherited
Integrin domains0.1195Inherited
TPR-like0.1516Inherited
Family A G protein-coupled receptor-like0.3274Inherited
Cadherin-like0.3772Inherited
Metalloproteases ("zincins"), catalytic domain0.4088Inherited
Cytokine0.457Inherited
Nicotinic receptor ligand binding domain-like0.5311Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.5311Inherited
Homeodomain-like0.9225Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
alpha-mannosidase, domain 20Direct
alpha-mannosidase, C-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
alpha-mannosidase0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Growth factor receptor domain0.00001442Direct
Arylsulfatase0.00009792Direct
Aquaporin-like0.0001918Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0005482Direct
NADPH-cytochrome p450 reductase-like0.0005482Direct
Clc chloride channel0.001364Inherited
Anion transport protein, cytoplasmic domain0.001364Inherited
CBS-domain pair0.001632Inherited
VWC domain0.002993Inherited
EGF-type module0.003716Inherited
CalX-beta domain0.005342Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.009062Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.009062Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.009442Inherited
Platelet-derived growth factor-like0.01047Inherited
Toll/Interleukin receptor TIR domain0.01653Inherited
Tetratricopeptide repeat (TPR)0.01662Inherited
Laminin-type module0.02928Inherited
PLC-like (P variant)0.03297Inherited
Nuclear receptor0.04005Inherited
Nuclear receptor ligand-binding domain0.05281Inherited
Transforming growth factor (TGF)-beta0.05423Inherited
Bcl-2 inhibitors of programmed cell death0.0981Inherited
Integrin domains0.09884Inherited
TNF receptor-like0.1112Inherited
Rhodopsin-like0.1509Inherited
Fibroblast growth factors (FGF)0.2515Inherited
Cadherin0.3197Inherited
Nicotinic receptor ligand binding domain-like0.4964Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4964Inherited
I set domains0.5913Inherited
Leucine zipper domain0.7023Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0Direct
Growth factor receptor domain0.000001802Direct
(Trans)glycosidases0.00002916Direct
EGF/Laminin0.0000958Direct
Aquaporin-like0.0001783Direct
Phoshotransferase/anion transport protein0.0002969Direct
Glycoside hydrolase/deacetylase0.0005129Direct
Clc chloride channel0.001264Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.001507Inherited
CBS-domain pair0.001507Inherited
Riboflavin synthase domain-like0.001507Inherited
Galactose mutarotase-like0.002005Inherited
MFS general substrate transporter0.004079Inherited
CalX-like0.005023Inherited
Flavoproteins0.005023Inherited
FnI-like domain0.01462Inherited
L30e-like0.01828Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01828Inherited
Acyl-CoA dehydrogenase NM domain-like0.01828Inherited
Toll/Interleukin receptor TIR domain0.0201Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.0353Inherited
Nuclear receptor ligand-binding domain0.04932Inherited
C-type lectin-like0.07687Inherited
TNF receptor-like0.09176Inherited
Bcl-2 inhibitors of programmed cell death0.09342Inherited
Integrin domains0.09347Inherited
TPR-like0.1214Inherited
Family A G protein-coupled receptor-like0.2838Inherited
Cadherin-like0.3313Inherited
Metalloproteases ("zincins"), catalytic domain0.3624Inherited
Cytokine0.4095Inherited
Nicotinic receptor ligand binding domain-like0.4836Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4836Inherited
Leucine zipper domain0.6878Inherited
Homeodomain-like0.894Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0002736Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002324Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.003831Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.005023Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.008206Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01701Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01828Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.01828Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.07999Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.1481Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.2098Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4003Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.4788Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.4836Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.002005Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002771Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.004587Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.004669Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03177Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.06494Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.343Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4134Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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